Inhalable microspheres embedding chitosan-coated PLGA nanoparticles for 2-methoxyestradiol

Journal of Drug Targeting

Volumn 22, Issue 5, 2014, Pages 421-427

  Guo, Xinhong ^a   Zhang, Xinxin ^a   Ye, Ling ^a   Zhang, Ying ^a   Ding, Rui ^a   Hao, Yongwei ^a   Zhao, Yalin ^a   Zhang, Zhenzhong ^a   Zhang, Yun ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Cytotoxicity; Fine particle fraction; in vivo; Inflammation; Local lung delivery; Spray drying

Indexed keywords

2 METHOXYESTRADIOL; CHITOSAN; MICROSPHERE; NANOPARTICLE; POLYLACTIC ACID; 2-METHOXYESTRADIOL; ANTINEOPLASTIC AGENT; DRUG CARRIER; ESTRADIOL; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; EMBEDDING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INTRAPULMONARY DRUG ADMINISTRATION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SPRAY DRYING; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM; PATHOLOGY; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ADMINISTRATION, INHALATION; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; ESTRADIOL; HUMANS; LACTIC ACID; LUNG; MICROSPHERES; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 84901021117     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2013.878944     Document Type: Article

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