Formulation and in vitro characterization of inhalable polyvinyl alcohol-free rifampicin-loaded PLGA microspheres prepared with sucrose palmitate as stabilizer: Efficiency for ex vivo alveolar macrophage targeting

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 833-839

  Diab, R ^a,b,c   Brillault, J ^a,b   Bardy, A ^a,b   Gontijo, A V L ^a,b,d   Olivier, J C ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE POITIERS   (France)

^c UNIVERSITÉ DE LORRAINE   (France)

^d MINISTRY OF EDUCATION OF BRAZIL   (Brazil)

Author keywords

Alveolar macrophage; Cell uptake; PLGA microsphere; Rifampicin; Sucrose palmitate

Indexed keywords

MICROSPHERE; ORGANIC SOLVENT; POLYGLACTIN; POLYVINYL ALCOHOL; RIFAMPICIN; SUCROSE PALMITATE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; EVAPORATION; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; MALE; MICROENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; CELL SURVIVAL; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; LACTIC ACID; MACROPHAGES, ALVEOLAR; MALE; MICROSPHERES; POLYGLYCOLIC ACID; POLYVINYL ALCOHOL; RATS; RATS, SPRAGUE-DAWLEY; RIFAMPIN; SUCROSE;

EID: 84865799323     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.07.036     Document Type: Article

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