An ionizable active-site tryptophan imparts catalase activity to a peroxidase core

Journal of the American Chemical Society

Volumn 136, Issue 20, 2014, Pages 7249-7252

  Loewen, Peter C ^a   Carpena, Xavi ^b   Vidossich, Pietro ^d   Fita, Ignacio ^c   Rovira, Carme ^e,f  

^a UNIVERSITY OF MANITOBA   (Canada)

^b INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^c INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

^f INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; X RAY CRYSTALLOGRAPHY;

BI-FUNCTIONAL; CATALASE ACTIVITY; CATALASE-PEROXIDASE; ELECTRONIC SWITCHES; HEME PROTEINS; MONOFUNCTIONAL CATALASE; QM/MM CALCULATIONS; STRUCTURAL DISSIMILARITIES;

PLANTS (BOTANY);

CATALASE; HEME; HYDROGEN PEROXIDE; PEROXIDASE; TRYPTOPHAN;

ARTICLE; CALCULATION; CONFORMATION; CONTROLLED STUDY; CRYSTAL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROGEN BOND; IONIZATION; PROTON TRANSPORT; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; METABOLISM; PH; QUANTUM THEORY;

CATALASE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; PEROXIDASES; QUANTUM THEORY; TRYPTOPHAN;

EID: 84901020346     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja502794e     Document Type: Article

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