메뉴 건너뛰기




Volumn 109, Issue 12, 2013, Pages 3092-3104

Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; LUCIFERASE; MICRORNA 200B; MICRORNA 200C; PROTEIN; ROCK2 PROTEIN; SMALL INTERFERING RNA; SUZ12 PROTEIN; UNCLASSIFIED DRUG;

EID: 84890425122     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.655     Document Type: Article
Times cited : (85)

References (34)
  • 1
    • 84871928731 scopus 로고    scopus 로고
    • Interferon-gamma activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype
    • Almontashiri NA, Fan M, Cheng BL, Chen HH, Roberts R, Stewart AF (2013) Interferon-gamma activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype. J Am Coll Cardiol 61(2): 143-147.
    • (2013) J Am Coll Cardiol , vol.61 , Issue.2 , pp. 143-147
    • Almontashiri, N.A.1    Fan, M.2    Cheng, B.L.3    Chen, H.H.4    Roberts, R.5    Stewart, A.F.6
  • 2
    • 47149112544 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Advances in pathogenesis, diagnosis, and treatment
    • Blechacz B, Gores GJ (2008) Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology 48(1): 308-321.
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 308-321
    • Blechacz, B.1    Gores, G.J.2
  • 3
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9(6): 582-589.
    • (2008) EMBO Rep , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 4
    • 77954863985 scopus 로고    scopus 로고
    • Loss of miR-200c: A marker of aggressiveness and chemoresistance in female reproductive cancers
    • Cochrane DR, Howe EN, Spoelstra NS, Richer JK (2010) Loss of miR-200c: a marker of aggressiveness and chemoresistance in female reproductive cancers. J Oncol 2010: 821717.
    • (2010) J Oncol , vol.2010 , pp. 821717
    • Cochrane, D.R.1    Howe, E.N.2    Spoelstra, N.S.3    Richer, J.K.4
  • 6
    • 84887023225 scopus 로고    scopus 로고
    • On the role of Notch1 and adult hepatocytes in murine intrahepatic cholangiocarcinoma development
    • e-pub ahead of print 23 March 2013 doi:10.1002/hep.26411
    • Evert M, Dombrowski F, Biao F, Ribback S, Chen X, Calvisi DF (2013) On the role of Notch1 and adult hepatocytes in murine intrahepatic cholangiocarcinoma development. Hepatology; e-pub ahead of print 23 March 2013; doi:10.1002/hep.26411.
    • (2013) Hepatology
    • Evert, M.1    Dombrowski, F.2    Biao, F.3    Ribback, S.4    Chen, X.5    Calvisi, D.F.6
  • 7
    • 84864360562 scopus 로고    scopus 로고
    • Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
    • Gheldof A, Hulpiau P, van Roy F, De Craene B, Berx G (2012) Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cell Mol Life Sci 69(15): 2527-2541.
    • (2012) Cell Mol Life Sci , vol.69 , Issue.15 , pp. 2527-2541
    • Gheldof, A.1    Hulpiau, P.2    Van Roy, F.3    De Craene, B.4    Berx, G.5
  • 8
    • 84881303278 scopus 로고    scopus 로고
    • Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition
    • e-pub ahead of print 14 January 2013; doi:10.1038/onc.2012.573
    • Guo L, Chen C, Shi M, Wang F, Chen X, Diao D, Hu M, Yu M, Qian L, Guo N (2013) Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition. Oncogene; e-pub ahead of print 14 January 2013; doi:10.1038/onc.2012.573.
    • (2013) Oncogene
    • Guo, L.1    Chen, C.2    Shi, M.3    Wang, F.4    Chen, X.5    Diao, D.6    Hu, M.7    Yu, M.8    Qian, L.9    Guo, N.10
  • 9
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He L, Hannon GJ (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5(7): 522-531.
    • (2004) Nat Rev Genet , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 10
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1(3): 313-323.
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 12
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K (2010) Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol cell 39(5): 761-772.
    • (2010) Mol Cell , vol.39 , Issue.5 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3    Hirsch, H.A.4    Tsichlis, P.N.5    Struhl, K.6
  • 13
    • 34848927455 scopus 로고    scopus 로고
    • The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila
    • Karres JS, Hilgers V, Carrera I, Treisman J, Cohen SM (2007) The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 131(1): 136-145.
    • (2007) Cell , vol.131 , Issue.1 , pp. 136-145
    • Karres, J.S.1    Hilgers, V.2    Carrera, I.3    Treisman, J.4    Cohen, S.M.5
  • 18
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y (2008) The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283(22): 14910-14914.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 19
    • 77954354936 scopus 로고    scopus 로고
    • Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels
    • Li A, Omura N, Hong SM, Vincent A, Walter K, Griffith M, Borges M, Goggins M (2010) Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels. Cancer Res 70(13): 5226-5237.
    • (2010) Cancer Res , vol.70 , Issue.13 , pp. 5226-5237
    • Li, A.1    Omura, N.2    Hong, S.M.3    Vincent, A.4    Walter, K.5    Griffith, M.6    Borges, M.7    Goggins, M.8
  • 20
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME (2008) The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22(7): 894-907.
    • (2008) Genes Dev , vol.22 , Issue.7 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 23
    • 77955507555 scopus 로고    scopus 로고
    • MiR-200c regulates induction of apoptosis through CD95 by targeting FAP-1
    • Schickel R, Park SM, Murmann AE, Peter ME (2010) miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1. Mol Cell 38(6): 908-915.
    • (2010) Mol Cell , vol.38 , Issue.6 , pp. 908-915
    • Schickel, R.1    Park, S.M.2    Murmann, A.E.3    Peter, M.E.4
  • 25
    • 84865328547 scopus 로고    scopus 로고
    • Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer
    • Soubani O, Ali AS, Logna F, Ali S, Philip PA, Sarkar FH (2012) Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. Carcinogenesis 33(8): 1563-1571.
    • (2012) Carcinogenesis , vol.33 , Issue.8 , pp. 1563-1571
    • Soubani, O.1    Ali, A.S.2    Logna, F.3    Ali, S.4    Philip, P.A.5    Sarkar, F.H.6
  • 26
    • 84891929773 scopus 로고    scopus 로고
    • WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
    • e-pub ahead of print January 14 2013 doi:10.1038/onc.2012.565
    • Teng Y, Mei Y, Hawthorn L, Cowell JK (2013) WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells. Oncogene. e-pub ahead of print January 14 2013; doi:10.1038/onc.2012.565.
    • (2013) Oncogene
    • Teng, Y.1    Mei, Y.2    Hawthorn, L.3    Cowell, J.K.4
  • 28
    • 63049101157 scopus 로고    scopus 로고
    • The role of the ZEB family of transcription factors in development and disease
    • Vandewalle C, Van Roy F, Berx G (2009) The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci 66(5): 773-787.
    • (2009) Cell Mol Life Sci , vol.66 , Issue.5 , pp. 773-787
    • Vandewalle, C.1    Van Roy, F.2    Berx, G.3
  • 29
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8(10): 755-768.
    • (2008) Nat Rev Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 30
    • 79951996059 scopus 로고    scopus 로고
    • CD133 and ALDH may be the molecular markers of cholangiocarcinoma stem cells
    • Wang M, Xiao J, Jiang J, Qin R (2011a) CD133 and ALDH may be the molecular markers of cholangiocarcinoma stem cells. Int J Cancer 128(8): 1996-1997.
    • (2011) Int J Cancer , vol.128 , Issue.8 , pp. 1996-1997
    • Wang, M.1    Xiao, J.2    Jiang, J.3    Qin, R.4
  • 31
    • 78349276876 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties
    • Wang M, Xiao J, Shen M, Yahong Y, Tian R, Zhu F, Jiang J, Du Z, Hu J, Liu W, Qin R (2011b) Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties. Int J Cancer 128(1): 72-81.
    • (2011) Int J Cancer , vol.128 , Issue.1 , pp. 72-81
    • Wang, M.1    Xiao, J.2    Shen, M.3    Yahong, Y.4    Tian, R.5    Zhu, F.6    Jiang, J.7    Du, Z.8    Hu, J.9    Liu, W.10    Qin, R.11
  • 34
    • 84874789694 scopus 로고    scopus 로고
    • Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma
    • Zhang L, Yang F, Yuan JH, Yuan SX, Zhou WP, Huo XS, Xu D, Bi HS, Wang F, Sun SH (2013) Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma. Carcinogenesis 34(3): 577-586.
    • (2013) Carcinogenesis , vol.34 , Issue.3 , pp. 577-586
    • Zhang, L.1    Yang, F.2    Yuan, J.H.3    Yuan, S.X.4    Zhou, W.P.5    Huo, X.S.6    Xu, D.7    Bi, H.S.8    Wang, F.9    Sun, S.H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.