메뉴 건너뛰기




Volumn 46, Issue 4, 2013, Pages 436-446

Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BREAST CANCER RESISTANCE PROTEIN; MICRORNA 200C; MICRORNA 20A; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; VIMENTIN;

EID: 84880668080     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/cpr.12038     Document Type: Article
Times cited : (80)

References (44)
  • 1
    • 0036365026 scopus 로고    scopus 로고
    • Current diagnosis and treatment modalities for ovarian cancer
    • Schwartz PE (2002) Current diagnosis and treatment modalities for ovarian cancer. Cancer Treat. Res. 107, 99-118.
    • (2002) Cancer Treat. Res. , vol.107 , pp. 99-118
    • Schwartz, P.E.1
  • 4
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3, 730-737.
    • (1997) Nat. Med. , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 8
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 9
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 11
    • 65349132693 scopus 로고    scopus 로고
    • EMT, the cytoskeleton, and cancer cell invasion
    • Yilmaz M, Christofori G (2009) EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev. 28, 15-33.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 15-33
    • Yilmaz, M.1    Christofori, G.2
  • 12
    • 84861344069 scopus 로고    scopus 로고
    • Tissue transglutaminase links TGF-beta, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer
    • Cao L, Shao M, Schilder J, Guise T, Mohammad KS, Matei D (2012) Tissue transglutaminase links TGF-beta, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer. Oncogene 31, 2521-2534.
    • (2012) Oncogene , vol.31 , pp. 2521-2534
    • Cao, L.1    Shao, M.2    Schilder, J.3    Guise, T.4    Mohammad, K.S.5    Matei, D.6
  • 13
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvagner G, Zamore PD (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science 297, 2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2
  • 14
    • 70349145414 scopus 로고    scopus 로고
    • MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
    • Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y et al. (2009) MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev. 23, 2152-2165.
    • (2009) Genes Dev. , vol.23 , pp. 2152-2165
    • Olson, P.1    Lu, J.2    Zhang, H.3    Shai, A.4    Chun, M.G.5    Wang, Y.6
  • 15
    • 84860335557 scopus 로고    scopus 로고
    • Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells
    • Fu X, Tian J, Zhang L, Chen Y, Hao Q (2012) Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells. FEBS Lett. 586, 1279-1286.
    • (2012) FEBS Lett. , vol.586 , pp. 1279-1286
    • Fu, X.1    Tian, J.2    Zhang, L.3    Chen, Y.4    Hao, Q.5
  • 16
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • Yang H, Kong W, He L, Zhao JJ, O'Donnell JD, Wang J et al. (2008) MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 68, 425-433.
    • (2008) Cancer Res. , vol.68 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3    Zhao, J.J.4    O'Donnell, J.D.5    Wang, J.6
  • 19
    • 29144488505 scopus 로고    scopus 로고
    • Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition
    • Irie HY, Pearline RV, Grueneberg D, Hsia M, Ravichandran P, Kothari N et al. (2005) Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition. J. Cell Biol. 171, 1023-1034.
    • (2005) J. Cell Biol. , vol.171 , pp. 1023-1034
    • Irie, H.Y.1    Pearline, R.V.2    Grueneberg, D.3    Hsia, M.4    Ravichandran, P.5    Kothari, N.6
  • 20
    • 77950791817 scopus 로고    scopus 로고
    • Characterization of primary ovarian cancer cells in different culture systems
    • Liu T, Cheng W, Lai D, Huang Y, Guo L (2010) Characterization of primary ovarian cancer cells in different culture systems. Oncol. Rep. 23, 1277-1284.
    • (2010) Oncol. Rep. , vol.23 , pp. 1277-1284
    • Liu, T.1    Cheng, W.2    Lai, D.3    Huang, Y.4    Guo, L.5
  • 21
    • 77956279975 scopus 로고    scopus 로고
    • Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3
    • Ma L, Lai D, Liu T, Cheng W, Guo L (2010) Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3. Acta Biochim. Biophys. Sin. (Shanghai) 42, 593-602.
    • (2010) Acta Biochim. Biophys. Sin. (Shanghai) , vol.42 , pp. 593-602
    • Ma, L.1    Lai, D.2    Liu, T.3    Cheng, W.4    Guo, L.5
  • 23
    • 34547874440 scopus 로고    scopus 로고
    • Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche
    • Arai F, Suda T (2007) Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann. N. Y. Acad. Sci. 1106, 41-53.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1106 , pp. 41-53
    • Arai, F.1    Suda, T.2
  • 24
    • 38349132624 scopus 로고    scopus 로고
    • Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
    • Orford KW, Scadden DT (2008) Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat. Rev. Genet. 9, 115-128.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 115-128
    • Orford, K.W.1    Scadden, D.T.2
  • 26
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat SA, Mali AM, Koppikar CB, Kurrey NK (2005) Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res. 65, 3025-3029.
    • (2005) Cancer Res. , vol.65 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 27
    • 33746625091 scopus 로고    scopus 로고
    • Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness
    • Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R et al. (2006) Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness. Proc. Natl. Acad. Sci. USA 103, 11154-11159.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11154-11159
    • Szotek, P.P.1    Pieretti-Vanmarcke, R.2    Masiakos, P.T.3    Dinulescu, D.M.4    Connolly, D.5    Foster, R.6
  • 28
    • 16844368863 scopus 로고    scopus 로고
    • Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    • Elloul S, Elstrand MB, Nesland JM, Trope CG, Kvalheim G, Goldberg I et al. (2005) Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 103, 1631-1643.
    • (2005) Cancer , vol.103 , pp. 1631-1643
    • Elloul, S.1    Elstrand, M.B.2    Nesland, J.M.3    Trope, C.G.4    Kvalheim, G.5    Goldberg, I.6
  • 29
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • Christiansen JJ, Rajasekaran AK (2006) Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res. 66, 8319-8326.
    • (2006) Cancer Res. , vol.66 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 30
    • 79251540883 scopus 로고    scopus 로고
    • Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity
    • Strauss R, Li ZY, Liu Y, Beyer I, Persson J, Sova P et al. (2011) Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity. PLoS One 6, e16186.
    • (2011) PLoS One , vol.6
    • Strauss, R.1    Li, Z.Y.2    Liu, Y.3    Beyer, I.4    Persson, J.5    Sova, P.6
  • 31
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T (2005) Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat. Rev. Cancer 5, 744-749.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 32
    • 42649137241 scopus 로고    scopus 로고
    • Mechanisms of disease: epithelial-mesenchymal transition - does cellular plasticity fuel neoplastic progression?
    • Turley EA, Veiseh M, Radisky DC, Bissell MJ (2008) Mechanisms of disease: epithelial-mesenchymal transition - does cellular plasticity fuel neoplastic progression? Nat. Clin. Pract. Oncol. 5, 280-290.
    • (2008) Nat. Clin. Pract. Oncol. , vol.5 , pp. 280-290
    • Turley, E.A.1    Veiseh, M.2    Radisky, D.C.3    Bissell, M.J.4
  • 33
    • 80755173296 scopus 로고    scopus 로고
    • Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity
    • Drasin DJ, Robin TP, Ford HL (2011) Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity. Breast Cancer Res. 13, 226.
    • (2011) Breast Cancer Res. , vol.13 , pp. 226
    • Drasin, D.J.1    Robin, T.P.2    Ford, H.L.3
  • 34
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: new insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J. Cell Biol. 172, 973-981.
    • (2006) J. Cell Biol. , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 35
    • 33645124691 scopus 로고    scopus 로고
    • Immunohistochemical study of the expression of adhesion molecules in ovarian serous neoplasms
    • Cho EY, Choi Y, Chae SW, Sohn JH, Ahn GH (2006) Immunohistochemical study of the expression of adhesion molecules in ovarian serous neoplasms. Pathol. Int. 56, 62-70.
    • (2006) Pathol. Int. , vol.56 , pp. 62-70
    • Cho, E.Y.1    Choi, Y.2    Chae, S.W.3    Sohn, J.H.4    Ahn, G.H.5
  • 37
    • 79351468712 scopus 로고    scopus 로고
    • Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters
    • doi: 10.1186/1471-2407-11-49.
    • Li J, Zhou BP. (2011) Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer 11, 49. doi: 10.1186/1471-2407-11-49.
    • (2011) BMC Cancer , vol.11 , pp. 49
    • Li, J.1    Zhou, B.P.2
  • 38
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133, 647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 39
    • 84867500470 scopus 로고    scopus 로고
    • Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines
    • Gwak HS, Kim TH, Jo GH, Kim YJ, Kwak HJ, Kim JH et al. (2012) Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines. PLoS One 7, e47449.
    • (2012) PLoS One , vol.7
    • Gwak, H.S.1    Kim, T.H.2    Jo, G.H.3    Kim, Y.J.4    Kwak, H.J.5    Kim, J.H.6
  • 40
    • 77953806998 scopus 로고    scopus 로고
    • TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214
    • Yin G, Chen R, Alvero AB, Fu HH, Holmberg J, Glackin C et al. (2010) TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene 29, 3545-3553.
    • (2010) Oncogene , vol.29 , pp. 3545-3553
    • Yin, G.1    Chen, R.2    Alvero, A.B.3    Fu, H.H.4    Holmberg, J.5    Glackin, C.6
  • 41
    • 77951838369 scopus 로고    scopus 로고
    • miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells
    • Fan X, Liu Y, Jiang J, Ma Z, Wu H, Liu T et al. (2010) miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells. Acta Biochim. Biophys. Sin. (Shanghai) 42, 318-324.
    • (2010) Acta Biochim. Biophys. Sin. (Shanghai) , vol.42 , pp. 318-324
    • Fan, X.1    Liu, Y.2    Jiang, J.3    Ma, Z.4    Wu, H.5    Liu, T.6
  • 42
    • 77954863985 scopus 로고    scopus 로고
    • Loss of miR-200c: a marker of aggressiveness and chemoresistance in female reproductive cancers
    • Cochrane DR, Howe EN, Spoelstra NS, Richer JK (2010) Loss of miR-200c: a marker of aggressiveness and chemoresistance in female reproductive cancers. J Oncol. 2010, 821717.
    • (2010) J Oncol. , vol.2010 , pp. 821717
    • Cochrane, D.R.1    Howe, E.N.2    Spoelstra, N.S.3    Richer, J.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.