메뉴 건너뛰기




Volumn 15, Issue 1, 2014, Pages

The effects of salbutamol on epithelial ion channels depend on the etiology of acute respiratory distress syndrome but not the route of administration

Author keywords

Acute respiratory distress syndrome; Alveolar epithelial cells; Edema; Elastance; Epithelial sodium channel; Salbutamol

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AQUAPORIN; AQUAPORIN 1; AQUAPORIN 3; EPITHELIAL SODIUM CHANNEL; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; ION CHANNEL; SALBUTAMOL; SODIUM CHLORIDE;

EID: 84900863778     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-15-56     Document Type: Article
Times cited : (26)

References (40)
  • 1
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • 10.1056/NEJM200005043421806, 10793167
    • Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000, 342(18):1334-1349. 10.1056/NEJM200005043421806, 10793167.
    • (2000) N Engl J Med , vol.342 , Issue.18 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 2
    • 0034993527 scopus 로고    scopus 로고
    • Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
    • 10.1164/ajrccm.163.6.2004035, 11371404
    • Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001, 163(6):1376-1383. 10.1164/ajrccm.163.6.2004035, 11371404.
    • (2001) Am J Respir Crit Care Med , vol.163 , Issue.6 , pp. 1376-1383
    • Ware, L.B.1    Matthay, M.A.2
  • 3
    • 0025635795 scopus 로고
    • Intact epithelial barrier function is critical for the resolution of alveolar edema in humans
    • Matthay MA, Wiener-Kronish JP. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 1990, 142(6 Pt 1):1250-1257.
    • (1990) Am Rev Respir Dis , vol.142 , Issue.6 PART 1 , pp. 1250-1257
    • Matthay, M.A.1    Wiener-Kronish, J.P.2
  • 4
  • 6
    • 0022878762 scopus 로고
    • Beta-2-adrenoceptor agonists as inhibitors of lung vascular permeability to radiolabelled transferrin in the adult respiratory distress syndrome in man
    • Basran GS, Hardy JG, Woo SP, Ramasubramanian R, Byrne AJ. Beta-2-adrenoceptor agonists as inhibitors of lung vascular permeability to radiolabelled transferrin in the adult respiratory distress syndrome in man. Eur J Nucl Med 1986, 12(8):381-384.
    • (1986) Eur J Nucl Med , vol.12 , Issue.8 , pp. 381-384
    • Basran, G.S.1    Hardy, J.G.2    Woo, S.P.3    Ramasubramanian, R.4    Byrne, A.J.5
  • 7
    • 0029914850 scopus 로고    scopus 로고
    • Preservation of alveolar epithelial fluid transport mechanisms in rewarmed human lung after severe hypothermia
    • Sakuma T, Suzuki S, Usuda K, Handa M, Okaniwa G, Nakada T, Fujimura S, Matthay MA. Preservation of alveolar epithelial fluid transport mechanisms in rewarmed human lung after severe hypothermia. J Appl Physiol 1996, 80(5):1681-1686.
    • (1996) J Appl Physiol , vol.80 , Issue.5 , pp. 1681-1686
    • Sakuma, T.1    Suzuki, S.2    Usuda, K.3    Handa, M.4    Okaniwa, G.5    Nakada, T.6    Fujimura, S.7    Matthay, M.A.8
  • 8
    • 0031059873 scopus 로고    scopus 로고
    • Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs
    • 10.1164/ajrccm.155.2.9032186, 9032186
    • Sakuma T, Folkesson HG, Suzuki S, Okaniwa G, Fujimura S, Matthay MA. Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. Am J Respir Crit Care Med 1997, 155(2):506-512. 10.1164/ajrccm.155.2.9032186, 9032186.
    • (1997) Am J Respir Crit Care Med , vol.155 , Issue.2 , pp. 506-512
    • Sakuma, T.1    Folkesson, H.G.2    Suzuki, S.3    Okaniwa, G.4    Fujimura, S.5    Matthay, M.A.6
  • 9
    • 1042269499 scopus 로고    scopus 로고
    • Bench-to-bedside review: beta2-Agonists and the acute respiratory distress syndrome
    • 10.1186/cc2417, 420065, 14975042
    • Perkins GD, McAuley DF, Richter A, Thickett DR, Gao F. Bench-to-bedside review: beta2-Agonists and the acute respiratory distress syndrome. Crit Care 2004, 8(1):25-32. 10.1186/cc2417, 420065, 14975042.
    • (2004) Crit Care , vol.8 , Issue.1 , pp. 25-32
    • Perkins, G.D.1    McAuley, D.F.2    Richter, A.3    Thickett, D.R.4    Gao, F.5
  • 11
    • 84860894209 scopus 로고    scopus 로고
    • Anti-inflammatory effects of beta2 adrenergic receptor agonists in experimental acute lung injury
    • 10.1096/fj.11-201640, 3336792, 22318967
    • Bosmann M, Grailer JJ, Zhu K, Matthay MA, Sarma JV, Zetoune FS, Ward PA. Anti-inflammatory effects of beta2 adrenergic receptor agonists in experimental acute lung injury. FASEB J 2012, 26(5):2137-2144. 10.1096/fj.11-201640, 3336792, 22318967.
    • (2012) FASEB J , vol.26 , Issue.5 , pp. 2137-2144
    • Bosmann, M.1    Grailer, J.J.2    Zhu, K.3    Matthay, M.A.4    Sarma, J.V.5    Zetoune, F.S.6    Ward, P.A.7
  • 12
    • 3142721744 scopus 로고    scopus 로고
    • Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury
    • 10.1097/01.CCM.0000129489.34416.0E, 15241090
    • McAuley DF, Frank JA, Fang X, Matthay MA. Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med 2004, 32(7):1470-1476. 10.1097/01.CCM.0000129489.34416.0E, 15241090.
    • (2004) Crit Care Med , vol.32 , Issue.7 , pp. 1470-1476
    • McAuley, D.F.1    Frank, J.A.2    Fang, X.3    Matthay, M.A.4
  • 13
    • 0033778862 scopus 로고    scopus 로고
    • Beta-adrenergic agonist therapy accelerates the resolution of hydrostatic pulmonary edema in sheep and rats
    • Frank JA, Wang Y, Osorio O, Matthay MA. Beta-adrenergic agonist therapy accelerates the resolution of hydrostatic pulmonary edema in sheep and rats. J Appl Physiol 2000, 89(4):1255-1265.
    • (2000) J Appl Physiol , vol.89 , Issue.4 , pp. 1255-1265
    • Frank, J.A.1    Wang, Y.2    Osorio, O.3    Matthay, M.A.4
  • 14
    • 32144437063 scopus 로고    scopus 로고
    • The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial
    • 10.1164/rccm.200508-1302OC, 16254268
    • Perkins GD, McAuley DF, Thickett DR, Gao F. The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. Am J Respir Crit Care Med 2006, 173(3):281-287. 10.1164/rccm.200508-1302OC, 16254268.
    • (2006) Am J Respir Crit Care Med , vol.173 , Issue.3 , pp. 281-287
    • Perkins, G.D.1    McAuley, D.F.2    Thickett, D.R.3    Gao, F.4
  • 15
    • 84856102590 scopus 로고    scopus 로고
    • BALTI-2 study investigators: Effect of intravenous beta-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial
    • 10.1016/S0140-6736(11)61623-1, 3266479, 22166903
    • Gao Smith F, Perkins GD, Gates S, Young D, McAuley DF, Tunnicliffe W, Khan Z, Lamb SE. BALTI-2 study investigators: Effect of intravenous beta-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial. Lancet 2012, 379(9812):229-235. 10.1016/S0140-6736(11)61623-1, 3266479, 22166903.
    • (2012) Lancet , vol.379 , Issue.9812 , pp. 229-235
    • Gao Smith, F.1    Perkins, G.D.2    Gates, S.3    Young, D.4    McAuley, D.F.5    Tunnicliffe, W.6    Khan, Z.7    Lamb, S.E.8
  • 16
    • 79960430979 scopus 로고    scopus 로고
    • Randomized, placebo-controlled clinical trial of an aerosolized beta(2)-agonist for treatment of acute lung injury
    • 3175548, 21562125, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network
    • Heart N, Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT, . Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network Randomized, placebo-controlled clinical trial of an aerosolized beta(2)-agonist for treatment of acute lung injury. Am J Respir Crit Care Med 2011, 184(5):561-568. 3175548, 21562125, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network.
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.5 , pp. 561-568
    • Heart, N.1    Matthay, M.A.2    Brower, R.G.3    Carson, S.4    Douglas, I.S.5    Eisner, M.6    Hite, D.7    Holets, S.8    Kallet, R.H.9    Liu, K.D.10    MacIntyre, N.11    Moss, M.12    Schoenfeld, D.13    Steingrub, J.14    Thompson, B.T.15
  • 17
    • 17644390228 scopus 로고    scopus 로고
    • Pulmonary and extrapulmonary acute lung injury: inflammatory and ultrastructural analyses
    • 10.1152/japplphysiol.01182.2004, 15649870
    • Menezes SL, Bozza PT, Neto HC, Laranjeira AP, Negri EM, Capelozzi VL, Zin WA, Rocco PR. Pulmonary and extrapulmonary acute lung injury: inflammatory and ultrastructural analyses. J Appl Physiol 2005, 98(5):1777-1783. 10.1152/japplphysiol.01182.2004, 15649870.
    • (2005) J Appl Physiol , vol.98 , Issue.5 , pp. 1777-1783
    • Menezes, S.L.1    Bozza, P.T.2    Neto, H.C.3    Laranjeira, A.P.4    Negri, E.M.5    Capelozzi, V.L.6    Zin, W.A.7    Rocco, P.R.8
  • 20
    • 0019952025 scopus 로고
    • Use of microwave oven for determination of postmortem water volume of lungs
    • Peterson BT, Brooks JA, Zack AG. Use of microwave oven for determination of postmortem water volume of lungs. J Appl Physiol 1982, 52(6):1661-1663.
    • (1982) J Appl Physiol , vol.52 , Issue.6 , pp. 1661-1663
    • Peterson, B.T.1    Brooks, J.A.2    Zack, A.G.3
  • 21
    • 79953202454 scopus 로고    scopus 로고
    • Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support
    • 10.1097/CCM.0b013e318206bda6, 21263322
    • Spieth PM, Carvalho AR, Guldner A, Kasper M, Schubert R, Carvalho NC, Beda A, Dassow C, Uhlig S, Koch T, Pelosi P. Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support. Crit Care Med 2011, 39(4):746-755. 10.1097/CCM.0b013e318206bda6, 21263322.
    • (2011) Crit Care Med , vol.39 , Issue.4 , pp. 746-755
    • Spieth, P.M.1    Carvalho, A.R.2    Guldner, A.3    Kasper, M.4    Schubert, R.5    Carvalho, N.C.6    Beda, A.7    Dassow, C.8    Uhlig, S.9    Koch, T.10    Pelosi, P.11
  • 22
    • 79960124480 scopus 로고    scopus 로고
    • Experimental models and emerging hypotheses for acute lung injury
    • 10.1016/j.ccc.2011.05.013, 3159414, 21742226
    • Martin TR, Matute-Bello G. Experimental models and emerging hypotheses for acute lung injury. Crit Care Clin 2011, 27(3):735-752. 10.1016/j.ccc.2011.05.013, 3159414, 21742226.
    • (2011) Crit Care Clin , vol.27 , Issue.3 , pp. 735-752
    • Martin, T.R.1    Matute-Bello, G.2
  • 23
    • 0028018844 scopus 로고
    • Systemic effects of salbutamol and salmeterol in patients with asthma
    • 10.1136/thx.49.8.771, 475121, 8091321
    • Bennett JA, Smyth ET, Pavord ID, Wilding PJ, Tattersfield AE. Systemic effects of salbutamol and salmeterol in patients with asthma. Thorax 1994, 49(8):771-774. 10.1136/thx.49.8.771, 475121, 8091321.
    • (1994) Thorax , vol.49 , Issue.8 , pp. 771-774
    • Bennett, J.A.1    Smyth, E.T.2    Pavord, I.D.3    Wilding, P.J.4    Tattersfield, A.E.5
  • 24
    • 0033559334 scopus 로고    scopus 로고
    • Regulation of an amiloride-sensitive Na+-permeable channel by a beta2-adrenergic agonist, cytosolic Ca2+ and Cl- in fetal rat alveolar epithelium
    • 2269183, 10066896
    • Marunaka Y, Niisato N, O'Brodovich H, Eaton DC. Regulation of an amiloride-sensitive Na+-permeable channel by a beta2-adrenergic agonist, cytosolic Ca2+ and Cl- in fetal rat alveolar epithelium. J Physiol 1999, 515(Pt 3):669-683. 2269183, 10066896.
    • (1999) J Physiol , vol.515 , Issue.PART 3 , pp. 669-683
    • Marunaka, Y.1    Niisato, N.2    O'Brodovich, H.3    Eaton, D.C.4
  • 25
    • 0036087753 scopus 로고    scopus 로고
    • Beta-adrenergic regulation of amiloride-sensitive lung sodium channels
    • Chen XJ, Eaton DC, Jain L. Beta-adrenergic regulation of amiloride-sensitive lung sodium channels. Am J Physiol Lung Cell Mol Physiol 2002, 282(4):L609-L620.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282 , Issue.4
    • Chen, X.J.1    Eaton, D.C.2    Jain, L.3
  • 27
    • 74049135496 scopus 로고    scopus 로고
    • Lung parenchyma remodeling in acute respiratory distress syndrome
    • Rocco PR, Dos Santos C, Pelosi P. Lung parenchyma remodeling in acute respiratory distress syndrome. Minerva Anestesiol 2009, 75(12):730-740.
    • (2009) Minerva Anestesiol , vol.75 , Issue.12 , pp. 730-740
    • Rocco, P.R.1    Dos Santos, C.2    Pelosi, P.3
  • 28
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
    • 10.1038/36362, 9363896
    • Daaka Y, Luttrell LM, Lefkowitz RJ. Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997, 390(6655):88-91. 10.1038/36362, 9363896.
    • (1997) Nature , vol.390 , Issue.6655 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 29
    • 38549136704 scopus 로고    scopus 로고
    • Alveolar epithelial beta2-adrenergic receptors
    • 10.1165/rcmb.2007-0198TR, 2214676, 17709598
    • Mutlu GM, Factor P. Alveolar epithelial beta2-adrenergic receptors. Am J Respir Cell Mol Biol 2008, 38(2):127-134. 10.1165/rcmb.2007-0198TR, 2214676, 17709598.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , Issue.2 , pp. 127-134
    • Mutlu, G.M.1    Factor, P.2
  • 30
    • 84879534355 scopus 로고    scopus 로고
    • A feedback loop in PPARgamma-adenosine A2A receptor signaling inhibits inflammation and attenuates lung damages in a mouse model of LPS-induced acute lung injury
    • 10.1016/j.cellsig.2013.05.024, 23712033
    • He X, Hu JL, Li J, Zhao L, Zhang Y, Zeng YJ, Dai SS, He FT. A feedback loop in PPARgamma-adenosine A2A receptor signaling inhibits inflammation and attenuates lung damages in a mouse model of LPS-induced acute lung injury. Cell Signal 2013, 25(9):1913-1923. 10.1016/j.cellsig.2013.05.024, 23712033.
    • (2013) Cell Signal , vol.25 , Issue.9 , pp. 1913-1923
    • He, X.1    Hu, J.L.2    Li, J.3    Zhao, L.4    Zhang, Y.5    Zeng, Y.J.6    Dai, S.S.7    He, F.T.8
  • 31
    • 84883146421 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor 1, alpha subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts
    • 10.1165/rcmb.2012-0297OC, 23526216
    • Brant KA, Fabisiak JP. Role of hypoxia-inducible factor 1, alpha subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts. Am J Respir Cell Mol Biol 2013, 49(1):105-113. 10.1165/rcmb.2012-0297OC, 23526216.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.1 , pp. 105-113
    • Brant, K.A.1    Fabisiak, J.P.2
  • 32
    • 84858750300 scopus 로고    scopus 로고
    • The rise and fall of beta-agonists in the treatment of ARDS
    • 10.1186/cc11221, 3681353, 22429604
    • Bassford CR, Thickett DR, Perkins GD. The rise and fall of beta-agonists in the treatment of ARDS. Crit Care 2012, 16(2):208. 10.1186/cc11221, 3681353, 22429604.
    • (2012) Crit Care , vol.16 , Issue.2 , pp. 208
    • Bassford, C.R.1    Thickett, D.R.2    Perkins, G.D.3
  • 33
    • 0034836642 scopus 로고    scopus 로고
    • Norepinephrine induces alveolar epithelial apoptosis mediated by alpha-, beta-, and angiotensin receptor activation
    • Dincer HE, Gangopadhyay N, Wang R, Uhal BD. Norepinephrine induces alveolar epithelial apoptosis mediated by alpha-, beta-, and angiotensin receptor activation. Am J Physiol Lung Cell Mol Physiol 2001, 281(3):L624-L630.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281 , Issue.3
    • Dincer, H.E.1    Gangopadhyay, N.2    Wang, R.3    Uhal, B.D.4
  • 34
    • 0024380872 scopus 로고
    • Isoproterenol reduces thrombin-induced pulmonary endothelial permeability in vitro
    • Minnear FL, DeMichele MA, Moon DG, Rieder CL, Fenton JW. Isoproterenol reduces thrombin-induced pulmonary endothelial permeability in vitro. Am J Physiol 1989, 257(5 Pt 2):H1613-H1623.
    • (1989) Am J Physiol , vol.257 , Issue.5 PART 2
    • Minnear, F.L.1    DeMichele, M.A.2    Moon, D.G.3    Rieder, C.L.4    Fenton, J.W.5
  • 35
    • 40649106983 scopus 로고    scopus 로고
    • In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury
    • 10.1136/thx.2007.080382, 17951278
    • Perkins GD, Gao F, Thickett DR. In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury. Thorax 2008, 63(3):215-220. 10.1136/thx.2007.080382, 17951278.
    • (2008) Thorax , vol.63 , Issue.3 , pp. 215-220
    • Perkins, G.D.1    Gao, F.2    Thickett, D.R.3
  • 36
    • 84861849320 scopus 로고    scopus 로고
    • Beta-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo
    • 10.1152/ajplung.00038.2012, 3379040, 22505670
    • Downs CA, Kriener LH, Yu L, Eaton DC, Jain L, Helms MN. beta-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo. Am J Physiol Lung Cell Mol Physiol 2012, 302(11):L1167-L1178. 10.1152/ajplung.00038.2012, 3379040, 22505670.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , Issue.11
    • Downs, C.A.1    Kriener, L.H.2    Yu, L.3    Eaton, D.C.4    Jain, L.5    Helms, M.N.6
  • 37
    • 33845907698 scopus 로고    scopus 로고
    • Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms
    • 10.1016/j.cellsig.2006.06.007, 16996249
    • Tan KS, Nackley AG, Satterfield K, Maixner W, Diatchenko L, Flood PM. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cell Signal 2007, 19(2):251-260. 10.1016/j.cellsig.2006.06.007, 16996249.
    • (2007) Cell Signal , vol.19 , Issue.2 , pp. 251-260
    • Tan, K.S.1    Nackley, A.G.2    Satterfield, K.3    Maixner, W.4    Diatchenko, L.5    Flood, P.M.6
  • 38
    • 0027439417 scopus 로고
    • Respiratory mechanics and bronchodilator responsiveness in patients with the adult respiratory distress syndrome
    • 10.1097/00003246-199301000-00016, 8420734
    • Pesenti A, Pelosi P, Rossi N, Aprigliano M, Brazzi L, Fumagalli R. Respiratory mechanics and bronchodilator responsiveness in patients with the adult respiratory distress syndrome. Crit Care Med 1993, 21(1):78-83. 10.1097/00003246-199301000-00016, 8420734.
    • (1993) Crit Care Med , vol.21 , Issue.1 , pp. 78-83
    • Pesenti, A.1    Pelosi, P.2    Rossi, N.3    Aprigliano, M.4    Brazzi, L.5    Fumagalli, R.6
  • 39
    • 0031035143 scopus 로고    scopus 로고
    • Effects of nebulized salbutamol on respiratory mechanics in adult respiratory distress syndrome
    • 10.1007/s001340050291, 9037641
    • Morina P, Herrera M, Venegas J, Mora D, Rodriguez M, Pino E. Effects of nebulized salbutamol on respiratory mechanics in adult respiratory distress syndrome. Intensive Care Med 1997, 23(1):58-64. 10.1007/s001340050291, 9037641.
    • (1997) Intensive Care Med , vol.23 , Issue.1 , pp. 58-64
    • Morina, P.1    Herrera, M.2    Venegas, J.3    Mora, D.4    Rodriguez, M.5    Pino, E.6
  • 40
    • 79953017464 scopus 로고    scopus 로고
    • Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?
    • 10.1186/cc9994, 3219408, 21457509
    • Curley G, Hayes M, Laffey JG. Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?. Crit Care 2011, 15(2):212. 10.1186/cc9994, 3219408, 21457509.
    • (2011) Crit Care , vol.15 , Issue.2 , pp. 212
    • Curley, G.1    Hayes, M.2    Laffey, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.