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Volumn 406, Issue , 2014, Pages 83-103

Epitope distribution in ordered and disordered protein regions - Part A. T-cell epitope frequency, affinity and hydropathy

Author keywords

Disorder prediction; Epitope selection; Hydropathy prediction; T cell epitope prediction

Indexed keywords

AMINO ACID; DISORDERED PROTEIN; EPITOPE; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; ORDERED PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 84900860532     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2014.02.012     Document Type: Article
Times cited : (8)

References (63)
  • 1
    • 40349113184 scopus 로고    scopus 로고
    • Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming
    • Atanackovic D., Altorki N.K., Cao Y., Ritter E., Ferrara C.A., Ritter G., Gnjatic S. Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(5):1650. 10.1073/pnas.0707140104.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.5 , pp. 1650
    • Atanackovic, D.1    Altorki, N.K.2    Cao, Y.3    Ritter, E.4    Ferrara, C.A.5    Ritter, G.6    Gnjatic, S.7
  • 2
    • 78650895128 scopus 로고    scopus 로고
    • Towards universal structure-based prediction of class II MHC epitopes for diverse allotypes
    • Bordner A.J. Towards universal structure-based prediction of class II MHC epitopes for diverse allotypes. PLoS One 2010, 5(12):e14383. 10.1371/journal.pone.0014383.
    • (2010) PLoS One , vol.5 , Issue.12
    • Bordner, A.J.1
  • 3
    • 0141889127 scopus 로고    scopus 로고
    • Clustering of Th cell epitopes on exposed regions of HIV envelope despite defects in antibody activity
    • Brown S.A., Stambas J., Zhan X., Slobod K.S., Coleclough C., Zirkel A., Hurwitz J.L. Clustering of Th cell epitopes on exposed regions of HIV envelope despite defects in antibody activity. J. Immunol. 2003, 171(8):4140.
    • (2003) J. Immunol. , vol.171 , Issue.8 , pp. 4140
    • Brown, S.A.1    Stambas, J.2    Zhan, X.3    Slobod, K.S.4    Coleclough, C.5    Zirkel, A.6    Hurwitz, J.L.7
  • 4
    • 7944223046 scopus 로고    scopus 로고
    • Computational methods for prediction of T-cell epitopes - a framework for modelling, testing, and applications
    • Brusic V., Bajic V.B., Petrovsky N. Computational methods for prediction of T-cell epitopes - a framework for modelling, testing, and applications. Methods 2004, 34(4):436. 10.1016/j.ymeth.2004.06.006.
    • (2004) Methods , vol.34 , Issue.4 , pp. 436
    • Brusic, V.1    Bajic, V.B.2    Petrovsky, N.3
  • 5
    • 33644693375 scopus 로고    scopus 로고
    • Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity
    • Carl P.L., Temple B.R., Cohen P.L. Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity. Arthritis Res. Ther. 2005, 7(6):R1360. 10.1186/ar1832.
    • (2005) Arthritis Res. Ther. , vol.7 , Issue.6
    • Carl, P.L.1    Temple, B.R.2    Cohen, P.L.3
  • 6
    • 33748784872 scopus 로고    scopus 로고
    • Antigen three-dimensional structure guides the processing and presentation of helper T-cell epitopes
    • Carmicle S., Steede N.K., Landry S.J. Antigen three-dimensional structure guides the processing and presentation of helper T-cell epitopes. Mol. Immunol. 2007, 44(6):1159. 10.1016/j.molimm.2006.06.014.
    • (2007) Mol. Immunol. , vol.44 , Issue.6 , pp. 1159
    • Carmicle, S.1    Steede, N.K.2    Landry, S.J.3
  • 7
    • 79953760144 scopus 로고    scopus 로고
    • MAGE-A3 and MAGE-A4 specific CD4(+) T cells in head and neck cancer patients: detection of naturally acquired responses and identification of new epitopes
    • Cesson V., Rivals J.P., Escher A., Piotet E., Thielemans K., Posevitz V., Romero P. MAGE-A3 and MAGE-A4 specific CD4(+) T cells in head and neck cancer patients: detection of naturally acquired responses and identification of new epitopes. Cancer Immunol. Immunother. 2011, 60(1):23. 10.1007/s00262-010-0916-z.
    • (2011) Cancer Immunol. Immunother. , vol.60 , Issue.1 , pp. 23
    • Cesson, V.1    Rivals, J.P.2    Escher, A.3    Piotet, E.4    Thielemans, K.5    Posevitz, V.6    Romero, P.7
  • 8
    • 33646861187 scopus 로고    scopus 로고
    • Peptide-binding motifs for the I-Ad MHC class II molecule: alternate pH-dependent binding behavior
    • Chaves F.A., Richards K.A., Torelli A., Wedekind J., Sant A.J. Peptide-binding motifs for the I-Ad MHC class II molecule: alternate pH-dependent binding behavior. Biochemistry 2006, 45(20):6426. 10.1021/bi060194g.
    • (2006) Biochemistry , vol.45 , Issue.20 , pp. 6426
    • Chaves, F.A.1    Richards, K.A.2    Torelli, A.3    Wedekind, J.4    Sant, A.J.5
  • 9
    • 0032529386 scopus 로고    scopus 로고
    • Antigen processing of two H2-IEd-restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein
    • Chianese-Bullock K.A., Russell H.I., Moller C., Gerhard W., Monaco J.J., Eisenlohr L.C. Antigen processing of two H2-IEd-restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein. J. Immunol. 1998, 161(4):1599.
    • (1998) J. Immunol. , vol.161 , Issue.4 , pp. 1599
    • Chianese-Bullock, K.A.1    Russell, H.I.2    Moller, C.3    Gerhard, W.4    Monaco, J.J.5    Eisenlohr, L.C.6
  • 10
    • 0037305578 scopus 로고    scopus 로고
    • Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3
    • Consogno G., Manici S., Facchinetti V., Bachi A., Hammer J., Conti-Fine B.M., Protti M.P. Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3. Blood 2003, 101(3):1038. 10.1182/blood-2002-03-0933.
    • (2003) Blood , vol.101 , Issue.3 , pp. 1038
    • Consogno, G.1    Manici, S.2    Facchinetti, V.3    Bachi, A.4    Hammer, J.5    Conti-Fine, B.M.6    Protti, M.P.7
  • 11
    • 0037016774 scopus 로고    scopus 로고
    • Structural basis for helper T-cell and antibody epitope immunodominance in bacteriophage T4 Hsp10. Role of disordered loops
    • Dai G., Carmicle S., Steede N.K., Landry S.J. Structural basis for helper T-cell and antibody epitope immunodominance in bacteriophage T4 Hsp10. Role of disordered loops. J. Biol. Chem. 2002, 277(1):161. 10.1074/jbc.M102259200.
    • (2002) J. Biol. Chem. , vol.277 , Issue.1 , pp. 161
    • Dai, G.1    Carmicle, S.2    Steede, N.K.3    Landry, S.J.4
  • 12
    • 33644666732 scopus 로고    scopus 로고
    • Antigen processing by autoreactive B cells promotes determinant spreading
    • Dai Y.D., Carayanniotis G., Sercarz E. Antigen processing by autoreactive B cells promotes determinant spreading. Cell. Mol. Immunol. 2005, 2(3):169.
    • (2005) Cell. Mol. Immunol. , vol.2 , Issue.3 , pp. 169
    • Dai, Y.D.1    Carayanniotis, G.2    Sercarz, E.3
  • 13
    • 84872709815 scopus 로고    scopus 로고
    • Improving in silico prediction of epitope vaccine candidates by union and intersection of single predictors
    • Dimitrov I., Flower D.R., Doytchinova I. Improving in silico prediction of epitope vaccine candidates by union and intersection of single predictors. World J. Vaccin. 2011, 01(02):15. 10.4236/wjv.2011.12004.
    • (2011) World J. Vaccin. , vol.1 , Issue.2 , pp. 15
    • Dimitrov, I.1    Flower, D.R.2    Doytchinova, I.3
  • 14
    • 24044538903 scopus 로고    scopus 로고
    • IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
    • Dosztanyi Z., Csizmok V., Tompa P., Simon I. IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 2005, 21(16):3433. 10.1093/bioinformatics/bti541.
    • (2005) Bioinformatics , vol.21 , Issue.16 , pp. 3433
    • Dosztanyi, Z.1    Csizmok, V.2    Tompa, P.3    Simon, I.4
  • 15
    • 77950957385 scopus 로고    scopus 로고
    • Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins
    • Dosztanyi Z., Meszaros B., Simon I. Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins. Brief. Bioinform. 2010, 11(2):225. 10.1093/bib/bbp061.
    • (2010) Brief. Bioinform. , vol.11 , Issue.2 , pp. 225
    • Dosztanyi, Z.1    Meszaros, B.2    Simon, I.3
  • 17
    • 79958184746 scopus 로고    scopus 로고
    • Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes
    • Greenbaum J., Sidney J., Chung J., Brander C., Peters B., Sette A. Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes. Immunogenetics 2011, 63(6):325. 10.1007/s00251-011-0513-0.
    • (2011) Immunogenetics , vol.63 , Issue.6 , pp. 325
    • Greenbaum, J.1    Sidney, J.2    Chung, J.3    Brander, C.4    Peters, B.5    Sette, A.6
  • 18
    • 67650494289 scopus 로고    scopus 로고
    • Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design
    • Halling-Brown M., Shaban R., Frampton D., Sansom C.E., Davies M., Flower D., Moss D.S. Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design. Mol. Immunol. 2009, 46(13):2699. 10.1016/j.molimm.2009.05.027.
    • (2009) Mol. Immunol. , vol.46 , Issue.13 , pp. 2699
    • Halling-Brown, M.1    Shaban, R.2    Frampton, D.3    Sansom, C.E.4    Davies, M.5    Flower, D.6    Moss, D.S.7
  • 19
    • 0000448982 scopus 로고
    • Prediction of protein antigenic determinants from amino acid sequences
    • Hopp T.P., Woods K.R. Prediction of protein antigenic determinants from amino acid sequences. Proc. Natl. Acad. Sci. U. S. A. 1981, 78(6):3824.
    • (1981) Proc. Natl. Acad. Sci. U. S. A. , vol.78 , Issue.6 , pp. 3824
    • Hopp, T.P.1    Woods, K.R.2
  • 21
    • 0036593492 scopus 로고    scopus 로고
    • Heterogeneity of genome and proteome content in bacteria, archaea, and eukaryotes
    • Karlin S., Brocchieri L., Trent J., Blaisdell B.E., Mrazek J. Heterogeneity of genome and proteome content in bacteria, archaea, and eukaryotes. Theor. Popul. Biol. 2002, 61(4):367.
    • (2002) Theor. Popul. Biol. , vol.61 , Issue.4 , pp. 367
    • Karlin, S.1    Brocchieri, L.2    Trent, J.3    Blaisdell, B.E.4    Mrazek, J.5
  • 22
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte J., Doolittle R.F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 1982, 157(1):105.
    • (1982) J. Mol. Biol. , vol.157 , Issue.1 , pp. 105
    • Kyte, J.1    Doolittle, R.F.2
  • 23
    • 0031265431 scopus 로고    scopus 로고
    • Local protein instability predictive of helper T-cell epitopes
    • Landry S.J. Local protein instability predictive of helper T-cell epitopes. Immunol. Today 1997, 18(11):527.
    • (1997) Immunol. Today , vol.18 , Issue.11 , pp. 527
    • Landry, S.J.1
  • 24
    • 0034615793 scopus 로고    scopus 로고
    • Helper T-cell epitope immunodominance associated with structurally stable segments of hen egg lysozyme and HIV gp120
    • Landry S.J. Helper T-cell epitope immunodominance associated with structurally stable segments of hen egg lysozyme and HIV gp120. J. Theor. Biol. 2000, 203(3):189. 10.1006/jtbi.1999.1056.
    • (2000) J. Theor. Biol. , vol.203 , Issue.3 , pp. 189
    • Landry, S.J.1
  • 25
    • 42549105195 scopus 로고    scopus 로고
    • Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research
    • Lin H.H., Ray S., Tongchusak S., Reinherz E.L., Brusic V. Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research. BMC Immunol. 2008, 9:8. 10.1186/1471-2172-9-8.
    • (2008) BMC Immunol. , vol.9 , pp. 8
    • Lin, H.H.1    Ray, S.2    Tongchusak, S.3    Reinherz, E.L.4    Brusic, V.5
  • 26
    • 57649174707 scopus 로고    scopus 로고
    • Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research
    • Lin H.H., Zhang G.L., Tongchusak S., Reinherz E.L., Brusic V. Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research. BMC Bioinforma. 2008, 9(Suppl. 12):S22. 10.1186/1471-2105-9-S12-S22.
    • (2008) BMC Bioinforma. , vol.9 , Issue.SUPPL. 12
    • Lin, H.H.1    Zhang, G.L.2    Tongchusak, S.3    Reinherz, E.L.4    Brusic, V.5
  • 28
    • 79956200060 scopus 로고    scopus 로고
    • The Ising model for prediction of disordered residues from protein sequence alone
    • Lobanov M.Y., Galzitskaya O.V. The Ising model for prediction of disordered residues from protein sequence alone. Phys. Biol. 2011, 8(3):035004. 10.1088/1478-3975/8/3/035004.
    • (2011) Phys. Biol. , vol.8 , Issue.3 , pp. 035004
    • Lobanov, M.Y.1    Galzitskaya, O.V.2
  • 29
    • 2342561929 scopus 로고    scopus 로고
    • Definition of supertypes for HLA molecules using clustering of specificity matrices
    • Lund O., Nielsen M., Kesmir C., Petersen A.G., Lundegaard C., Worning P., Brunak S. Definition of supertypes for HLA molecules using clustering of specificity matrices. Immunogenetics 2004, 55(12):797. 10.1007/s00251-004-0647-4.
    • (2004) Immunogenetics , vol.55 , Issue.12 , pp. 797
    • Lund, O.1    Nielsen, M.2    Kesmir, C.3    Petersen, A.G.4    Lundegaard, C.5    Worning, P.6    Brunak, S.7
  • 30
    • 36349030248 scopus 로고    scopus 로고
    • MAGE-A3(161-175) contains an HLA-DRbeta4 restricted natural epitope poorly formed through indirect presentation by dendritic cells
    • Marturano J., Longhi R., Casorati G., Protti M.P. MAGE-A3(161-175) contains an HLA-DRbeta4 restricted natural epitope poorly formed through indirect presentation by dendritic cells. Cancer Immunol. Immunother. 2008, 57(2):207. 10.1007/s00262-007-0364-6.
    • (2008) Cancer Immunol. Immunother. , vol.57 , Issue.2 , pp. 207
    • Marturano, J.1    Longhi, R.2    Casorati, G.3    Protti, M.P.4
  • 31
    • 40449103289 scopus 로고    scopus 로고
    • Endosomal proteases influence the repertoire of MAGE-A3 epitopes recognized in vivo by CD4+ T cells
    • Marturano J., Longhi R., Russo V., Protti M.P. Endosomal proteases influence the repertoire of MAGE-A3 epitopes recognized in vivo by CD4+ T cells. Cancer Res. 2008, 68(5):1555. 10.1158/0008-5472.CAN-07-5233.
    • (2008) Cancer Res. , vol.68 , Issue.5 , pp. 1555
    • Marturano, J.1    Longhi, R.2    Russo, V.3    Protti, M.P.4
  • 32
    • 53149108231 scopus 로고    scopus 로고
    • Three dimensional structure directs T-cell epitope dominance associated with allergy
    • Melton S.J., Landry S.J. Three dimensional structure directs T-cell epitope dominance associated with allergy. Clin. Mol. Allergy 2008, 6:9. 10.1186/1476-7961-6-9.
    • (2008) Clin. Mol. Allergy , vol.6 , pp. 9
    • Melton, S.J.1    Landry, S.J.2
  • 33
    • 67049119327 scopus 로고    scopus 로고
    • Prediction of protein binding regions in disordered proteins
    • Meszaros B., Simon I., Dosztanyi Z. Prediction of protein binding regions in disordered proteins. PLoS Comput. Biol. 2009, 5(5):e1000376. 10.1371/journal.pcbi.1000376.
    • (2009) PLoS Comput. Biol. , vol.5 , Issue.5
    • Meszaros, B.1    Simon, I.2    Dosztanyi, Z.3
  • 34
    • 47049114120 scopus 로고    scopus 로고
    • Antigen structure influences helper T-cell epitope dominance in the human immune response to HIV envelope glycoprotein gp120
    • Mirano-Bascos D., Tary-Lehmann M., Landry S.J. Antigen structure influences helper T-cell epitope dominance in the human immune response to HIV envelope glycoprotein gp120. Eur. J. Immunol. 2008, 38(5):1231. 10.1002/eji.200738011.
    • (2008) Eur. J. Immunol. , vol.38 , Issue.5 , pp. 1231
    • Mirano-Bascos, D.1    Tary-Lehmann, M.2    Landry, S.J.3
  • 35
    • 0347362810 scopus 로고    scopus 로고
    • Differential processing of CD4 T-cell epitopes from the protective antigen of Bacillus anthracis
    • Musson J.A., Walker N., Flick-Smith H., Williamson E.D., Robinson J.H. Differential processing of CD4 T-cell epitopes from the protective antigen of Bacillus anthracis. J. Biol. Chem. 2003, 278(52):52425. 10.1074/jbc.M309034200.
    • (2003) J. Biol. Chem. , vol.278 , Issue.52 , pp. 52425
    • Musson, J.A.1    Walker, N.2    Flick-Smith, H.3    Williamson, E.D.4    Robinson, J.H.5
  • 36
    • 39549084433 scopus 로고    scopus 로고
    • NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence
    • Nielsen M., Lundegaard C., Blicher T., Lamberth K., Harndahl M., Justesen S., Buus S. NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence. PLoS One 2007, 2(8):e796. 10.1371/journal.pone.0000796.
    • (2007) PLoS One , vol.2 , Issue.8
    • Nielsen, M.1    Lundegaard, C.2    Blicher, T.3    Lamberth, K.4    Harndahl, M.5    Justesen, S.6    Buus, S.7
  • 37
    • 48249083459 scopus 로고    scopus 로고
    • Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
    • Nielsen M., Lundegaard C., Blicher T., Peters B., Sette A., Justesen S., Lund O. Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan. PLoS Comput. Biol. 2008, 4(7):e1000107. 10.1371/journal.pcbi.1000107.
    • (2008) PLoS Comput. Biol. , vol.4 , Issue.7
    • Nielsen, M.1    Lundegaard, C.2    Blicher, T.3    Peters, B.4    Sette, A.5    Justesen, S.6    Lund, O.7
  • 38
    • 74249104442 scopus 로고    scopus 로고
    • Assessment of disorder predictions in CASP8
    • Noivirt-Brik O., Prilusky J., Sussman J.L. Assessment of disorder predictions in CASP8. Proteins 2009, 77(Suppl. 9):210. 10.1002/prot.22586.
    • (2009) Proteins , vol.77 , Issue.SUPPL. 9 , pp. 210
    • Noivirt-Brik, O.1    Prilusky, J.2    Sussman, J.L.3
  • 39
    • 84877780179 scopus 로고    scopus 로고
    • T-cell epitope vaccine design by immunoinformatics
    • Patronov A., Doytchinova I. T-cell epitope vaccine design by immunoinformatics. Open Biol. 2013, 3(1):120139. 10.1098/rsob.120139.
    • (2013) Open Biol. , vol.3 , Issue.1 , pp. 120139
    • Patronov, A.1    Doytchinova, I.2
  • 41
    • 80054967884 scopus 로고    scopus 로고
    • A majority of the cancer/testis antigens are intrinsically disordered proteins
    • Rajagopalan K., Mooney S.M., Parekh N., Getzenberg R.H., Kulkarni P. A majority of the cancer/testis antigens are intrinsically disordered proteins. J. Cell. Biochem. 2011, 112(11):3256. 10.1002/jcb.23252.
    • (2011) J. Cell. Biochem. , vol.112 , Issue.11 , pp. 3256
    • Rajagopalan, K.1    Mooney, S.M.2    Parekh, N.3    Getzenberg, R.H.4    Kulkarni, P.5
  • 42
    • 84900856927 scopus 로고    scopus 로고
    • Knowledge based threading approach to model the MHC-binders to MHC class I alleles in Hepatitis E Virus: a clue for epitope-based vaccine design
    • Rathi B., Sarangi A., Naik S. Knowledge based threading approach to model the MHC-binders to MHC class I alleles in Hepatitis E Virus: a clue for epitope-based vaccine design. Internet J. Med. Inform. 2010, 5(2). 10.5580/22cf.
    • (2010) Internet J. Med. Inform. , vol.5 , Issue.2
    • Rathi, B.1    Sarangi, A.2    Naik, S.3
  • 43
    • 23144443082 scopus 로고    scopus 로고
    • PEPVAC: a web server for multi-epitope vaccine development based on the prediction of supertypic MHC ligands
    • Web Server issue
    • Reche P.A., Reinherz E.L. PEPVAC: a web server for multi-epitope vaccine development based on the prediction of supertypic MHC ligands. Nucleic Acids Res. 2005, 33(Web Server issue):W138. 10.1093/nar/gki357.
    • (2005) Nucleic Acids Res. , vol.33
    • Reche, P.A.1    Reinherz, E.L.2
  • 45
    • 22544482556 scopus 로고    scopus 로고
    • The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes
    • Sant A.J., Chaves F.A., Jenks S.A., Richards K.A., Menges P., Weaver J.M., Lazarski C.A. The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes. Immunol. Rev. 2005, 207:261. 10.1111/j.0105-2896.2005.00307.x.
    • (2005) Immunol. Rev. , vol.207 , pp. 261
    • Sant, A.J.1    Chaves, F.A.2    Jenks, S.A.3    Richards, K.A.4    Menges, P.5    Weaver, J.M.6    Lazarski, C.A.7
  • 46
    • 0036813331 scopus 로고    scopus 로고
    • Cancer/testis antigens: an expanding family of targets for cancer immunotherapy
    • Scanlan M.J., Gure A.O., Jungbluth A.A., Old L.J., Chen Y.T. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol. Rev. 2002, 188:22.
    • (2002) Immunol. Rev. , vol.188 , pp. 22
    • Scanlan, M.J.1    Gure, A.O.2    Jungbluth, A.A.3    Old, L.J.4    Chen, Y.T.5
  • 47
    • 84885949386 scopus 로고    scopus 로고
    • Improved disorder prediction by combination of orthogonal approaches
    • Schlessinger A., Punta M., Yachdav G., Kajan L., Rost B. Improved disorder prediction by combination of orthogonal approaches. PLoS One 2009, 4(2):e4433. 10.1371/journal.pone.0004433.
    • (2009) PLoS One , vol.4 , Issue.2
    • Schlessinger, A.1    Punta, M.2    Yachdav, G.3    Kajan, L.4    Rost, B.5
  • 48
    • 2942627626 scopus 로고    scopus 로고
    • Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
    • Seong S.Y., Matzinger P. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat. Rev. Immunol. 2004, 4(6):469. 10.1038/nri1372.
    • (2004) Nat. Rev. Immunol. , vol.4 , Issue.6 , pp. 469
    • Seong, S.Y.1    Matzinger, P.2
  • 49
    • 0041402836 scopus 로고    scopus 로고
    • Epitope-based vaccines: an update on epitope identification, vaccine design and delivery
    • Sette A., Fikes J. Epitope-based vaccines: an update on epitope identification, vaccine design and delivery. Curr. Opin. Immunol. 2003, 15(4):461.
    • (2003) Curr. Opin. Immunol. , vol.15 , Issue.4 , pp. 461
    • Sette, A.1    Fikes, J.2
  • 50
    • 39649122106 scopus 로고    scopus 로고
    • HLA class I supertypes: a revised and updated classification
    • Sidney J., Peters B., Frahm N., Brander C., Sette A. HLA class I supertypes: a revised and updated classification. BMC Immunol. 2008, 9:1. 10.1186/1471-2172-9-1.
    • (2008) BMC Immunol. , vol.9 , pp. 1
    • Sidney, J.1    Peters, B.2    Frahm, N.3    Brander, C.4    Sette, A.5
  • 53
    • 79960659875 scopus 로고    scopus 로고
    • Context-dependent resistance to proteolysis of intrinsically disordered proteins
    • Suskiewicz M.J., Sussman J.L., Silman I., Shaul Y. Context-dependent resistance to proteolysis of intrinsically disordered proteins. Protein Sci. 2011, 20(8):1285. 10.1002/pro.657.
    • (2011) Protein Sci. , vol.20 , Issue.8 , pp. 1285
    • Suskiewicz, M.J.1    Sussman, J.L.2    Silman, I.3    Shaul, Y.4
  • 55
    • 77949328500 scopus 로고    scopus 로고
    • The mysterious unfoldome: structureless, underappreciated, yet vital part of any given proteome
    • Uversky V.N. The mysterious unfoldome: structureless, underappreciated, yet vital part of any given proteome. J. Biomed. Biotechnol. 2010, 2010:568068. 10.1155/2010/568068.
    • (2010) J. Biomed. Biotechnol. , vol.2010 , pp. 568068
    • Uversky, V.N.1
  • 56
    • 79955580331 scopus 로고    scopus 로고
    • Intrinsically disordered proteins may escape unwanted interactions via functional misfolding
    • Uversky V.N. Intrinsically disordered proteins may escape unwanted interactions via functional misfolding. Biochim. Biophys. Acta 2011, 1814(5):693.
    • (2011) Biochim. Biophys. Acta , vol.1814 , Issue.5 , pp. 693
    • Uversky, V.N.1
  • 57
    • 77949916296 scopus 로고    scopus 로고
    • Understanding protein non-folding
    • Uversky V.N., Dunker A.K. Understanding protein non-folding. Biochim. Biophys. Acta 2010, 1804(6):1231. 10.1016/j.bbapap.2010.01.017.
    • (2010) Biochim. Biophys. Acta , vol.1804 , Issue.6 , pp. 1231
    • Uversky, V.N.1    Dunker, A.K.2
  • 58
    • 0034669882 scopus 로고    scopus 로고
    • Why are "natively unfolded" proteins unstructured under physiologic conditions?
    • Uversky V.N., Gillespie J.R., Fink A.L. Why are "natively unfolded" proteins unstructured under physiologic conditions?. Proteins 2000, 41(3):415.
    • (2000) Proteins , vol.41 , Issue.3 , pp. 415
    • Uversky, V.N.1    Gillespie, J.R.2    Fink, A.L.3
  • 60
    • 72449206256 scopus 로고    scopus 로고
    • Understanding the focused CD4 T cell response to antigen and pathogenic organisms
    • Weaver J.M., Sant A.J. Understanding the focused CD4 T cell response to antigen and pathogenic organisms. Immunol. Res. 2009, 45(2-3):123. 10.1007/s12026-009-8095-8.
    • (2009) Immunol. Res. , vol.45 , Issue.2-3 , pp. 123
    • Weaver, J.M.1    Sant, A.J.2
  • 61
    • 51549100883 scopus 로고    scopus 로고
    • Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design
    • Weaver J.M., Lazarski C.A., Richards K.A., Chaves F.A., Jenks S.A., Menges P.R., Sant A.J. Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design. J. Immunol. 2008, 181(5):3039.
    • (2008) J. Immunol. , vol.181 , Issue.5 , pp. 3039
    • Weaver, J.M.1    Lazarski, C.A.2    Richards, K.A.3    Chaves, F.A.4    Jenks, S.A.5    Menges, P.R.6    Sant, A.J.7
  • 62
    • 64049090391 scopus 로고    scopus 로고
    • An introduction to epitope prediction methods and software
    • Yang X., Yu X. An introduction to epitope prediction methods and software. Rev. Med. Virol. 2009, 19(2):77. 10.1002/rmv.602.
    • (2009) Rev. Med. Virol. , vol.19 , Issue.2 , pp. 77
    • Yang, X.1    Yu, X.2
  • 63
    • 81255134467 scopus 로고    scopus 로고
    • MULTIPRED2: a computational system for large-scale identification of peptides predicted to bind to HLA supertypes and alleles
    • Zhang G.L., DeLuca D.S., Keskin D.B., Chitkushev L., Zlateva T., Lund O., Brusic V. MULTIPRED2: a computational system for large-scale identification of peptides predicted to bind to HLA supertypes and alleles. J. Immunol. Methods 2011, 374(1-2):53. 10.1016/j.jim.2010.11.009.
    • (2011) J. Immunol. Methods , vol.374 , Issue.1-2 , pp. 53
    • Zhang, G.L.1    DeLuca, D.S.2    Keskin, D.B.3    Chitkushev, L.4    Zlateva, T.5    Lund, O.6    Brusic, V.7


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