Pharmaceutical optimization of lipid-based dosage forms for the improvement of taste-masking, chemical stability and solubilizing capacity of phenobarbital

Drug Development and Industrial Pharmacy

Volumn 40, Issue 6, 2014, Pages 783-792

  Monteagudo, Ezequiel ^a   Langenheim, Mariana ^a   Salerno, Claudia ^a   Buontempo, Fabián ^a,b   Bregni, Carlos ^a   Carlucci, Adriana ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

Author keywords

Biopharmaceutical advantages; Chemical degradation; Electronic tongue; Microemulsion; SEDDS

Indexed keywords

ALCOHOL; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; GLYCEROL; LABRASOL; MACROGOL 400; MIGLYOL; MYRISTIC ACID ISOPROPYL ESTER; OCTANOIN; PHENOBARBITAL; PROPYLENE GLYCOL; SUCRALOSE; SURFACTANT; ANTICONVULSIVE AGENT; DRUG CARRIER; EMULSION; LIPID; OIL;

ARTICLE; BANANA; BITTER TASTE; CAPSULE FILLING; CONDUCTANCE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG SOLUBILITY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VIVO STUDY; MASKING; MICROEMULSION; PHYSICAL CHEMISTRY; STRAWBERRY; TASTE; TASTE MASKING; VISCOSITY; BIOLOGICAL MODEL; CHEMISTRY; DRUG FORMULATION; EMULSION; FLOW KINETICS; PROCEDURES; SOLUBILITY; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY;

ANTICONVULSANTS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; EMULSIONS; LIPIDS; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; OILS; PHENOBARBITAL; PHYSICOCHEMICAL PHENOMENA; RHEOLOGY; SOLUBILITY; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS; TASTE;

EID: 84900857753     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.787536     Document Type: Article

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