Antitumor effects of the flavone chalcone: Inhibition of invasion and migration through the FAK/JNK signaling pathway in human gastric adenocarcinoma AGS cells

Molecular and Cellular Biochemistry

Volumn 391, Issue 1-2, 2014, Pages 47-58

  Lin, Su Hsuan ^a   Shih, Yuan Wei ^b  

^a KAOHSIUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^b CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

Author keywords

Chalcone; FAK; Invasion; JNK1 2; Migration; MMP 2; MMP 9

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIMETASTATIC AGENT; CHALCONE; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 9; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE 1; ANTINEOPLASTIC AGENT; DNA; FLAVONE; FLAVONE DERIVATIVE; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; PROTEIN BINDING; UROKINASE;

ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STOMACH ADENOCARCINOMA; WOUND HEALING; ADENOCARCINOMA; CELL DEATH; CELL MEMBRANE; CELL MOTION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH TUMOR; TUMOR CELL LINE; TUMOR INVASION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL DEATH; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CELL-MATRIX JUNCTIONS; CHALCONE; DNA; FLAVONES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; I-KAPPA B PROTEINS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; PROTEOLYSIS; STOMACH NEOPLASMS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84900835063     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-1986-6     Document Type: Article

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