Amphetamine-induced dopamine release and neurocognitive function in treatment-naive adults with ADHD

Neuropsychopharmacology

Volumn 39, Issue 6, 2014, Pages 1498-1507

  Cherkasova, Mariya V ^a   Faridi, Nazlie ^a   Casey, Kevin F ^a   O'Driscoll, Gillian A ^a   Hechtman, Lily ^a   Joober, Ridha ^b   Baker, Glen B ^c   Palmer, Jennifer ^a   Dagher, Alain ^a   Leyton, Marco ^a,d   Benkelfat, Chawki ^a  

^a MCGILL UNIVERSITY   (Canada)

^b DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

^d Douglas Institute ^*  (Canada)

Author keywords

ADHD; d amphetamine; dopamine; executive functions; PET

Indexed keywords

DEXAMPHETAMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; RACLOPRIDE C 11; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE UPTAKE INHIBITOR; RACLOPRIDE;

ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DOPAMINERGIC SYSTEM; DOUBLE BLIND PROCEDURE; HUMAN; IMPULSIVENESS; MALE; PERFORMANCE; PET SCANNER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BLOOD; BRAIN MAPPING; EXECUTIVE FUNCTION; INHIBITION (PSYCHOLOGY); METABOLISM; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; SCINTISCANNING; TASK PERFORMANCE;

ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN MAPPING; CORPUS STRIATUM; DEXTROAMPHETAMINE; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; EXECUTIVE FUNCTION; HUMANS; INHIBITION (PSYCHOLOGY); MALE; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; RACLOPRIDE; TASK PERFORMANCE AND ANALYSIS;

EID: 84900826082     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.349     Document Type: Article

References (52)

1. Alexander GE, Crutcher MD, DeLong MR (1990). Basal gangliathalamocortical circuits: parallel substrates for motor, oculomotor, 'prefrontal' and 'limbic' functions. Prog Brain Res 85: 119-146.
2. Allman A-A, Benkelfat C, Durand F, Sibon I, Dagher A, Leyton M et al (2010). Effect of d-amphetamine on inhibition and motor planning as a function of baseline performance. Psychopharmacology 211: 423-433.
3. Aron AR, Dowson JH, Sahakian BJ, Robbins TW (2003). Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry 54: 1465-1468. (Pubitemid 37522172)
4. Asghar SJ, Baker GB, Rauw GA, Silverstone PH (2002). A rapid method of determining amphetamine in plasma samples using pentafluorobenzenesulfonyl chloride and electron-capture gas chromatography. J Pharmacol Toxicol Methods 46: 111-115. (Pubitemid 34681000)
5. Aston J, Gunn R, Worsley K, Ma Y, Evans AC, Dagher A (2000). A statistical method for the analysis of positron emission tomopgraphy neuroreceptor ligand data. Neuroimage 12: 245-256.
6. Aston JA, Cunningham VJ, Asselin MC, Hammers A, Evans AC, Gunn RN (2002). Positron emission tomography partial volume correction: estimation and algorithms. J Cereb Blood Flow Metab 22: 1019-1034. (Pubitemid 34831609)
7. Beck AT, Steer RA (1993). Manual for the Revised Beck Depression Inventory. Psychological Corporation: San Antonio, TX.
8. Boileau I, Dagher A, Leyton M, Gunn RN, Baker GB, Diksic M et al (2006). Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men. Arch Gen Psychiatry 63: 1386-1395. (Pubitemid 44878522)
9. Buckholtz JW, Treadway MT, Cowan RL, Woodward ND, Li R, Ansari MS et al (2010). Dopaminergic network differences in human impulsivity. Science 329: 532.
10. Casey KF, Benkelfat C, Cherkasova MV, Baker GB, Dagher A, Leyton M (2013). Reduced dopamine response to amphetamine in subjects at ultra-high risk for addiction. Biol Psychiatry e-pub ahead of print 16 October 2013 (doi:10.1016/j.biopsych.2013. 08.033).
11. Collins DL, Neelin P, Peters TM, Evans AC (1994). Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 18: 192-205. (Pubitemid 24100002)
12. Conners CK, Erhart D, Sparrow E (1999). Conners' Adult ADHD Rating Scales. Technical Manual. Multi-Health Systems: New York.
13. Costes N, Dagher A, Larcher K, Evans AC, Collins DL, Reilhac A (2009). Motion correction of multi-frame PET data in neuroreceptor mapping: Simulation based validation. Neuroimage 47: 1496-1505.
14. Daberkow DP, Brown HD, Bunner KD, Kraniotis SA, Doellman MA, Ragozzino ME et al (2013). Amphetamine paradoxically augments exocytotic dopamine release and phasic dopamine signals. J Neurosci 33: 452-463.
15. Dagher A (2012). Addiction as aberrant learning-evidence from Parkinson's disease. Addiction 107: 248-250.
16. Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Laane K et al (2007). Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science 315: 1267-1270. (Pubitemid 46364262)
17. Dickstein SG, Bannon K, Castellanos FX, Milham MP (2006). The neural correlates of attention deficit hyperactivity disorder: an ALE meta-analysis. J Child Psychol Psychiatry 47: 1051-1062. (Pubitemid 44642434)
18. Dixon W, Yuen K (1974). Trimming and winsorization: a review. Stat Papers 15: 157-170.
19. Ettinger U, Kumari V, Crawford TJ, Davis RE, Sharma T, Corr PJ (2003). Reliability of smooth pursuit, fixation, and saccadic eye movements. Psychophysiology 40: 1-9.
20. Faraone SV, Mick E (2010). Molecular genetics of attention deficit hyperactivity disorder. Psychiatr Clin North Am 33: 159-180.
21. First MB, Spitzer RL, Gibbon M, Williams JBW (1996). Structured Clinical Interview for DSM-IV Axis I Disorders. Biometrics Research Department, New York State Psychiatric Institute New York.
22. Grace AA (2001). Psychostimulant actions on dopamine and limbic system function: relevance to the pathophysiology and treatment of ADHD. In: Solanto MArnsten AFCastellanos FX (eds) Stimulant Drugs and ADHD: Basic and Clinical Neuroscience. Oxford University Press: New York, pp 134-157.
23. Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ (1997). Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 6: 279-287. (Pubitemid 28018717)
24. Haber SN (2010). Convergence of limbic, cognitive, and motor cortico-striatal circuits with dopamine pathways in the primate brain. In: Iversen LIversen SDDunnett SBBjorklund A (eds) Dopamine Handbook. Oxford University Press: Oxford, pp 38-48.
25. Hallett PE (1978). Primary and secondary saccades to goals defined by instructions. Vision Res 18: 1279-1296. (Pubitemid 9044240)
26. Hikosaka O, Takikawa Y, Kawagoe R (2000). Role of the basal ganglia in the control of purposive saccadic eye movements. Physiol Rev 80: 953-978. (Pubitemid 30452008)
27. Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN et al (2007). Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab 27: 1533-1539. (Pubitemid 47301451)
28. Kegeles LS, Zea-Ponce Y, Abi-Dargham A, Rodenhiser J, Wang T, Weiss R et al (1999). Stability of [123I]IBZM SPECT measurement of amphetamine-induced striatal dopamine release in humans. Synapse 31: 302-308. (Pubitemid 29070292)
29. Lammertsma AA, Hume SP (1996). Simplified reference tissue model for PET receptor studies. Neuroimage 4(3 Pt 1): 153-158.
30. Laruelle M (2000). Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J Cereb Blood Flow Metab 20: 423-451. (Pubitemid 30164887)
31. Leyton M, aan het Rot M, Booij L, Baker GB, Young SN, Benkelfat C (2007). Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion. J Psychiatry Neurosci 32: 129-136. (Pubitemid 46597959)
32. Logan GD, Cowan WB, Davis KA (1984). On the ability to inhibit simple and choice reaction time responses: a model and a method. J Exp Psychol Hum Percept Perform 10: 276-291.
33. Lou HC, Rosa P, Pryds O, Karrebaek H, Lunding J, Cumming P et al (2004). ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow. Dev Med Child Neurol 46: 179-183. (Pubitemid 38263453)
34. Martinez D, Slifstein M, Broft A, Mawlawi O, Hwang DR, Huang Y et al (2003). Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: amphetamineinduced dopamine release in the functional subdivisions of the striatum. J Cereb Blood Flow Metab 23: 285-300. (Pubitemid 36307573)
35. Munro CA, McCaul ME, Wong DF, Oswald LM, Zhou Y, Brasic J et al (2006). Sex differences in striatal dopamine release in healthy adults. Biol Psychiatry 59: 966-974.
36. Nigg JT (2005). Neuropsychologic theory and findings in attention-deficit/hyperactivity disorder: the sate of the field and salient challenges for the coming decade. Biol Psychiatry 57: 1424.
37. Pilgrim BM, Meyers JE, Bayless J, Whetstone MM (1999). Validity of the Ward seven-subtest WAIS-III short form in a neuropsychological population. Appl Neuropsychol 6: 243-246. (Pubitemid 30030306)
38. Pohjalainen T, Rinne JO, Någren K, Syvälahti E, Hietala J (1998). Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo. Am J Psychiatry 155: 768-773. (Pubitemid 28252655)
39. Reynolds CR, Willson VL, Clark PL (1983). A four-test short-form of the WAIS-R for clinical screening. Clin Neuropsychol 5: 111-116. (Pubitemid 14131119)
40. Riccardi P, Zald D, Li R, Park S, Ansari MS, Dawant B et al (2006). Sex differences in amphetamine-induced displacement of [18F]fallypride in striatal and extrastriatal regions: a PET study. Am J Psychiatry 163: 1639-1641. (Pubitemid 44465768)
41. Rosa-Neto P, Lou HC, Cumming P, Pryds O, Karrebaek H, Lunding J et al (2005). Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder. Neuroimage 25: 868.
42. Sled JG, Zijdenbos AP, Evans AC (1998). A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17: 87-97. (Pubitemid 128742012)
43. Sontag TA, Tucha O, Walitza S, Lange KW (2010). Animal models of attention deficit/hyperactivity disorder (ADHD): a critical review. Atten Defic Hyperact Disord 2: 1-20.
44. Spencer T, Biederman J, Madras B, Faraone S, Dougherty D, Bonab A et al (2005). In vivo neuroreceptor imaging in attention-deficit/hyperactivity disorder: a focus on the dopamine transporter. Biol Psychiatry 57: 1293-1300. (Pubitemid 40798548)
45. Spencer T, Biederman J, Wilens T, Harding M, O'Donnell D, Griffin S (1996). Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle. J Am Acad Child Adoles Psychiatry 35: 409-432. (Pubitemid 126418605)
46. Spencer TJ, Biederman J, Faraone SV, Madras BK, Bonab AA, Dougherty DD et al (2013). Functional genomics of attentiondeficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biol Psychiatry 74: 84-89.
47. Tziortzi AC, Haber SN, Searle GE, Tsoumpas C, Long CJ, Shotbolt P et al (2013). Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography. Cereb Cortex e-pub ahead of print, 2 January 2013 (doi:10.1093/cercor/bhs397).
48. Volkow ND, Wang G-J, Newcorn J, Fowler JS, Telang F, Solanto MV et al (2007a). Brain dopamine transporter levels in treatment and drug naïve adults with ADHD. Neuroimage 34: 1182.
49. Volkow ND, Wang G-J, Newcorn J, Telang F, Solanto MV, Fowler JS et al (2007b). Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 64: 932-940. (Pubitemid 47230617)
50. Volkow ND, Wang GJ, Fowler JS, Ding YS (2005). Imaging the effects of methylphenidate on brain dopamine: new model on its therapeutic actions for attention-deficit/hyperactivity disorder. Biol Psychiatry 57: 1410-1415. (Pubitemid 40798562)
51. Volkow ND, Wang GJ, Kollins SH, Wigal TL, Newcorn JH, Telang F et al (2009). Evaluating dopamine reward pathway in ADHD: clinical implications. JAMA 302: 1084-1091.
52. Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, Evans AC (1996). A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 4: 58-73. (Pubitemid 26195721)