Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Mauris, Jerome ^a   Mantelli, Flavio ^a,e   Woodward, Ashley M ^a   Cao, Ziyhi ^b   Bertozzi, Carolyn R ^c,d   Panjwani, Noorjahan ^b   Godula, Kamil ^d,f   Argüeso, Pablo ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e IRCCS FONDAZIONE BIETTI   (Italy)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLOBIOSE; GALECTIN 3; GLYCOPOLYMER; LACTOSE; POLYMER; ROSE BENGAL; UNCLASSIFIED DRUG; GLYCOCONJUGATE; MUCIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOSYNTHESIS; CELL MEMBRANE; CONTROLLED STUDY; CORNEA EPITHELIUM; DELETION MUTANT; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; GLYCOCALYX; GLYCOCALYX BARRIER FUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PERMEABILITY; POLYMERIZATION; PROTEIN BINDING; PROTEIN DOMAIN; ANIMAL; CELL CULTURE; CHEMISTRY; CORNEA; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL;

MUS;

ANIMALS; BIOLOGICAL TRANSPORT; CELLOBIOSE; CELLS, CULTURED; CORNEA; EPITHELIAL CELLS; GALECTIN 3; GLYCOCALYX; GLYCOCONJUGATES; HUMANS; LACTOSE; MICE; MICE, KNOCKOUT; MUCINS; PERMEABILITY; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; ROSE BENGAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84900823404     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072304     Document Type: Article

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