Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: Role for tethered mucins as barriers to lumenal infection

Journal of Virology

Volumn 78, Issue 24, 2004, Pages 13755-13768

  Stonebraker, Jaclyn R ^a   Wagner, Danielle ^a   Lefensty, Robert W ^a   Burns, Kimberlie ^a   Gendler, Sandra J ^c   Bergelson, Jeffrey M ^d   Boucher, Richard C ^a   O'Neal, Wanda K ^a   Pickles, Raymond J ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; GLYCOSYLPHOSPHATIDYLINOSITOL; MUCIN; MUCIN 1; RECEPTOR;

APICAL MEMBRANE; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE DELETION; GENE EXPRESSION; GENE TRANSFER; GLYCOCALYX; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RESPIRATORY EPITHELIUM; TRANSGENIC MOUSE;

ADENOVIRIDAE; ANIMALS; CA-15-3 ANTIGEN; CELL POLARITY; CYSTIC FIBROSIS; EPITHELIAL CELLS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLYCOCALYX; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, VIRUS; RESPIRATORY SYSTEM;

EID: 10044229609     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.24.13755-13768.2004     Document Type: Article

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