Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 2327-2333

  Ding, Shu Min ^a,b,c   Zhang, Zhen Hai ^a,c   Song, Jie ^a,c   Cheng, Xu Dong ^a,c   Jiang, Jun ^a,c   Jia, Xiao Bin ^a,c  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CHANGZHOU UNIVERSITY   (China)

^c Key laboratory of New Drug Delivery system of chinese Materia Medica Jiangsu Provincial academy of chinese Medicine   (China)

Author keywords

Apigenin; Carbon nanopowder; Dissolution; Oral bioavailability; Solid dispersions

Indexed keywords

APIGETRIN; CARBON; CARBON NANOPOWDER; DRUG CARRIER; NANOMATERIAL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APIGENIN; CARBON NANOTUBE; EMULSION; NANOCAPSULE; POWDER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG SAFETY; DRUG SOLUBILITY; GASTROINTESTINAL TOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; SCANNING ELECTRON MICROSCOPY; SOLID DISPERSION; TOXICITY TESTING; X RAY DIFFRACTION; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DIFFUSION; DRUG POTENTIATION; EMULSION; GASTROINTESTINAL ABSORPTION; METABOLIC CLEARANCE RATE; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PHYSIOLOGY; POWDER; SOLUBILITY; SPRAGUE DAWLEY RAT; SYNTHESIS; TOXICITY; ULTRASTRUCTURE;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; APIGENIN; BIOLOGICAL AVAILABILITY; DIFFUSION; DRUG SYNERGISM; EMULSIONS; MALE; METABOLIC CLEARANCE RATE; NANOCAPSULES; NANOTUBES, CARBON; ORAL MUCOSAL ABSORPTION; PARTICLE SIZE; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY;

EID: 84900819986     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S60938     Document Type: Article

References (31)

1. Wu DG, Yu P, Li J W, et al. Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells. Toxicol Lett. 2014;224(1):157-164.
2. Chunhua L, Donglan L, Xiuqiong F, et al. Apigenin up-regulates trans-gelin and inhibits invasion and migration of colorectal cancer through decreased phosphorylation of AKT. J Nutr Biochem. 2013;24(10): 1766-1775.
3. Wei H, Tye L, Bresnick E, Birt DF. Inhibitory effect of apigenin, a plant favonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice. Cancer Res. 1990;50(3):499-502.
4. Hossain MM, Banik NL, Ray SK. N-Myc knockdown and apigenin treatment controlled growth of malignant neuroblastoma cells having N-Myc amplifcation. Gene. 2013;529(1):27-36.
5. Way TD, Kao MC, Lin JK. Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. J Biol Chem. 2004;279(6):4479-4489.
6. Block MJ. Chemcycolpedia. American Chemical Society. Washington, 2000:106-107.
7. Zhang J, Liu D, Huang Y, Gao Y, Qian S. Biopharmaceutics classif-cation and intestinal absorption study of apigenin. Int J Pharm. 2012; 436(1-2):311-317.
8. Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm. 2000;50(1): 47-60.
9. Vo CL, Park C, Lee BJ. Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs. Eur J Pharm Biopharm. 2013;85(3 Pt B):799-813.
10. Kim MS, Kim JS, Park HJ, Cho WK, Cha KH, Hwang SJ. Enhanced bioavailability of sirolimus via preparation of solid dispersion nano-particles using a supercritical antisolvent process. Int J Nanomedicine. 2011;6:2997-3009.
11. Kim SA, Kim S W, Choi HK, Han HK. Enhanced systemic exposure of saquinavir via the concomitant use of curcumin-loaded solid dispersion in rats. Eur J Pharm Sci. 2013;49(5):800-804.
12. Vasconcelos T, Sarmento B, Costa P. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. Drug Discov Today. 2007;12(23-24):1068-1075.
13. Arias MJ, Gines JM, Moyano JR, Rabasco AM. The application of solid dispersion technique with D-mannitol to the improvement in oral absorption of triamterene. J Drug Target. 1994;2(1):45-51.
14. Dai WG, Dong LC, Song YQ. Nanosizing of a drug/carrageenan complex to increase solubility and dissolution rate. Int J Pharm. 5, 2007; 342(1-2):201-207.
15. Jiang YR, Zhang ZH, Liu QY, Hu S Y, Chen XY, Jia XB. Preparation, characterization, and in vivo evaluation of tanshinone IIA solid dispersions with silica nanoparticles. Int J Nanomedicine. 2018: 2285-2293.
16. El-Sayed Y, Bandosz TJ. Role of surface oxygen groups in incorporation of nitrogen to activated carbons via ethylmethylamine adsorption. Langmuir. 2005;21(4):1282-1289.
17. Trifonov A, Herkendell K, Tel-Vered R, Yehezkeli O, Woerner M, Willner I. Enzyme-capped relay-functionalized mesoporous carbon nanoparticles: effective bioelectrocatalytic matrices for sensing and biofuel cell applications. ACS Nano. 2013;7(12): 11358-11368.
18. Zhu Y, Zhang X, Zhu J, et al. Cytotoxicity of phenol red in toxic-ity assays for carbon nanoparticles. Int J Mol Sci. 26, 2012;13(10): 12336-12348.
19. Wu L, Luderer M, Yang X, et al. Surface passivation of carbon nanoparticles with branched macromolecules infuences near infrared bioimaging. Theranostics. 2013;3(9):677-686.
20. Oh WK, Yoon H, Jang J. Size control of magnetic carbon nanoparticles for drug delivery. Biomaterials. 2010;31(6):1342-1348.
21. Xie J, Lee S, Chen X. Nanoparticle-based theranostic agents. Adv Drug Deliv Rev. 2010;62(11):1064-1079.
22. Muthukumar T, Prabhavathi S, Chamundeeswari M, Sastry T P. Bio-modifed carbon nanoparticles loaded with methotrexate possible carrier for anticancer drug delivery. Mater Sci Eng C Mater Biol Appl. 2014;36:14-19.
23. Lau BW, Yan A, Weissman BS, et al. Biocompatible, hydrophilic, supramolecular carbon nanopowders for cell delivery. Lung Cancer. 2006;54(S1):S55-S56.
24. Parihar S, Sharon M, Sharon M. Carbon nanomaterial shows drug delivery promise: Part 1 - Selection of carbon nanomaterial and drug loading. Synth React Inorg Met-Org. 2006;36:107-113.
25. Shi NQ, Lei YS, Song LM, Yao J, Zhang XB, Wang XL. Impact of amorphous and semicrystalline polymers on the dissolution and crystallization inhibition of pioglitazone solid dispersions. Powder Technol. 2013;247:211-221.
26. Zhang Y, Wang H, Li C, et al. A Novel Three-Dimensional Large-Pore Mesoporous Carbon Matrix as a Potential Nanovehicle for the Fast Release of the Poorly Water-soluble Drug, Celecoxib. Pharm Res. 2014;31(4):1059-1070.
27. Zhao P, Wang L, Sun C, et al. Uniform mesoporous carbon as a carrier for poorly water soluble drug and its cytotoxicity study. Eur J Pharm Biopharm. 2012;80(3):535-543.
28. Zhang J, Huang Y, Liu D, Gao Y, Qian S. Preparation of apigenin nanocrystals using supercritical antisolvent process for dissolution and bioavailability enhancement. Eur J Pharm Sci. 2013;48(4-5): 740-747.
29. Marasini N, Tran TH, Poudel BK, et al. Fabrication and evaluation of pH-modulated solid dispersion for telmisartan by spray-drying technique. Int J Pharm. 2013;441(1-2):424-432.
30. Ford JL, Rubinstein MH. Formulation and ageing of tablets prepared from indomethacin-polyethylene glycol 6000 solid dispersions. Pharm Acta Helv. 1980;55(1):1-7.
31. Guedes FL, de Oliveira BG, Hernandes MZ, et al. Solid dispersions of imidazolidinedione by PEG and PVP polymers with potential antischistosomal activities. AAPS PharmSciTech. 2011;12(1): 401-410.