Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells

Stem Cell Research and Therapy

Volumn 5, Issue 2, 2014, Pages

  Kadari, Asifiqbal ^a   Lu, Min ^b   Li, Ming ^b,c   Sekaran, Thileepan ^a   Thummer, Rajkumar P ^a   Guyette, Naomi ^b   Chu, Vi ^b   Edenhofer, Frank ^a,d  

^a UNIVERSITY OF BONN   (Germany)

^b MILLIPORE CORPORATION   (United States)

^c Irvine Pharmaceutical Services Inc   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CRE RECOMBINASE; INTEGRASE;

ADULT; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; GENE CASSETTE; GENETIC ASSOCIATION; GENETIC TRANSDUCTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MALE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TISSUE ENGINEERING; TRANSGENE; CASE REPORT; CYTOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; LENTIVIRINAE; NUCLEAR REPROGRAMMING; PHYSIOLOGY; YOUNG ADULT;

CELL DIFFERENTIATION; CELLULAR REPROGRAMMING; GENE EXPRESSION; GENETIC VECTORS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INTEGRASES; LENTIVIRUS; MALE; MUTAGENESIS, INSERTIONAL; TRANSDUCTION, GENETIC; TRANSGENES; YOUNG ADULT;

EID: 84900812586     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt435     Document Type: Article

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