Antioxidative properties of ethyl acetate fraction of Globimetula braunii in normal albino rats

Journal of Biological Sciences

Volumn 9, Issue 5, 2009, Pages 470-475

  Okpuzor, J ^a   Ogbunugafor, H ^b   Karecm, G K ^a  

^a UNIVERSITY OF LAGOS   (Nigeria)

^b NNAMDI AZIKIWE UNIVERSITY   (Nigeria)

Author keywords

Antioxidant enzymes; HPLC; Naringin and apigenin; Reactive oxygen species

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIOXIDANT; APIGENIN; AURANTIIN; CATALASE; FREE RADICAL; GLOBIMETULA BRAUNII EXTRACT; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; METHANOL; PHENOL DERIVATIVE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; ELUTION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; FRACTIONATION; GLOBIMETULA BRAUNII; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MEDICINAL PLANT; NIGERIA; NONHUMAN; RAT; RAT STRAIN; SWISS ALBINO RAT; TRIACYLGLYCEROL BLOOD LEVEL;

GLOBIMETULA; RATTUS;

EID: 67650649810     PISSN: 17273048     EISSN: 18125719     Source Type: Journal    
DOI: 10.3923/jbs.2009.470.475     Document Type: Article

References (32)

1. Aruoma, O.I., 2003. Methodological considerations for characterizing potential antioxidant actions of bioactive components in food plants. Mut. Res., 523: 9-20.
2. Buhler, D. and C. Miranda, 2000. Antioxidant Action of Flavonoids. Micronutrients Information Center, Linus Pauling Institute, London.
3. Burkill, H.M., 1985. The Useful Plants of West Tropical Africa. Vol. 3, Ithaka Harbors Incorporation, New York, ISBN: 10: 1900347660, pp: 369.
4. Choi, E. and J. Hwang, 2005. Effects of some medicinal plants on plasma antioxidant system and. lipid levels in rats. Phytother. Res., 19: 382-386.
5. Darlington, L.G. and T.W. Stone, 2001. Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. Br. J. Nutr., 85: 251-269.
6. Dongmo, A.B., A. Kamanyi, G. Dzikouk, C.B. Nkeh and P.V. Tan et al., 2003. Anti-inflammatory and analgestic properties of the, stem bark extract of M. ciliata (Rubiaceae) Aubrev and Pellegr. J. Ethnopharmacol., 83:17-21.
7. Finkel, T. and N.J. Holbrook, 2000. Oxidants, oxidative stress and the biology of aging. Nature, 408: 239-247.
8. Gaetani, G.F., S. Galiano, L. Canepa, AM. Ferraris and H.N. Kirkman, 1989. Catalase and glutathione peroxidase are equally effective in detoxification of hydrogen peroxide in human erythrocytes. Blood, 73: 334-339.
9. Gao, F., J.R. Koenizer, J.M. Tobolewski,D. Jiang, J. Liiang, P.W. Noble and T.D. Qury, 2008. Exracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronan J. Biol. Chem., 283: 6058-6066.
10. Goyal, V., S. Chetal and S. S. Nainawatee, 1986. Alterations in Rhizobium trifolii catalase under water stress. J. Folia Microbiologica, 31: 164-166.
11. Koditschek, L.K. and W.W. Umbreit, 1969. Enzymatic calorimetric test for triglycerides with lipid clearing factor (LCF). J. Bacteriol., 68:1063-1068.
12. Landmesser, U. and H. Drexler, 2002. Towards understanding superoxide dismutase regulation in atherosclerosis. Art. Thro. Vasc. Biol.1, 22: 1367-1370.
13. Niehaus, Jr. W.G. and B. Samuelson, 1968. Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur. Biochem., 6:126-130.
14. Nwanjo, H.U., 2007. Free radicals scavenging potential of the aqueous extract of Viscum album (Mistletoe) leaves in diabetic wistar rats hepatocytes. Internet J. Nutr. Wellness
15. Ogbunugafor, H.A., V.I. Okochi, J. Okpuzor, S. Esue and T. Adedayo, 2007. Mitragyna ciliata and its trypanocidal activity. Afr. J. Biotechnol., 6: 2310-2313.
16. Osawa, T., 1999. Protective role of dietary polyphenols in oxidative stress. Mechanism Ageing Dev., 111: 133-139.
17. Pereira, R.M.S., N.E.D. Andrades, N. Paulino, A.C.H.F. Sawaya and M.N. Eberlin et al., 2007. Synthesis and characterization of a metal complex containing naningin and Cu and its antioxidantive, antimicrobial and anti-inflammatory and tumor cell cytotoxicity. Molecules, 12: 1352-1366.
18. Repetto, M.G. and S.F. Llesuy, 2002. Antioxidant properties of natural compounds used in popular medicine for gastric ulcers. Braz. J. Med. Biol. Res., 35: 523-534.
19. Semiz, A. and A. Son, 2007. Antioxidant and chemoprotective properties of Momordica charantia L. (bitter melon) fruit extract. Afr. J. Biotechnol., 6: 273-277.
20. Shah, P.K., S. Kaul, J. Nilsson and B. Cercek, 2001. Exploiting the vascular protective effect of high-density lipoprotein and its apolipoproteins. Circulation, 104: 2498-2502.
21. Shull, S., N.H. Heintz, M. Periasamy, M. Manohar, Y.M. Janssen, J.P. Marsh and B.T. Mossman, 1991. Differential regulation of antioxidant enzymes in response oxidants. J. Biol. Chem., 266: 24399-24403.
22. Silva, M.M.A., MR. Santos, G. Caroco, R. Rocha, G. Justino and L. Mira, 2002. Structure-antioxidant activity relationships of some flavonoids: A reexamination. Free Radical Res., 36: 1219-1227.
23. Singh Devaraj, U and I. Jialal, 2005. Vitamin E, oxidative stress and inflammation. Ann. Rev. Nutr., 25: 151-174.
24. Sofidiya, M.O., O.A. Odukoya, O.B. Familoni and S.I. Inya-Agha, 2006. Free radical scavenging activity of some Nigerian medicinal plant extracts. Pak. J. Biol. Sci., 9: 1438-1441.
25. Surh, Y.Z. and L.R. Fergusson, 2003. Dietary and medicinal antimutagens and anticarcinogens: Molecular mechanisms and chemopreventive effects of selected dietary and medicinal phenolic substances. Mut. Res. Fundamental Mol. Mechanisms Mutagenesis, 523-524: 1-8.
26. Tappel, A.L., 1978. Glutathione peroxidase and hydroperoxides. Methods Enzymol., 52: 506-513.
27. Usoh, I.F., E.J. Akpan, E.O. Etim and E.O. Farombi, 2005. Antioxidant actions of dried flower extracts of Hibiscus sabdariffa L. on sodium arsenite-induced oxidative stress in rats. Pak. J. Nutr., 4: 135-141.
28. Wan, J. and D. Diaz-Sanchez, 2007. Antioxidant enzyme induction: A new protective approach against the adverse effects of diesel exhaust. particles. Inhalation Toxicol., 19: 1771-182.
29. Wu, J., Y. Tung, S. Warig, L. Shyur, Y. Kwo and S. Chang, 2005. Phenolic antioxidant from the heartwood of Acacia confusa. J. Agric. Food Chem., 53: 5917-5921.
30. Yeh, C-T. and G.C. Yen, 2006. Induction of hepatic antioxidant enzymes by phenolic acids in rats is accompanied by increased levels of multidrug resistance-associated protein 3 mRNA Expression. J. Nutr., 136: 11-15.
31. Yesilada, E. and E. Kupeli, 2002. Berberis crataegina DC. exhibits potent anti-inflammatory analgesic and febrifuge effects in mice and rats. J. Ethnopharmacol., 79: 237-248.
32. Zelko, I., T. Mariani and R. Folz, 2002. Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2) and EC-SOD (SOD3) gene structures, evolution and expression. Free Radical Med. Biol., 33: 337-349.