Hepatic and hematologic effects of fractions of Globimetula Braunii in normal albino rats

EXCLI Journal

Volumn 8, Issue , 2009, Pages 182-189

  Okpuzor, J ^a   Ogbunugafor, H A ^b   Kareem, G K ^a  

^a UNIVERSITY OF LAGOS   (Nigeria)

^b NNAMDI AZIKIWE UNIVERSITY   (Nigeria)

Author keywords

Fractions; Globimetula braunii; Hematologic; Hepatic; Medicinal plant; Toxic

Indexed keywords

EID: 70349921880     PISSN: None     EISSN: 16112156     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Adjanohoun FJ, Ake Assi L, Floret JJ, Guinko S, Koumare M, Ahyi AMR, et al. Contribution of the ethnobotanicals and flora in Mali to traditional medicine. Paris: Pharmacopia, 1985.
2. Al-Ghaithi F, Mandouh R, El-Ridi MR, Adeghate E, Amiri MH. Biochemical effect of citrullus colocynthis in normal and dia-betic rats. Mol Cell Biochem 2004;261: 143-9.
3. Burkhill HM. Useful plants of West Africa. 2nd ed., Vol. 1: Families A-D. Royal Bo-tanic Gardens, Kew, 1985. ISBN 094764301X
4. th ed. 1995
5. De Silva T. Medicinal plants for forest conservation and health care: industrial utilization of medicinal plants in developing countries. Global Initiative for Traditional Systems (gifts) of Health. Food and Agricultural Organization of the United Nations 1997;11:34-44.
6. Dongmo AB, Kamanyi A, Dzikouk G, Nkeh CB, Tan PV, Nguelefack T, Nole T, Bopelet M, Wagner H. Anti-inflammatory and analgesic properties of the stem bark extract of Mitragyna ciliata (Rubiaceae) Aubrév. & Pellegr. J Ethnopharmacol 2003;84:17-21.
7. Gathumbi PK, Nwangi JW, Njiro SM, Mugera GM. Biochemical and haemato-logical changes in rats administered an aqueous extract of Prunis africana stem bark at various dosage levels. Ondersteport. J Vet Res 2000;67:123-8.
8. Iweala EEJ, Okeke CU. Comparative study of the hypoglycemic and biochemical ef-fects of Catharanthus roseus (Linn) g. Apocynaceae (Madagascar periwinkle) and chloropropamide (diabenese) on Alloxan-induced diabetic rats. Biokemistri 2005;17: 149-56.
9. Iwu MM. Handbook of African medicinal plants. Boca Raton, FL: CRC Press, 1993; pp 4-10.
10. th ed. Philadelphia, PA: Lea & Febinger, 1986; pp 567-72.
11. Jendrassik L, Grof P. In-vitro determination of total and direct bilirubin in serum. Bio-chemistry 1938;297:81-8.
12. Nwinuka NM, Monamu MO, Nwiloh BI. Effect of aqueous extract of Mangifera Indica L (Mango) stem bark on haematologi-cal parameters of normal albino rats. Pak J Nutr 2008;7:663-6.
13. Okpuzor J, Ogbunugafor HA, Kareem GK. Antioxidative properties of ethyl acetate fractions of Globumentulla braunii in normal albino rats. J Biol Sci 2009;9:470-5.
14. Oluyemi KA, Omotuyi IO, Jimoh OA, Saalu CL, Josiah SJ. Erythropoetic and an-tiobesity effects of Garcinia cambogia (bit-ter kola) in Wistar rats. Biotechnol Appl Biochem 2007;46:69-72.
15. Ouedraogo S, Ranaivo HR, Ndiaye M, Kabore ZI, Guissou PI, Bucher B, et al. Cardiovascular properties of aqueous extract from Mitragyna inermis (wild). J Eth-nopharmacol 2004;93:345-50.
16. Phillipson JD Wright CW. Can ethnophar-macology contribute to the development of antimalarial agents? J Ethnopharmacol 1991;32:155-65.
17. Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28: 56-63.
18. Satyapal SU, Kadam VJ, Ghosh R. Hepato-protective activity of Livobond, a poly-herbal formulation against CCl4 induced hepatotoxicity in rats. Int J Pharmacol 2008;4:472-6.
19. Scott Luper ND. A review of plants used in the treatment of liver disease. Pt. 1. Altern Med Rev 1998;3:410-21.
20. Shahraki MR, Arab MR, Marimo KE, Palan MJ. The effect of Teucrium Polium (Cal-poureh) on liver function, serum lipids and glucose in diabetic male rats. Iran Biomed J 2007;11:65-8.
21. th ed. New York: Hackwell Science, 2002; pp 110-23.
22. Spinella M. The importance of pharmacological synergy in phycoactive herbal medi-cines - Herbal synergy review. Altern Med Rev 2002;7:130-7.
23. th ed. Philadephia, PA: Saunders, 2000; pp 744-5, 788-9.
24. Traore F, Gasquet M, Laget M, Guiraud H, Giorgio CD, Azas N, Doumbo O, Timon-David P. Toxicity and genotoxicity of anti-malarial alkaloid rich extracts derived from Mitragyma inermis O. Kuntze and Nuclea latifolia. Phytother Res 2000;4:608-11.
25. Yesilada E, Kupeli E. Berberis crataegina exhibits potent anti-inflammatory analgesic and febrifuge effects in mice and rats. J Ethnopharmacol 2002;79:237-48.