Dissociable effects of antipsychotics on ketamine-induced changes in regional oxygenation and inter-regional coherence of low frequency oxygen fluctuations in the rat

Neuropsychopharmacology

Volumn 39, Issue 7, 2014, Pages 1635-1644

  Li, Jennifer ^a   Ishiwari, Keita ^a,b   Conway, Michael W ^a   Francois, Jennifer ^a   Huxter, John ^a   Lowry, John P ^b   Schwarz, Adam J ^a   Tricklebank, Mark ^a   Gilmour, Gary ^a  

^a ELI LILLY AND COMPANY   (United States)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Antipsychotics; Brain tissue oxygen; Coherence; Constant potential amperometry; Functional connectivity; Ketamine

Indexed keywords

CLOZAPINE; HALOPERIDOL; KETAMINE; OXYGEN; AMINO ACID RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT;

AMPEROMETRY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BOLD SIGNAL; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG POTENTIATION; HYPEROXIA; MALE; NONHUMAN; OXYGEN TISSUE LEVEL; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; TISSUE OXYGENATION; WAKEFULNESS; ANALYSIS OF VARIANCE; ANIMAL; AREA UNDER THE CURVE; BRAIN; CHEMICALLY INDUCED; DISEASE MODEL; DISSOCIATIVE DISORDERS; DRUG EFFECTS; METABOLISM; TISSUE DISTRIBUTION; TOXICITY;

ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; AREA UNDER CURVE; BRAIN; CLOZAPINE; DISEASE MODELS, ANIMAL; DISSOCIATIVE DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; HALOPERIDOL; KETAMINE; MALE; OXYGEN; RATS; TISSUE DISTRIBUTION;

EID: 84900561728     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.10     Document Type: Article

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