-
1
-
-
79953805710
-
An evidence-based systematic review on medical therapies for inflammatory bowel disease
-
Talley NJ, Abreu MT, Achkar JP etal. An evidence-based systematic review on medical therapies for inflammatory bowel disease. Am. J. Gastroenterol. 2011; 106: S2-S25.
-
(2011)
Am. J. Gastroenterol.
, vol.106
-
-
Talley, N.J.1
Abreu, M.T.2
Achkar, J.P.3
-
2
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ etal. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group. N. Engl. J. Med. 1997; 337: 1029-1035.
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
van Deventer, S.J.3
-
3
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
-
Hanauer SB, Feagan BG, Lichtenstein GR etal. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002; 359: 1541-1549.
-
(2002)
Lancet
, vol.359
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
-
4
-
-
0036732707
-
Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease
-
Vermeire S, Louis E, Carbonez A etal. Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease. Am. J. Gastroenterol. 2002; 97: 2357-2363.
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 2357-2363
-
-
Vermeire, S.1
Louis, E.2
Carbonez, A.3
-
5
-
-
0037560163
-
An analysis of factors influencing short-term and sustained response to infliximab treatment for Crohn's disease
-
Arnott ID, McNeill G, Satsangi J. An analysis of factors influencing short-term and sustained response to infliximab treatment for Crohn's disease. Aliment. Pharmacol. Ther. 2003; 17: 1451-1457.
-
(2003)
Aliment. Pharmacol. Ther.
, vol.17
, pp. 1451-1457
-
-
Arnott, I.D.1
McNeill, G.2
Satsangi, J.3
-
6
-
-
0035988896
-
A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism
-
Louis E, Vermeire S, Rutgeerts P etal. A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism. Scand. J. Gastroenterol. 2002; 37: 818-824.
-
(2002)
Scand. J. Gastroenterol.
, vol.37
, pp. 818-824
-
-
Louis, E.1
Vermeire, S.2
Rutgeerts, P.3
-
7
-
-
78249240373
-
Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease
-
Di Sabatino A, Biancheri P, Piconese S etal. Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease. Inflamm. Bowel Dis. 2010; 16: 1891-1897.
-
(2010)
Inflamm. Bowel Dis.
, vol.16
, pp. 1891-1897
-
-
Di Sabatino, A.1
Biancheri, P.2
Piconese, S.3
-
8
-
-
26244456815
-
Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease
-
Hlavaty T, Pierik M, Henckaerts L etal. Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease. Aliment. Pharmacol. Ther. 2005; 22: 613-626.
-
(2005)
Aliment. Pharmacol. Ther.
, vol.22
, pp. 613-626
-
-
Hlavaty, T.1
Pierik, M.2
Henckaerts, L.3
-
9
-
-
12144287977
-
Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease
-
Louis E, El Ghoul Z, Vermeire S etal. Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease. Aliment. Pharmacol. Ther. 2004; 19: 511-519.
-
(2004)
Aliment. Pharmacol. Ther.
, vol.19
, pp. 511-519
-
-
Louis, E.1
El Ghoul, Z.2
Vermeire, S.3
-
10
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
11
-
-
53549097349
-
MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death
-
Schickel R, Boyerinas B, Park SM, Peter ME. MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene 2008; 27: 5959-5974.
-
(2008)
Oncogene
, vol.27
, pp. 5959-5974
-
-
Schickel, R.1
Boyerinas, B.2
Park, S.M.3
Peter, M.E.4
-
12
-
-
43449102192
-
Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
-
Lawrie CH, Gal S, Dunlop HM etal. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br. J. Haematol. 2008; 141: 672-675.
-
(2008)
Br. J. Haematol.
, vol.141
, pp. 672-675
-
-
Lawrie, C.H.1
Gal, S.2
Dunlop, H.M.3
-
13
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
Mitchell PS, Parkin RK, Kroh EM etal. Circulating microRNAs as stable blood-based markers for cancer detection. Proc. Natl Acad. Sci. U.S.A. 2008; 105: 10513-10518.
-
(2008)
Proc. Natl Acad. Sci. U.S.A.
, vol.105
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
-
14
-
-
53349177819
-
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
-
Chen X, Ba Y, Ma L etal. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008; 18: 997-1006.
-
(2008)
Cell Res.
, vol.18
, pp. 997-1006
-
-
Chen, X.1
Ba, Y.2
Ma, L.3
-
15
-
-
52349083651
-
Serum microRNAs are promising novel biomarkers
-
Gilad S, Meiri E, Yogev Y etal. Serum microRNAs are promising novel biomarkers. PLoS One 2008; 3: e3148.
-
(2008)
PLoS One
, vol.3
-
-
Gilad, S.1
Meiri, E.2
Yogev, Y.3
-
16
-
-
65849322883
-
Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients
-
Tanaka M, Oikawa K, Takanashi M etal. Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients. PLoS One 2009; 4: e5532.
-
(2009)
PLoS One
, vol.4
-
-
Tanaka, M.1
Oikawa, K.2
Takanashi, M.3
-
17
-
-
66049112674
-
Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
-
Ng EK, Chong WW, Jin H etal. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009; 58: 1375-1381.
-
(2009)
Gut
, vol.58
, pp. 1375-1381
-
-
Ng, E.K.1
Chong, W.W.2
Jin, H.3
-
18
-
-
72949112451
-
Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction
-
Ai J, Zhang R, Li Y etal. Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem. Biophys. Res. Commun. 2010; 391: 73-77.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 73-77
-
-
Ai, J.1
Zhang, R.2
Li, Y.3
-
19
-
-
77952086523
-
Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
-
Murata K, Yoshitomi H, Tanida S etal. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res. Ther. 2010; 12: R86.
-
(2010)
Arthritis Res. Ther.
, vol.12
-
-
Murata, K.1
Yoshitomi, H.2
Tanida, S.3
-
20
-
-
79955675453
-
Serum and urinary free microRNA level in patients with systemic lupus erythematosus
-
Wang G, Tam LS, Li EK etal. Serum and urinary free microRNA level in patients with systemic lupus erythematosus. Lupus 2011; 20: 493-500.
-
(2011)
Lupus
, vol.20
, pp. 493-500
-
-
Wang, G.1
Tam, L.S.2
Li, E.K.3
-
21
-
-
55249119513
-
MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha
-
Wu F, Zikusoka M, Trindade A etal. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 2008; 135: 1624-1635.e24.
-
(2008)
Gastroenterology
, vol.135
-
-
Wu, F.1
Zikusoka, M.2
Trindade, A.3
-
22
-
-
78649231641
-
Identification of microRNAs associated with ileal and colonic Crohn's disease
-
Wu F, Zhang S, Dassopoulos T etal. Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm. Bowel Dis. 2010; 16: 1729-1738.
-
(2010)
Inflamm. Bowel Dis.
, vol.16
, pp. 1729-1738
-
-
Wu, F.1
Zhang, S.2
Dassopoulos, T.3
-
23
-
-
77951579490
-
Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis
-
Takagi T, Naito Y, Mizushima K etal. Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis. J. Gastroenterol. Hepatol. 2010; 25: S129-S133.
-
(2010)
J. Gastroenterol. Hepatol.
, vol.25
-
-
Takagi, T.1
Naito, Y.2
Mizushima, K.3
-
24
-
-
78049340862
-
Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease
-
Fasseu M, Tréton X, Guichard C etal. Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PLoS One 2010; 5: e13160.
-
(2010)
PLoS One
, vol.5
-
-
Fasseu, M.1
Tréton, X.2
Guichard, C.3
-
25
-
-
79959852640
-
Circulating microRNA is a biomarker of pediatric Crohn disease
-
Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, Friedman JR. Circulating microRNA is a biomarker of pediatric Crohn disease. J. Pediatr. Gastroenterol. Nutr. 2011; 53: 26-33.
-
(2011)
J. Pediatr. Gastroenterol. Nutr.
, vol.53
, pp. 26-33
-
-
Zahm, A.M.1
Thayu, M.2
Hand, N.J.3
Horner, A.4
Leonard, M.B.5
Friedman, J.R.6
-
26
-
-
0033785374
-
Crohn's disease in Japan: diagnostic criteria and epidemiology
-
Yao T, Matsui T, Hiwatashi N. Crohn's disease in Japan: diagnostic criteria and epidemiology. Dis. Colon Rectum 2000; 43: S85-93.
-
(2000)
Dis. Colon Rectum
, vol.43
-
-
Yao, T.1
Matsui, T.2
Hiwatashi, N.3
-
27
-
-
52949091534
-
The let-7 family of microRNAs
-
Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol. 2008; 18: 505-516.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 505-516
-
-
Roush, S.1
Slack, F.J.2
-
28
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J etal. RAS is regulated by the let-7 microRNA family. Cell 2005; 120: 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
29
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007; 315: 1576-1579.
-
(2007)
Science
, vol.315
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
30
-
-
79952282998
-
Let-7/miR-98 regulate Fas and Fas-mediated apoptosis
-
Wang S, Tang Y, Cui H etal. Let-7/miR-98 regulate Fas and Fas-mediated apoptosis. Genes Immun. 2011; 12: 149-154.
-
(2011)
Genes Immun.
, vol.12
, pp. 149-154
-
-
Wang, S.1
Tang, Y.2
Cui, H.3
-
31
-
-
79955763550
-
A let-7/Fas double-negative feedback loop regulates human colon carcinoma cells sensitivity to Fas-related apoptosis
-
Geng L, Zhu B, Dai BH etal. A let-7/Fas double-negative feedback loop regulates human colon carcinoma cells sensitivity to Fas-related apoptosis. Biochem. Biophys. Res. Commun. 2011; 408: 494-499.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 494-499
-
-
Geng, L.1
Zhu, B.2
Dai, B.H.3
-
32
-
-
77951620660
-
The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma
-
Shimizu S, Takehara T, Hikita H etal. The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J. Hepatol. 2010; 52: 698-704.
-
(2010)
J. Hepatol.
, vol.52
, pp. 698-704
-
-
Shimizu, S.1
Takehara, T.2
Hikita, H.3
-
33
-
-
0034957289
-
Decreased Bax expression by mucosal T cells favours resistance to apoptosis in Crohn's disease
-
Itoh J, de La Motte C, Strong SA, Levine AD, Fiocchi C. Decreased Bax expression by mucosal T cells favours resistance to apoptosis in Crohn's disease. Gut 2001; 49: 35-41.
-
(2001)
Gut
, vol.49
, pp. 35-41
-
-
Itoh, J.1
de La Motte, C.2
Strong, S.A.3
Levine, A.D.4
Fiocchi, C.5
-
34
-
-
0033565302
-
Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance
-
Ina K, Itoh J, Fukushima K etal. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. J. Immunol. 1999; 163: 1081-1090.
-
(1999)
J. Immunol.
, vol.163
, pp. 1081-1090
-
-
Ina, K.1
Itoh, J.2
Fukushima, K.3
-
35
-
-
34147211616
-
Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease
-
Van den Brande JM, Koehler TC, Zelinkova Z etal. Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease. Gut 2007; 56: 509-517.
-
(2007)
Gut
, vol.56
, pp. 509-517
-
-
Van den Brande, J.M.1
Koehler, T.C.2
Zelinkova, Z.3
-
36
-
-
0346461662
-
Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease
-
Di Sabatino A, Ciccocioppo R, Cinque B etal. Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease. Gut 2004; 53: 70-77.
-
(2004)
Gut
, vol.53
, pp. 70-77
-
-
Di Sabatino, A.1
Ciccocioppo, R.2
Cinque, B.3
-
37
-
-
0036151047
-
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
-
ten Hove T, van Montfrans C, Peppelenbosch MP, van Deventer SJ. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002; 50: 206-211.
-
(2002)
Gut
, vol.50
, pp. 206-211
-
-
ten Hove, T.1
van Montfrans, C.2
Peppelenbosch, M.P.3
van Deventer, S.J.4
-
38
-
-
0034754480
-
Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway
-
Lügering A, Schmidt M, Lügering N, Pauels HG, Domschke W, Kucharzik T. Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway. Gastroenterology 2001; 121: 1145-1157.
-
(2001)
Gastroenterology
, vol.121
, pp. 1145-1157
-
-
Lügering, A.1
Schmidt, M.2
Lügering, N.3
Pauels, H.G.4
Domschke, W.5
Kucharzik, T.6
-
39
-
-
14944382276
-
Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha
-
Mitoma H, Horiuchi T, Hatta N etal. Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha. Gastroenterology 2005; 128: 376-392.
-
(2005)
Gastroenterology
, vol.128
, pp. 376-392
-
-
Mitoma, H.1
Horiuchi, T.2
Hatta, N.3
-
40
-
-
84856894610
-
Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production
-
Zwiers A, Kraal L, van de Pouw Kraan TC, Wurdinger T, Bouma G, Kraal G. Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production. J. Immunol. 2012; 188: 1573-1577.
-
(2012)
J. Immunol.
, vol.188
, pp. 1573-1577
-
-
Zwiers, A.1
Kraal, L.2
van de Pouw Kraan, T.C.3
Wurdinger, T.4
Bouma, G.5
Kraal, G.6
-
41
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR etal. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
42
-
-
84871701834
-
Ustekinumab induction and maintenance therapy in refractory Crohn's disease
-
Sandborn WJ, Gasink C, Gao LL etal. Ustekinumab induction and maintenance therapy in refractory Crohn's disease. N. Engl. J. Med. 2012; 367: 1519-1528.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1519-1528
-
-
Sandborn, W.J.1
Gasink, C.2
Gao, L.L.3
-
43
-
-
84863242402
-
miR-200b is involved in intestinal fibrosis of Crohn's disease
-
Chen Y, Ge W, Xu L etal. miR-200b is involved in intestinal fibrosis of Crohn's disease. Int. J. Mol. Med. 2012; 29: 601-606.
-
(2012)
Int. J. Mol. Med.
, vol.29
, pp. 601-606
-
-
Chen, Y.1
Ge, W.2
Xu, L.3
-
44
-
-
78650119948
-
Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease
-
Wu F, Guo NJ, Tian H etal. Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm. Bowel Dis. 2011; 17: 241-250.
-
(2011)
Inflamm. Bowel Dis.
, vol.17
, pp. 241-250
-
-
Wu, F.1
Guo, N.J.2
Tian, H.3
-
45
-
-
84865768344
-
Circulating microRNA in inflammatory bowel disease
-
Paraskevi A, Theodoropoulos G, Papaconstantinou I, Mantzaris G, Nikiteas N, Gazouli M. Circulating microRNA in inflammatory bowel disease. J Crohns Colitis. 2012; 6: 900-904.
-
(2012)
J Crohns Colitis.
, vol.6
, pp. 900-904
-
-
Paraskevi, A.1
Theodoropoulos, G.2
Papaconstantinou, I.3
Mantzaris, G.4
Nikiteas, N.5
Gazouli, M.6
-
46
-
-
53049083199
-
Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease
-
Van Limbergen J, Russell RK, Drummond HE etal. Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease. Gastroenterology 2008; 135: 1114-1122.
-
(2008)
Gastroenterology
, vol.135
, pp. 1114-1122
-
-
Van Limbergen, J.1
Russell, R.K.2
Drummond, H.E.3
-
47
-
-
53049110159
-
Natural history of pediatric Crohn's disease: a population-based cohort study
-
Vernier-Massouille G, Balde M, Salleron J etal. Natural history of pediatric Crohn's disease: a population-based cohort study. Gastroenterology 2008; 135: 1106-1113.
-
(2008)
Gastroenterology
, vol.135
, pp. 1106-1113
-
-
Vernier-Massouille, G.1
Balde, M.2
Salleron, J.3
|