Effects of emodin and irbesartan on ventricular fibrosis in Goldblatt hypertensive rats

Pharmazie

Volumn 69, Issue 5, 2014, Pages 374-378

  Chen, Qiang ^a   Pang, Lingpin ^b   Huang, Shian ^b   Lei, Wei ^b   Huang, Dangsheng ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; COLLAGEN; EMODIN; GELATINASE A; HYDROXYPROLINE; IRBESARTAN; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG EFFECT; DRUG MECHANISM; HEART LEFT VENTRICLE MASS; HEART MUSCLE FIBROSIS; LEFT VENTRICULAR MASS INDEX; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RENOVASCULAR HYPERTENSION; SYSTOLIC BLOOD PRESSURE;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CARDIOMYOPATHIES; COLLAGEN; ECHOCARDIOGRAPHY; EMODIN; ENZYME INHIBITORS; FIBROSIS; HEART VENTRICLES; HYDROXYPROLINE; HYPERTENSION, RENOVASCULAR; HYPERTROPHY, LEFT VENTRICULAR; MALE; MATRIX METALLOPROTEINASE 2; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLES;

EID: 84900531909     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2014.3816     Document Type: Article

References (39)

1. Barlucchi L, Leri A, Dostal DE, Fiordaliso F, Tada H, Hintze TH, Kajstura J, Nadal-Ginard B, Anversa P (2001) Canine ventricular myocytes possess a renin-angiotensin system that is upregulated with heart failure. Circ Res 8: 298-304. (Pubitemid 32173753)
2. Bergman MR, Teerlink JR, Mahimkar R, Li L, Zhu BQ, Nguyen A, Dahi S, Karliner JS, Lovett DH (2007) Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am J Physiol-Heart C 292: H1847-1860. (Pubitemid 46572408)
3. Chen C, Liang Z, Chen Q, Li ZG (2012) Irbesartan and emodin on myocardial remodeling in Goldblatt hypertensive rats. J Cardiovasc Pharm 60: 375-380.
4. Chiu PY, Mak DH, Poon MK, Ko KM (2002) In vivo antioxidant action of a lignanenriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. Planta Med 68: 951-956. (Pubitemid 35448986)
5. Gu J, Zhang X, Fei Z, Wen A, Qin S, Yi S, Chen Y, Li X (2000) Rhubarb extracts in treating complications of severe cerebral injury. Chinese Med J-Peking 113: 529-531.
6. Guan S, Fox K, Mitchell NLG (1992) Angiotensin and angiotensin converting enzyme tissue levels in two-kidney, one-clip hypertensive rats. Hypertension 20: 763-767.
7. Heo SK, Yun HJ, Park WH, Park SD (2008) Emodin inhibits TNF-alpha-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis. J Cell Biochem 105: 70-80.
8. Huang Q, Lu G, Shen HM, Chung MC, Ong CN (2007) Anti-cancer properties of anthraquinones from rhubarb. Med Res Rev 27: 609-630. (Pubitemid 47282446)
9. Jiménez E, Pérez de La Blanca E, Urso L, González I, Salas J, Montiel M (2009) Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells. Biochem Bioph Res Co 380: 769-774.
10. Ju M, Chen K, Chang B, Gu H (2012) UVA1 irradiation inhibits fibroblast proliferation and alleviates pathological changes of scleroderma in a mouse model. J Biomed Res 26: 135-142.
11. Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z (2011) Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress. Circulation 124: 2094-2105.
12. Kassiri Z, Defamie V, Hariri M, Oudit GY, Anthwal S, Dawood F, Liu P, Khokha R (2009) Simultaneous TGF beta-TNF activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in TIMP-3 deficient heart. J Biol Chem 284: 29893-29904.
13. Kuo YC, Meng HC, Tsai WJ (2001) Regulation of cell proliferation, inflammatory cytokine production and calcium mobilization in primary humanT lymphocytes by emodin from Polygonum hypoleucum Ohwi. Inflamm Res 50: 73-82.
14. Li L, Fan D, Wang C, Wang JY, Cui XB, Wu D, Zhou Y, Wu LL (2011) Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts. Cardiovasc Res 91: 80-89.
15. Li L, Yan J, Hu K, Gu J, Wang JJ, Deng XL, Li H, Jing X, Li ZY, Ye QF, Ouyang DS (2012) Protective effects of Eucommia lignans against hypertensive renal injury by inhibiting expression of aldose reductase. J Ethnopharmacol 139: 454-461.
16. Liu G, Hitomi H, Hosomi N, Lei B, Pelisch N, Nakano D, Kiyomoto H, Ma H, Nishiyama A (2010) Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells. Hypertens Res 33: 1250-1257.
17. Lu MC, Hsieh MT, Wu CR, Cheng HY, Hsieh CC, Lin YT, Peng WH (2007) Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats. J Ethnopharmacol 112: 552-556.
18. Ma J, Zheng L, Deng T, Li CL, He YS, Li HJ, Li P (2013) Stilbene glucoside inhibits the glucuronidation of emodin in rats through the down-regulation of UDP-glucuronosyltransferases 1A8: application to a drug-drug interaction study in Radix Polygoni Multiflori. J Ethnopharmacol 147: 335-340.
19. Mirotsou M, Jayawardena TM, Schmeckpeper J, Gnecchi M, Dzau VJ (2011) Paracrine mechanisms of stem cell reparative and regenerative actions in the heart. J Mol Cell Cardiol 50: 280-289.
20. Rizzi E, Ceron CS, Guimaraes DA (2013) Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-β in renovascular hypertension-induced cardiac hypertrophy. Exp Mol Pathol 94: 1-9.
21. Sato H, Ishizawa F, Hirayama H, Hishinuma T, Mizugaki M (1992) Extra-weak chemiluminescence of drugs. XIV. Quenching effects of anthraquinones on the extra-weak chemiluminescence from lipid peroxidation in rat brain homogenates. Yakugaku Zasshi 112: 199-202.
22. Saygili E, Rana OR, Meyer C, Gemein C, Andrzejewski MG, Ludwig A, Weber C, Schotten U, Krüttgen A, Weis J, Schwinger RH, Mischke K, Rassaf T, Kelm M, Schauerte P (2009) The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes. Basic Res Cardiol 104: 435-438.
23. Striker GE, Praddaude F, Alcazar O, CousinsSW, Marin-Castaño ME(2008) Regulation of angiotensin II receptors and extracellular matrix turnover in human retinal pigment epithelium: role of angiotensin II. Am J Physiol-Cell Ph 295: C1633-1646.
24. Switzer BR, SummerGK(1971) Improved method for hydroxyproline analysis in tissue hydrolyzates. Anal Biochem 39: 487-491.
25. Symvoulakis EK, Kyrmizakis DE, Drivas EI, Bizakis J, Velegrakis GA, Lionis C (2007) Angiotensin-converting enzyme inhibitor (ACE-I)-and angiotensin receptor blocker (ARB)-related angioedema: a neglected issue in daily practice in Greece. Eur J Gen Pract 13: 239-241. (Pubitemid 351372180)
26. Takai S, Kirimura K, Jin D, Muramatsu M, Yoshikawa K, Mino Y, Miyazaki M. (2005) Significance of angiotensin II receptor blocker lipophilicities and their protective effect against vascular remodeling. Hypertens Res 28: 593-600. (Pubitemid 41387290)
27. Visse R, Nagase H (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92: 827-839. (Pubitemid 36542523)
28. Wang CH, Gao ZQ, Ye B, Cai JT, Xie CG, Qian KD, Du Q (2007) Effect of emodin on pancreatic fibrosis in rats.World J Gastroenterol 13: 378-382. (Pubitemid 46178971)
29. Weber KT, Sun Y, Bhattacharya SK, Ahokas RA, Gerling IC (2013) Myofibroblast-mediated mechanisms of pathological remodelling of the heart. Nat Rev Cardiol 10: 15-26.
30. Wynn TA (2008) Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210.
31. Xiao PG, Xing ST, Wang LW (1993) Immunological aspects of Chinese medicinal plants as antiageing drugs. J Ethnopharmacol 38: 167-175.
32. Xiong HR, Luo J, HouW, Xiao H, Yang ZQ (2011) The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo. J Ethnopharmacol 133: 718-723.
33. Ye M, Han J, Chen H, Zheng J, Guo D (2007) Analysis of phenolic compounds in rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry. J Am Soc Mass Spectrom 18: 82-91. (Pubitemid 46038166)
34. Yim H, Lee YH, Lee CH, Lee SK (1999) Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum selectively inhibits the activity of casein kinase II as a competitive inhibitor. Planta Med. 6: 9-13. (Pubitemid 29077420)
35. ZhanYT, Liu B, Li DG, Bi CS (2004) Mechanism of emodin for anti-fibrosis of liver. Chinese J Hepatol 12: 245-246.
36. Zhang Z, Zhuang QQ, Mei MZ (1983) Effect of some drugs on plasma and liver lipoprotein lipase activities and plasma cholesterol levels in rats. Acta Pharmacol Sin 18: 468-471.
37. Zhao ZZ (2004) An Illustrated Chinese Material Medica in HongKong. Chung Hwa Book Co., Ltd., Hong Kong, pp. 307-308.
38. Zheng HZ, Dong ZH, Se J (1997) Modern research and application of traditional Chinese medicine. J Fermentation Bioeng 84: 378-381.
39. Zile MR, Desantis SM, Baicu CF, Stroud RE, Thompson SB, McClure CD, Mehurg SM, Spinale FG (2011) Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure. Circ-Heart Fail 4: 246-256.