-
1
-
-
0032529631
-
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers
-
Chen LC, Manjeshwar S, Lu Y, et al., The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers. Cancer Res 1998; 58: 3677-3683.
-
(1998)
Cancer Res
, vol.58
, pp. 3677-3683
-
-
Chen, L.C.1
Manjeshwar, S.2
Lu, Y.3
-
2
-
-
0033008771
-
Comparative genomic hybridization of squamous cell carcinoma of the esophagus: The possible involvement of the DPI gene in the 13q34 amplicon
-
Shinomiya T, Mori T, Ariyama Y, et al., Comparative genomic hybridization of squamous cell carcinoma of the esophagus: the possible involvement of the DPI gene in the 13q34 amplicon. Genes Chromosomes Cancer 1999; 24: 337-344.
-
(1999)
Genes Chromosomes Cancer
, vol.24
, pp. 337-344
-
-
Shinomiya, T.1
Mori, T.2
Ariyama, Y.3
-
3
-
-
0036614698
-
TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas
-
Yasui K, Arii S, Zhao C, et al., TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas. Hepatology 2002; 35: 1476-1484.
-
(2002)
Hepatology
, vol.35
, pp. 1476-1484
-
-
Yasui, K.1
Arii, S.2
Zhao, C.3
-
4
-
-
34249298696
-
Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34
-
Abba MC, Fabris VT, Hu Y, et al., Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34. Cancer Res 2007; 67: 4104-4112.
-
(2007)
Cancer Res
, vol.67
, pp. 4104-4112
-
-
Abba, M.C.1
Fabris, V.T.2
Hu, Y.3
-
5
-
-
77954614896
-
Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes
-
Melchor L, Saucedo-Cuevas LP, Munoz-Repeto I, et al., Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes. Breast Cancer Res 2009; 11: R86.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Melchor, L.1
Saucedo-Cuevas, L.P.2
Munoz-Repeto, I.3
-
6
-
-
84867331145
-
Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer
-
Ren S, Xu C, Cui Z, et al., Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer. J Mol Med (Berl) 2012; 90: 1121-1132.
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 1121-1132
-
-
Ren, S.1
Xu, C.2
Cui, Z.3
-
7
-
-
65649105790
-
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
-
Liu L, Lee S, Zhang J, et al., CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis. Mol Cell 2009; 34: 451-460.
-
(2009)
Mol Cell
, vol.34
, pp. 451-460
-
-
Liu, L.1
Lee, S.2
Zhang, J.3
-
8
-
-
79951936931
-
Cul4A is an oncogene in malignant pleural mesothelioma
-
Hung MS, Mao JH, Xu Z, et al., Cul4A is an oncogene in malignant pleural mesothelioma. J Cell Mol Med 2011; 15: 350-358.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 350-358
-
-
Hung, M.S.1
Mao, J.H.2
Xu, Z.3
-
9
-
-
77955485964
-
Gene amplification of the transcription factor DP1 and CTNND1 in human lung cancer
-
Castillo SD, Angulo B, Suarez-Gauthier A, et al., Gene amplification of the transcription factor DP1 and CTNND1 in human lung cancer. J Pathol 2010; 222: 89-98.
-
(2010)
J Pathol
, vol.222
, pp. 89-98
-
-
Castillo, S.D.1
Angulo, B.2
Suarez-Gauthier, A.3
-
10
-
-
33847246805
-
Oncomine 3.0: Genes, pathways, and networks in a collection of 18 000 cancer gene expression profiles
-
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, et al., Oncomine 3.0: genes, pathways, and networks in a collection of 18 000 cancer gene expression profiles. Neoplasia 2007; 9: 166-180.
-
(2007)
Neoplasia
, vol.9
, pp. 166-180
-
-
Rhodes, D.R.1
Kalyana-Sundaram, S.2
Mahavisno, V.3
-
11
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, Gao J, Dogrusoz U, et al., The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012; 2: 401-404.
-
(2012)
Cancer Discov
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
-
12
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, et al., Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013; 6: pl1.
-
(2013)
Sci Signal
, vol.6
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
-
13
-
-
79953036472
-
Transgenic mice for cre-inducible overexpression of the Cul4A gene
-
Li T, Hung MS, Wang Y, et al., Transgenic mice for cre-inducible overexpression of the Cul4A gene. Genesis 2011; 49: 134-141.
-
(2011)
Genesis
, vol.49
, pp. 134-141
-
-
Li, T.1
Hung, M.S.2
Wang, Y.3
-
14
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
Jackson EL, Willis N, Mercer K, et al., Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 2001; 15: 3243-3248.
-
(2001)
Genes Dev
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
-
15
-
-
68149157175
-
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
-
DuPage M, Dooley AL, Jacks T,. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc 2009; 4: 1064-1072.
-
(2009)
Nat Protoc
, vol.4
, pp. 1064-1072
-
-
Dupage, M.1
Dooley, A.L.2
Jacks, T.3
-
16
-
-
51949098691
-
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4-Cdt2 ubiquitin ligase complex
-
Abbas T, Sivaprasad U, Terai K, et al., PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4-Cdt2 ubiquitin ligase complex. Genes Dev 2008; 22: 2496-2506.
-
(2008)
Genes Dev
, vol.22
, pp. 2496-2506
-
-
Abbas, T.1
Sivaprasad, U.2
Terai, K.3
-
17
-
-
51949112601
-
The CRL4-Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing
-
Kim Y, Starostina NG, Kipreos ET,. The CRL4-Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing. Genes Dev 2008; 22: 2507-2519.
-
(2008)
Genes Dev
, vol.22
, pp. 2507-2519
-
-
Kim, Y.1
Starostina, N.G.2
Kipreos, E.T.3
-
18
-
-
57049133181
-
CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation
-
Nishitani H, Shiomi Y, Iida H, et al., CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J Biol Chem 2008; 283: 29045-29052.
-
(2008)
J Biol Chem
, vol.283
, pp. 29045-29052
-
-
Nishitani, H.1
Shiomi, Y.2
Iida, H.3
-
19
-
-
0028363519
-
1 cyclin-Cdk protein kinase activity, is related to p21
-
1 cyclin-Cdk protein kinase activity, is related to p21. Cell 1994; 78: 67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
20
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda M, Cukor B, Tam SW, et al., Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997; 3: 231-234.
-
(1997)
Nat Med
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
-
21
-
-
0031048716
-
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
-
Porter PL, Malone KE, Heagerty PJ, et al., Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 1997; 3: 222-225.
-
(1997)
Nat Med
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
-
22
-
-
41149150219
-
The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
-
Chu IM, Hengst L, Slingerland JM,. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 2008; 8: 253-267.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 253-267
-
-
Chu, I.M.1
Hengst, L.2
Slingerland, J.M.3
-
23
-
-
0036559462
-
Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
-
Philipp-Staheli J, Kim KH, Payne SR, et al., Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. Cancer Cell 2002; 1: 355-368.
-
(2002)
Cancer Cell
, vol.1
, pp. 355-368
-
-
Philipp-Staheli, J.1
Kim, K.H.2
Payne, S.R.3
-
24
-
-
82855181506
-
Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27
-
Yan Y, Zhang X, Legerski RJ,. Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27. Cell Cycle 2011; 10: 4098-4109.
-
(2011)
Cell Cycle
, vol.10
, pp. 4098-4109
-
-
Yan, Y.1
Zhang, X.2
Legerski, R.J.3
-
25
-
-
0242525214
-
Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint
-
Higa LA, Mihaylov IS, Banks DP, et al., Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Nat Cell Biol 2003; 5: 1008-1015.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 1008-1015
-
-
Higa, L.A.1
Mihaylov, I.S.2
Banks, D.P.3
-
26
-
-
33644861713
-
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis
-
Nishitani H, Sugimoto N, Roukos V, et al., Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis. EMBO J 2006; 25: 1126-1136.
-
(2006)
EMBO J
, vol.25
, pp. 1126-1136
-
-
Nishitani, H.1
Sugimoto, N.2
Roukos, V.3
-
27
-
-
5444274523
-
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
-
Hu J, McCall CM, Ohta T, et al., Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nat Cell Biol 2004; 6: 1003-1009.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1003-1009
-
-
Hu, J.1
McCall, C.M.2
Ohta, T.3
-
28
-
-
76149140090
-
Pericentrin in cellular function and disease
-
Delaval B, Doxsey SJ,. Pericentrin in cellular function and disease. J Cell Biol 2010; 188: 181-190.
-
(2010)
J Cell Biol
, vol.188
, pp. 181-190
-
-
Delaval, B.1
Doxsey, S.J.2
-
29
-
-
80054680116
-
Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer
-
To MD, Quigley DA, Mao JH, et al., Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer. Mol Cancer Res 2011; 9: 1339-1345.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1339-1345
-
-
To, M.D.1
Quigley, D.A.2
Mao, J.H.3
-
30
-
-
33644525896
-
High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH
-
Garnis C, Lockwood WW, Vucic E, et al., High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer 2006; 118: 1556-1564.
-
(2006)
Int J Cancer
, vol.118
, pp. 1556-1564
-
-
Garnis, C.1
Lockwood, W.W.2
Vucic, E.3
-
31
-
-
33847264495
-
DDB1 is essential for genomic stability in developing epidermis
-
Cang Y, Zhang J, Nicholas SA, et al., DDB1 is essential for genomic stability in developing epidermis. Proc Natl Acad Sci USA 2007; 104: 2733-2737.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2733-2737
-
-
Cang, Y.1
Zhang, J.2
Nicholas, S.A.3
-
32
-
-
33751331884
-
Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells
-
Cang Y, Zhang J, Nicholas SA, et al., Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell 2006; 127: 929-940.
-
(2006)
Cell
, vol.127
, pp. 929-940
-
-
Cang, Y.1
Zhang, J.2
Nicholas, S.A.3
-
33
-
-
62449293155
-
DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation
-
Kotake Y, Zeng Y, Xiong Y,. DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation. Cancer Res 2009; 69: 1809-1814.
-
(2009)
Cancer Res
, vol.69
, pp. 1809-1814
-
-
Kotake, Y.1
Zeng, Y.2
Xiong, Y.3
-
34
-
-
0032894125
-
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
-
Esteller M, Sanchez-Cespedes M, Rosell R, et al., Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 1999; 59: 67-70.
-
(1999)
Cancer Res
, vol.59
, pp. 67-70
-
-
Esteller, M.1
Sanchez-Cespedes, M.2
Rosell, R.3
-
35
-
-
71849104873
-
P16INK4A inactivation mechanisms in non-small-cell lung cancer patients occupationally exposed to asbestos
-
Andujar P, Wang J, Descatha A, et al., p16INK4A inactivation mechanisms in non-small-cell lung cancer patients occupationally exposed to asbestos. Lung Cancer 2010; 67: 23-30.
-
(2010)
Lung Cancer
, vol.67
, pp. 23-30
-
-
Andujar, P.1
Wang, J.2
Descatha, A.3
-
37
-
-
64749098830
-
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
-
Soucy TA, Smith PG, Milhollen MA, et al., An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature 2009; 458: 732-736.
-
(2009)
Nature
, vol.458
, pp. 732-736
-
-
Soucy, T.A.1
Smith, P.G.2
Milhollen, M.A.3
-
38
-
-
0036925334
-
First-line chemotherapy for NSCLC: An overview of relevant trials
-
Group TAXS
-
Belani CP, Langer C, Group TAXS,. First-line chemotherapy for NSCLC: an overview of relevant trials. Lung Cancer 2002; 38 (suppl 4): 13-19.
-
(2002)
Lung Cancer
, vol.38
, Issue.SUPPL. 4
, pp. 13-19
-
-
Belani, C.P.1
Langer, C.2
-
39
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, et al., Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002; 346: 92-98.
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
40
-
-
84879849959
-
Disrupting protein NEDDylation with MLN4924 is a novel strategy to target cisplatin resistance in ovarian cancer
-
Nawrocki ST, Kelly KR, Smith PG, et al., Disrupting protein NEDDylation with MLN4924 is a novel strategy to target cisplatin resistance in ovarian cancer. Clin Cancer Res 2013; 19: 3577-3590.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3577-3590
-
-
Nawrocki, S.T.1
Kelly, K.R.2
Smith, P.G.3
|