Increasing cGMP-dependent protein kinase activity attenuates unilateral ureteral obstruction-induced renal fibrosis

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 9, 2014, Pages

  Cui, Wenpeng ^b,c   Maimaitiyiming, Hasiyeti ^a,c   Qi, Xinyu ^a,c   Norman, Heather ^a,c   Zhou, Qi ^a,c   Wang, Xiaojun ^c   Fu, Jian ^c   Wang, Shuxia ^a,c  

^a LEXINGTON VA MEDICAL CENTER   (United States)

^b THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

PKG; Renal fibrosis; TGF 1; UUO

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; COLLAGEN TYPE 1; CYCLIC GMP DEPENDENT PROTEIN KINASE 1; INTERCELLULAR ADHESION MOLECULE 1; SILDENAFIL; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL INFILTRATION; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY INTERSTITIUM; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UNILATERAL URETERAL OBSTRUCTION; URETER OBSTRUCTION;

PKG; RENAL FIBROSIS; TGF-Β1; UUO;

ACTINS; ANGIOTENSIN II; ANIMALS; CADHERINS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I; CYTOKINES; DISEASE MODELS, ANIMAL; FIBROSIS; INFLAMMATION MEDIATORS; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MACROPHAGES; MALE; MICE; MICE, TRANSGENIC; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHORYLATION; PIPERAZINES; PURINES; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SULFONES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION; URETERAL OBSTRUCTION;

EID: 84900529172     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00657.2013     Document Type: Article

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