Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 10, 2014, Pages

  Yabluchanskiy, Andriy ^a,b   Ma, Yonggang ^a,b   Chiao, Ying Ann ^c   Lopez, Elizabeth F ^a   Voorhees, Andrew P ^a,d   Toba, Hiroe ^a,b,e   Hall, Michael E ^a,b   Han, Hai Chao ^a,d   Lindsey, Merry L ^a,b,f   Jin, Yu Fang ^a,d  

^a San Antonio Cardiovascular Proteomics Center   (United States)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d The University of Texas at San Antonio   (United States)

^e KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^f G V SONNY MONTGOMERY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Aging; Angiogenesis; Extracellular matrix; Inflammation; MMP 9; Proteomics

Indexed keywords

CHEMOKINE RECEPTOR CCR10; CONNECTIVE TISSUE GROWTH FACTOR; CONTACTIN; CYTOKINE; GELATINASE A; GELATINASE B; INTEGRIN; INTERLEUKIN 13; INTERLEUKIN 1F8; INTERLEUKIN 20; LAMININ; MATRILYSIN; NERVE CELL ADHESION MOLECULE; OSTEONECTIN; STEM CELL FACTOR; STROMELYSIN 2; STROMELYSIN 3; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VON WILLEBRAND FACTOR;

AGING; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CARDIAC AGING; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FEMALE; GENE DELETION; GENE EXPRESSION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

AGING; ANGIOGENESIS; EXTRACELLULAR MATRIX; INFLAMMATION; MMP-9; PROTEOMICS;

AGING; ANIMALS; ENDOTHELIUM, VASCULAR; FEMALE; HEART; HYPERTROPHY; MALE; MATRIX METALLOPROTEINASE 9; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MYOCYTES, CARDIAC; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84900527690     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00090.2014     Document Type: Article

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