Cell invasion in the spheroid sprouting assay: A spatial organisation analysis adaptable to cell behaviour

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Blacher, Silvia ^a   Erpicum, Charlotte ^a   Lenoir, Bénédicte ^a,b   Paupert, Jenny ^a   Moraes, Gustavo ^a   Ormenese, Sandra ^a   Bullinger, Eric ^a   Noel, Agnès ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ANGIOGENESIS; ARTICLE; CELL ASSAY; CELL DENSITY; CELL FUNCTION; CELL INVASION; CELL MIGRATION; CELL STRUCTURE; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CELLULAR PARAMETERS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMAGING SYSTEM; LYMPHANGIOGENESIS; QUANTITATIVE ANALYSIS; SPHEROID CELL; SPROUTING; THREE DIMENSIONAL IMAGING; VALIDATION PROCESS; CELL MOTION; CELL TRACKING; CHEMISTRY; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MULTICELLULAR SPHEROID; NEOVASCULARIZATION, PATHOLOGIC; PROCEDURES; ULTRASTRUCTURE;

ANGIOGENESIS INHIBITOR; TELOMERASE; TERT PROTEIN, HUMAN; VASCULOTROPIN A;

ANGIOGENESIS INHIBITORS; CELL MOVEMENT; CELL TRACKING; ENDOTHELIAL CELLS; HUMANS; IMAGING, THREE-DIMENSIONAL; MICROSCOPY, CONFOCAL; NEOVASCULARIZATION, PATHOLOGIC; SPHEROIDS, CELLULAR; TELOMERASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84900524184     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097019     Document Type: Article

References (37)

1. Noel A, Jost M, Lambert V, Lecomte J, Rakic JM (2007) Anti-angiogenic therapy of exudative age-related macular degeneration: current progress and emerging concepts. Trends Mol Med 13: 345-352. (Pubitemid 47126988)
2. Bruyere F, Melen-Lamalle L, Blacher S, Roland G, Thiry M, et al. (2008) Modeling lymphangiogenesis in a three-dimensional culture system. Nat Methods 5: 431-437. (Pubitemid 351619102)
3. Paupert J, Sounni NE, Noel A (2011) Lymphangiogenesis in post-natal tissue remodeling: lymphatic endothelial cell connection with its environment. Mol Aspects Med 32: 146-158.
4. Karpanen T, Alitalo K (2008) Molecular biology and pathology of lymphangiogenesis. Annu Rev Pathol 3: 367-397. (Pubitemid 351488286)
5. Sleeman JP, Thiele W (2009) Tumor metastasis and the lymphatic vasculature. Int J Cancer 125: 2747-2756.
6. Sleeman JP (2010) Understanding the mechanisms of lymphangiogenesis: a hope for cancer therapy? Phlebolymphology 17: 99-107.
7. Detry B, Erpicum C, Paupert J, Blacher S, Maillard C, et al. (2012) Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase. Blood 119: 5048-5056.
8. Wiig H, Keskin D, Kalluri R (2010) Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol 29: 645-656.
9. Nakatsu MN, Hughes CC (2008) An optimized three-dimensional in vitro model for the analysis of angiogenesis. Methods Enzymol 443: 65-82.
10. Korff T, Augustin HG (1998) Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol 143: 1341-1352. (Pubitemid 28559834)
11. Koh W, Stratman AN, Sacharidou A, Davis GE (2008) In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods Enzymol 443: 83-101.
12. Scheubel RJ, Kahrstedt S, Weber H, Holtz J, Friedrich I, et al. (2006) Depression of progenitor cell function by advanced glycation endproducts (AGEs): potential relevance for impaired angiogenesis in advanced age and diabetes. Exp Gerontol 41: 540-548. (Pubitemid 43765896)
13. Weber H, Claffey J, Hogan M, Pampillon C, Tacke M (2008) Analyses of Titanocenes in the spheroid-based cellular angiogenesis assay. Toxicol In Vitro 22: 531-534. (Pubitemid 351163538)
14. Schulz MM, Reisen F, Zgraggen S, Fischer S, Yuen D, et al. (2012) Phenotypebased high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. Proc Natl Acad Sci U S A 109: E2665-2674.
15. Korff T, Augustin HG (1999) Tensional forces in fibrillar extracellular matrices control directional capillary sprouting. J Cell Sci 112 (Pt 19): 3249-3258. (Pubitemid 29507205)
16. Diehl F, Rossig L, Zeiher AM, Dimmeler S, Urbich C (2007) The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation. Blood 109: 1472-1478. (Pubitemid 46239578)
17. Bagci T, Wu JK, Pfannl R, Ilag LL, Jay DG (2009) Autocrine semaphorin 3A signaling promotes glioblastoma dispersal. Oncogene 28: 3537-3550.
18. Hammer T, Tritsaris K, Hubschmann MV, Gibson J, Nisato RE, et al. (2009) IL-20 activates human lymphatic endothelial cells causing cell signalling and tube formation. Microvasc Res 78: 25-32.
19. De Wever O, Hendrix A, De Boeck A, Westbroek W, Braems G, et al. (2010) Modeling and quantification of cancer cell invasion through collagen type I matrices. Int J Dev Biol 54: 887-896.
20. Nisato RE, Harrison JA, Buser R, Orci L, Rinsch C, et al. (2004) Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. Am J Pathol 165: 11-24. (Pubitemid 38821810)
21. Maquoi E, Sounni NE, Devy L, Olivier F, Frankenne F, et al. (2004) Antiinvasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6- trione derivative, an orally active and selective matrix metalloproteinases inhibitor. Clin Cancer Res 10: 4038-4047. (Pubitemid 38812479)
22. Fusenig NE, Limat A, Stark HJ, Breitkreutz D (1994) Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis. J Dermatol Sci 7 Suppl: S142-151.
23. Frangi A, editor (1998) Multiscale vessel enhancement filtering. Berlin/Heidelberg: Springer. 130-137 p.
24. Soille P, editor (1999) Morphological analysis, Principles, and Application. Berlin: Springer.
25. Gonzalez RC, Woods RE (2008) Digital image processing; 3, editor: Pearson Education.
26. Otsu N (1979) A threshold selection method from a grey level histograms. IEEE Trans Systems, Man, Cybernet 9: 62-66.
27. Korff T, Kimmina S, Martiny-Baron G, Augustin HG (2001) Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J 15: 447-457. (Pubitemid 32141436)
28. Correa de Sampaio P, Auslaender D, Krubasik D, Failla AV, Skepper JN, et al. (2012) A heterogeneous in vitro three dimensional model of tumour-stroma interactions regulating sprouting angiogenesis. PLoS One 7: e30753.
29. Lu P, Weaver VM, Werb Z (2012) The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 196: 395-406.
30. Maquoi E, Assent D, Detilleux J, Pequeux C, Foidart JM, et al. (2012) MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis. Oncogene 31: 480-493.
31. Detry B, Bruyere F, Erpicum C, Paupert J, Lamaye F, et al. (2011) Digging deeper into lymphatic vessel formation in vitro and in vivo. BMC Cell Biol 12: 29.
32. Sabeh F, Shimizu-Hirota R, Weiss SJ (2009) Protease-dependent versus - independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol 185: 11-19.
33. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, et al. (2008) A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest 118: 3860-3869.
34. Ghosh S, Joshi MB, Ivanov D, Feder-Mengus C, Spagnoli GC, et al. (2007) Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis. FEBS Lett 581: 4523-4528. (Pubitemid 47368215)
35. Sodek KL, Brown TJ, Ringuette MJ (2008) Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration. BMC Cancer 8: 223.
36. Hirschhaeuser F, Leidig T, Rodday B, Lindemann C, Mueller-Klieser W (2009) Test system for trifunctional antibodies in 3D MCTS culture. J Biomol Screen 14: 980-990.
37. Theuerkauf RS, Ahammer H, Siwetz M, Helige C, Dohr G, et al. (2010) Measurement of cell death by oxidative stress in three-dimensional spheroids from trophoblast and in fragments of decidua tissue. J Reprod Immunol 85: 63-70.