-
1
-
-
0015694748
-
A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley J, (1973) A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243: 290-293.
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.1
-
2
-
-
18544372618
-
Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells
-
Sonoyama J, Matsumura I, Ezoe S, Satoh Y, Zhang X, et al. (2002) Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells. J Biol Chem 277: 8076-8082.
-
(2002)
J Biol Chem
, vol.277
, pp. 8076-8082
-
-
Sonoyama, J.1
Matsumura, I.2
Ezoe, S.3
Satoh, Y.4
Zhang, X.5
-
3
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, Gathmann I, Kantarjian H, et al. (2006) Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 355: 2408-2417.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
-
5
-
-
79955400117
-
Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
-
Jabbour E, Branford S, Saglio G, Jones D, Cortes J, et al. (2011) Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer 117: 1800-1811.
-
(2011)
Cancer
, vol.117
, pp. 1800-1811
-
-
Jabbour, E.1
Branford, S.2
Saglio, G.3
Jones, D.4
Cortes, J.5
-
6
-
-
75749146563
-
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors
-
Zhang J, Adrian FJ, Jahnke W, Cowan-Jacob SW, Li AG, et al. (2010) Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature 463: 501-506.
-
(2010)
Nature
, vol.463
, pp. 501-506
-
-
Zhang, J.1
Adrian, F.J.2
Jahnke, W.3
Cowan-Jacob, S.W.4
Li, A.G.5
-
7
-
-
45149100643
-
Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism
-
Zhang H, Trachootham D, Lu W, Carew J, Giles FJ, et al. (2008) Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism. Leukemia 22: 1191-1199.
-
(2008)
Leukemia
, vol.22
, pp. 1191-1199
-
-
Zhang, H.1
Trachootham, D.2
Lu, W.3
Carew, J.4
Giles, F.J.5
-
8
-
-
39149090404
-
Effects of carboxyamidotriazole on in vitro models of imatinib-resistant chronic myeloid leukemia
-
Alessandro R, Fontana S, Giordano M, Corrado C, Colomba P, et al. (2008) Effects of carboxyamidotriazole on in vitro models of imatinib-resistant chronic myeloid leukemia. J Cell Physiol 215: 111-121.
-
(2008)
J Cell Physiol
, vol.215
, pp. 111-121
-
-
Alessandro, R.1
Fontana, S.2
Giordano, M.3
Corrado, C.4
Colomba, P.5
-
9
-
-
78649630618
-
Carboxyamidotriazole inhibits cell growth of imatinib-resistant chronic myeloid leukaemia cells including T315I Bcr-Abl mutant by a redox-mediated mechanism
-
Corrado C, Raimondo S, Flugy AM, Fontana S, Santoro A, et al. (2011) Carboxyamidotriazole inhibits cell growth of imatinib-resistant chronic myeloid leukaemia cells including T315I Bcr-Abl mutant by a redox-mediated mechanism. Cancer Lett 300: 205-214.
-
(2011)
Cancer Lett
, vol.300
, pp. 205-214
-
-
Corrado, C.1
Raimondo, S.2
Flugy, A.M.3
Fontana, S.4
Santoro, A.5
-
10
-
-
84864555110
-
Comparative pharmacokinetic profile of carboxyamidotriazole and carboxyamidotriazole-orotate
-
Grover G, Kelly J, Moore G, Jacoby H, Karmali R, et al. (2007) Comparative pharmacokinetic profile of carboxyamidotriazole and carboxyamidotriazole-orotate. Cancer Therapy 5: 437-442.
-
(2007)
Cancer Therapy
, vol.5
, pp. 437-442
-
-
Grover, G.1
Kelly, J.2
Moore, G.3
Jacoby, H.4
Karmali, R.5
-
11
-
-
84857499728
-
Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis
-
Taverna S, Flugy A, Saieva L, Kohn EC, Santoro A, et al. (2011) Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis. Int J Cancer.
-
(2011)
Int J Cancer
-
-
Taverna, S.1
Flugy, A.2
Saieva, L.3
Kohn, E.C.4
Santoro, A.5
-
12
-
-
78049342425
-
Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis
-
Anderson HC, Mulhall D, Garimella R, (2010) Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis. Lab Invest.
-
(2010)
Lab Invest
-
-
Anderson, H.C.1
Mulhall, D.2
Garimella, R.3
-
13
-
-
77951894970
-
V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells
-
D'Asaro M, La Mendola C, Di Liberto D, Orlando V, Todaro M, et al. (2010) V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells. J Immunol 184: 3260-3268.
-
(2010)
J Immunol
, vol.184
, pp. 3260-3268
-
-
D'Asaro, M.1
La Mendola, C.2
Di Liberto, D.3
Orlando, V.4
Todaro, M.5
-
14
-
-
0037490207
-
Exosome release is regulated by a calcium-dependent mechanism in K562 cells
-
Savina A, Furlan M, Vidal M, Colombo MI, (2003) Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem 278: 20083-20090.
-
(2003)
J Biol Chem
, vol.278
, pp. 20083-20090
-
-
Savina, A.1
Furlan, M.2
Vidal, M.3
Colombo, M.I.4
-
15
-
-
0028913347
-
Angiogenesis: role of calcium-mediated signal transduction
-
Kohn EC, Alessandro R, Spoonster J, Wersto RP, Liotta LA, (1995) Angiogenesis: role of calcium-mediated signal transduction. Proc Natl Acad Sci U S A 92: 1307-1311.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 1307-1311
-
-
Kohn, E.C.1
Alessandro, R.2
Spoonster, J.3
Wersto, R.P.4
Liotta, L.A.5
-
17
-
-
68549128599
-
Lung cancer secreted microvesicles: Underappreciated modulators of microenvironment in expanding tumors
-
Wysoczynski M, Ratajczak M, (2009) Lung cancer secreted microvesicles: Underappreciated modulators of microenvironment in expanding tumors. International Jounal of Cancer 125: 1595-1603.
-
(2009)
International Jounal of Cancer
, vol.125
, pp. 1595-1603
-
-
Wysoczynski, M.1
Ratajczak, M.2
-
18
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations
-
Muller M, Cortes J, Kim D, Druker B, Erben P, et al. (2009) Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood 114: 4944-4953.
-
(2009)
Blood
, vol.114
, pp. 4944-4953
-
-
Muller, M.1
Cortes, J.2
Kim, D.3
Druker, B.4
Erben, P.5
-
19
-
-
0642307226
-
Phase II trial of carboxyamidotriazole in patients with relapsed epithelial ovarian cancer
-
Hussain M, Kotz H, Minasian L, Premkumar A, Sarosy G, et al. (2003) Phase II trial of carboxyamidotriazole in patients with relapsed epithelial ovarian cancer. J Clin Oncol 21: 4356-4363.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4356-4363
-
-
Hussain, M.1
Kotz, H.2
Minasian, L.3
Premkumar, A.4
Sarosy, G.5
-
20
-
-
42949170958
-
Phase III randomized, double-blind study of maintenance CAI or placebo in patients with advanced non-small cell lung cancer (NSCLC) after completion of initial therapy (NCCTG 97-24-51)
-
Johnson E, Marks R, Mandrekar S, Hillman S, Hauge M, et al. (2008) Phase III randomized, double-blind study of maintenance CAI or placebo in patients with advanced non-small cell lung cancer (NSCLC) after completion of initial therapy (NCCTG 97-24-51). Lung Cancer 60: 200-207.
-
(2008)
Lung Cancer
, vol.60
, pp. 200-207
-
-
Johnson, E.1
Marks, R.2
Mandrekar, S.3
Hillman, S.4
Hauge, M.5
-
21
-
-
77954637453
-
Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells
-
Naka K, Hoshii T, Hirao A, (2010) Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells. Cancer Sci 101: 1577-1581.
-
(2010)
Cancer Sci
, vol.101
, pp. 1577-1581
-
-
Naka, K.1
Hoshii, T.2
Hirao, A.3
-
23
-
-
0034665786
-
Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes
-
Aguayo A, Kantarjian H, Manshouri T, Gidel C, Estey E, et al. (2000) Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood 96: 2240-2245.
-
(2000)
Blood
, vol.96
, pp. 2240-2245
-
-
Aguayo, A.1
Kantarjian, H.2
Manshouri, T.3
Gidel, C.4
Estey, E.5
-
24
-
-
1942425070
-
Reversal of bone marrow angiogenesis in chronic myeloid leukemia following imatinib mesylate (STI571) therapy
-
Kvasnicka HM, Thiele J, Staib P, Schmitt-Graeff A, Griesshammer M, et al. (2004) Reversal of bone marrow angiogenesis in chronic myeloid leukemia following imatinib mesylate (STI571) therapy. Blood 103: 3549-3551.
-
(2004)
Blood
, vol.103
, pp. 3549-3551
-
-
Kvasnicka, H.M.1
Thiele, J.2
Staib, P.3
Schmitt-Graeff, A.4
Griesshammer, M.5
-
25
-
-
43649085395
-
Microenvironmental regulation of cancer development
-
Hu M, Polyak K, (2008) Microenvironmental regulation of cancer development. Curr Opin Genet Dev 18: 27-34.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 27-34
-
-
Hu, M.1
Polyak, K.2
-
26
-
-
84872829584
-
Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion
-
Mineo M, Garfield SH, Taverna S, Flugy A, De Leo G, et al. (2011) Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion. Angiogenesis.
-
(2011)
Angiogenesis
-
-
Mineo, M.1
Garfield, S.H.2
Taverna, S.3
Flugy, A.4
de Leo, G.5
-
27
-
-
79960981005
-
Signal transduction in vasculogenesis and developmental angiogenesis
-
Patel-Hett S, D'Amore P, (2011) Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol;() 55: 353-363.
-
(2011)
Int J Dev Biol
, vol.55
, pp. 353-363
-
-
Patel-Hett, S.1
D'Amore, P.2
-
28
-
-
58149232586
-
The interleukin-8 pathway in cancer
-
Waugh DJ, Wilson C, (2008) The interleukin-8 pathway in cancer. Clin Cancer Res 14: 6735-6741.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6735-6741
-
-
Waugh, D.J.1
Wilson, C.2
-
29
-
-
58249119700
-
Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors
-
Negaard HF, Iversen N, Bowitz-Lothe IM, Sandset PM, Steinsvik B, et al. (2009) Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors. Leukemia 23: 162-169.
-
(2009)
Leukemia
, vol.23
, pp. 162-169
-
-
Negaard, H.F.1
Iversen, N.2
Bowitz-Lothe, I.M.3
Sandset, P.M.4
Steinsvik, B.5
-
30
-
-
70350681050
-
Paracrine induction of endothelium by tumor exosomes
-
Hood JL, Pan H, Lanza GM, Wickline SA, (2009) Paracrine induction of endothelium by tumor exosomes. Lab Invest 89: 1317-1328.
-
(2009)
Lab Invest
, vol.89
, pp. 1317-1328
-
-
Hood, J.L.1
Pan, H.2
Lanza, G.M.3
Wickline, S.A.4
-
31
-
-
62649095692
-
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
-
Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J, (2009) Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci U S A 106: 3794-3799.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3794-3799
-
-
Al-Nedawi, K.1
Meehan, B.2
Kerbel, R.S.3
Allison, A.C.4
Rak, J.5
|