Mycobacterium tuberculosis phosphoenolpyruvate carboxykinase is regulated by redox mechanisms and interaction with thioredoxin

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13066-13078

  Machová, Iva ^a   Snášel, Jan ^a   Zimmermann, Michael ^b   Laubitz, Daniel ^c   Plocinski, Przemyslaw ^c   Oehlmann, Wulf ^d   Singh, Mahavir ^d   Dostál, Jiří ^a   Sauer, Uwe ^b   Pichová, Iva ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b ETH ZURICH   (Switzerland)

^c INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^d LIONEX DIAGNOSTICS AND THERAPEUTICS GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GENE EXPRESSION; METABOLISM; REACTION KINETICS;

BACTERIAL REPLICATION; CENTRAL CARBON METABOLISMS; FERMENTATIVE PROCESS; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOENOLPYRUVATE CARBOXYKINASE; PROTEIN-PROTEIN INTERACTIONS; REDUCING ENVIRONMENT; TRICARBOXYLIC ACID CYCLE;

PROTEINS;

OXALOACETIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); THIOREDOXIN;

ANAPLEROTIC REACTION KINETICS; ARTICLE; CHEMICAL ENVIRONMENT; CONTROLLED STUDY; ENZYME KINETICS; GENE EXPRESSION; GENE SWITCHING; GLUCONEOGENESIS; HYPOXIA; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ENZYME KINETICS; HYPOXIA; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; OXIDATION-REDUCTION; PHOSPHOENOLPYRUVATE CARBOXYKINASE; THIOREDOXIN;

BACTERIAL PROTEINS; CITRIC ACID CYCLE; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MYCOBACTERIUM TUBERCULOSIS; OXIDATION-REDUCTION; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); THIOREDOXINS;

EID: 84900459867     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.536748     Document Type: Article

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