Preparation and properties of bsa-loaded microspheres based on multi-(amino acid) copolymer for protein delivery

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 1957-1965

  Chen, Xingtao ^a   Lv, Guoyu ^a   Zhang, Jue ^b   Tang, Songchao ^b   Yan, Yonggang ^a   Wu, Zhaoying ^b   Su, Jiacan ^b   Wei, Jie ^b  

^a SICHUAN UNIVERSITY   (China)

^b East China University of Science and Technology   (China)

Author keywords

Degradation; Poly (amino acid) copolymer; Release

Indexed keywords

4 AMINOBUTYRIC ACID; ALANINE; AMINO ACID; AMINOCAPROIC ACID; BENZYL ALCOHOL; BOVINE SERUM ALBUMIN; COPOLYMER; GLUTAMIC ACID; HYDROXYPROLINE; LYSINE; MICROSPHERE; DELAYED RELEASE FORMULATION; MICROCAPSULE;

AMINO ACID SYNTHESIS; ARTICLE; CATALYSIS; EMULSION; OXIDATION; PARTICLE SIZE; SOLVENT EXTRACTION; SYNTHESIS; ADMINISTRATION AND DOSAGE; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DIFFUSION; MATERIALS TESTING; MICROCAPSULE; SURFACE PROPERTY;

AMINO ACIDS; CAPSULES; DELAYED-ACTION PREPARATIONS; DIFFUSION; MATERIALS TESTING; PARTICLE SIZE; SERUM ALBUMIN, BOVINE; SURFACE PROPERTIES;

EID: 84900411718     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S57048     Document Type: Article

References (28)

1. Sinha VR, Trehan A. Biodegradable microspheres for protein delivery. J Control Release. 2003;90(3):261-280.
2. Dai C, Wang B, Zhao H. Microencapsulation peptide and protein drugs delivery system. Colloids Surf B Biointerfaces. 2005;41(2-3): 117-120.
3. Rafati A, Boussahel A, Shakesheff KM, et al. Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications. J Control Release. 2012;162(2):321-329.
4. Freiberg S, Zhu XX. Polymer microspheres for controlled drug release. Int J Pharm. 2004;282(1-2):1-18.
5. Zeng W, Huang J, Hu X, et al. Ionically cross-linked chitosan microspheres for controlled release of bioactive nerve growth factor. Int J Pharm. 2011;421(2):283-290.
6. Shive MS, Anderson JM. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Del Rev. 1997;28(1):5-24.
7. Nath SD, Son S, Sadiasa A, Min YK, Lee BT. Preparation and characterization of PLGA microspheres by the electrospraying method for delivering simvastatin for bone regeneration. Int J Pharm. 2013;443(1-2):87-94.
8. Wang M, Feng Q, Niu X, Tan R, She Z. A spheres-in-sphere structure for improving protein-loading poly(lactide-co-glycolide) microspheres. Polym Degrad Stabil. 2010;95(1):6-13.
9. Lee ES, Park KH, Kang D, et al. Protein complexed with chondroitin sulfate in poly(lactide-co-glycolide) microspheres. Biomaterials. 2007;28(17):2754-2762.
10. Zhang W. Synthesis and characterization of biodegradable copolymers based on 6-aminocaproic acid and α-L-alanine. Polym Bull. 2008;60(2): 323-330.
11. Leopold CS, Friend DR. In vitro study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. Int J Pharm. 1995;126(1):139-145.
12. Zhang W, Huang Y. Biodegradable copoly(amino acid)s based on 6-aminocaproic acid and L-leucine. J Polym Environ. 2011;19(1): 177-181.
13. Li H, Yan Y, Wei J, et al. Bone substitute biomedical material of multi-(amino acid) copolymer: in vitro degradation and biocompatibility. J Mater Sci Mater Med. 2011;22(11):2555-2563.
14. Zhao Z, Shan W, Zhang Y, Li X, Ma J, Yan Y. Fabrication and properties of degradable poly(amino acid)/nano hydroxyapatite bioactive composite. J Appl Polym Sci. 2012;125(4):2502-2509.
15. Jiang J, Zhao Z, Guo Y, Yan Y, Wu D. Syntheses and evaluation of copolymer 6-aminohexanoic acid and 4R-hydroxy-L-proline for bone repair. Advanced Materials Research. 2012;562-564:506-511.
16. Izumikawa S, Yoshioka S, Aso Y, Takeda Y. Preparation of poly(l-lactide) microspheres of different crystalline morphology and effect of crystalline morphology on drug release rate. J Control Release. 1991;15(2):133-140.
17. Freytag T, Dashevsky A, Tillman L, Hardee GE, Bodmeier R. Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres. J Control Release. 2000;69(1): 197-207.
18. Li M, Rouaud O, Poncelet D. Microencapsulation by solvent evaporation: state of the art for process engineering approaches. Int J Pharm. 2008;363(1-2):26-39.
19. Yang YY, Chung TS, Ng NP. Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Biomaterials. 2001;22(3):231-241.
20. Ito F, Fujimori H, Makino K. Factors affecting the loading efficiency of water-soluble drugs in PLGA microspheres. Colloids Surf B Biointerfaces. 2008;61(1):25-29.
21. Yamada T, Onishi H, Machida Y. Sustained release ketoprofen microparticles with ethylcellulose and carboxymethylethylcellulose. J Control Release. 2001;75(3):271-282.
22. Yu Y, Lu T, Zhao W, Sun W, Chen T. Preparation and characterization of BSA-loaded microspheres based on polyanhydrides. J Appl Polym Sci. 2011;121(1):352-358.
23. Yang CY, Tsay SY, Tsiang RC. An enhanced process for encapsulating aspirin in ethyl cellulose microcapsules by solvent evaporation in an O/W emulsion. J Microencapsul. 2000;17(3):269-277.
24. Falco N, Reverchon E, Della Porta G. Injectable PLGA/hydrocortisone formulation produced by continuous supercritical emulsion extraction. Int J Pharm. 2013;441(1-2):589-597.
25. Faisant N, Akiki J, Siepmann F, Benoit JP, Siepmann J. Effects of the type of release medium on drug release from PLGA-based microparticles: experiment and theory. Int J Pharm. 2006;314(2):189-197.
26. Ford Versypt AN, Pack DW, Braatz RD. Mathematical modeling of drug delivery from autocatalytically degradable PLGA microspheres - a review. J Control Release. 2013;165(1):29-37.
27. Bilati U, Allémann E, Doelker E. Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. Eur J Pharm Biopharm. 2005;59(3):375-388.
28. Chi EY, Krishnan S, Randolph TW, Carpenter JF. Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. Pharm Res. 2003;20(9):1325-1336.