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Volumn 26, Issue 5, 2014, Pages 139-146

The expression of DNMT1 in pathologic scar fibroblasts and the effect of 5-aza-2-deoxycytidine on cytokines of pathologic scar fibroblasts

Author keywords

5 aza 2 deoxycytidine; DNA methylationtransferase; Mrna; Pathological scars; Smad7; TGF 1

Indexed keywords


EID: 84900391550     PISSN: 10447946     EISSN: 19432704     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (30)
  • 1
    • 75749104729 scopus 로고    scopus 로고
    • DNMT1 maintains progenitor function in self-renewing somatic tissue
    • Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature. 2010;463(7280):563-567.
    • (2010) Nature. , vol.463 , Issue.7280 , pp. 563-567
    • Sen, G.L.1    Reuter, J.A.2    Webster, D.E.3    Zhu, L.4    Khavari, P.A.5
  • 2
    • 33748998743 scopus 로고    scopus 로고
    • Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival
    • Egger G, Jeong S, Escobar SG, et al. Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci USA. 2006;103(38):14080-14085
    • (2006) Proc Natl Acad Sci USA. , vol.103 , Issue.38 , pp. 14080-14085
    • Egger, G.1    Jeong, S.2    Escobar, S.G.3
  • 3
    • 40849133772 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta superfamily signaling pathways in human disease
    • Gordon KJ, Blobe GC. Role of transforming growth factor-beta superfamily signaling pathways in human disease. Biochim Biophys Acta. 2008;1782(4):197-228.
    • (2008) Biochim Biophys Acta. , vol.1782 , Issue.4 , pp. 197-228
    • Gordon, K.J.1    Blobe, G.C.2
  • 4
    • 3042745446 scopus 로고    scopus 로고
    • TGF-beta: A fibrotic factor in wound scarring and a potential target for anti-scarring gene therapy
    • Liu W, Wang DR, Cao YL. TGF-beta: a fibrotic factor in wound scarring and a potential target for anti-scarring gene therapy. Curr Gene Ther. 2004;4(1):123-136.
    • (2004) Curr Gene Ther. , vol.4 , Issue.1 , pp. 123-136
    • Liu, W.1    Wang, D.R.2    Cao, Y.L.3
  • 5
    • 0036210318 scopus 로고    scopus 로고
    • Review of current progress in the structure and function of Smad proteins
    • Chen W, Fu X, Sheng Z. Review of current progress in the structure and function of Smad proteins. Chin Med J (Engl). 2002;115(3):446-450.
    • (2002) Chin Med J (Engl). , vol.115 , Issue.3 , pp. 446-450
    • Chen, W.1    Fu, X.2    Sheng, Z.3
  • 6
    • 3242802874 scopus 로고    scopus 로고
    • TGF-beta-induced SMAD signaling and gene regulation: Consequences for extracellular matrix remodeling and wound healing
    • Schiller M, Javelaud D, Mauviel A. TGF-beta-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing. J Dematol Sci. 2004;35(2):83-92.
    • (2004) J Dematol Sci. , vol.35 , Issue.2 , pp. 83-92
    • Schiller, M.1    Javelaud, D.2    Mauviel, A.3
  • 7
    • 33747476374 scopus 로고    scopus 로고
    • Keloids and scars: A review of keloids and scars, their pathogenesis, risk factors, and management
    • Slemp AE, Kirschner RE. Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management. Curr Opin Pediatr. 2006;18(4):396-402.
    • (2006) Curr Opin Pediatr. , vol.18 , Issue.4 , pp. 396-402
    • Slemp, A.E.1    Kirschner, R.E.2
  • 8
    • 77956881495 scopus 로고    scopus 로고
    • Epigenetically altered wound healing in keloid fibroblasts
    • Russell SB, Russell JD, Trupin KM, et al. Epigenetically altered wound healing in keloid fibroblasts. J Invest Dermatol. 2010;130(10):2489-2496.
    • (2010) J Invest Dermatol. , vol.130 , Issue.10 , pp. 2489-2496
    • Russell, S.B.1    Russell, J.D.2    Trupin, K.M.3
  • 9
    • 84900429971 scopus 로고    scopus 로고
    • Expression and significance of DNMT1 in human keloid fibroblast
    • in Chinese. Article in Chinese
    • Yang E, Zou QP, Zhang HS. Expression and significance of DNMT1 in human keloid fibroblast [in Chinese]. [Article in Chinese]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2013;29(2):117-20.
    • (2013) Zhonghua Zheng Xing Wai Ke Za Zhi. , vol.29 , Issue.2 , pp. 117-120
    • Yang, E.1    Zou, Q.P.2    Zhang, H.S.3
  • 10
    • 84900407232 scopus 로고    scopus 로고
    • Effect of the methylation enzyme inhibitors of 5-aza-2-deoxycytidine on the TGF-beta/ smad signal transduction pathway in human keloid fibroblasts
    • in Chinese
    • Zou QP, Yang E, Zhang HS. Effect of the methylation enzyme inhibitors of 5-aza-2-deoxycytidine on the TGF-beta/ smad signal transduction pathway in human keloid fibroblasts [in Chinese].Zhonghua Zheng Xing Wai Ke Za Zhi. 2013;29(4):285-289.
    • (2013) Zhonghua Zheng Xing Wai Ke Za Zhi. , vol.29 , Issue.4 , pp. 285-289
    • Zou, Q.P.1    Yang, E.2    Zhang, H.S.3
  • 11
    • 0029919668 scopus 로고    scopus 로고
    • Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers
    • Krajewska M, Krajewski S, Epstein JI, et al. Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol. 1996;148(5): 1567-1576.
    • (1996) Am J Pathol. , vol.148 , Issue.5 , pp. 1567-1576
    • Krajewska, M.1    Krajewski, S.2    Epstein, J.I.3
  • 12
    • 58149127508 scopus 로고    scopus 로고
    • Potential cellular and molecular causes of hypertrophic scar formation
    • van der Veer WM, Bloemen MC, Ulrich MM, et al. Potential cellular and molecular causes of hypertrophic scar formation. Burns. 2009;35(1):15-29.
    • (2009) Burns , vol.35 , Issue.1 , pp. 15-29
    • Van Der Veer, W.M.1    Bloemen, M.C.2    Ulrich, M.M.3
  • 13
    • 84873778023 scopus 로고
    • The aetiotogy of keloids: A review of the literature and a new hypothesis
    • Koonin AJ. The aetiotogy of keloids: a review of the literature and a new hypothesis. S Afr Med J. 1964;38:913-916.
    • (1964) S Afr Med J. , vol.38 , pp. 913-916
    • Koonin, A.J.1
  • 14
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature. 2007;447(7143):425-432.
    • (2007) Nature , vol.447 , Issue.7143 , pp. 425-432
    • Reik, W.1
  • 15
    • 77958580776 scopus 로고    scopus 로고
    • DNA methylation and memory formation
    • Day JJ, Sweatt JD. DNA methylation and memory formation. Nat Neurosci. 2010;13(11):1319-1323.
    • (2010) Nat Neurosci. , vol.13 , Issue.11 , pp. 1319-1323
    • Day, J.J.1    Sweatt, J.D.2
  • 16
    • 24344466882 scopus 로고    scopus 로고
    • DNA methylation and histone modifications: Teaming up to silence genes
    • Fuks F. DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev. 2005;15(5):490-495.
    • (2005) Curr Opin Genet Dev. , vol.15 , Issue.5 , pp. 490-495
    • Fuks, F.1
  • 17
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor T, Laudano A, Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol. 1988;203(4):971-983.
    • (1988) J Mol Biol. , vol.203 , Issue.4 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 18
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992;69(6):915-926.
    • (1992) Cell , vol.69 , Issue.6 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 19
    • 0037224722 scopus 로고    scopus 로고
    • DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
    • Robert MF, Morin S, Beaulieu N, et al. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat Genet. 2003;33(1):61-65.
    • (2003) Nat Genet , vol.33 , Issue.1 , pp. 61-65
    • Robert, M.F.1    Morin, S.2    Beaulieu, N.3
  • 20
    • 0035283201 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    • Mizuno S, Chijiwa T, Okamura T, et al. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood. 2001;97(5):1172-1179.
    • (2001) Blood , vol.97 , Issue.5 , pp. 1172-1179
    • Mizuno, S.1    Chijiwa, T.2    Okamura, T.3
  • 21
    • 77952116121 scopus 로고    scopus 로고
    • Methylation determines fibroblast activation and fibrogenesis in the kidney
    • Bechtel W, McGoohan S, Zeisberg EM, et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010;16(5):544-550.
    • (2010) Nat Med. , vol.16 , Issue.5 , pp. 544-550
    • Bechtel, W.1    McGoohan, S.2    Zeisberg, E.M.3
  • 22
    • 0035313803 scopus 로고    scopus 로고
    • Histone acetyltransferases: Function, structure, and catalysis
    • Marmorstein R, Roth SY. Histone acetyltransferases: function, structure, and catalysis. Curr Opin Genet Dev. 2001;11(2):155-161.
    • (2001) Curr Opin Genet Dev. , vol.11 , Issue.2 , pp. 155-161
    • Marmorstein, R.1    Roth, S.Y.2
  • 23
    • 34548700155 scopus 로고    scopus 로고
    • The HDAC inhibitor trichostatin A inhibits growth of small cell lung cancer cells
    • Platta CS, Greenblatt DY, Kunnimalaiyaan M, Chen H. The HDAC inhibitor trichostatin A inhibits growth of small cell lung cancer cells. J Surg Res. 2007;142(2): 219-226.
    • (2007) J Surg Res. , vol.142 , Issue.2 , pp. 219-226
    • Platta, C.S.1    Greenblatt, D.Y.2    Kunnimalaiyaan, M.3    Chen, H.4
  • 24
    • 80054103882 scopus 로고    scopus 로고
    • Trichostatin A inhibits collagen synthesis and induces apoptosis in keloid fibroblasts
    • Diao JS, Xia WS, Yi CG, et al. Trichostatin A inhibits collagen synthesis and induces apoptosis in keloid fibroblasts. Arch Dermatol Res. 2011;303(8):573-580.
    • (2011) Arch Dermatol Res. , vol.303 , Issue.8 , pp. 573-580
    • Diao, J.S.1    Xia, W.S.2    Yi, C.G.3
  • 25
    • 33746513742 scopus 로고    scopus 로고
    • Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids
    • Sato M. Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids. Acta Derm Venereol. 2006;86(4):300-307.
    • (2006) Acta Derm Venereol. , vol.86 , Issue.4 , pp. 300-307
    • Sato, M.1
  • 27
    • 15544370155 scopus 로고    scopus 로고
    • Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine
    • Enright BP, Sung LY, Chang CC, Yang X, Tian XC. Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine. Biol Reprod. 2005;72(4):944-948.
    • (2005) Biol Reprod. , vol.72 , Issue.4 , pp. 944-948
    • Enright, B.P.1    Sung, L.Y.2    Chang, C.C.3    Yang, X.4    Tian, X.C.5
  • 28
    • 66849111125 scopus 로고    scopus 로고
    • The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2-deoxycytidine
    • Tsuji Y, Kato Y, Tsunoda Y. The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2-deoxycytidine. Zygote. 2009;17(2):109-115.
    • (2009) Zygote , vol.17 , Issue.2 , pp. 109-115
    • Tsuji, Y.1    Kato, Y.2    Tsunoda, Y.3
  • 29
    • 79961045247 scopus 로고    scopus 로고
    • The effects of 5-aza-2-deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts
    • Wang Y, Su J, Wang L, et al. The effects of 5-aza-2-deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts. Cell Reprogram. 2011;13(4):297-306.
    • (2011) Cell Reprogram , vol.13 , Issue.4 , pp. 297-306
    • Wang, Y.1    Su, J.2    Wang, L.3
  • 30
    • 84900419044 scopus 로고    scopus 로고
    • Effect of 5-aza-2-deoxycytidine on human keloid fibroblasts
    • in Chinese
    • Yang E, Zhang Hengshu. Effect of 5-aza-2-deoxycytidine on human keloid fibroblasts [in Chinese]. Journal of Chongqing Med University. 2013;3(38):244-247.
    • (2013) Journal of Chongqing Med University. , vol.3 , Issue.38 , pp. 244-247
    • Yang, E.1    Zhang, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.