Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides

Nucleic Acids Research

Volumn 42, Issue 9, 2014, Pages 5871-5879

  Ward, Amanda J ^a   Norrbom, Michaela ^a   Chun, Seung ^a   Bennett, C Frank ^a   Rigo, Frank ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTISENSE OLIGONUCLEOTIDE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDONUCLEASE; EXONUCLEASE; MESSENGER RNA; PROTEIN SMG6; PROTEIN UPF1; PROTEIN XRN1; RIBONUCLEASE H; RNA INDUCED SILENCING COMPLEX; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXON SKIPPING; FEMALE; GENE EXPRESSION; INTRON RETENTION; MALE; MOUSE; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RNA DEGRADATION; RNA PROCESSING; SOD1 GENE; STAT3 GENE; STOP CODON;

ANIMALS; BASE SEQUENCE; CHROMATIN; EXONS; FEMALE; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; OLIGORIBONUCLEOTIDES; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; SUPEROXIDE DISMUTASE;

EID: 84900339235     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku184     Document Type: Article

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