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Volumn 9, Issue 1, 2014, Pages

Cisplatin induces resistance by triggering differentiation of testicular embryonal carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CISPLATIN; FIBRONECTIN; MESSENGER RNA; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; PACLITAXEL; RETINOIC ACID; SCG10 PROTEIN; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

EID: 84900339167     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087444     Document Type: Article
Times cited : (28)

References (51)
  • 1
    • 79960886187 scopus 로고    scopus 로고
    • Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance
    • Looijenga LH, Gillis AJ, Stoop H, Biermann K, Oosterhuis JW (2011) Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance. Int J Androl 34: e234-251.
    • (2011) Int J Androl , vol.34
    • Looijenga, L.H.1    Gillis, A.J.2    Stoop, H.3    Biermann, K.4    Oosterhuis, J.W.5
  • 3
    • 33644648880 scopus 로고    scopus 로고
    • Testicular germ-cell cancer
    • DOI 10.1016/S0140-6736(06)68305-0, PII S0140673606683050
    • Horwich A, Shipley J, Huddart R (2006) Testicular germ-cell cancer. Lancet 367: 754-765. (Pubitemid 43326294)
    • (2006) Lancet , vol.367 , Issue.9512 , pp. 754-765
    • Horwich, A.1    Shipley, J.2    Huddart, R.3
  • 4
    • 0043240184 scopus 로고    scopus 로고
    • Curing metastatic cancer: Lessons from testicular germ-cell tumours
    • Masters JR, Koberle B (2003) Curing metastatic cancer: lessons from testicular germ-cell tumours. Nat Rev Cancer 3: 517-525. (Pubitemid 37328839)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.7 , pp. 517-525
    • Masters, J.R.W.1    Koberle, B.2
  • 6
    • 46449127405 scopus 로고    scopus 로고
    • Colorectal cancer care knowledge mapping: Identifying priorities for knowledge translation research
    • Gagliardi AR, Wright FC, Grunfeld E, Davis D (2008) Colorectal cancer care knowledge mapping: identifying priorities for knowledge translation research. Cancer Causes Control 19: 615-630.
    • (2008) Cancer Causes Control , vol.19 , pp. 615-630
    • Gagliardi, A.R.1    Wright, F.C.2    Grunfeld, E.3    Davis, D.4
  • 8
    • 35848951634 scopus 로고    scopus 로고
    • DNA damage and cellular differentiation: More questions than responses
    • DOI 10.1002/jcp.21275
    • Simonatto M, Latella L, Puri PL (2007) DNA damage and cellular differentiation: more questions than responses. J Cell Physiol 213: 642-648. (Pubitemid 350058256)
    • (2007) Journal of Cellular Physiology , vol.213 , Issue.3 , pp. 642-648
    • Simonatto, M.1    Latella, L.2    Puri, P.L.3
  • 9
    • 34748915836 scopus 로고    scopus 로고
    • Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles
    • Duale N, Lindeman B, Komada M, Olsen AK, Andreassen A, et al. (2007) Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles. Mol Cancer 6: 53.
    • (2007) Mol Cancer , vol.6 , pp. 53
    • Duale, N.1    Lindeman, B.2    Komada, M.3    Olsen, A.K.4    Andreassen, A.5
  • 10
    • 0023792795 scopus 로고
    • Human teratocarcinomas
    • Andrews PW (1988) Human teratocarcinomas. Biochim Biophys Acta 948: 17-36.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 17-36
    • Andrews, P.W.1
  • 12
    • 0018779369 scopus 로고
    • Establishment and characterization of a human prostatic carcinoma cell line (PC-3)
    • Kaighn ME, Narayan KS, Ohnuki Y, Lechner JF, Jones LW (1979) Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest Urol 17: 16-23. (Pubitemid 9239413)
    • (1979) Investigative Urology , vol.17 , Issue.1 , pp. 16-23
    • Kaighn, M.E.1    Shankar, N.K.2    Ohnuki, Y.3
  • 13
    • 0018090233 scopus 로고
    • Isolation of a human prostate carcinoma cell line (DU 145)
    • Stone KR, Mickey DD, Wunderli H, Mickey GH, Paulson DF (1978) Isolation of a human prostate carcinoma cell line (DU 145). Int J Cancer 21: 274-281. (Pubitemid 8283045)
    • (1978) International Journal of Cancer , vol.21 , Issue.3 , pp. 274-281
    • Stone, K.R.1    Mickey, D.D.2    Wunderli, H.3
  • 14
    • 0024836381 scopus 로고
    • Isolation and characterization of a multipotent clone of human embryonal carcinoma cells
    • DOI 10.1111/j.1432-0436.1989.tb00602.x
    • Pera MF, Cooper S, Mills J, Parrington JM (1989) Isolation and characterization of a multipotent clone of human embryonal carcinoma cells. Differentiation 42: 10-23. (Pubitemid 20011161)
    • (1989) Differentiation , vol.42 , Issue.1 , pp. 10-23
    • Pera, M.F.1    Cooper, S.2    Mills, J.3    Parrington, J.M.4
  • 15
    • 0017770133 scopus 로고
    • Isolation of a human teratoma cell line which expresses F9 antigen
    • Hogan B, Fellous M, Avner P, Jacob F (1977) Isolation of a human teratoma cell line which expresses F9 antigen. Nature 270: 515-518.
    • (1977) Nature , vol.270 , pp. 515-518
    • Hogan, B.1    Fellous, M.2    Avner, P.3    Jacob, F.4
  • 17
    • 0026625502 scopus 로고
    • Establishment and characterization of an in vitro model of acquired resistance to cisplatin in a human testicular nonseminomatous germ cell line
    • Kelland LR, Mistry P, Abel G, Freidlos F, Loh SY, et al. (1992) Establishment and characterization of an in vitro model of acquired resistance to cisplatin in a human testicular nonseminomatous germ cell line. Cancer Res 52: 1710-1716.
    • (1992) Cancer Res , vol.52 , pp. 1710-1716
    • Kelland, L.R.1    Mistry, P.2    Abel, G.3    Freidlos, F.4    Loh, S.Y.5
  • 18
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • Malanchi I, Santamaria-Martinez A, Susanto E, Peng H, Lehr HA, et al. (2012) Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481: 85-89.
    • (2012) Nature , vol.481 , pp. 85-89
    • Malanchi, I.1    Santamaria-Martinez, A.2    Susanto, E.3    Peng, H.4    Lehr, H.A.5
  • 19
    • 0042033824 scopus 로고    scopus 로고
    • Regulation of WNT signaling molecules by retinoic acid during neuronal differentiation in NT2 cells: Threshold model of WNT action
    • review
    • Katoh M (2002) Regulation of WNT signaling molecules by retinoic acid during neuronal differentiation in NT2 cells: threshold model of WNT action (review). Int J Mol Med 10: 683-687.
    • (2002) Int J Mol Med , vol.10 , pp. 683-687
    • Katoh, M.1
  • 20
    • 0031935624 scopus 로고    scopus 로고
    • Differential effects of all-trans-retinoic acid, docosahexaenoic acid, and hexadecylphosphocholine on cisplatin-induced cytotoxicity and apoptosis in a cisplantin-sensitive and resistant human embryonal carcinoma cell line
    • DOI 10.1007/s002800050769
    • Timmer-Bosscha H, de Vries EG, Meijer C, Oosterhuis JW, Mulder NH (1998) Differential effects of all-trans-retinoic acid, docosahexaenoic acid, and hexadecylphosphocholine on cisplatin-induced cytotoxicity and apoptosis in a cisplantin-sensitive and resistant human embryonal carcinoma cell line. Cancer Chemother Pharmacol 41: 469-476. (Pubitemid 28140711)
    • (1998) Cancer Chemotherapy and Pharmacology , vol.41 , Issue.6 , pp. 469-476
    • Timmer-Bosscha, H.1    De Vries, E.G.E.2    Meijer, C.3    Oosterhuis, J.W.4    Mulder, N.H.5
  • 22
    • 0035093267 scopus 로고    scopus 로고
    • ID gene expression varies with lineage during differentiation of pluripotential male germ cell tumor cell lines
    • DOI 10.1007/s004410000340
    • Houldsworth J, Reuter VE, Bosl GJ, Chaganti RS (2001) ID gene expression varies with lineage during differentiation of pluripotential male germ cell tumor cell lines. Cell Tissue Res 303: 371-379. (Pubitemid 32250109)
    • (2001) Cell and Tissue Research , vol.303 , Issue.3 , pp. 371-379
    • Houldsworth, J.1    Reuter, V.E.2    Bosl, G.J.3    Chaganti, R.S.K.4
  • 23
    • 15844383071 scopus 로고    scopus 로고
    • Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells
    • DOI 10.1007/s10142-005-0132-7
    • Chadalavada RS, Houldsworth J, Olshen AB, Bosl GJ, Studer L, et al. (2005) Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells. Funct Integr Genomics 5: 59-69. (Pubitemid 40425087)
    • (2005) Functional and Integrative Genomics , vol.5 , Issue.2 , pp. 59-69
    • Chadalavada, R.S.V.1    Houldsworth, J.2    Olshen, A.B.3    Bosl, G.J.4    Studer, L.5    Chaganti, R.S.K.6
  • 24
    • 84864077183 scopus 로고    scopus 로고
    • Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells
    • Choi SC, Choi JH, Park CY, Ahn CM, Hong SJ, et al. (2012) Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells. J Cell Physiol 227: 3678-3692.
    • (2012) J Cell Physiol , vol.227 , pp. 3678-3692
    • Choi, S.C.1    Choi, J.H.2    Park, C.Y.3    Ahn, C.M.4    Hong, S.J.5
  • 25
    • 78651259053 scopus 로고    scopus 로고
    • NANOG promoter methylation and expression correlation during normal and malignant human germ cell development
    • Nettersheim D, Biermann K, Gillis AJ, Steger K, Looijenga LH, et al. (2011) NANOG promoter methylation and expression correlation during normal and malignant human germ cell development. Epigenetics 6: 114-122.
    • (2011) Epigenetics , vol.6 , pp. 114-122
    • Nettersheim, D.1    Biermann, K.2    Gillis, A.J.3    Steger, K.4    Looijenga, L.H.5
  • 26
    • 67650810301 scopus 로고    scopus 로고
    • Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs
    • Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, et al. (2009) Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev 18: 1093-1108.
    • (2009) Stem Cells Dev , vol.18 , pp. 1093-1108
    • Kashyap, V.1    Rezende, N.C.2    Scotland, K.B.3    Shaffer, S.M.4    Persson, J.L.5
  • 27
    • 84881439613 scopus 로고    scopus 로고
    • Dual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer
    • Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, et al. (2013) Dual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer. J Biol Chem.
    • (2013) J Biol Chem
    • Werner, S.1    Frey, S.2    Riethdorf, S.3    Schulze, C.4    Alawi, M.5
  • 28
    • 80052295267 scopus 로고    scopus 로고
    • Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas
    • Moreno-Bueno G, Salvador F, Martin A, Floristan A, Cuevas EP, et al. (2011) Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas. EMBO Mol Med 3: 528-544.
    • (2011) EMBO Mol Med , vol.3 , pp. 528-544
    • Moreno-Bueno, G.1    Salvador, F.2    Martin, A.3    Floristan, A.4    Cuevas, E.P.5
  • 29
    • 77956275291 scopus 로고    scopus 로고
    • Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors
    • Musch T, Oz Y, Lyko F, Breiling A (2010) Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. PLoS One 5: e10726.
    • (2010) PLoS One , vol.5
    • Musch, T.1    Oz, Y.2    Lyko, F.3    Breiling, A.4
  • 31
    • 0035799528 scopus 로고    scopus 로고
    • Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function
    • DOI 10.1038/sj.onc.1204370
    • Curtin JC, Dragnev KH, Sekula D, Christie AJ, Dmitrovsky E, et al. (2001) Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function. Oncogene 20: 2559-2569. (Pubitemid 32531353)
    • (2001) Oncogene , vol.20 , Issue.20 , pp. 2559-2569
    • Curtin, J.C.1    Dragnev, K.H.2    Sekula, D.3    Christie, A.J.4    Dmitrovsky, E.5    Spinella, M.J.6
  • 32
    • 13944273471 scopus 로고    scopus 로고
    • p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • DOI 10.1038/ncb1211
    • Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, et al. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7: 165-171. (Pubitemid 40268131)
    • (2005) Nature Cell Biology , vol.7 , Issue.2 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5    Appella, E.6    Xu, Y.7
  • 33
    • 33646085352 scopus 로고    scopus 로고
    • Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance
    • Mueller T, Mueller LP, Luetzkendorf J, Voigt W, Simon H, et al. (2006) Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance. Tumour Biol 27: 71-83.
    • (2006) Tumour Biol , vol.27 , pp. 71-83
    • Mueller, T.1    Mueller, L.P.2    Luetzkendorf, J.3    Voigt, W.4    Simon, H.5
  • 34
    • 84859496473 scopus 로고    scopus 로고
    • Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: A possible role of Trp53
    • Chen T, Du J, Lu G (2012) Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53. Mol Biol Rep 39: 1855-1861.
    • (2012) Mol Biol Rep , vol.39 , pp. 1855-1861
    • Chen, T.1    Du, J.2    Lu, G.3
  • 36
    • 48349133869 scopus 로고    scopus 로고
    • Side population cells in human cancers
    • Wu C, Alman BA (2008) Side population cells in human cancers. Cancer Lett 268: 1-9.
    • (2008) Cancer Lett , vol.268 , pp. 1-9
    • Wu, C.1    Alman, B.A.2
  • 37
  • 38
    • 49149107236 scopus 로고    scopus 로고
    • Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
    • Dylla SJ, Beviglia L, Park IK, Chartier C, Raval J, et al. (2008) Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One 3: e2428.
    • (2008) PLoS One , vol.3
    • Dylla, S.J.1    Beviglia, L.2    Park, I.K.3    Chartier, C.4    Raval, J.5
  • 39
    • 79960685139 scopus 로고    scopus 로고
    • A role for cancer stem cells in drug resistance and metastasis in non-small-cell lung cancer
    • Perona R, Lopez-Ayllon BD, de Castro Carpeno J, Belda-Iniesta C (2011) A role for cancer stem cells in drug resistance and metastasis in non-small-cell lung cancer. Clin Transl Oncol 13: 289-293.
    • (2011) Clin Transl Oncol , vol.13 , pp. 289-293
    • Perona, R.1    Lopez-Ayllon, B.D.2    De Castro Carpeno, J.3    Belda-Iniesta, C.4
  • 40
    • 84872325993 scopus 로고    scopus 로고
    • Prognostic impact of the cancer stem cell-related marker NANOG in ovarian serous carcinoma
    • Lee M, Nam EJ, Kim SW, Kim S, Kim JH, et al. (2012) Prognostic impact of the cancer stem cell-related marker NANOG in ovarian serous carcinoma. Int J Gynecol Cancer 22: 1489-1496.
    • (2012) Int J Gynecol Cancer , vol.22 , pp. 1489-1496
    • Lee, M.1    Nam, E.J.2    Kim, S.W.3    Kim, S.4    Kim, J.H.5
  • 41
    • 84867000389 scopus 로고    scopus 로고
    • Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells
    • Izumiya M, Kabashima A, Higuchi H, Igarashi T, Sakai G, et al. (2012) Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells. Anticancer Res 32: 3847-3853.
    • (2012) Anticancer Res , vol.32 , pp. 3847-3853
    • Izumiya, M.1    Kabashima, A.2    Higuchi, H.3    Igarashi, T.4    Sakai, G.5
  • 42
    • 84855781227 scopus 로고    scopus 로고
    • Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
    • Bourguignon LY, Earle C, Wong G, Spevak CC, Krueger K (2012) Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. Oncogene 31: 149-160.
    • (2012) Oncogene , vol.31 , pp. 149-160
    • Bourguignon, L.Y.1    Earle, C.2    Wong, G.3    Spevak, C.C.4    Krueger, K.5
  • 43
    • 79955447216 scopus 로고    scopus 로고
    • p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin
    • Gutekunst M, Oren M, Weilbacher A, Dengler MA, Markwardt C, et al. (2011) p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin. PLoS One 6: e19198.
    • (2011) PLoS One , vol.6
    • Gutekunst, M.1    Oren, M.2    Weilbacher, A.3    Dengler, M.A.4    Markwardt, C.5
  • 44
    • 84874856381 scopus 로고    scopus 로고
    • Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct4
    • Gutekunst M, Mueller T, Weilbacher A, Dengler MA, Bedke J, et al. (2013) Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct4. Cancer Res. 73:1460-1469.
    • (2013) Cancer Res , vol.73 , pp. 1460-1469
    • Gutekunst, M.1    Mueller, T.2    Weilbacher, A.3    Dengler, M.A.4    Bedke, J.5
  • 45
    • 0034212385 scopus 로고    scopus 로고
    • Paclitaxel-induced cell death: Where the cell cycle and apoptosis come together
    • Wang TH, Wang HS, Soong YK (2000) Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 88: 2619-2628.
    • (2000) Cancer , vol.88 , pp. 2619-2628
    • Wang, T.H.1    Wang, H.S.2    Soong, Y.K.3
  • 46
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: Mode of cytotoxic action and molecular basis of resistance
    • DOI 10.1038/sj.onc.1206933, Drug Resistance
    • Siddik ZH (2003) Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22: 7265-7279. (Pubitemid 37487159)
    • (2003) Oncogene , vol.22 , Issue.47 REV. ISS. 6 , pp. 7265-7279
    • Siddik, Z.H.1
  • 47
    • 34247130456 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance
    • DOI 10.1016/j.canlet.2006.10.007, PII S0304383506005611
    • Brozovic A, Osmak M (2007) Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance. Cancer Lett 251: 1-16. (Pubitemid 46589761)
    • (2007) Cancer Letters , vol.251 , Issue.1 , pp. 1-16
    • Brozovic, A.1    Osmak, M.2
  • 48
    • 34247618721 scopus 로고    scopus 로고
    • Concise review: Regulation of embryonic stem cell lineage commitment by mitogen-activated protein kinases
    • DOI 10.1634/stemcells.2006-0612
    • Binetruy B, Heasley L, Bost F, Caron L, Aouadi M (2007) Concise review: regulation of embryonic stem cell lineage commitment by mitogen-activated protein kinases. Stem Cells 25: 1090-1095. (Pubitemid 46684867)
    • (2007) Stem Cells , vol.25 , Issue.5 , pp. 1090-1095
    • Binetruy, B.1    Heasley, L.2    Bost, F.3    Caron, L.4    Aouadi, M.5
  • 49
    • 84868224727 scopus 로고    scopus 로고
    • The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation
    • Varma S, Cao Y, Tagne JB, Lakshminarayanan M, Li J, et al. (2012) The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem 287: 37282-37295.
    • (2012) J Biol Chem , vol.287 , pp. 37282-37295
    • Varma, S.1    Cao, Y.2    Tagne, J.B.3    Lakshminarayanan, M.4    Li, J.5
  • 50
    • 84871312342 scopus 로고    scopus 로고
    • Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression
    • Xiang X, Deng Z, Zhuang X, Ju S, Mu J, et al. (2012) Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression. PLoS One 7: e50781.
    • (2012) PLoS One , vol.7
    • Xiang, X.1    Deng, Z.2    Zhuang, X.3    Ju, S.4    Mu, J.5
  • 51
    • 84870845421 scopus 로고    scopus 로고
    • Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
    • Tsai JH, Donaher JL, Murphy DA, Chau S, Yang J (2012) Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22: 725-736.
    • (2012) Cancer Cell , vol.22 , pp. 725-736
    • Tsai, J.H.1    Donaher, J.L.2    Murphy, D.A.3    Chau, S.4    Yang, J.5


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