Haloemodin as novel antibacterial agent inhibiting DNA gyrase and bacterial topoisomerase i

Journal of Medicinal Chemistry

Volumn 57, Issue 9, 2014, Pages 3707-3714

  Chen, Qianming ^d   Duan, Feixia ^a,b   Li, Xiaohong ^b   Cai, Suping ^c   Xin, Guang ^a   Wang, Yanyan ^a   Du, Dan ^a   He, Shiliang ^a   Huang, Baozhan ^a   Guo, Xiurong ^a   Zhao, Hang ^a,d   Zhang, Rui ^a   Ma, Limei ^a   Liu, Yan ^a   Du, Qigen ^a   Wei, Zeliang ^a   Xing, Zhihua ^a   Liang, Yong ^a   Wu, Xiaohua ^a   Fan, Chengzhong ^a   Ji, Chengjie ^a   Zeng, Dequan ^d   He, Yang ^a   Liu, Xuyang ^c   Huang, Wen ^a   more..

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c JINAN UNIVERSITY   (China)

^d SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE INHIBITOR; GYRASE INHIBITOR; HALOEMODIN; POLYMYXIN B NONAPEPTIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATION; DRUG STRUCTURE; ELECTROPHORESIS; ENZYME INHIBITION; IN VIVO STUDY; KERATITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ANIMALS; ANTI-BACTERIAL AGENTS; EMODIN; ENTEROCOCCUS FAECIUM; KERATITIS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICROBIAL SENSITIVITY TESTS; RABBITS; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS;

EID: 84900322618     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401685f     Document Type: Article

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