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At this point we cannot rule out a mechanism in which the ketimine coordinates to palladium and is deprotonated on the metal. If this were the case, rearrangement from an N-bound azaallyl to a C-bound would be necessary for reductive elimination N-((4-Chlorophenyl)(4-fluorophenyl)methyl)acetamide, which could be synthesized easily from 3ha, is reported to have in vivo antihypoxic and anticonvulsant activity. See
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While this manuscript was under review, Buchwald and Zhu published the enantioselective arylation of 9-aminofluorene-derived alkyl imines
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