Secreted type of amyloid precursor protein induces glial differentiation by stimulating the BMP/Smad signaling pathway

Biochemical and Biophysical Research Communications

Volumn 447, Issue 3, 2014, Pages 394-399

  Kwak, Young Don ^a,b,c   Hendrix, Brandon J ^a   Sugaya, Kiminobu ^a,b  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; BMP Smad signaling pathway; Down syndrome; Glial differentiation; Stem cell therapy

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUTRALIZING ANTIBODY; OSTEOGENIC PROTEIN 1; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; GLIA CELL; HUMAN; HUMAN CELL; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

MUS MUSCULUS;

ALZHEIMER'S DISEASE; AMYLOID PRECURSOR PROTEIN; BMP/SMAD SIGNALING PATHWAY; DOWN SYNDROME; GLIAL DIFFERENTIATION; STEM CELL THERAPY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL LINE, TUMOR; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MICE; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; NEUROGLIA; PEPTIDE FRAGMENTS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMAD PROTEINS; UP-REGULATION;

EID: 84900298588     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.139     Document Type: Article

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