Mechanisms underlying cytokine-mediated cell-fate regulation in the nervous system

Molecular Neurobiology

Volumn 25, Issue 3, 2002, Pages 233-244

  Nakashima, Kinichi ^a   Taga, Tetsuya ^b  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Astocytogenesis; BMP; HLH; IL 6 family of cytokines; LIF; Neural stem cell; Neurogenesis; Smad; STAT

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYTOKINE; INTERLEUKIN 6; SMAD PROTEIN;

ANIMAL; CELL DIFFERENTIATION; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; CYTOLOGY; GLIA; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; STEM CELL; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL FATE; COMPLEX FORMATION; CYTOKINE RELEASE; DNA METHYLATION; IMPLANTATION; NERVOUS SYSTEM DEVELOPMENT; NEUROEPITHELIUM; NONHUMAN; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; CYTOKINES; HUMANS; INTERLEUKIN-6; NEUROGLIA; NEURONS; STEM CELLS;

EID: 0035985229     PISSN: 08937648     EISSN: None     Source Type: Journal    
DOI: 10.1385/MN:25:3:233     Document Type: Article

References (57)

1. CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
2. Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: Specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component
3. Gp130 and the interleukin-6 family of cytokines
4. Smads: Transcriptional activators of TGF-beta responses
5. TGF-beta signalling from cell membrane to nucleus through SMAD proteins
6. Controlling TGF-beta signaling
7. Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
8. Smad6 inhibits signalling by the TGF-beta superfamily
9. Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
10. Stem cells and pattern formation in the nervous system: The possible versus the actual
11. Mammalian neural stem cells
12. Stem cells in the central nervous system
13. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
14. Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
15. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
16. Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype
17. Bone morphogenetic proteins in the nervous system
18. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
19. Astrocyte differentiation mediated by LIF in cooperation with BMP2
20. Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of stat3
21. Signaling crosstalk underlying synergistic induction of astrocyte differentiation by BMPs and IL-6 family of cytokines
22. Phosphorylated CREB binds specifically to the nuclear protein CBR
23. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
24. Differential use of CREB binding protein-coactivator complexes
25. Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins
26. Development of bone morphogenetic protein receptors in the nervous system and possible roles in regulating trkC expression
27. Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation
28. BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis
29. Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system
30. Basic helix-loop-helix genes in neural development
31. Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
32. Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system
33. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation
34. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split
35. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
36. An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene
37. Id helix-loop-helix proteins in cell growth and differentiation
38. Overexpression of Id protein inhibits the muscle differentiation program: In vivo association of Id with E2A proteins
39. The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors
40. Expression of the helix-loop-helix gene Id3 during murine embryonic development
41. Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis
42. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
43. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate
44. rax, Hes1, and notch1 promote the formation of Muller glia by postnatal retinal progenitor cells
45. Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina
46. Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP
47. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
48. Methylation-induced repression: Belts, braces, and chromatin
49. Timing of CNS cell generation: A programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
50. CpG methylation, chromatin structure and gene silencing-a three-way connection
51. DNA methylation: Past, present and future directions
52. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain
53. Identification of a neural stem cell in the adult mammalian central nervous system
54. Traumatic injury-induced BMP7 expression in the adult rat spinal cord
55. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
56. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo
57. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis