Loss-of-heterozygosity facilitates passage through haldane's sieve for saccharomyces cerevisiae undergoing adaptation

Nature Communications

Volumn 5, Issue , 2014, Pages

  Gerstein, A C ^a,b   Kuzmin, A ^a   Otto, S P ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGICIDE; NYSTATIN; ANTIFUNGAL AGENT; FUNGAL DNA;

ADAPTATION; DOMINANCE; FUNGICIDE; HETEROZYGOSITY; MUTATION; YEAST;

ANEUPLOIDY; ARTICLE; ASEXUAL REPRODUCTION; BIOMASS PRODUCTION; CHROMOSOME 12; CLONAL SPECIES; DOMINANCE BEHAVIOR; EVOLUTIONARY ADAPTATION; FLOW CYTOMETRY; FUNGUS MUTATION; GENE CONVERSION; GENE DOSAGE; GENE MUTATION; GROWTH RATE; HALDANE SIEVE; HAPLOTYPE MAP; HETEROZYGOSITY LOSS; HETEROZYGOTE; HOMOLOGOUS RECOMBINATION; MITOTIC RECOMBINATION; NONHUMAN; OPTICAL DENSITY; SACCHAROMYCES CEREVISIAE; ADAPTATION; ANTIFUNGAL RESISTANCE; BIOLOGICAL MODEL; DNA SEQUENCE; DOMINANT GENE; DRUG EFFECTS; EVOLUTION; GENETIC SELECTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; NUCLEOTIDE SEQUENCE;

ADAPTATION, PHYSIOLOGICAL; ANTIFUNGAL AGENTS; BASE SEQUENCE; BIOLOGICAL EVOLUTION; DNA, FUNGAL; DRUG RESISTANCE, FUNGAL; GENES, DOMINANT; LOSS OF HETEROZYGOSITY; MODELS, GENETIC; NYSTATIN; SACCHAROMYCES CEREVISIAE; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84900032946     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4819     Document Type: Article

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