메뉴 건너뛰기




Volumn 27, Issue 6, 2014, Pages 873-880

Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension

Author keywords

amlodipine; blood pressure; combination ther apy; endothelial function; hypertension; statin

Indexed keywords

ACETYLCHOLINE; AMLODIPINE; ATORVASTATIN; C REACTIVE PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SUPEROXIDE; ANTIHYPERTENSIVE AGENT; CALCIUM CHANNEL BLOCKING AGENT; CCL2 PROTEIN, RAT; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NOS3 PROTEIN, RAT; OLDLR1 PROTEIN, RAT; PYRROLE DERIVATIVE; SALT INTAKE;

EID: 84900023214     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1093/ajh/hpt272     Document Type: Article
Times cited : (18)

References (36)
  • 2
    • 1642534463 scopus 로고    scopus 로고
    • Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats
    • Zhou MS, Jaimes EA, Raij L. Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats. Am JHypertens 2004; 17:167-171.
    • (2004) Am JHypertens , vol.17 , pp. 167-171
    • Zhou, M.S.1    Jaimes, E.A.2    Raij, L.3
  • 3
    • 33747749797 scopus 로고    scopus 로고
    • Benazepril combined with either amlodipine or hydrochlorothiazide is more effective than monotherapy for blood pressure control and prevention of end-organ injury in hypertensive Dahl rats
    • Zhou MS, Jaimes EA, Raij L. Benazepril combined with either amlodipine or hydrochlorothiazide is more effective than monotherapy for blood pressure control and prevention of end-organ injury in hypertensive Dahl rats, J Cardiovasc Pharmacol 2006; 48:857-861.
    • (2006) J Cardiovasc Pharmacol , vol.48 , pp. 857-861
    • Zhou, M.S.1    Jaimes, E.A.2    Raij, L.3
  • 4
    • 33746322357 scopus 로고    scopus 로고
    • The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells
    • Batova S, DeWever J, Godfraind T, Balligand JL, Dessy C, Feron O. The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells. Cardiovasc Res 2006; 71:478-485.
    • (2006) Cardiovasc Res , vol.71 , pp. 478-485
    • Batova, S.1    Dewever, J.2    Godfraind, T.3    Balligand, J.L.4    Dessy, C.5    Feron, O.6
  • 6
    • 3542998086 scopus 로고    scopus 로고
    • Atorvastatin prevents end-organ injury in salt-sensitive hypertension: Role of eNOS and oxidant stress
    • Zhou MS, Jaimes EA, Raij L. Atorvastatin prevents end-organ injury in salt-sensitive hypertension: role of eNOS and oxidant stress. Hypertension 2004; 44:186-190.
    • (2004) Hypertension , vol.44 , pp. 186-190
    • Zhou, M.S.1    Jaimes, E.A.2    Raij, L.3
  • 7
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernâandez-Perera O, Pâerez-Sala D, Navarro-Antolâin J, Sâanchez-Pascuala R, Hernâandez G, Dâiaz C, Lamas S. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells, J Clin Invest 1998; 101:2711-2719.
    • (1998) J Clin Invest , vol.101 , pp. 2711-2719
    • Hernâandez-Perera, O.1    Pâerez-Sala, D.2    Navarro-Antolâin, J.3    Sâanchez-Pascuala, R.4    Hernâandez, G.5    Dâiaz, C.6    Lamas, S.7
  • 9
    • 75749143964 scopus 로고    scopus 로고
    • Amlodipine/Atorvastatin: A review of its use in the treatment of hypertension and dyslipidaemia and the prevention of cardiovascular disease
    • Curran MP. Amlodipine/Atorvastatin: a review of its use in the treatment of hypertension and dyslipidaemia and the prevention of cardiovascular disease. Drugs 2010; 70:192-213.
    • (2010) Drugs , vol.70 , pp. 192-213
    • Curran, M.P.1
  • 10
    • 67649669799 scopus 로고    scopus 로고
    • Antihypertensive therapy and the benefits of atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial: Lipid-lowering arm extension
    • Sever PS, Poulter NR, Dahlof B, Wedel H. Antihypertensive therapy and the benefits of atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial: lipid-lowering arm extension, J Hypertens 2009; 27:947-954.
    • (2009) J Hypertens , vol.27 , pp. 947-954
    • Sever, P.S.1    Poulter, N.R.2    Dahlof, B.3    Wedel, H.4
  • 11
    • 84870222983 scopus 로고    scopus 로고
    • Atorvastatin calcium plus amlodipine for the treatment of hypertension
    • Delgado-Montero A, Zamorano JL. Atorvastatin calcium plus amlodipine for the treatment of hypertension. Expert Opin Pharmacother 2012; 13:2673-2685.
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 2673-2685
    • Delgado-Montero, A.1    Zamorano, J.L.2
  • 12
    • 58549118054 scopus 로고    scopus 로고
    • Coadministered amlodipine and atorvastatin produces early improvements in arterial wall compliance in hypertensive patients with dyslipidemia
    • Cohn JN, Wilson DJ, Neutel J, Houston M, Weinberger MH, Grimm R, Jr., Smith DH, Sun W. Coadministered amlodipine and atorvastatin produces early improvements in arterial wall compliance in hypertensive patients with dyslipidemia. Am J Hypertens 2009; 22:137-144.
    • (2009) Am J Hypertens , vol.22 , pp. 137-144
    • Cohn, J.N.1    Wilson, D.J.2    Neutel, J.3    Houston, M.4    Weinberger, M.H.5    Grimm, Jr.R.6    Smith, D.H.7    Sun, W.8
  • 14
    • 3442877524 scopus 로고    scopus 로고
    • Cough and angioedema from angiotensin-converting enzyme inhibitors: New insights into mechanisms and management
    • Dykewicz MS. Cough and angioedema from angiotensin-converting enzyme inhibitors: new insights into mechanisms and management. Curr Opin Allergy Clin Immunol 2004; 4:267-270.
    • (2004) Curr Opin Allergy Clin Immunol , vol.4 , pp. 267-270
    • Dykewicz, M.S.1
  • 15
    • 77149132760 scopus 로고    scopus 로고
    • Vascular inflammation, insulin resistance, and endothelial dysfunction in salt-sensitive hypertension: Role of nuclear factor kappa B activation
    • Zhou MS, Schulman IH, Raij L. Vascular inflammation, insulin resistance, and endothelial dysfunction in salt-sensitive hypertension: role of nuclear factor kappa B activation, J Hypertens 2010; 28:527-535.
    • (2010) J Hypertens , vol.28 , pp. 527-535
    • Zhou, M.S.1    Schulman, I.H.2    Raij, L.3
  • 16
    • 31744449213 scopus 로고    scopus 로고
    • Reduced NAD(P)H oxidase in low renin hypertension: Link among angiotensin II, atherogenesis, and blood pressure
    • Zhou MS, Hernandez Schulman I, Pagano PJ, Jaimes EA, Raij L. Reduced NAD(P)H oxidase in low renin hypertension: link among angiotensin II, atherogenesis, and blood pressure. Hypertension 2006; 47:81-86.
    • (2006) Hypertension , vol.47 , pp. 81-86
    • Zhou, M.S.1    Hernandez Schulman, I.2    Pagano, P.J.3    Jaimes, E.A.4    Raij, L.5
  • 17
    • 0242441471 scopus 로고    scopus 로고
    • In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II
    • Zhou MS, Adam AG, Jaimes EA, Raij L. In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II. Hypertension 2003; 42:945-951.
    • (2003) Hypertension , vol.42 , pp. 945-951
    • Zhou, M.S.1    Adam, A.G.2    Jaimes, E.A.3    Raij, L.4
  • 19
    • 68049102910 scopus 로고    scopus 로고
    • L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages
    • Das R, Burke T, Van Wagoner DR, Plow EE L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages. Circ Res 2009; 105:167-175.
    • (2009) Circ Res , vol.105 , pp. 167-175
    • Das, R.1    Burke, T.2    Van Wagoner, D.R.3    Plow, E.E.4
  • 20
    • 77958462484 scopus 로고    scopus 로고
    • Atorvastatin upregulates nitric oxide synthases with Rho-kinase inhibition and Akt activation in the kidney of spontaneously hypertensive rats
    • Ito D, Ito O, Mori N, Muroya Y, Cao PY, Takashima K, Kanazawa M, Kohzuki M. Atorvastatin upregulates nitric oxide synthases with Rho-kinase inhibition and Akt activation in the kidney of spontaneously hypertensive rats. J Hypertens 2010; 28:2278-2288.
    • (2010) J Hypertens , vol.28 , pp. 2278-2288
    • Ito, D.1    Ito, O.2    Mori, N.3    Muroya, Y.4    Cao, P.Y.5    Takashima, K.6    Kanazawa, M.7    Kohzuki, M.8
  • 21
    • 49949088655 scopus 로고    scopus 로고
    • Renoprotection by statins is linked to a decrease in renal oxidative stress, TGF-beta, and fibronectin with concomitant increase in nitric oxide bioavailability
    • Zhou MS, Schuman IH, Jaimes EA, Raij L. Renoprotection by statins is linked to a decrease in renal oxidative stress, TGF-beta, and fibronectin with concomitant increase in nitric oxide bioavailability. Am J Physiol Renal Physiol 2008; 295:F53-F59.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Zhou, M.S.1    Schuman, I.H.2    Jaimes, E.A.3    Raij, L.4
  • 22
    • 84866025706 scopus 로고    scopus 로고
    • Markers of inflammation in relation to long-term cardiovascular mortality in patients with lower-extremity peripheral arterial disease
    • Urbonaviciene G, Frystyk J, Flyvbjerg A, Urbonavicius S, Henneberg EW, Lindholt JS. Markers of inflammation in relation to long-term cardiovascular mortality in patients with lower-extremity peripheral arterial disease. Int J Cardiol 2012; 160:89-94.
    • (2012) Int J Cardiol , vol.160 , pp. 89-94
    • Urbonaviciene, G.1    Frystyk, J.2    Flyvbjerg, A.3    Urbonavicius, S.4    Henneberg, E.W.5    Lindholt, J.S.6
  • 23
    • 0031613530 scopus 로고    scopus 로고
    • ET(A) receptor blockade prevents increased tissue endothelin-1 vascular hypertrophy and endothelial dysfunction in salt-sensitive hypertension
    • Barton M, d'Uscio LV, Shaw S, Meyer P, Moreau P, Lèuscher TF, Cardiology UHZS. ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension. Hypertension 1998; 31:499-504.
    • (1998) Hypertension , vol.31 , pp. 499-504
    • Barton, M.1    D'Uscio, L.V.2    Shaw, S.3    Meyer, P.4    Moreau, P.5    Lèuscher, T.F.6
  • 24
    • 58149456657 scopus 로고    scopus 로고
    • The use of a single-pill calcium channel blocker/statin combination in the management of hypertension and dyslipidemia: A randomized, placebo-controlled, multicenter study
    • Neutel JM, Bestermann WH, Dyess EM, Graff A, Kursun A, Sutradhar S, Yunis C. The use of a single-pill calcium channel blocker/statin combination in the management of hypertension and dyslipidemia: a randomized, placebo-controlled, multicenter study, J Clin Hypertens (Greenwich, Conn) 2009; 11:22-30.
    • (2009) J Clin Hypertens (Greenwich, Conn) , vol.11 , pp. 22-30
    • Neutel, J.M.1    Bestermann, W.H.2    Dyess, E.M.3    Graff, A.4    Kursun, A.5    Sutradhar, S.6    Yunis, C.7
  • 27
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • Sever PS, Dahlèof B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, Mclnnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003; 361:1149-1158.
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlèof, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McLnnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 28
    • 0035830412 scopus 로고    scopus 로고
    • Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance
    • Feron O, Dessy C, Desager JP, Balligand JL. Hydroxy-methylglutaryl- coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. Circulation 2001;103:113-118.
    • (2001) Circulation , vol.103 , pp. 113-118
    • Feron, O.1    Dessy, C.2    Desager, J.P.3    Balligand, J.L.4
  • 29
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S, Laufs U, Bèaumer AT, Mèuller K, Ahlbory K, Linz W, Itter G, Rèosen R, Bèohm M, Nickenig G. HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension 2001;37:1450-1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Bèaumer, A.T.3    Mèuller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rèosen, R.8    Bèohm, M.9    Nickenig, G.10
  • 31
    • 84867747547 scopus 로고    scopus 로고
    • The antihypertensive actions of statins: Modulation by salt intake
    • Juncos LI, Juncos LA, Garcia NH. The antihypertensive actions of statins: modulation by salt intake. Am J Hypertens 2012; 25:1140-1148.
    • (2012) Am J Hypertens , vol.25 , pp. 1140-1148
    • Juncos, L.I.1    Juncos, L.A.2    Garcia, N.H.3
  • 32
    • 77952519456 scopus 로고    scopus 로고
    • Statins in hypertension: Are they a new class of antihypertensive agents?
    • Feldstein CA. Statins in hypertension: are they a new class of antihypertensive agents? Am J Ther 2010; 17:255-262.
    • (2010) Am J Ther , vol.17 , pp. 255-262
    • Feldstein, C.A.1
  • 33
    • 39849105847 scopus 로고    scopus 로고
    • Thiazide diuretics, endothelial function, and vascular oxidative stress
    • Zhou MS, Schulman IH, Jaimes EA, Raij L. Thiazide diuretics, endothelial function, and vascular oxidative stress, J Hypertens 2008; 26:494-500.
    • (2008) J Hypertens , vol.26 , pp. 494-500
    • Zhou, M.S.1    Schulman, I.H.2    Jaimes, E.A.3    Raij, L.4
  • 36
    • 33644694919 scopus 로고    scopus 로고
    • Rho GTPases, statins, and nitric oxide
    • Rikitake Y Liao JK. Rho GTPases, statins, and nitric oxide. Circ Res 2005;97:1232-1235.
    • (2005) Circ Res , vol.97 , pp. 1232-1235
    • Rikitake, Y.1    Liao, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.