L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages

Circulation Research

Volumn 105, Issue 2, 2009, Pages 167-175

  Das, Riku ^a   Burke, Tim ^a   Van Wagoner, David R ^a   Plow, Edward F ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Amlodipine; Macrophages; Plasminogen; Plasminogen receptors; Verapamil

Indexed keywords

ALPHA ENOLASE; AMLODIPINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; HISTONE H2B; LIPOCORTIN 2; PLASMINOGEN; SMALL INTERFERING RNA; THIOGLYCOLIC ACID; VERAPAMIL; ANTIINFLAMMATORY AGENT; CACNA1C PROTEIN, HUMAN; CAV1.2 PROTEIN, MOUSE; CELL SURFACE RECEPTOR;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD PRESSURE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENZYME REPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MACROPHAGE; MACROPHAGE MIGRATION; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL MOTION; DOWN REGULATION; DRUG EFFECT; FEMALE; GENETICS; MALE; METABOLISM; MOUSE MUTANT; RNA INTERFERENCE; TIME;

AMLODIPINE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; DOWN-REGULATION; FEMALE; HUMANS; MACROPHAGES; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLASMINOGEN; RECEPTORS, CELL SURFACE; RNA INTERFERENCE; TIME FACTORS; VERAPAMIL;

EID: 68049102910     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.200311     Document Type: Article

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