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Volumn 44, Issue 2, 2004, Pages 186-190

Atorvastatin prevents end-organ injury in salt-sensitive hypertension: Role of eNOS and oxidant stress

Author keywords

Hypertension; Nitric oxide synthase; Oxidative stress; Sodium dependent; Statins

Indexed keywords

ANGIOTENSIN; ATORVASTATIN; CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ISOPROSTANE DERIVATIVE; NITRIC OXIDE; STATINE DERIVATIVE; SUPEROXIDE;

EID: 3542998086     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000136395.06810.cf     Document Type: Article
Times cited : (107)

References (39)
  • 1
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in loss of 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomised trial of cholesterol lowering in loss of 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 2
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med. 1998;339:1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 3
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • Sever PS, Dahlof B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 2003; 361:1149-1158.
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlof, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McInnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 4
    • 0033454062 scopus 로고    scopus 로고
    • Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia
    • Glorioso N, Troffa C, Filigheddu F, Dettori F, Soro A, Parpaglia PP, Collatina S, Pahor M. Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia. Hypertension. 1999;34:1281-1286.
    • (1999) Hypertension , vol.34 , pp. 1281-1286
    • Glorioso, N.1    Troffa, C.2    Filigheddu, F.3    Dettori, F.4    Soro, A.5    Parpaglia, P.P.6    Collatina, S.7    Pahor, M.8
  • 5
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, Sanchez-Pascuala R, Hernandez G, Diaz C, Lamas S. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest. 1998;101:2711-2719.
    • (1998) J Clin Invest , vol.101 , pp. 2711-2719
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Navarro-Antolin, J.3    Sanchez-Pascuala, R.4    Hernandez, G.5    Diaz, C.6    Lamas, S.7
  • 7
    • 0033210904 scopus 로고    scopus 로고
    • State-of-the-Art lecture. Statins and blockers of the renin-angiotensin system: Vascular protection beyond their primary mode of action
    • Faggiotto A, Paoletti R. State-of-the-Art lecture. Statins and blockers of the renin-angiotensin system: vascular protection beyond their primary mode of action. Hypertension. 1999;34:987-996.
    • (1999) Hypertension , vol.34 , pp. 987-996
    • Faggiotto, A.1    Paoletti, R.2
  • 8
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S, Laufs U, Baumer AT, Muller K, Ahlbory K, Linz W, Itter G, Rosen R, Bohm M, Nickenig G, HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension. 2001; 37:1450-1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3    Muller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rosen, R.8    Bohm, M.9    Nickenig, G.10
  • 9
    • 0031611941 scopus 로고    scopus 로고
    • Effects of lipid-lowering agents in the Dahl salt-sensitive rat
    • Wilson TW, Alonso-Galicia M, Roman RJ. Effects of lipid-lowering agents in the Dahl salt-sensitive rat. Hypertension. 1998;31:225-231.
    • (1998) Hypertension , vol.31 , pp. 225-231
    • Wilson, T.W.1    Alonso-Galicia, M.2    Roman, R.J.3
  • 10
    • 0036785795 scopus 로고    scopus 로고
    • Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes
    • Delbosc S, Morena M, Djouad F, Ledoucen C, Descomps B, Cristol JP. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes. J Cardiovasc Pharmacol. 2002;40:611-617.
    • (2002) J Cardiovasc Pharmacol , vol.40 , pp. 611-617
    • Delbosc, S.1    Morena, M.2    Djouad, F.3    Ledoucen, C.4    Descomps, B.5    Cristol, J.P.6
  • 11
    • 0037178764 scopus 로고    scopus 로고
    • Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice
    • Vecchione C, Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice. Circ Res. 2002;91:173-179.
    • (2002) Circ Res , vol.91 , pp. 173-179
    • Vecchione, C.1    Brandes, R.P.2
  • 12
    • 0030798337 scopus 로고    scopus 로고
    • Endothelial dysfunction and cardiorenal injury in experimental salt-sensitive hypertension: Effects of antihypertensive therapy
    • Hayakawa H, Coffee K, Raij L. Endothelial dysfunction and cardiorenal injury in experimental salt-sensitive hypertension: effects of antihypertensive therapy. Circulation. 1997;96:2407-2413.
    • (1997) Circulation , vol.96 , pp. 2407-2413
    • Hayakawa, H.1    Coffee, K.2    Raij, L.3
  • 13
    • 0031037543 scopus 로고    scopus 로고
    • The link among nitric oxide synthase activity, endothelial function, and aortic and ventricular hypertrophy in hypertension
    • Hayakawa H, Raij L. The link among nitric oxide synthase activity, endothelial function, and aortic and ventricular hypertrophy in hypertension. Hypertension. 1997;29:235-241.
    • (1997) Hypertension , vol.29 , pp. 235-241
    • Hayakawa, H.1    Raij, L.2
  • 14
    • 0031606271 scopus 로고    scopus 로고
    • Nitric oxide synthase activity and renal injury in genetic hypertension
    • Hayakawa H, Raij L. Nitric oxide synthase activity and renal injury in genetic hypertension. Hypertension. 1998;31:266-270.
    • (1998) Hypertension , vol.31 , pp. 266-270
    • Hayakawa, H.1    Raij, L.2
  • 15
    • 0242441471 scopus 로고    scopus 로고
    • In salt-sensitive hypertension increased superoxide production is linked to a functional upregulation of angiotensin II
    • Zhou MS, Adam AG, Jaimers EA, Raij L. In salt-sensitive hypertension increased superoxide production is linked to a functional upregulation of angiotensin II. Hypertension. 2003;42:945-951.
    • (2003) Hypertension , vol.42 , pp. 945-951
    • Zhou, M.S.1    Adam, A.G.2    Jaimers, E.A.3    Raij, L.4
  • 16
    • 0037336667 scopus 로고    scopus 로고
    • Enhancement of intrarenal angiotensinogen in Dahl salt-sensitive rats on high salt diet
    • Kobori H, Nishiyama A, Abe Y, Navar LG. Enhancement of intrarenal angiotensinogen in Dahl salt-sensitive rats on high salt diet. Hypertension. 2003;41:592-597.
    • (2003) Hypertension , vol.41 , pp. 592-597
    • Kobori, H.1    Nishiyama, A.2    Abe, Y.3    Navar, L.G.4
  • 17
    • 0036773252 scopus 로고    scopus 로고
    • Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKCε and PKCβ
    • Inagaki K, Iwanaga Y, Sarai N, Onozawa Y, Takenaka H, Mochly-Rosen D, Kihara Y. Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKCε and PKCβ. J Mol Cell Cardiol. 2002;34:1377-1385.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1377-1385
    • Inagaki, K.1    Iwanaga, Y.2    Sarai, N.3    Onozawa, Y.4    Takenaka, H.5    Mochly-Rosen, D.6    Kihara, Y.7
  • 18
    • 0242609831 scopus 로고    scopus 로고
    • L-arginine reverse p47phox and gp91phox expression induced by high salt in Dahl rats
    • Fujii S, Zhang L, Igarashi J, Kosaka H. L-arginine reverse p47phox and gp91phox expression induced by high salt in Dahl rats. Hypertension. 2003;42:1014-1020.
    • (2003) Hypertension , vol.42 , pp. 1014-1020
    • Fujii, S.1    Zhang, L.2    Igarashi, J.3    Kosaka, H.4
  • 19
    • 0035096830 scopus 로고    scopus 로고
    • Workshop: Hypertension and cardiovascular risk factors: Role of the angiotensin II-nitric oxide interaction
    • Raij L. Workshop: hypertension and cardiovascular risk factors: role of the angiotensin II-nitric oxide interaction. Hypertension. 2001;37:767-773.
    • (2001) Hypertension , vol.37 , pp. 767-773
    • Raij, L.1
  • 22
    • 1642534463 scopus 로고    scopus 로고
    • Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats
    • Zhou MS, Jaimes EA, Raij L. Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats. Am J Hypertens. 2004;17:167-171.
    • (2004) Am J Hypertens , vol.17 , pp. 167-171
    • Zhou, M.S.1    Jaimes, E.A.2    Raij, L.3
  • 23
    • 0030831948 scopus 로고    scopus 로고
    • Hydrogen peroxide downregulate IL-1-driven mesangial iNOS activity: Implications for glomerulonephritis
    • Jaimers EA, Nath KA, Raij L. Hydrogen peroxide downregulate IL-1-driven mesangial iNOS activity: implications for glomerulonephritis. Am J Physiol. 1997;272:F721-F728.
    • (1997) Am J Physiol , vol.272
    • Jaimers, E.A.1    Nath, K.A.2    Raij, L.3
  • 24
    • 0031613530 scopus 로고    scopus 로고
    • ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension
    • Barton M, d'Uscio LV, Shaw S, Meyer P, Moreau P, Luscher TF. ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension, Hypertension. 1998;31:499-504.
    • (1998) Hypertension , vol.31 , pp. 499-504
    • Barton, M.1    D'Uscio, L.V.2    Shaw, S.3    Meyer, P.4    Moreau, P.5    Luscher, T.F.6
  • 26
    • 0033669593 scopus 로고    scopus 로고
    • Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II
    • Kitamoto S, Egashira K, Kataoka C, Usui M, Koyanagi M, Takemoto M, Takeshita A. Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II. J Hypertens. 2000;18:1795-1800.
    • (2000) J Hypertens , vol.18 , pp. 1795-1800
    • Kitamoto, S.1    Egashira, K.2    Kataoka, C.3    Usui, M.4    Koyanagi, M.5    Takemoto, M.6    Takeshita, A.7
  • 29
    • 0035094570 scopus 로고    scopus 로고
    • Salt sensitivity, pulse pressure, and death in normal and hypertensive humans
    • Weinberger MH, Fineberg NS, Fineberg SE, Weinberger M. Salt sensitivity, pulse pressure, and death in normal and hypertensive humans. Hypertension. 2001;37:429-432.
    • (2001) Hypertension , vol.37 , pp. 429-432
    • Weinberger, M.H.1    Fineberg, N.S.2    Fineberg, S.E.3    Weinberger, M.4
  • 31
    • 0344541709 scopus 로고    scopus 로고
    • Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men
    • Nickenig G, Baumer AT, Temur Y, Kebben D, Jockenhovel F, Bohm M. Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men. Circulation. 1999;100:2131-2134.
    • (1999) Circulation , vol.100 , pp. 2131-2134
    • Nickenig, G.1    Baumer, A.T.2    Temur, Y.3    Kebben, D.4    Jockenhovel, F.5    Bohm, M.6
  • 32
    • 0037062481 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutary CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephrology
    • Danesh FR, Sadeghi MM, Amro N, Philips C, Zeng L, Lin S, Sahai A, Kanwar YS. 3-Hydroxy-3-methylglutary CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephrology. Proc Natl Acad Sci USA. 2002;99:8301-8305.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3    Philips, C.4    Zeng, L.5    Lin, S.6    Sahai, A.7    Kanwar, Y.S.8
  • 33
    • 0037214686 scopus 로고    scopus 로고
    • Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure
    • Satoh S, Ueda Y, Koyanagi M, Kadokami T, Sugano M, Yoshikawa Y, Makino N. Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure. J Mol Cell Cardiol. 2003;35:59-70.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 59-70
    • Satoh, S.1    Ueda, Y.2    Koyanagi, M.3    Kadokami, T.4    Sugano, M.5    Yoshikawa, Y.6    Makino, N.7
  • 34
    • 0142120102 scopus 로고    scopus 로고
    • Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: Effect on endothelial NAD(P)H oxidase system
    • Higashi M, Shimokawa H, Hattori T, Hiroki J, Mukai Y, Ichiki T, Takehashi S, Takeshita A. Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system. Circ Res. 2003;93:767-775.
    • (2003) Circ Res , vol.93 , pp. 767-775
    • Higashi, M.1    Shimokawa, H.2    Hattori, T.3    Hiroki, J.4    Mukai, Y.5    Ichiki, T.6    Takehashi, S.7    Takeshita, A.8
  • 35
    • 0036892061 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells
    • Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Mol Cell Biol. 2002;22:867-877.
    • (2002) Mol Cell Biol , vol.22 , pp. 867-877
    • Ming, X.F.1    Viswambharan, H.2    Barandier, C.3    Ruffieux, J.4    Kaibuchi, K.5    Rusconi, S.6    Yang, Z.7
  • 37
    • 0036311314 scopus 로고    scopus 로고
    • Effect of pravastatin on proteinuria in patients with well-controlled hypertension
    • Lee T, Su S, Tsai C. Effect of pravastatin on proteinuria in patients with well-controlled hypertension. Hypertension. 2002;40:67-73.
    • (2002) Hypertension , vol.40 , pp. 67-73
    • Lee, T.1    Su, S.2    Tsai, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.