Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair

Journal of Orthopaedic Research

Volumn 32, Issue 7, 2014, Pages 944-951

  Sugg, Kristoffer B ^a   Lubardic, Jovan ^a   Gumucio, Jonathan P ^a   Mendias, Christopher L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

epithelial to mesenchymal transition; fibrosis; macrophage; repair; tendon

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BIGLYCAN; CALVASCULIN; CD11B ANTIGEN; CD31 ANTIGEN; CD68 ANTIGEN; CHEMOKINE RECEPTOR CCR7; COLLAGEN TYPE 1; DECORIN; FIBROMODULIN; GELATINASE A; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE 14; MEMBRANE PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL COLLAGENASE; STROMELYSIN; TENOMODULIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXC2; TRANSCRIPTION FACTOR SCLERAXIS; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN;

ACHILLES TENDON; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; MACROPHAGE; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TENDON INJURY; TENDON RECONSTRUCTION; TENOTOMY; UPREGULATION;

EPITHELIAL-TO-MESENCHYMAL TRANSITION; FIBROSIS; MACROPHAGE; REPAIR; TENDON;

ACHILLES TENDON; ANIMALS; CELL DIFFERENTIATION; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; INFLAMMATION; MACROPHAGES; MALE; PHENOTYPE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TENDON INJURIES; TENOTOMY; TIME FACTORS; WOUND HEALING;

EID: 84900017086     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22624     Document Type: Article

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