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Volumn 63, Issue 10, 2006, Pages 1125-1140

The vertebrate connexin family

Author keywords

Chromosome; Connexin; Evolution; Gap junction; Pannexin; Phylogeny; Synteny

Indexed keywords

GAP JUNCTION PROTEIN; MEMBRANE PROTEIN;

EID: 33745313131     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-005-5571-8     Document Type: Review
Times cited : (91)

References (105)
  • 1
    • 51249164287 scopus 로고
    • Über die intracellulare Wasserstoffionenkonzentration unter physiologischen and einigen pathologischen Bedingungen
    • Schmidtmann M. (1925) Über die intracellulare Wasserstoffionenkonzentration unter physiologischen and einigen pathologischen Bedingungen. Z. Ges. Exp. Med. 45: 714-742
    • (1925) Z. Ges. Exp. Med. , vol.45 , pp. 714-742
    • Schmidtmann, M.1
  • 3
    • 70449242819 scopus 로고
    • Transmission at the giant motor synapses of the crayfish
    • Furshpan E. J. and Potter D. D. (1959) Transmission at the giant motor synapses of the crayfish. J. Physiol. 145: 289-325
    • (1959) J. Physiol. , vol.145 , pp. 289-325
    • Furshpan, E.J.1    Potter, D.D.2
  • 4
    • 14844295525 scopus 로고    scopus 로고
    • Expression and functions of neuronal gap junctions
    • Söhl G., Maxeiner S. and Willecke K. (2005) Expression and functions of neuronal gap junctions. Nat. Rev. Neurosci. 6: 191-200
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 191-200
    • Söhl, G.1    Maxeiner, S.2    Willecke, K.3
  • 5
    • 0012614177 scopus 로고
    • New observations on the ultrastructure of the membranes of frog peripheral nerve fibers
    • Robertson J. D. (1957) New observations on the ultrastructure of the membranes of frog peripheral nerve fibers. J. Biophys. Biochem. Cytol. 3: 1043-1051
    • (1957) J. Biophys. Biochem. Cytol. , vol.3 , pp. 1043-1051
    • Robertson, J.D.1
  • 6
    • 0012522443 scopus 로고
    • Cell interconnections in normal human cervical epithelium
    • Karrer H. E. (1960) Cell interconnections in normal human cervical epithelium. J. Biophys. Biochem. Cytol. 7: 181-185
    • (1960) J. Biophys. Biochem. Cytol. , vol.7 , pp. 181-185
    • Karrer, H.E.1
  • 7
    • 0007617492 scopus 로고
    • Some observations on the fine structure of the giant nerve fibers of the earthworm, Eisenia foetida
    • Hama K. (1959) Some observations on the fine structure of the giant nerve fibers of the earthworm, Eisenia foetida. J. Biophys. Biochem. Cytol. 6: 61-66
    • (1959) J. Biophys. Biochem. Cytol. , vol.6 , pp. 61-66
    • Hama, K.1
  • 8
    • 0000210747 scopus 로고
    • Intercellular diffusion
    • Kanno L. and Loewenstein W. R. (1964) Intercellular diffusion. Science 143: 959-960
    • (1964) Science , vol.143 , pp. 959-960
    • Kanno, L.1    Loewenstein, W.R.2
  • 9
    • 78651160044 scopus 로고
    • Studies on an epithelial (gland) cell junction. I. Modifications of surface membrane permeability
    • Loewenstein W. R. and Kanno Y. (1964) Studies on an epithelial (gland) cell junction. I. Modifications of surface membrane permeability. J. Cell Biol. 22: 565-586
    • (1964) J. Cell Biol. , vol.22 , pp. 565-586
    • Loewenstein, W.R.1    Kanno, Y.2
  • 10
    • 0014007039 scopus 로고
    • Cell-to-cell passage of large molecules
    • Kanno Y. and Loewenstein W. R. (1966) Cell-to-cell passage of large molecules. Nature 212: 629-630
    • (1966) Nature , vol.212 , pp. 629-630
    • Kanno, Y.1    Loewenstein, W.R.2
  • 11
    • 0023033171 scopus 로고
    • Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein
    • Kumar N. M. and Gilula N. B. (1986) Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein. J. Cell Biol. 103: 767-776
    • (1986) J. Cell Biol. , vol.103 , pp. 767-776
    • Kumar, N.M.1    Gilula, N.B.2
  • 12
    • 0022531305 scopus 로고
    • Molecular cloning of cDNA for rat liver gap junction protein
    • Paul D. L. (1986) Molecular cloning of cDNA for rat liver gap junction protein. J. Cell Biol. 103: 123-134
    • (1986) J. Cell Biol. , vol.103 , pp. 123-134
    • Paul, D.L.1
  • 13
    • 0023551497 scopus 로고
    • Connexin43: A protein from rat heart homologous to a gap junction protein from liver
    • Beyer E. C., Paul D. L. and Goodenough D. A. (1987) Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J. Cell Biol. 105: 2621-2629
    • (1987) J. Cell Biol. , vol.105 , pp. 2621-2629
    • Beyer, E.C.1    Paul, D.L.2    Goodenough, D.A.3
  • 14
    • 0024787405 scopus 로고
    • Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA
    • Zhang J.-T. and Nicholson B. J. (1989) Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA. J. Cell Biol. 109: 3391-3401
    • (1989) J. Cell Biol. , vol.109 , pp. 3391-3401
    • Zhang, J.-T.1    Nicholson, B.J.2
  • 15
    • 0024075029 scopus 로고
    • Sequence and developmental expression of mRNA coding for a gap junction protein in Xenopus
    • Gimlich R. L., Kumar N. M. and Gilula N. B. (1988) Sequence and developmental expression of mRNA coding for a gap junction protein in Xenopus. J. Cell Biol. 107: 1065-1073
    • (1988) J. Cell Biol. , vol.107 , pp. 1065-1073
    • Gimlich, R.L.1    Kumar, N.M.2    Gilula, N.B.3
  • 16
    • 0024522979 scopus 로고
    • Cloning and expression of a Xenopus embryonic gap junction protein
    • Ebihara L., Beyer E. C., Swenson K. I., Paul D. L. and Goodenough D. A. (1989) Cloning and expression of a Xenopus embryonic gap junction protein. Science 243: 1194-1195
    • (1989) Science , vol.243 , pp. 1194-1195
    • Ebihara, L.1    Beyer, E.C.2    Swenson, K.I.3    Paul, D.L.4    Goodenough, D.A.5
  • 17
    • 0025287594 scopus 로고
    • Expression of the gap junction protein connexin43 in embryonic chick lens: Molecular cloning, ultrastructural localization, and post-translational phosphorylation
    • Musil L. S., Beyer E. C. and Goodenough D. A. (1990) Expression of the gap junction protein connexin43 in embryonic chick lens: molecular cloning, ultrastructural localization, and post-translational phosphorylation. J. Membr. Biol. 116: 163-175
    • (1990) J. Membr. Biol. , vol.116 , pp. 163-175
    • Musil, L.S.1    Beyer, E.C.2    Goodenough, D.A.3
  • 18
    • 0025108761 scopus 로고
    • Molecular cloning and developmental expression of two chick embryo gap junction proteins
    • Beyer E. C. (1990) Molecular cloning and developmental expression of two chick embryo gap junction proteins. J. Biol. Chem. 265: 14439-14443
    • (1990) J. Biol. Chem. , vol.265 , pp. 14439-14443
    • Beyer, E.C.1
  • 19
    • 0028129661 scopus 로고
    • Connexin messenger ribonucleic acids in the ovary of Atlantic croaker: Molecular cloning and characterization, hormonal control, and correlation with appearance of oocyte maturational competence
    • Yoshizaki G., Patiño R. and Thomas P. (1994) Connexin messenger ribonucleic acids in the ovary of Atlantic croaker: molecular cloning and characterization, hormonal control, and correlation with appearance of oocyte maturational competence. Biol. Reprod. 51: 493-503
    • (1994) Biol. Reprod. , vol.51 , pp. 493-503
    • Yoshizaki, G.1    Patiño, R.2    Thomas, P.3
  • 20
    • 0030022029 scopus 로고    scopus 로고
    • Connexin 35: A gap-junctional protein expressed preferentially in the skate retina
    • O'Brien J., Al-Ubaidi M. R. and Ripps H. (1996) Connexin 35: a gap-junctional protein expressed preferentially in the skate retina. Mol. Biol. Cell 7: 233-243
    • (1996) Mol. Biol. Cell , vol.7 , pp. 233-243
    • O'Brien, J.1    Al-Ubaidi, M.R.2    Ripps, H.3
  • 21
    • 0347126503 scopus 로고    scopus 로고
    • An update on connexin genes and their nomenclature in mouse and man
    • Söhl G. and Willecke K. (2003) An update on connexin genes and their nomenclature in mouse and man. Cell Commun. Adhes. 10: 173-180
    • (2003) Cell Commun. Adhes. , vol.10 , pp. 173-180
    • Söhl, G.1    Willecke, K.2
  • 22
    • 25144478470 scopus 로고    scopus 로고
    • The connexin gene family in mammals
    • Cruciani V. and Mikalsen S.-O. (2005) The connexin gene family in mammals. Biol. Chem. 386: 325-332
    • (2005) Biol. Chem. , vol.386 , pp. 325-332
    • Cruciani, V.1    Mikalsen, S.-O.2
  • 23
    • 33644832569 scopus 로고    scopus 로고
    • Xenopus connexins: How frogs bridge the gap
    • de Boer T. P. and Van der Heyden M. A. G. (2005) Xenopus connexins: how frogs bridge the gap. Differentiation 73: 330-340
    • (2005) Differentiation , vol.73 , pp. 330-340
    • De Boer, T.P.1    Van Der Heyden, M.A.G.2
  • 24
    • 0023269077 scopus 로고
    • Selective disruption of gap junctional communication interferes with a patterning process in Hydra
    • Fraser S. E., Green C. R., Bode H. R. and Gilula N. B. (1987) Selective disruption of gap junctional communication interferes with a patterning process in Hydra. Science 237: 49-55
    • (1987) Science , vol.237 , pp. 49-55
    • Fraser, S.E.1    Green, C.R.2    Bode, H.R.3    Gilula, N.B.4
  • 25
    • 0000039665 scopus 로고
    • A study of the structure and distribution of the nexus
    • Dewey M. M. and Barr L. (1964) A study of the structure and distribution of the nexus. J. Cell Biol. 23: 553-585
    • (1964) J. Cell Biol. , vol.23 , pp. 553-585
    • Dewey, M.M.1    Barr, L.2
  • 26
    • 0033620627 scopus 로고    scopus 로고
    • Drosophila has several genes for gap junction proteins
    • Curtin K. D., Zhang Z. and Wyman R. J. (1999) Drosophila has several genes for gap junction proteins. Gene 232: 191-201
    • (1999) Gene , vol.232 , pp. 191-201
    • Curtin, K.D.1    Zhang, Z.2    Wyman, R.J.3
  • 27
    • 0035012765 scopus 로고    scopus 로고
    • Innexins get into the gap
    • Phelan P. and Starich T. A. (2001) Innexins get into the gap. BioEssays 23: 388-396
    • (2001) BioEssays , vol.23 , pp. 388-396
    • Phelan, P.1    Starich, T.A.2
  • 30
    • 18944394972 scopus 로고    scopus 로고
    • Evolution of gap junction proteins - The pannexin alternative
    • Panchin Y. V. (2005) Evolution of gap junction proteins - the pannexin alternative. J. Exp. Biol. 208: 1415-1419
    • (2005) J. Exp. Biol. , vol.208 , pp. 1415-1419
    • Panchin, Y.V.1
  • 31
    • 20444415972 scopus 로고    scopus 로고
    • Innexins: Members of an evolutionarily conserved family of gap-junction proteins
    • Phelan P. (2005) Innexins: members of an evolutionarily conserved family of gap-junction proteins. Biochim. Biophys. Acta 1711: 225-245
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 225-245
    • Phelan, P.1
  • 32
    • 0018382741 scopus 로고
    • Junctional intercellular communication and the control of growth
    • Loewenstein W. R. (1979) Junctional intercellular communication and the control of growth. Biochim. Biophys. Acta 560: 1-65
    • (1979) Biochim. Biophys. Acta , vol.560 , pp. 1-65
    • Loewenstein, W.R.1
  • 33
    • 0029742875 scopus 로고    scopus 로고
    • The role of gap junction membrane channels in development
    • Lo C. W. (1996) The role of gap junction membrane channels in development. J. Bioenerg. Biomembr. 28: 379-385
    • (1996) J. Bioenerg. Biomembr. , vol.28 , pp. 379-385
    • Lo, C.W.1
  • 34
    • 0035096676 scopus 로고    scopus 로고
    • Connexin mutations in skin disease and hearing loss
    • Kelsell D. P., Di W. L. and Houseman M. J. (2001) Connexin mutations in skin disease and hearing loss. Am. J. Hum. Genet. 68: 559-568
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 559-568
    • Kelsell, D.P.1    Di, W.L.2    Houseman, M.J.3
  • 35
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Söhl G. and Willecke K. (2004) Gap junctions and the connexin protein family. Cardiovasc. Res. 62: 228-232
    • (2004) Cardiovasc. Res. , vol.62 , pp. 228-232
    • Söhl, G.1    Willecke, K.2
  • 36
    • 1642396591 scopus 로고    scopus 로고
    • Connexin disorders of the ear, skin, and lens
    • Gerido D. A. and White T. W. (2004) Connexin disorders of the ear, skin, and lens. Biochim. Biophys. Acta 1662: 159-170
    • (2004) Biochim. Biophys. Acta , vol.1662 , pp. 159-170
    • Gerido, D.A.1    White, T.W.2
  • 37
    • 1642377170 scopus 로고    scopus 로고
    • Gap junctions and neurological disorders of the central nervous system
    • Nakase T. and Naus C. C. (2004) Gap junctions and neurological disorders of the central nervous system. Biochim. Biophys. Acta 1662: 149-158
    • (2004) Biochim. Biophys. Acta , vol.1662 , pp. 149-158
    • Nakase, T.1    Naus, C.C.2
  • 38
    • 0036872373 scopus 로고    scopus 로고
    • Connexins, gap junctional intercellular communication and kinases
    • Cruciani V. and Mikalsen S.-O. (2002) Connexins, gap junctional intercellular communication and kinases. Biol. Cell 94: 433-443
    • (2002) Biol. Cell , vol.94 , pp. 433-443
    • Cruciani, V.1    Mikalsen, S.-O.2
  • 39
    • 0036955065 scopus 로고    scopus 로고
    • Cancer chemoprevention by connexins
    • Vine A. L. and Bertram J. S. (2002) Cancer chemoprevention by connexins. Cancer Metastasis Rev. 21: 199-216
    • (2002) Cancer Metastasis Rev. , vol.21 , pp. 199-216
    • Vine, A.L.1    Bertram, J.S.2
  • 40
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: Their regulation and functions
    • Sáez J. C., Berthoud V. M., Brañes M. C., Martínez A. D. and Beyer E. C. (2003) Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev. 83: 1359-1400
    • (2003) Physiol. Rev. , vol.83 , pp. 1359-1400
    • Sáez, J.C.1    Berthoud, V.M.2    Brañes, M.C.3    Martínez, A.D.4    Beyer, E.C.5
  • 41
    • 0037382614 scopus 로고    scopus 로고
    • Beyond the gap: Functions of unpaired connexon channels
    • Goodenough D. A. and Paul D. L. (2003) Beyond the gap: functions of unpaired connexon channels. Nat. Rev. Mol. Cell Biol. 4: 285-294
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 285-294
    • Goodenough, D.A.1    Paul, D.L.2
  • 42
    • 28944433824 scopus 로고    scopus 로고
    • Temporal regulation of connexin phosphorylation in embryonic and adult tissues
    • King T. J. and Lampe P. D. (2005) Temporal regulation of connexin phosphorylation in embryonic and adult tissues. Biochim. Biophys. Acta 1719: 24-35
    • (2005) Biochim. Biophys. Acta , vol.1719 , pp. 24-35
    • King, T.J.1    Lampe, P.D.2
  • 43
    • 8444245596 scopus 로고    scopus 로고
    • Connexins and cell signaling in development and disease
    • Wei C.-J., Xu X. and Lo C. W. (2004) Connexins and cell signaling in development and disease. Annu. Rev. Cell Dev. Biol. 20: 811-838
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 811-838
    • Wei, C.-J.1    Xu, X.2    Lo, C.W.3
  • 44
    • 15944387795 scopus 로고    scopus 로고
    • Emerging complexities in identity and function of glial connexins
    • Theis M., Söhl G., Eiberger J. and Willecke K. (2005) Emerging complexities in identity and function of glial connexins. Trends Neurosci. 28: 188-195
    • (2005) Trends Neurosci. , vol.28 , pp. 188-195
    • Theis, M.1    Söhl, G.2    Eiberger, J.3    Willecke, K.4
  • 45
    • 0035704411 scopus 로고    scopus 로고
    • Emerging issues of connexin channels: Biophysics fills the gap
    • Harris A. L. (2001) Emerging issues of connexin channels: biophysics fills the gap. Q. Rev. Biophys. 34: 325-472
    • (2001) Q. Rev. Biophys. , vol.34 , pp. 325-472
    • Harris, A.L.1
  • 46
    • 20444420130 scopus 로고    scopus 로고
    • Gap junction- and hemichannel-independent actions of connexins
    • Jiang J. X. and Gu S. (2005) Gap junction- and hemichannel-independent actions of connexins. Biochim. Biophys. Acta 1711: 208-214
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 208-214
    • Jiang, J.X.1    Gu, S.2
  • 48
    • 0345168060 scopus 로고    scopus 로고
    • Expression of connexin48.5, connexin44.1, and connexin43 during zebrafish (Danio rerio) lens development
    • Cheng S., Christie T. and Valdimarsson G. (2003) Expression of connexin48.5, connexin44.1, and connexin43 during zebrafish (Danio rerio) lens development. Dev. Dyn. 228: 709-715
    • (2003) Dev. Dyn. , vol.228 , pp. 709-715
    • Cheng, S.1    Christie, T.2    Valdimarsson, G.3
  • 49
    • 0031959735 scopus 로고    scopus 로고
    • A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant 'zonular pulverulent' cataract, on chromosome 1q
    • Shiels A., Mackay D., Ionides A., Berry V., Moore A. and Bhattacharya S. (1998) A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant 'zonular pulverulent' cataract, on chromosome 1q. Am. J. Hum. Genet. 62: 526-532
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 526-532
    • Shiels, A.1    Mackay, D.2    Ionides, A.3    Berry, V.4    Moore, A.5    Bhattacharya, S.6
  • 50
    • 0032476578 scopus 로고    scopus 로고
    • Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts
    • White T. W., Goodenough D. A. and Paul D. L. (1998) Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts. J. Cell Biol. 143: 815-825
    • (1998) J. Cell Biol. , vol.143 , pp. 815-825
    • White, T.W.1    Goodenough, D.A.2    Paul, D.L.3
  • 52
    • 0031283282 scopus 로고    scopus 로고
    • 3 connexin gene leads to proteolysis and cataractogenesis in mice
    • 3 connexin gene leads to proteolysis and cataractogenesis in mice. Cell 91: 833-843
    • (1997) Cell , vol.91 , pp. 833-843
    • Gong, X.1    Li, E.2    Klier, G.3    Huang, Q.4    Wu, Y.5    Lei, H.6
  • 53
    • 27544470247 scopus 로고    scopus 로고
    • The detection of hamster connexins: A comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse
    • Cruciani V., Heintz K.-M., Husøy T., Hovig E., Warren D. J. and Mikalsen S.-O. (2004) The detection of hamster connexins: a comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse. Cell Commun. Adhes. 11: 155-171
    • (2004) Cell Commun. Adhes. , vol.11 , pp. 155-171
    • Cruciani, V.1    Heintz, K.-M.2    Husøy, T.3    Hovig, E.4    Warren, D.J.5    Mikalsen, S.-O.6
  • 54
    • 0042530121 scopus 로고    scopus 로고
    • Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues
    • Söhl G., Nielsen P. A., Eiberger J. and Willecke K. (2003) Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues. Cell Commun. Adhes. 10: 27-36
    • (2003) Cell Commun. Adhes. , vol.10 , pp. 27-36
    • Söhl, G.1    Nielsen, P.A.2    Eiberger, J.3    Willecke, K.4
  • 55
    • 0035504763 scopus 로고    scopus 로고
    • Understanding human disease mutations through the use of interspecific genetic variation
    • Miller M. P. and Kumar S. (2001) Understanding human disease mutations through the use of interspecific genetic variation. Hum. Mol. Genet. 10: 2319-2328
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2319-2328
    • Miller, M.P.1    Kumar, S.2
  • 56
    • 0346882600 scopus 로고    scopus 로고
    • Quantifying the intragenic distribution of human disease mutations
    • Miller M. P., Parker J. D., Rissing S. W. and Kumar S. (2003) Quantifying the intragenic distribution of human disease mutations. Ann. Hum. Genet. 67: 567-579
    • (2003) Ann. Hum. Genet. , vol.67 , pp. 567-579
    • Miller, M.P.1    Parker, J.D.2    Rissing, S.W.3    Kumar, S.4
  • 59
    • 0035985057 scopus 로고    scopus 로고
    • Structural and functional diversity of connexin genes in the mouse and human genome
    • Willecke K., Eiberger J., Degen J., Eckardt D., Romualdi A., Güldenagel M. et al. (2002) Structural and functional diversity of connexin genes in the mouse and human genome. Biol. Chem. 383: 725-737
    • (2002) Biol. Chem. , vol.383 , pp. 725-737
    • Willecke, K.1    Eiberger, J.2    Degen, J.3    Eckardt, D.4    Romualdi, A.5    Güldenagel, M.6
  • 60
    • 0024165145 scopus 로고
    • Topology of the Mr 27,000 liver gap junction protein: Cytoplasmic localization of amino- and carboxyl termini and a hydrophilic domain which is protease-hypersensitive
    • Hertzberg E. L., Disher R. M., Tiller A. A., Zhou Y. and Cook R. G. (1988) Topology of the Mr 27,000 liver gap junction protein: cytoplasmic localization of amino- and carboxyl termini and a hydrophilic domain which is protease-hypersensitive. J. Biol. Chem. 263: 19105-19111
    • (1988) J. Biol. Chem. , vol.263 , pp. 19105-19111
    • Hertzberg, E.L.1    Disher, R.M.2    Tiller, A.A.3    Zhou, Y.4    Cook, R.G.5
  • 61
    • 0028077475 scopus 로고
    • Membrane insertion of gap junction connexins: Polytopic channel forming membrane proteins
    • Falk M. M., Kumar N. M. and Gilula N. B. (1994) Membrane insertion of gap junction connexins: polytopic channel forming membrane proteins. J. Cell Biol. 127: 343-355
    • (1994) J. Cell Biol. , vol.127 , pp. 343-355
    • Falk, M.M.1    Kumar, N.M.2    Gilula, N.B.3
  • 62
    • 0025831254 scopus 로고
    • Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31
    • Hoh J. H., John S. A. and Revel J.-P. (1991) Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31. J. Biol. Chem. 266: 6524-6531
    • (1991) J. Biol. Chem. , vol.266 , pp. 6524-6531
    • Hoh, J.H.1    John, S.A.2    Revel, J.-P.3
  • 63
    • 0026575430 scopus 로고
    • Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: Molecular cloning of mouse connexin31 and -45 cDNAs
    • Hennemann H., Schwarz H. J. and Willecke K. (1992) Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: molecular cloning of mouse connexin31 and -45 cDNAs. Eur. J Cell Biol. 57: 51-58
    • (1992) Eur. J. Cell Biol. , vol.57 , pp. 51-58
    • Hennemann, H.1    Schwarz, H.J.2    Willecke, K.3
  • 64
    • 1642273622 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of zfCx52.6: A novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina
    • Zoidl G., Bruzzone R., Weickert S., Kremer M., Zoidl C., Mitropoulou G. et al. (2004) Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina. J. Biol. Chem. 279: 2913-2921
    • (2004) J. Biol. Chem. , vol.279 , pp. 2913-2921
    • Zoidl, G.1    Bruzzone, R.2    Weickert, S.3    Kremer, M.4    Zoidl, C.5    Mitropoulou, G.6
  • 65
    • 4344706379 scopus 로고    scopus 로고
    • Connexin 48.5 is required for normal cardiovascular function and lens development in zebrafish embryos
    • Cheng S., Shakespeare T., Mui R., White T. W. and Valdimarsson G. (2004) Connexin 48.5 is required for normal cardiovascular function and lens development in zebrafish embryos. J. Biol. Chem. 279: 36993-37003
    • (2004) J. Biol. Chem. , vol.279 , pp. 36993-37003
    • Cheng, S.1    Shakespeare, T.2    Mui, R.3    White, T.W.4    Valdimarsson, G.5
  • 67
    • 0032557404 scopus 로고    scopus 로고
    • The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development
    • Söhl G., Degen J., Teubner B. and Willecke K. (1998) The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development. FEBS Lett. 428: 27-31
    • (1998) FEBS Lett. , vol.428 , pp. 27-31
    • Söhl, G.1    Degen, J.2    Teubner, B.3    Willecke, K.4
  • 68
    • 9444275416 scopus 로고    scopus 로고
    • The novel mouse connexin39 gene is expressed in developing striated muscle fibers
    • Maltzahn J. von, Euwens C., Willecke K. and Söhl G. (2004) The novel mouse connexin39 gene is expressed in developing striated muscle fibers. J. Cell Sci. 117: 5381-5392
    • (2004) J. Cell Sci. , vol.117 , pp. 5381-5392
    • Von Maltzahn, J.1    Euwens, C.2    Willecke, K.3    Söhl, G.4
  • 70
    • 7544239811 scopus 로고    scopus 로고
    • Cloning and functional expression of invertebrate connexins from Halocynthia pyriformis
    • White T. W., Wang H., Mui R., Litteral J. and Brink P. R. (2004) Cloning and functional expression of invertebrate connexins from Halocynthia pyriformis. FEBS Lett. 577: 42-48
    • (2004) FEBS Lett. , vol.577 , pp. 42-48
    • White, T.W.1    Wang, H.2    Mui, R.3    Litteral, J.4    Brink, P.R.5
  • 71
    • 14144251257 scopus 로고    scopus 로고
    • The pattern of intron loss
    • USA
    • Roy S. W. and Gilbert W. (2005) The pattern of intron loss. Proc. Natl. Acad. Sci USA 102: 713-718
    • (2005) Proc. Natl. Acad. Sci , vol.102 , pp. 713-718
    • Roy, S.W.1    Gilbert, W.2
  • 73
    • 0038303289 scopus 로고    scopus 로고
    • A genomewide survey of developmentally relevant genes in Ciona intestinalis. X. Genes for cell junctions and extracellular matrix
    • Sasakura Y., Shoguchi E., Takatori N., Wada S., Meinertzhagen I. A., Satou Y. et al. (2003) A genomewide survey of developmentally relevant genes in Ciona intestinalis. X. Genes for cell junctions and extracellular matrix. Dev. Genes Evol. 213: 303-313
    • (2003) Dev. Genes Evol. , vol.213 , pp. 303-313
    • Sasakura, Y.1    Shoguchi, E.2    Takatori, N.3    Wada, S.4    Meinertzhagen, I.A.5    Satou, Y.6
  • 76
    • 1542563409 scopus 로고    scopus 로고
    • Initial sequencing and comparative analysis of the mouse genome
    • Mouse Genome Sequencing Consortium (2002) Initial sequencing and comparative analysis of the mouse genome. Nature 420: 520-562
    • (2002) Nature , vol.420 , pp. 520-562
  • 77
    • 0025838007 scopus 로고
    • Mouse connexin37: Cloning and functional expression of a gap junction gene highly expressed in lung
    • Willecke K., Heynkes R., Dahl E., Stutenkemper R., Hennemann H., Jungbluth S. et al. (1991) Mouse connexin37: cloning and functional expression of a gap junction gene highly expressed in lung. J. Cell Biol. 114: 1049-1057
    • (1991) J. Cell Biol. , vol.114 , pp. 1049-1057
    • Willecke, K.1    Heynkes, R.2    Dahl, E.3    Stutenkemper, R.4    Hennemann, H.5    Jungbluth, S.6
  • 78
    • 0029165445 scopus 로고
    • Molecular cloning, tissue distribution, and hormonal control in the ovary of Cx41 mRNA, a novel Xenopus connexin gene transcript
    • Yoshizaki G. and Patiño R. (1995) Molecular cloning, tissue distribution, and hormonal control in the ovary of Cx41 mRNA, a novel Xenopus connexin gene transcript. Mol. Reprod. Dev. 42: 7-18
    • (1995) Mol. Reprod. Dev. , vol.42 , pp. 7-18
    • Yoshizaki, G.1    Patiño, R.2
  • 79
    • 0032190086 scopus 로고    scopus 로고
    • Cloning and expression of two related connexins from the perch retina define a distinct subgroup of the connexin family
    • O'Brien J., Bruzzone R., White T. W., Al-Ubaidi M. R. and Ripps H. (1998) Cloning and expression of two related connexins from the perch retina define a distinct subgroup of the connexin family. J. Neurosci. 18: 7625-7637
    • (1998) J. Neurosci. , vol.18 , pp. 7625-7637
    • O'Brien, J.1    Bruzzone, R.2    White, T.W.3    Al-Ubaidi, M.R.4    Ripps, H.5
  • 81
    • 27644452820 scopus 로고    scopus 로고
    • Statistical distributions of optimal global alignment scores of random protein sequences
    • Pang H., Tang J., Chen S. S. and Tao S. (2005) Statistical distributions of optimal global alignment scores of random protein sequences. BMC Bioinform. 6: 257
    • (2005) BMC Bioinform. , vol.6 , pp. 257
    • Pang, H.1    Tang, J.2    Chen, S.S.3    Tao, S.4
  • 82
    • 0025034641 scopus 로고
    • Modulation of gap junction transcript and protein expression during pregnancy in the rat
    • Risek B., Guthrie S., Kumar N. and Gilula N. B. (1990) Modulation of gap junction transcript and protein expression during pregnancy in the rat. J. Cell Biol. 110: 269-282
    • (1990) J. Cell Biol. , vol.110 , pp. 269-282
    • Risek, B.1    Guthrie, S.2    Kumar, N.3    Gilula, N.B.4
  • 83
    • 0026541187 scopus 로고
    • Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping
    • Haefliger J.-A., Bruzzone R., Jenkins N. A., Gilbert D. J., Copeland N. G. and Paul D. L. (1992) Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. J. Biol. Chem. 267: 2057-2064
    • (1992) J. Biol. Chem. , vol.267 , pp. 2057-2064
    • Haefliger, J.-A.1    Bruzzone, R.2    Jenkins, N.A.3    Gilbert, D.J.4    Copeland, N.G.5    Paul, D.L.6
  • 84
    • 0032580152 scopus 로고    scopus 로고
    • A molecular timescale for vertebrate evolution
    • Kumar S. and Hedges S. B. (1998) A molecular timescale for vertebrate evolution. Nature 392: 917-920
    • (1998) Nature , vol.392 , pp. 917-920
    • Kumar, S.1    Hedges, S.B.2
  • 86
    • 0034924068 scopus 로고    scopus 로고
    • The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development
    • Söhl G., Eiberger J., Jung Y. T., Kozak C. A. and Willecke K. (2001) The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development. Biol. Chem. 382: 973-978
    • (2001) Biol. Chem. , vol.382 , pp. 973-978
    • Söhl, G.1    Eiberger, J.2    Jung, Y.T.3    Kozak, C.A.4    Willecke, K.5
  • 87
    • 0025796856 scopus 로고
    • The human connexin gene family of gap junction proteins: Distinct chromosomal locations but similar structures
    • Fishman G. I., Eddy R. L., Shows T. B., Rosenthal L. and Leinwand L. A. (1991) The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. Genomics 10: 250-256
    • (1991) Genomics , vol.10 , pp. 250-256
    • Fishman, G.I.1    Eddy, R.L.2    Shows, T.B.3    Rosenthal, L.4    Leinwand, L.A.5
  • 88
    • 10644283823 scopus 로고    scopus 로고
    • Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
    • Hillier L. W., Miller W., Birney E., Warren W., Hardison R. C., Ponting C. P. et al. (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695-716
    • (2004) Nature , vol.432 , pp. 695-716
    • Hillier, L.W.1    Miller, W.2    Birney, E.3    Warren, W.4    Hardison, R.C.5    Ponting, C.P.6
  • 89
    • 0037162885 scopus 로고    scopus 로고
    • Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes
    • Aparicio S., Chapman J., Stupka E., Putnam N., Chia J. M., Dehal P. et al. (2002) Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science 297: 1301-1310
    • (2002) Science , vol.297 , pp. 1301-1310
    • Aparicio, S.1    Chapman, J.2    Stupka, E.3    Putnam, N.4    Chia, J.M.5    Dehal, P.6
  • 90
    • 7244259101 scopus 로고    scopus 로고
    • Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate protokaryotype
    • Jaillon O., Aury J. M., Brunet F., Petit J. L., Stange-Thomann N., Mauceli E. et al. (2004) Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate protokaryotype. Nature 431: 946-957
    • (2004) Nature , vol.431 , pp. 946-957
    • Jaillon, O.1    Aury, J.M.2    Brunet, F.3    Petit, J.L.4    Stange-Thomann, N.5    Mauceli, E.6
  • 91
    • 0037351989 scopus 로고    scopus 로고
    • Genome duplication, a trait shared by 22000 species of ray-finned fish
    • Taylor J. S., Braasch I., Frickey T., Meyer A. and Van de Peer Y. (2003) Genome duplication, a trait shared by 22000 species of ray-finned fish. Genome Res. 13: 382-390
    • (2003) Genome Res. , vol.13 , pp. 382-390
    • Taylor, J.S.1    Braasch, I.2    Frickey, T.3    Meyer, A.4    Van De Peer, Y.5
  • 92
    • 1242274629 scopus 로고    scopus 로고
    • Major events in the genome evolution of vertebrates: Paranome age and size differ considerably between ray-finned fishes and land vertebrates
    • USA
    • Vandepoele K., De Vos W., Taylor J. S., Meyer A. and Van de Peer Y. (2004) Major events in the genome evolution of vertebrates: paranome age and size differ considerably between ray-finned fishes and land vertebrates. Proc. Natl. Acad. Sci. USA 101: 1638-1643
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 1638-1643
    • Vandepoele, K.1    De Vos, W.2    Taylor, J.S.3    Meyer, A.4    Van De Peer, Y.5
  • 93
    • 30944460666 scopus 로고    scopus 로고
    • Phylogenetic analysis of three complete gap junction gene families reveals lineage-specific duplications and highly supported gene classes
    • Eastman S. D., Chen T. H., Falk M. M., Mendelson T. C. and Iovine M. K. (2006) Phylogenetic analysis of three complete gap junction gene families reveals lineage-specific duplications and highly supported gene classes. Genomics 87: 265-274
    • (2006) Genomics , vol.87 , pp. 265-274
    • Eastman, S.D.1    Chen, T.H.2    Falk, M.M.3    Mendelson, T.C.4    Iovine, M.K.5
  • 94
    • 0032530408 scopus 로고    scopus 로고
    • Molecular markers for cell types of the inner ear and candidate genes for hearing disorders
    • USA
    • Heller S., Sheane C. A., Javed Z. and Hudspeth A. J. (1998) Molecular markers for cell types of the inner ear and candidate genes for hearing disorders. Proc. Natl. Acad. Sci. USA 95: 11400-11405
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 11400-11405
    • Heller, S.1    Sheane, C.A.2    Javed, Z.3    Hudspeth, A.J.4
  • 95
    • 11844278340 scopus 로고    scopus 로고
    • Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins
    • Iovine M. K., Higgins E. P., Hindes A., Coblitz B. and Johnson S. L. (2005) Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins. Dev. Biol. 278: 208-219
    • (2005) Dev. Biol. , vol.278 , pp. 208-219
    • Iovine, M.K.1    Higgins, E.P.2    Hindes, A.3    Coblitz, B.4    Johnson, S.L.5
  • 97
    • 0037242398 scopus 로고    scopus 로고
    • Multiple connexins contribute to intercellular communication in the Xenopus embryo
    • Landesman Y., Postma F. R., Goodenough D. A. and Paul D. L. (2003) Multiple connexins contribute to intercellular communication in the Xenopus embryo. J. Cell Sci. 116: 29-38
    • (2003) J. Cell Sci. , vol.116 , pp. 29-38
    • Landesman, Y.1    Postma, F.R.2    Goodenough, D.A.3    Paul, D.L.4
  • 98
    • 1542605260 scopus 로고    scopus 로고
    • Cloning and expression pattern of connexin39, a new member of the gap junction gene family isolated from the neural tube of chicken embryos
    • Cicirata F., Nicotra A., Cicero D., Parenti R. and Zappalà A. (2004) Cloning and expression pattern of connexin39, a new member of the gap junction gene family isolated from the neural tube of chicken embryos. Gene 328: 121-126
    • (2004) Gene , vol.328 , pp. 121-126
    • Cicirata, F.1    Nicotra, A.2    Cicero, D.3    Parenti, R.4    Zappalà, A.5
  • 99
    • 0032108936 scopus 로고    scopus 로고
    • Expression of major gap junction connexin types in the working myocardium of eight chordates
    • Becker D. L., Cook J. E., Davies C. S., Evans W. H. and Gourdie R. G. (1998) Expression of major gap junction connexin types in the working myocardium of eight chordates. Cell Biol. Int. 22: 527-543
    • (1998) Cell Biol. Int. , vol.22 , pp. 527-543
    • Becker, D.L.1    Cook, J.E.2    Davies, C.S.3    Evans, W.H.4    Gourdie, R.G.5
  • 100
    • 2242464840 scopus 로고    scopus 로고
    • The draft genome of Ciona intestinalis: Insights into chordate and vertebrate origins
    • Dehal P., Satou Y., Campbell R. K., Chapman J., Degnan B., De Tomaso A. et al. (2002) The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science 298: 2157-2167
    • (2002) Science , vol.298 , pp. 2157-2167
    • Dehal, P.1    Satou, Y.2    Campbell, R.K.3    Chapman, J.4    Degnan, B.5    De Tomaso, A.6
  • 101
    • 25144484748 scopus 로고    scopus 로고
    • Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes
    • Okamura Y., Nishino A., Murata Y., Nakajo K., Iwasaki H., Ohtsuka Y. et al. (2005) Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Physiol. Genom. 22: 269-282
    • (2005) Physiol. Genom. , vol.22 , pp. 269-282
    • Okamura, Y.1    Nishino, A.2    Murata, Y.3    Nakajo, K.4    Iwasaki, H.5    Ohtsuka, Y.6
  • 102
    • 0036613509 scopus 로고    scopus 로고
    • Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution
    • Gu X., Wang Y. and Gu J. (2002) Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution. Nat. Genet. 31: 205-209
    • (2002) Nat. Genet. , vol.31 , pp. 205-209
    • Gu, X.1    Wang, Y.2    Gu, J.3
  • 103
    • 0038817812 scopus 로고    scopus 로고
    • New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes
    • Panopoulou G., Hennig S., Groth D., Krause A., Poustka A. J., Herwig R. et al. (2003) New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes. Genome Res. 13: 1056-1066
    • (2003) Genome Res. , vol.13 , pp. 1056-1066
    • Panopoulou, G.1    Hennig, S.2    Groth, D.3    Krause, A.4    Poustka, A.J.5    Herwig, R.6
  • 104
    • 0037075039 scopus 로고    scopus 로고
    • Secret life of genes
    • Theissen G. (2002) Secret life of genes. Nature 415: 741
    • (2002) Nature , vol.415 , pp. 741
    • Theissen, G.1
  • 105
    • 3242810318 scopus 로고    scopus 로고
    • MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
    • Kumar S., Tamura K. and Nei M. (2004) MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief. Bioinform. 5: 150-163
    • (2004) Brief. Bioinform. , vol.5 , pp. 150-163
    • Kumar, S.1    Tamura, K.2    Nei, M.3


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