메뉴 건너뛰기




Volumn 90, Issue 1, 2014, Pages

Differential incubation temperatures result in dimorphic DNA methylation patterning of the SOX9 and aromatase promoters in gonads of alligator (Alligator mississippiensis) embryos

Author keywords

Alligator; Aromatase; DNA methylation; Sex determination; SOX9; Temperature dependent sex determination

Indexed keywords

AROMATASE; GENOMIC DNA; TRANSCRIPTION FACTOR SOX9;

EID: 84899942485     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.111468     Document Type: Article
Times cited : (81)

References (61)
  • 1
    • 0036794474 scopus 로고    scopus 로고
    • Vertebrate sex determination: many means to an end
    • Morrish B, Sinclair A. Vertebrate sex determination: many means to an end. Reproduction 2002; 124:447-457.
    • (2002) Reproduction , vol.124 , pp. 447-457
    • Morrish, B.1    Sinclair, A.2
  • 2
    • 0003416686 scopus 로고
    • Evolution of Sex Determining Mechanism
    • Menlo Park, CA: Benjamin/Cummings
    • Bull JJ. Evolution of Sex Determining Mechanisms. Menlo Park, CA: Benjamin/Cummings; 1983
    • (1983)
    • Bull, J.J.1
  • 3
    • 0037150614 scopus 로고    scopus 로고
    • Sex determination and sex differentiation in fish: an overview of genetic, physiological and environmental influences
    • Devlin RH, Nagahama Y. Sex determination and sex differentiation in fish: an overview of genetic, physiological and environmental influences. Aquaculture 2002; 208:191-364.
    • (2002) Aquaculture , vol.208 , pp. 191-364
    • Devlin, R.H.1    Nagahama, Y.2
  • 4
    • 64649090979 scopus 로고    scopus 로고
    • Analyzing the coordinated gene network underlying temperature-dependent sex determination in reptiles
    • Shoemaker CM, Crews D. Analyzing the coordinated gene network underlying temperature-dependent sex determination in reptiles. Semin Cell Dev Biol 2009; 20:293-303.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 293-303
    • Shoemaker, C.M.1    Crews, D.2
  • 5
    • 0019974904 scopus 로고
    • Temperature of egg incubation determines sex in Alligator mississippiensis
    • Ferguson MWJ, Joanen T. Temperature of egg incubation determines sex in Alligator mississippiensis. Nature 1982; 296:850-852.
    • (1982) Nature , vol.296 , pp. 850-852
    • Ferguson, M.W.J.1    Joanen, T.2
  • 6
    • 84993918848 scopus 로고
    • Temperature-dependent sex determination in crocodilians
    • Lang JW, Andrews HV. Temperature-dependent sex determination in crocodilians. J Exp Zool 1994; 270:28-44.
    • (1994) J Exp Zool , vol.270 , pp. 28-44
    • Lang, J.W.1    Andrews, H.V.2
  • 7
    • 0000491433 scopus 로고
    • Gonadal development and differentiation in Alligator mississippiensis at male and female producing incubation temperatures
    • Joss JMP. Gonadal development and differentiation in Alligator mississippiensis at male and female producing incubation temperatures. Journal of Zoology 1989; 218:679-687.
    • (1989) Journal of Zoology , vol.218 , pp. 679-687
    • Joss, J.M.P.1
  • 8
    • 0029000990 scopus 로고
    • Aromatase enzyme activity during gonadal sex differentiation in alligator embryos
    • Smith CA, Elf PK, Lang JW, Joss JMP. Aromatase enzyme activity during gonadal sex differentiation in alligator embryos. Differentiation 1995; 58: 281-290.
    • (1995) Differentiation , vol.58 , pp. 281-290
    • Smith, C.A.1    Elf, P.K.2    Lang, J.W.3    Joss, J.M.P.4
  • 9
    • 0032739889 scopus 로고    scopus 로고
    • Temperature-dependent sex determination in the American alligator: AMH precedes SOX9 expression
    • Western PS, Harry JL, Graves JAM, Sinclair AH. Temperature-dependent sex determination in the American alligator: AMH precedes SOX9 expression. Dev Dyn 1999; 216:411-419.
    • (1999) Dev Dyn , vol.216 , pp. 411-419
    • Western, P.S.1    Harry, J.L.2    Graves, J.A.M.3    Sinclair, A.H.4
  • 10
    • 0017785807 scopus 로고
    • Anti-Mullerian hormone is a functional marker of foetal Sertoli cells
    • Tran D, Muesy-Dessole N, Josso N. Anti-Mullerian hormone is a functional marker of foetal Sertoli cells. Nature 1977; 269:411-412.
    • (1977) Nature , vol.269 , pp. 411-412
    • Tran, D.1    Muesy-Dessole, N.2    Josso, N.3
  • 11
    • 0029742909 scopus 로고    scopus 로고
    • Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
    • Morais da Silva S, Hacker A, Harley V, Goodfellow P, Swain A, Lovell- Badge R. Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat Genet 1996; 14:62-68.
    • (1996) Nat Genet , vol.14 , pp. 62-68
    • Morais da Silva, S.1    Hacker, A.2    Harley, V.3    Goodfellow, P.4    Swain, A.5    Lovell-Badge, R.6
  • 12
    • 0032979117 scopus 로고    scopus 로고
    • Temperature-dependent sex determination: upregulation of SOX9 expression after commitment to male development
    • Western PS, Harry JL, Graves JA, Sinclair AH. Temperature-dependent sex determination: upregulation of SOX9 expression after commitment to male development. Dev Dyn 1999; 214:171-177.
    • (1999) Dev Dyn , vol.214 , pp. 171-177
    • Western, P.S.1    Harry, J.L.2    Graves, J.A.3    Sinclair, A.H.4
  • 13
    • 0000009634 scopus 로고
    • Problems of fetal endocrinology: the gonadal and hypophyseal hormones
    • Jost A. Problems of fetal endocrinology: the gonadal and hypophyseal hormones. Recent Prog Horm Res 1953; 8:379-418.
    • (1953) Recent Prog Horm Res , vol.8 , pp. 379-418
    • Jost, A.1
  • 14
    • 0344946482 scopus 로고    scopus 로고
    • AMH/MIS: what we know already about the gene, the protein and its regulation
    • Rey R, Lukas-Croisier C, Lasala C, Bedecarras P. AMH/MIS: what we know already about the gene, the protein and its regulation. Mol Cell Endocrinol 2003; 211:21-31.
    • (2003) Mol Cell Endocrinol , vol.211 , pp. 21-31
    • Rey, R.1    Lukas-Croisier, C.2    Lasala, C.3    Bedecarras, P.4
  • 18
    • 45149093155 scopus 로고    scopus 로고
    • Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
    • Sekido R, Lovell-Badge R. Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer. Nature 2008; 453:930-934.
    • (2008) Nature , vol.453 , pp. 930-934
    • Sekido, R.1    Lovell-Badge, R.2
  • 20
    • 0032972214 scopus 로고    scopus 로고
    • Temperature-dependent sex determination and gonadal differentiation in reptiles
    • Pieau C, Dorizzi M, Richard-Mercier N. Temperature-dependent sex determination and gonadal differentiation in reptiles. Cell Mol Life Sci 1999; 55:887-900.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 887-900
    • Pieau, C.1    Dorizzi, M.2    Richard-Mercier, N.3
  • 21
    • 0023946122 scopus 로고
    • Sex reversal by estradiol in three reptilian orders
    • Bull JJ, Gutzke, WHN, Crews D. Sex reversal by estradiol in three reptilian orders. Gen Comp Endocrinol 1988; 70:425-428.
    • (1988) Gen Comp Endocrinol , vol.70 , pp. 425-428
    • Bull, J.J.1    Gutzke, W.H.N.2    Crews, D.3
  • 22
    • 1042279662 scopus 로고    scopus 로고
    • Sex determination: insights from the chicken
    • Smith CA, Sinclair AH. Sex determination: insights from the chicken. Bioessays 2004; 26:120-132.
    • (2004) Bioessays , vol.26 , pp. 120-132
    • Smith, C.A.1    Sinclair, A.H.2
  • 23
    • 0020975412 scopus 로고
    • Effects and role of estrogens in avian gonadal differentiation
    • Scheib D. Effects and role of estrogens in avian gonadal differentiation. Differentiation 1983; 23:S87-92.
    • (1983) Differentiation , vol.23
    • Scheib, D.1
  • 24
    • 0030879591 scopus 로고    scopus 로고
    • Alteration in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants
    • Crain DA, Guillette LJ Jr, Rooney AA, Pickford DB. Alteration in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants. Environ Health Perspec 1997; 105:528-533.
    • (1997) Environ Health Perspec , vol.105 , pp. 528-533
    • Crain, D.A.1    Guillette Jr., L.J.2    Rooney, A.A.3    Pickford, D.B.4
  • 25
    • 0036075387 scopus 로고    scopus 로고
    • Effects of incubation temperature and estrogen exposure on aromatase activity in the brain and gonads of embryonic alligators
    • Milnes MR, Roberts R, Guillette LJ Jr. Effects of incubation temperature and estrogen exposure on aromatase activity in the brain and gonads of embryonic alligators. Environ Health Perspec 2002; 110(suppl. 3): 393-396.
    • (2002) Environ Health Perspec , vol.110 , Issue.SUPPL. 3 , pp. 393-396
    • Milnes, M.R.1    Roberts, R.2    Guillette Jr., L.J.3
  • 26
    • 0035884020 scopus 로고    scopus 로고
    • Alligator aromatase cDNA sequence and its expression in embryos at male and female incubation temperatures
    • Gabriel WN, Blumberg B, Sutton S, Place AR, Lance VA. Alligator aromatase cDNA sequence and its expression in embryos at male and female incubation temperatures. J Exp Zool 2001; 290:439-448.
    • (2001) J Exp Zool , vol.290 , pp. 439-448
    • Gabriel, W.N.1    Blumberg, B.2    Sutton, S.3    Place, A.R.4    Lance, V.A.5
  • 27
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate PH, Bird AP. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opinion Genet Dev 1993; 3:226-231.
    • (1993) Curr Opinion Genet Dev , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 28
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, Schubeler D. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39: 457-466.
    • (2007) Nat Genet , vol.39 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Paabo, S.5    Rebhan, M.6    Schubeler, D.7
  • 29
    • 0037007175 scopus 로고    scopus 로고
    • Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases
    • Jeltsch A. Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases. Chembiochem 2002; 3:274-293.
    • (2002) Chembiochem , vol.3 , pp. 274-293
    • Jeltsch, A.1
  • 30
    • 38449104412 scopus 로고    scopus 로고
    • On the enzymatic properties of Dnmt1: specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme
    • Jeltsch A. On the enzymatic properties of Dnmt1: specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme. Epigenetics 2006; 1:63-66.
    • (2006) Epigenetics , vol.1 , pp. 63-66
    • Jeltsch, A.1
  • 31
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001; 293:1068-1070.
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 32
    • 82355183876 scopus 로고    scopus 로고
    • On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2
    • Jurkowski TP, Jeltsch A. On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2. Plos One 2011; 6:e28104.
    • (2011) Plos One , vol.6
    • Jurkowski, T.P.1    Jeltsch, A.2
  • 33
    • 84869228439 scopus 로고    scopus 로고
    • Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion
    • Ellis HL, Shioda K, Rosenthal NF, Coser KR, Shioda T. Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion. Biol Reprod 2012; 87(23):21-12.
    • (2012) Biol Reprod , vol.87 , Issue.23 , pp. 12-21
    • Ellis, H.L.1    Shioda, K.2    Rosenthal, N.F.3    Coser, K.R.4    Shioda, T.5
  • 35
    • 79958769174 scopus 로고    scopus 로고
    • Methylation status of cMHM and expression of sex-specific genes in adult sex-reversed female chickens
    • Yang X, Zheng J, Qu L, Chen S, Li J, Xu G, Yang N. Methylation status of cMHM and expression of sex-specific genes in adult sex-reversed female chickens. Sex Dev 2011; 5:147-154.
    • (2011) Sex Dev , vol.5 , pp. 147-154
    • Yang, X.1    Zheng, J.2    Qu, L.3    Chen, S.4    Li, J.5    Xu, G.6    Yang, N.7
  • 36
    • 84878769335 scopus 로고    scopus 로고
    • Epigenetic control of gonadal aromatase (cyp19a1) in temperature-dependent sex determination of red-eared slider turtles
    • Matsumoto Y, Buemio A, Chu R, Vafaee M, Crews D. Epigenetic control of gonadal aromatase (cyp19a1) in temperature-dependent sex determination of red-eared slider turtles. Plos One 2013; 8:e63599.
    • (2013) Plos One , vol.8
    • Matsumoto, Y.1    Buemio, A.2    Chu, R.3    Vafaee, M.4    Crews, D.5
  • 37
    • 1642421836 scopus 로고    scopus 로고
    • Evidence of gender- and tissue-specific promoter methylation and the potential for ethinylestradiolinduced changes in Japanese medaka (Oryzias latipes) estrogen receptor and aromatase genes
    • Contractor RG, Foran CM, Li S, Willett KL. Evidence of gender- and tissue-specific promoter methylation and the potential for ethinylestradiolinduced changes in Japanese medaka (Oryzias latipes) estrogen receptor and aromatase genes. J Toxicol Environ Health 2004; 67:1-22.
    • (2004) J Toxicol Environ Health , vol.67 , pp. 1-22
    • Contractor, R.G.1    Foran, C.M.2    Li, S.3    Willett, K.L.4
  • 38
    • 84855296910 scopus 로고    scopus 로고
    • DNA methylation of the gonadal aromatase (cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European sea bass
    • Navarro-Martin L, Vinas J, Ribas L, Diaz N, Gutierrez A, Di Croce L, Piferrer F. DNA methylation of the gonadal aromatase (cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European sea bass. PLoS Genetics 2011; 7:e1002447.
    • (2011) PLoS Genetics , vol.7
    • Navarro-Martin, L.1    Vinas, J.2    Ribas, L.3    Diaz, N.4    Gutierrez, A.5    Di Croce, L.6    Piferrer, F.7
  • 39
    • 0000967461 scopus 로고
    • Reproductive biology and embryology of the crocodilians
    • Gans C, Billet, F Maderson P (eds.), New York: J. Wiley and Sons
    • Ferguson MWJ. Reproductive biology and embryology of the crocodilians In: Gans C, Billet, F Maderson P (eds.), Biology of the Reptilia, Vol. 14. New York: J. Wiley and Sons; 1985; 329-491.
    • (1985) Biology of the Reptilia , vol.14 , pp. 329-491
    • Ferguson, M.W.J.1
  • 40
    • 77949875598 scopus 로고    scopus 로고
    • Potential contributions of heat shock proteins to temperature-dependent sex determination in the American alligator
    • Kohno S, Katsu Y, Urushitani H, Ohta Y, Iguchi T, Guillette JLJ. Potential contributions of heat shock proteins to temperature-dependent sex determination in the American alligator. Sex Dev 2010; 4:73-87.
    • (2010) Sex Dev , vol.4 , pp. 73-87
    • Kohno, S.1    Katsu, Y.2    Urushitani, H.3    Ohta, Y.4    Iguchi, T.5    Guillette, J.L.J.6
  • 41
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 42
    • 27744577751 scopus 로고    scopus 로고
    • BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
    • Bock C, Reither S, Mikeska T, Paulsen M, Walter J, Lengauer T. BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics 2005; 21:4067-4068.
    • (2005) Bioinformatics , vol.21 , pp. 4067-4068
    • Bock, C.1    Reither, S.2    Mikeska, T.3    Paulsen, M.4    Walter, J.5    Lengauer, T.6
  • 44
    • 0037108159 scopus 로고    scopus 로고
    • The RNA polymerase II core promoter: a key component in the regulation of gene expression
    • Butler JE, Kadonaga JT. The RNA polymerase II core promoter: a key component in the regulation of gene expression. Genes Dev 2002; 16: 2583-2592.
    • (2002) Genes Dev , vol.16 , pp. 2583-2592
    • Butler, J.E.1    Kadonaga, J.T.2
  • 45
    • 0023216891 scopus 로고
    • CpG Islands in vertebrate genomes
    • Gardiner-Garden M, Frommer M. CpG Islands in vertebrate genomes. J Mol Biol 1987; 196:261-282.
    • (1987) J Mol Biol , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 46
    • 0142063462 scopus 로고    scopus 로고
    • Evolution of dioecy and sex chromosomes via methylation driving Muller's ratchet
    • Gorelick R. Evolution of dioecy and sex chromosomes via methylation driving Muller's ratchet. Biol J Linn Soc Lond 2003; 80:353-368.
    • (2003) Biol J Linn Soc Lond , vol.80 , pp. 353-368
    • Gorelick, R.1
  • 49
    • 84878729685 scopus 로고    scopus 로고
    • The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan
    • Wang Z, Pascual-Anaya J, Zadissa A, Li W, Niimura Y, Huang Z, Li C, White S, Xiong Z, Fang D, Wang B, Ming Y, et al. The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan. Nat Genet 2013; 45: 701-706.
    • (2013) Nat Genet , vol.45 , pp. 701-706
    • Wang, Z.1    Pascual-Anaya, J.2    Zadissa, A.3    Li, W.4    Niimura, Y.5    Huang, Z.6    Li, C.7    White, S.8    Xiong, Z.9    Fang, D.10    Wang, B.11    Ming, Y.12
  • 50
    • 0032145035 scopus 로고    scopus 로고
    • Sequence and expression analysis of WT1 and Sox9 in the red-eared slider turtle, Trachemys scripta
    • Spotila LD, Spotila JR, Hall SE. Sequence and expression analysis of WT1 and Sox9 in the red-eared slider turtle, Trachemys scripta. J Exp Zool 1998; 281:417-427.
    • (1998) J Exp Zool , vol.281 , pp. 417-427
    • Spotila, L.D.1    Spotila, J.R.2    Hall, S.E.3
  • 51
    • 34247345849 scopus 로고    scopus 로고
    • Expression of Sox9, Mis, and Dmrt1 in the gonad of a species with temperature-dependent sex determination
    • Shoemaker C, Ramsey M, Queen J, Crews D. Expression of Sox9, Mis, and Dmrt1 in the gonad of a species with temperature-dependent sex determination. Dev Dyn 2007; 236:1055-1063.
    • (2007) Dev Dyn , vol.236 , pp. 1055-1063
    • Shoemaker, C.1    Ramsey, M.2    Queen, J.3    Crews, D.4
  • 52
    • 77951228439 scopus 로고    scopus 로고
    • Estrogen represses SOX9 during sex determination in the red-eared slider turtle Trachemys scripta
    • Barske LA, Capel B. Estrogen represses SOX9 during sex determination in the red-eared slider turtle Trachemys scripta. Dev Biol 2010; 341: 305-314.
    • (2010) Dev Biol , vol.341 , pp. 305-314
    • Barske, L.A.1    Capel, B.2
  • 53
    • 68149101449 scopus 로고    scopus 로고
    • Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain
    • Agrawal R, Wessely O, Anand A, Singh L, Aggarwal RK. Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain. FEBS J 2009; 276:4184-4196.
    • (2009) FEBS J , vol.276 , pp. 4184-4196
    • Agrawal, R.1    Wessely, O.2    Anand, A.3    Singh, L.4    Aggarwal, R.K.5
  • 54
    • 42949150151 scopus 로고    scopus 로고
    • Five azacytidine, a DNA methyltransferase inhibitor, specifically inhibits testicular cord formation and Sertoli cell differentiation in vitro
    • Mizukami T, Kanai Y, Fujisawa M, Kanai-Azuma M, Kurohmaru M, Hayashi Y. Five azacytidine, a DNA methyltransferase inhibitor, specifically inhibits testicular cord formation and Sertoli cell differentiation in vitro. Mol Reprod Dev 2008; 75:1002-1010.
    • (2008) Mol Reprod Dev , vol.75 , pp. 1002-1010
    • Mizukami, T.1    Kanai, Y.2    Fujisawa, M.3    Kanai-Azuma, M.4    Kurohmaru, M.5    Hayashi, Y.6
  • 55
    • 84866773269 scopus 로고    scopus 로고
    • Life in a contaminated world
    • Guillette LJ, Iguchi T. Life in a contaminated world. Science 2012; 337: 1614-1615.
    • (2012) Science , vol.337 , pp. 1614-1615
    • Guillette, L.J.1    Iguchi, T.2
  • 56
    • 79952786671 scopus 로고    scopus 로고
    • Embryos as targets of endocrine disrupting contaminants in wildlife
    • Hamlin HJ, Guillette LJ Jr. Embryos as targets of endocrine disrupting contaminants in wildlife. Birth Defects Res C Embryo Today 2011; 93: 19-33.
    • (2011) Birth Defects Res C Embryo Today , vol.93 , pp. 19-33
    • Hamlin, H.J.1    Guillette Jr., L.J.2
  • 57
    • 0028129515 scopus 로고
    • Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida
    • Guillette LJ Jr, Gross TS, Masson GR, Matter JM, Percival HF, Woodward AR. Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ Health Perspec 1994; 102:680-688.
    • (1994) Environ Health Perspec , vol.102 , pp. 680-688
    • Guillette Jr., L.J.1    Gross, T.S.2    Masson, G.R.3    Matter, J.M.4    Percival, H.F.5    Woodward, A.R.6
  • 58
    • 77950343521 scopus 로고    scopus 로고
    • Influences of sex, incubation temperature, and environmental quality on gonadal estrogen and androgen receptor messenger RNA expression in juvenile American alligators (Alligator mississippiensis)
    • Moore BC, Milnes MR, Kohno S, Katsu Y, Iguchi T, Guillette LJ Jr. Influences of sex, incubation temperature, and environmental quality on gonadal estrogen and androgen receptor messenger RNA expression in juvenile American alligators (Alligator mississippiensis). Biol Reprod 2010; 82:194-201.
    • (2010) Biol Reprod , vol.82 , pp. 194-201
    • Moore, B.C.1    Milnes, M.R.2    Kohno, S.3    Katsu, Y.4    Iguchi, T.5    Guillette Jr., L.J.6
  • 59
    • 43249114644 scopus 로고    scopus 로고
    • Increased posthatching mortality and loss of sexually dimorphic gene expression in alligators (Alligator mississippiensis) from a contaminated environment
    • Milnes MR, Bryan TA, Katsu Y, Kohno S, Moore BC, Iguchi T, Guillette LJ Jr. Increased posthatching mortality and loss of sexually dimorphic gene expression in alligators (Alligator mississippiensis) from a contaminated environment. Biol Reprod 2008; 78:932-938.
    • (2008) Biol Reprod , vol.78 , pp. 932-938
    • Milnes, M.R.1    Bryan, T.A.2    Katsu, Y.3    Kohno, S.4    Moore, B.C.5    Iguchi, T.6    Guillette Jr., L.J.7
  • 60
    • 77951027748 scopus 로고    scopus 로고
    • Altered sex hormone concentrations and gonadal mRNA expression levels of activin signaling factors in hatchling alligators from a contaminated Florida lake
    • Moore BC, Kohno S, Cook RW, Alvers AL, Hamlin HJ, Woodruff TK, Guillette LJ. Altered sex hormone concentrations and gonadal mRNA expression levels of activin signaling factors in hatchling alligators from a contaminated Florida lake. J Exp Zool 2010; 313:218-230.
    • (2010) J Exp Zool , vol.313 , pp. 218-230
    • Moore, B.C.1    Kohno, S.2    Cook, R.W.3    Alvers, A.L.4    Hamlin, H.J.5    Woodruff, T.K.6    Guillette, L.J.7
  • 61
    • 84858298436 scopus 로고    scopus 로고
    • Geneenvironment interactions: the potential role of contaminants in somatic growth and the development of the reproductive system of the American alligator
    • Moore BC, Roark AM, Kohno S, Hamlin HJ, Guillette LJ, Jr. Geneenvironment interactions: the potential role of contaminants in somatic growth and the development of the reproductive system of the American alligator. Mol Cell Endocrinol 2012; 354:111-120.
    • (2012) Mol Cell Endocrinol , vol.354 , pp. 111-120
    • Moore, B.C.1    Roark, A.M.2    Kohno, S.3    Hamlin, H.J.4    Guillette Jr., L.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.