Five azacytidine, a DNA methyltransferase inhibitor, specifically inhibits testicular cord formation and Sertoli cell differentiation in vitro

Molecular Reproduction and Development

Volumn 75, Issue 6, 2008, Pages 1002-1010

  Mizukami, Takuo ^a   Kanai, Yoshiakira ^a   Fujisawa, Masahiko ^a   Kanai Azuma, Masami ^b   Kurohmaru, Masamichi ^a   Hayashi, Yoshihiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 azacytidine; Col9a3; DNA methylation; Sex determination; Testis

Indexed keywords

AZACITIDINE; DNA; DNA METHYLTRANSFERASE INHIBITOR; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; DNA METHYLTRANSFERASE; ENZYME INHIBITOR; HIGH MOBILITY GROUP PROTEIN; HOMEODOMAIN PROTEIN; LHX9 PROTEIN, MOUSE; MEMBRANE ANTIGEN; MFGE8 PROTEIN, MOUSE; MILK PROTEIN; SOX-9 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA METHYLATION; DOSE RESPONSE; FEMALE; GENE EXPRESSION; GONAD DEVELOPMENT; IN SITU HYBRIDIZATION; IN VITRO STUDY; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SERTOLI CELL; SEX DETERMINATION; TESTIS DEVELOPMENT; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; ORGAN CULTURE TECHNIQUE; OVARY; PRENATAL DEVELOPMENT; STROMA CELL; TESTIS;

MAMMALIA;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ANTIGENS, SURFACE; AZACITIDINE; CELL DIFFERENTIATION; DNA METHYLATION; DNA MODIFICATION METHYLASES; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIGH MOBILITY GROUP PROTEINS; HOMEODOMAIN PROTEINS; LEYDIG CELLS; MALE; MICE; MICE, INBRED ICR; MILK PROTEINS; ORGAN CULTURE TECHNIQUES; OVARY; SERTOLI CELLS; STROMAL CELLS; TESTIS; TRANSCRIPTION FACTORS;

EID: 42949150151     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.20850     Document Type: Article

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