Investigation of drug-polymer interaction in solid dispersions by vapour sorption methods

International Journal of Pharmaceutics

Volumn 469, Issue 1, 2014, Pages 159-167

  Punčochová, Kateřina ^a,c   Heng, Jerry Y Y ^b   Beránek, Josef ^c   Štěpánek, František ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Zentiva Ks ^*  (Czech Republic)

Author keywords

Dissolution rate; Drug polymer interaction; Hydrogen bond; Solid dispersion; Spray drying; Water sorption

Indexed keywords

POLYMER; VALSARTAN; EUDRAGIT E PO; MACROGOL DERIVATIVE; POLYMETHACRYLIC ACID DERIVATIVE; POLYVINYL CAPROLACTAM-POLYVINYL ACETATE-POLYETHYLENE GLYCOL GRAFT COPOLYMER; POLYVINYL DERIVATIVE; POVIDONE; TETRAZOLE DERIVATIVE; VALINE; WATER;

ANALYTIC METHOD; ARTICLE; ATTENUATED TOTAL REFLECTANCE FOURIER TRANSFORM INFRARED SPECTROSCOPY; CONTROLLED STUDY; DRUG FORMULATION; DRUG RESEARCH; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; INFRARED SPECTROSCOPY; ISOTHERM; LIGHT SCATTERING; MOLECULAR INTERACTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLID DISPERSION; SPRAY DRYING; VAPOR SORPTION METHOD; WATER VAPOR; X RAY DIFFRACTION; ADSORPTION; ANALOGS AND DERIVATIVES; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; HYDROGEN BOND; KINETICS; PHARMACEUTICS; PROCEDURES; SOLUBILITY; VOLATILIZATION; X RAY CRYSTALLOGRAPHY;

ADSORPTION; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; POLYMERS; POLYMETHACRYLIC ACIDS; POLYVINYLS; POVIDONE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TETRAZOLES; VALINE; VALSARTAN; VOLATILIZATION; WATER;

EID: 84899938812     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.048     Document Type: Article

References (20)

1. M.A. Alam, R. Ali, F.I. Al-Jenoobi, and A.M. Al-Mohizea Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates Expert Opinion Drug Delivery 9 2012 1419 1440
2. M. Chang, A.S. Myerson, and T.K. Kwei The effect of hydrogen bonding on vapour diffusion in water-soluble polymers Journal of Applied Polymer Science 66 1997 279 291 (Pubitemid 127596003)
3. H.R. Constantino, J.G. Curley, S. Wu, and C.C. Hsu Water sorption behaviour of lyophilised proteinsugar systems and implications for solid-state interactions International Journal of Pharmaceutics 166 1998 211 221 (Pubitemid 28255228)
4. D.Q.M. Craig The mechanisms of drug release from solid dispersions in water-soluble polymers International Journal of Pharmaceutics 231 2002 131 144 (Pubitemid 34033673)
5. D.Q.M. Craig, and J.M. Newton The dissolution of nortriptyline HCl from polyethylene glycol solid dispersion International Journal of Pharmaceutics 78 1992 175 182
6. K.J. Crowley, and G. Zografi Water vapour absorption into amorphous hydrophobic drug/poly(vinylpyrrolidone) dispersions Journal of Pharmaceutical Sciences 91 2002 2150 2158
7. K. Dhirendra, S. Lewis, N. Udupa, and K. Atin Solid dispersion: a review Pakistan Journal of Pharmaceutical Sciences 22 2009 234 246
8. F. Frizon, J.O. Eloy, C.M. Donaduzzi, M.L. Mitsui, and J.M. Marchetti Dissolution rate enhancement of loratadine in polyvinylpyrrolidone K-30 solid dispersions by solvent methods Powder Technology 235 2013 532 539
9. J.Y.Y. Heng, D.F. Pearse, D.A. Wilson, and D.R. Williams Characterization of solid state materials using vapour sorption methods Solid State Characterization of Pharmaceuticals 1st ed. 2006 Pergamon Poland Chapter 13, pp. 449-492
10. S. Kachel, P. Scharfel, and W. Schabel Sorption isotherms of mixtures of polymers, proteins and electrolytes - measurement data and modell predictions Chemical Engineering and Processing: Process Intensification 68 2013 45 54
11. C. Knox, V. Law, T. Jewison, P. Liu, S. Ly, A. Frolkis, A. Pon, K. Banco, C. Mak, V. Neveu, Y. Djoumbou, R. Eisner, A.C. Guo, and D.S. Wishart DrugBank 3.0: a comprehensive resource for 'omics' research on drugs Nucleic Acids Research 39 2011 D1035 D1041 (Database issue)
12. +) correlations of IR spectroscopic and structural data Spectrochimica Acta Part A 62 2005 1196 1202
13. A.E. Reed, L.A. Curtiss, and F. Weingold Intermolecular interactions from a natural bond orbital, donoracceptor viewpoint American Chemical Society 88 1988 899 926
14. A.C.F. Rumondor Effect of polymer hygroscopicity on the phase behaviour of amorphous solid dispersions in the presence of moisture Molecular Pharmaceutics 7 2009 477 490
15. Li Y. Sanzgiri, Y.D. Chen, and Y A study on moisture isotherms of formulations: the use of polynomial equations to predict the moisture isotherms of tablet products AAPS PharmSciTech 4 2003 1 8
16. A. Serajuddin Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs Journal of Pharmaceutical Sciences 88 1999 1058 1066
17. S.L. Shamblin, B.C. Hancock, and G. Zografi Water vapour sorption by peptides, proteins and their formulations European Journal of Pharmaceutics and Biopharmaceutics 45 1998 239 247 (Pubitemid 28270812)
18. L.S. Taylor, F.W. Langkilde, and G. Zografi Fourier transform Raman spectroscopic study of the interaction of water vapour with amorphous polymers Journal of Pharmaceutical Sciences 90 2001 888 901 (Pubitemid 32645946)
19. L.S. Taylor Spectroscopic characterization of interactions between PVP and indomethacin in amorphous moleculae dispersions Pharmaceutical Research 14 1997 1691 1698 (Pubitemid 28062912)
20. J. Zhang, and G. Zografi Water vapour absorption into amorphous sucrose-poly(vinyl pyrrolidone) and trehalose-poly(vinyl pyrrolidone) mixtures Journal of Pharmaceutical Sciences 90 2001 1375 1385 (Pubitemid 32867986)