Physical inactivity and muscle oxidative capacity in humans

European Journal of Sport Science

Volumn 14, Issue 4, 2014, Pages 376-383

  Gram, Martin ^a   Dahl, Rannvá ^a   Dela, Flemming ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

human; oxidative capacity; Physical inactivity; skeletal muscle

Indexed keywords

ENZYME; PROTEIN;

EXERCISE; GENE EXPRESSION; HUMAN; METABOLISM; MUSCLE MITOCHONDRION; OXIDATIVE STRESS; PHYSIOLOGY; SKELETAL MUSCLE;

ENZYMES; EXERCISE; GENE EXPRESSION; HUMANS; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; OXIDATIVE STRESS; PROTEINS;

EID: 84899921821     PISSN: 17461391     EISSN: 15367290     Source Type: Journal    
DOI: 10.1080/17461391.2013.823466     Document Type: Review

References (41)

1. Abadi, A., Glover, E. I., Isfort, R. J., Raha, S., Safdar, A., Yasuda, N., Tarnopolsky, M. (2009). Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women. PLoS One, 4, e6518. doi:10.1371/journal.pone.0006518
2. Alibegovic, A. C., Sonne, M. P., Hojbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Vaag, A. (2010). Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men. American Journal of Physiology - Endocrinology and Metabolism, 299, E752-E763. doi:10.1152/ajpendo.00590.2009
3. Biolo, G., Agostini, F., Simunic, B., Sturma, M., Torelli, L., Preiser, J. C., Narici, M. V. (2008). Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest. American Journal of Clinical Nutrition, 88, 950-958.
4. Blair, S. N., Kampert, J. B., Kohl, H. W. III, Barlow, C. E., Macera, C. A., Paffenbarger, R. S., & Gibbons, L. W Jr. (1996). Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women. Journal of the American Medical Association, 276(3), 205-210. doi:10.1001/jama.1996.03540030039029
5. Blakemore, S. J., Rickhuss, P. K., Watt, P. W., Rennie, M. J., & Hundal, H. S. (1996). Effects of limb immobilization on cytochrome c oxidase activity and GLUT4 and GLUT5 protein expression in human skeletal muscle. Clinical Sciences Laboratory, 91, 591-599.
6. Bosutti, A., Malaponte, G., Zanetti, M., Castellino, P., Heer, M., Guarnieri, G., & Biolo, G. (2008). Calorie restriction modulates inactivity-induced changes in the inflammatory markers C-reactive protein and pentraxin-3. Journal of Clinical Endocrinology & Metabolism, 93, 3226-3229. doi:10.1210/jc.2007-1684
7. Bradley, S. J., Kingwell, B. A., & McConell, G. K. (1999). Nitric oxide synthase inhibition reduces leg glucose uptake but not blood flow during dynamic exercise in humans. Diabetes, 48(9), 1815-1821. doi:10.2337/diabetes.48.9.1815
8. Brand, M. D. (2010). The sites and topology of mitochondrial superoxide production. Experimental Gerontology, 45, 466-472. doi:10.1016/j.exger.2010.01.003
9. Brocca, L., Cannavino, J., Coletto, L., Biolo, G., Sandri, M., Bottinelli, R., & Pellegrino, M. A. (2012). The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms. The Journal of Physiology, 590(20), 5211-5230. doi:10.1113/jphysiol.2012.240267
10. Brown, G. C., & Borutaite, V. (2012). There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells. Mitochondrion, 12, 1-4. doi:10.1016/j.mito.2011.02.001
11. Castro, M. J., Apple, D. F., Jr., Staron, R. S., Campos, G. E., & Dudley, G. A. (2000). Influence of complete spinal cord injury on skeletal muscle within 6 month of injury. Journal of Applied Physiology, 86, 350-358.
12. Dalla, L. L., Ravara, B., Gobbo, V., Tarricone, E., Vitadello, M., Biolo, G., Gorza, L. (2009). A transient antioxidant stress response accompanies the onset of disuse atrophy in human skeletal muscle. Journal of Applied Physiology, 107, 549-557. doi:10.1152/japplphysiol.00280.2009
13. Edgerton, V. R., Zhou, M. Y., Ohira, Y., Klitgaard, H., Jiang, B., Bell, G., Roy, R. R. (1995). Human fiber size and enzymatic properties after 5 and 11 days of spaceflight. Journal of Applied Physiology, 78, 1733-1739.
14. Ferretti, G., Antonutto, G., Denis, C., Hoppeler, H., Minetti, A. E., Narici, M. V., & Desplanches, D. (1997). The interplay of central and peripheral factors in limiting maximal O2 consumption in man after prolonged bed rest. Journal of Physiology, 501(Pt 3), 677-686. doi:10.1111/j.1469-7793.1997.677bm.x
15. Friedrichsen, M., Ribel-Madsen, R., Mortensen, B., Hansen, C. N., Alibegovic, A. C., Hojbjerre, L., Vaag, A. (2012). Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared with normal birth weight. European Journal of Endocrinology, 167, 829-838. doi:10.1530/EJE-12-0498
16. Glover, E. I., Yasuda, N., Tarnopolsky, M. A., Abadi, A., & Phillips, S. M. (2010). Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophy. Applied Physiology Nutrition and Metabolism, 35, 125-133. doi:10.1139/H09-137
17. Hackney, K. J., & Ploutz-Snyder, L. L. (2012). Unilateral lower limb suspension: Integrative physiological knowledge from the past 20 years (1991-2011). European Journal of Applied Physiology, 112, 9-22. doi:10.1007/s00421-011-1971-7
18. Haggmark, T., Jansson, E., & Eriksson, E. (1981). Fiber type area and metabolic potential of the thigh muscle in man after knee surgery and immobilization. International Journal of Sports Medicine, 2, 12-17. doi:10.1055/s-2008-1034577
19. Hamburg, N. M., McMackin, C. J., Huang, A. L., Shenouda, S. M., Widlansky, M. E., Schulz, E., Vita, J. A. (2007). Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arteriosclerosis, Thrombosis, and Vascular Biology, 27, 2650-2656. doi:10.1161/ATVBAHA.107.153288
20. Hather, B. M., Adams, G. R., Tesch, P. A., & Dudley, G. A. (1992). Skeletal muscle responses to lower limb suspension in humans. Journal of Applied Physiology, 72, 1493-1498.
21. Hikida, R. S., Gollnick, P. D., Dudley, G. A., Convertino, V. A., & Buchanan, P. (1989). Structural and metabolic characteristics of human skeletal muscle following 30 days of simulated microgravity. Aviation Space & Environmental Medicine, 60, 664-670.
22. Jansson, E., Sylven, C., Arvidsson, I., & Eriksson, E. (1988). Increase in myoglobin content and decrease in oxidative enzyme activities by leg muscle immobilization in man. Acta Physiologica Scandinavica, 132, 515-517. doi:10.1111/j.1748-1716.1988.tb08358.x
23. Laaksonen, D. E., Lindstrom, J., Lakka, T. A., Eriksson, J. G., Niskanen, L., Wikstrom, K., Uusitupa, M. (2005). Physical activity in the prevention of type 2 diabetes: The Finnish diabetes prevention study. Diabetes, 54(1), 158-165. doi:10.2337/diabetes.54.1.158
24. Larsen, S., Nielsen, J., Hansen, C. N., Nielsen, L. B., Wibrand, F., Stride, N., Hey-Mogensen, M. (2012). Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects. The Journal of Physiology, 590(14), 3349-3360. doi:10.1113/jphysiol.2012.230185
25. Levine, S., Nguyen, T., Taylor, N., Friscia, M. E., Budak, M. T., Rothenberg, P., Shrager, J. B. (2008). Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. The New England Journal of Medicine, 358, 1327-1335.
26. Mazzucco, S., Agostini, F., & Biolo, G. (2010). Inactivity-mediated insulin resistance is associated with upregulated pro-inflammatory fatty acids in human cell membranes. Clinical Nutrition, 29, 386-390.
27. Moriggi, M., Vasso, M., Fania, C., Capitanio, D., Bonifacio, G., Salanova, M., Gelfi, C. (2010). Long term bed rest with and without vibration exercise countermeasures: Effects on human muscle protein dysregulation. Proteomics, 10, 3756-3774.
28. Mujika, I., & Padilla, S. (2001). Muscular characteristics of detraining in humans. Medicine & Science in Sports & Exercise, 33, 1297-1303.
29. Nielsen, J., Suetta, C., Hvid, L. G., Schroder, H. D., Aagaard, P., & Ortenblad, N. (2010). Subcellular localization-dependent decrements in skeletal muscle glycogen and mitochondria content following short-term disuse in young and old men. American Journal of Physiology - Endocrinology and Metabolism, 299, E1053-E1060.
30. Powers, S. K., Smuder, A. J., & Judge, A. R. (2012). Oxidative stress and disuse muscle atrophy: Cause or consequence? Current Opinion in Clinical Nutrition and Metabolic Care, 15, 240-245.
31. Powers, S. K., Wiggs, M. P., Duarte, J. A., Zergeroglu, A. M., & Demirel, H. A. (2012). Mitochondrial signaling contributes to disuse muscle atrophy. American Journal of Physiology - Endocrinology and Metabolism, 303, E31-E39.
32. Richter, E. A., Kiens, B., Mizuno, M., & Strange, S. (1989). Insulin action in human thighs after one-legged immobilization. Journal of Applied Physiology, 67, 19-23.
33. Ringholm, S., Bienso, R. S., Kiilerich, K., Guadalupe-Grau, A., Aachmann-Andersen, N. J., Saltin, B., Pilegaard, H. (2011). Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle. American Journal of Physiology - Endocrinology and Metabolism, 301, E649-E658.
34. Rudnick, J., Puttmann, B., Tesch, P. A., Alkner, B., Schoser, B. G., Salanova, M., Blottner, D. (2004). Differential expression of nitric oxide synthases (NOS 1-3) in human skeletal muscle following exercise countermeasure during 12 weeks of bed rest. FASEB Journal, 18, 1228-1230.
35. Salanova, M., Schiffl, G., Puttmann, B., Schoser, B. G., & Blottner, D. (2008). Molecular biomarkers monitoring human skeletal muscle fibres and microvasculature following long-term bed rest with and without countermeasures. Journal of Anatomy, 212, 306-318.
36. Tesch, P. A., Berg, H. E., Haggmark, T., Ohlsen, H., & Dudley, G. A. (1991). Muscle strength and endurance following lowerlimb suspension in man. Physiologist, 34, S104-S106.
37. Timmons, J. A., Norrbom, J., Schéele, C., Thonberg, H., Wahlestedt, C., & Tesch, P. (2006). Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes. Genomics, 87(1), 165-172.
38. Traon, A. P. L., Heer, M., Narici, M. V., Rittweger, J., & Vernikos, J. (2007). From space to Earth: Advances in human physiology from 20 years of bed rest studies (1986-2006). European Journal of Applied Physiology, 101(2), 143-194. doi:10.1007/s00421-007-0474-z.
39. Vescovo, G., Ravara, B., & Dalla, L. L. (2008). Skeletal muscle myofibrillar protein oxidation and exercise capacity in heart failure. Basic Research in Cardiology, 103, 285-290.
40. Wei, M., Gibbons, L. W., Kampert, J. B., Nichaman, M. Z., & Blair, S. N. (2000). Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes. Annals of Internal Medicine, 132, 605-611.
41. World Health Organisation. (2012). Prevalence of insufficient physical activity. Retrieved from http://www.who.int/gho/ncd/risk_factors/physical_activity/en/