Multi-stage laccase extraction and separation using aqueous two-phase systems: Experiment and model

Process Biochemistry

Volumn 49, Issue 6, 2014, Pages 1020-1031

  Prinz, Axel ^a   Koch, Katharina ^a   Górak, Andrzej ^a,b   Zeiner, Tim ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Aqueous two phase extraction; Equilibrium stage modeling; Laccase; Multi stage experiments; Scale up

Indexed keywords

EXPERIMENTS; SOLVENT EXTRACTION;

AQUEOUS TWO-PHASE EXTRACTION; EQUILIBRIUM-STAGE-MODELING; LACCASES; MULTI-STAGE; SCALE-UP;

ENZYMES;

EID: 84899910656     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2014.03.011     Document Type: Article

References (23)

1. S.M. Cramer, and M.A. Holstein Downstream bioprocessing: recent advances and future promise: open issue 1/1 Curr Opin Chem Eng 1 1 2011 27 37
2. P. Albertsson Partition of cell particles and macromolecules 3rd ed. 1986 John Wiley & Sons New York
3. K.H. Kroner, H. Hustedt, S. Granda, and M.R. Kula Technical aspects of separation using aqueous two-phase systems in enzyme isolation processes Biotechnol Bioeng 20 12 1978 1967 1988
4. M.R. Kula Extraction and purification of enzymes using aqueous two-phase systems Appl Biochem Bioeng 2 1979 71 95
5. H. Hustedt, K.H. Kroner, U. Menge, and M. Kula Protein recovery using two-phase systems Trends Biotechnol 3 6 1985 139 144
6. P.A.J. Rosa, A.M. Azevedo, S. Sommerfeld, M. Mutter, M.R. Aires-Barros, and W. Bäcker Application of aqueous two-phase systems to antibody purification: a multi-stage approach J Biotechnol 139 4 2009 306 313
7. P.A.J. Rosa, A.M. Azevedo, S. Sommerfeld, M. Mutter, W. Bäcker, and M.R. Aires-Barros Continuous purification of antibodies from cell culture supernatant with aqueous two-phase systems: from concept to process Biotechnol J 8 3 2013 352 362
8. P.A.J. Rosa, A.M. Azevedo, S. Sommerfeld, W. Bäcker, and M.R. Aires-Barros Continuous aqueous two-phase extraction of human antibodies using a packed column J Chromatogr B: Anal Technol Biomed Life Sci 880 1 2012 148 156
9. B.Y. Zaslavsky Aqueous two-phase partitioning: physical chemistry and bioanalytical applications 1995 Dekker New York, NY
10. H. Walter, D. Fisher, and D.E. Brooks Partitioning in aqueous two-phase systems: theory, methods, uses, and applications to biotechnology 1985 Academic Press Orlando
11. S.L. Mistry, J.A. Asenjo, and C.A. Zaror Mathematical modelling and simulation of aqueous two-phase continuous protein extraction Bioseparation 3 6 1992 343 358
12. S.L. Mistry, A. Kaul, J.C. Merchuk, and J.A. Asenjo Mathematical modelling and computer simulation of aqueous two-phase continuous protein extraction J Chromatogr A 741 2 1996 151 163
13. M.M. Ahmad, S. Hauan, and T.M. Przybycien Flowsheet simulation of aqueous two-phase extraction systems for protein purification J Chem Technol Biotechnol 85 12 2010 1575 1587
14. M.M. Ahmad, and T.M. Przybycien Towards optimal aqueous two-phase extraction system flowsheets for protein purification J Chem Technol Biotechnol 88 1 2013 62 71
15. J.A. Samatou, A.E. Wentink, J. Alexandra, P. Rosa, A. Margarida Azevedo, and M. Raquel Aires Barros et al. Modeling of counter current monoclonal antibody extraction using aqueous two-phase systems Comput Aided Chem Eng 24 2007 935 940
16. D. Linke, H. Bouws, T. Peters, M. Nimtz, R.G. Berger, and H. Zorn Laccases of Pleurotus sapidus: characterization and cloning J Agric Food Chem 53 24 2005 9498 9505
17. A. Majcherczyk, C. Johannes, and A. Hüttermann Oxidation of aromatic alcohols by laccase from Trametes versicolor mediated by the 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) cation radical and dication Appl Microbiol Biotechnol 51 2 1999 267 276
18. A. Prinz, J. Hönig, I. Schüttmann, H. Zorn, and T. Zeiner Separation and purification of laccases from two different fungi using aqueous two-phase extraction Process Biochem 49 2014 335 346
19. P.K. Smith, R.I. Krohn, G.T. Hermanson, A.K. Mallia, F.H. Gartner, and M.D. Provenzano Measurement of protein using bicinchoninic acid Anal Biochem 150 1 1985 76 85
20. J.A. Asenjo Separation processes in biotechnology M.W. Courtney, Bioprocess technology 1990 Dekker New York, NY
21. H. Cabezas Theory of phase formation in aqueous two-phase systems J Chromatogr B: Biomed Sci Appl 680 1 1996 3 30
22. F.M. Khoury Multistage separation processes 3rd ed. 2005 CRC Press Boca Raton
23. D.F. Othmer, and P.E. Tobias Liquid-liquid extraction data - toluene and acetaldehyde systems Ind Eng Chem Res 34 6 1942 690 692