Influence of additives on a thermosensitive hydrogel for buccal delivery of salbutamol: Relation between micellization, gelation, mechanic and release properties

International Journal of Pharmaceutics

Volumn 467, Issue 1-2, 2014, Pages 70-83

  Zeng, Ni ^a,b   Dumortier, Gilles ^a   Maury, Marc ^b   Mignet, Nathalie ^a   Boudy, Vincent ^a,c  

^a Centre National de la Recherche Scientifique   (France)

^b Unither Développement Bordeaux   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Drug release; Flow through cell (USP 4 apparatus); Mathematical modeling; NaCl; Poloxamer; Xanthan gum

Indexed keywords

SALBUTAMOL; XANTHAN; ARTIFICIAL MEMBRANE; BACTERIAL POLYSACCHARIDE; DRUG CARRIER; HYDROGEL; MICELLE; POLOXAMER; SODIUM CHLORIDE;

ARTICLE; CHEEK MUCOSA; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; EROSION; GELATION; HYDROGEL; MICELLIZATION; PRIORITY JOURNAL; TEMPERATURE; ADHESION; ARTIFICIAL MEMBRANE; BUCCAL DRUG ADMINISTRATION; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; KINETICS; MEDICINAL CHEMISTRY; MICELLE; PHARMACEUTICS; PROCEDURES; SOLUBILITY; TENSILE STRENGTH; VISCOSITY;

ADHESIVENESS; ADMINISTRATION, BUCCAL; ALBUTEROL; CHEMISTRY, PHARMACEUTICAL; DIFFUSION; DRUG CARRIERS; HYDROGELS; KINETICS; MEMBRANES, ARTIFICIAL; MICELLES; MODELS, CHEMICAL; POLOXAMER; POLYSACCHARIDES, BACTERIAL; SODIUM CHLORIDE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; TENSILE STRENGTH; VISCOSITY;

EID: 84899897486     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.03.055     Document Type: Article

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