-
1
-
-
46249104490
-
Systematic meta-analyses and feld synopsis of genetic association studies in schizophrenia: The SzGene database
-
Allen NC, Bagade S, McQueen MB, et al. Systematic meta-analyses and feld synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet. 2008;40:827-834.
-
(2008)
Nat Genet.
, vol.40
, pp. 827-834
-
-
Allen, N.C.1
Bagade, S.2
McQueen, M.B.3
-
2
-
-
67651180973
-
A genome-wide association study in 574 schizophrenia trios using DNA pooling
-
Kirov G, Zaharieva I, Georgieva L, et al. A genome-wide association study in 574 schizophrenia trios using DNA pooling. Mol Psychiatry. 2009;14:796-803.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 796-803
-
-
Kirov, G.1
Zaharieva, I.2
Georgieva, L.3
-
3
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-752.
-
(2009)
Nature.
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
-
4
-
-
82255175590
-
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
-
Shi Y, Li Z, Xu Q, et al. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet. 2011;43:1224-1227.
-
(2011)
Nat Genet.
, vol.43
, pp. 1224-1227
-
-
Shi, Y.1
Li, Z.2
Xu, Q.3
-
5
-
-
80053384370
-
Genome-wide association study identifes fve new schizophrenia loci
-
Schizophrenia Psychiatric Genome-Wide Association Study Consortium.
-
Schizophrenia Psychiatric Genome-Wide Association Study Consortium. Genome-wide association study identifes fve new schizophrenia loci. Nat Genet. 2011;43:969-976.
-
(2011)
Nat Genet.
, vol.43
, pp. 969-976
-
-
-
6
-
-
82255175589
-
Genome-wide association study identifes a susceptibility locus for schizophrenia in Han Chinese at 11p11.2
-
Yue WH, Wang HF, Sun LD, et al. Genome-wide association study identifes a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet. 2011;43:1228-1231.
-
(2011)
Nat Genet.
, vol.43
, pp. 1228-1231
-
-
Yue, W.H.1
Wang, H.F.2
Sun, L.D.3
-
7
-
-
84863247591
-
Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specifc bone mineral density
-
Xiao SM, Kung AW, Gao Y, et al. Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specifc bone mineral density. Hum Mol Genet. 2012;21:1648-1657.
-
(2012)
Hum Mol Genet.
, vol.21
, pp. 1648-1657
-
-
Xiao, S.M.1
Kung, A.W.2
Gao, Y.3
-
8
-
-
84863173053
-
A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits
-
Guo Y, Tomlinson B, Chu T, et al. A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits. PLoS One. 2012;7:e31489.
-
(2012)
PLoS One.
, vol.7
-
-
Guo, Y.1
Tomlinson, B.2
Chu, T.3
-
9
-
-
82955188800
-
Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection
-
Chan KY, Wong CM, Kwan JS, et al. Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection. PLoS One. 2011;6:e28798.
-
(2011)
PLoS One.
, vol.6
-
-
Chan, K.Y.1
Wong, C.M.2
Kwan, J.S.3
-
10
-
-
33746512512
-
Principal components analysis corrects for stratifcation in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratifcation in genome-wide association studies. Nat Genet. 2006;38:904-909.
-
(2006)
Nat Genet.
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
11
-
-
67651222400
-
A fexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie BN, Donnelly P, Marchini J. A fexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 2009;5:e1000529.
-
(2009)
PLoS Genet.
, vol.5
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
12
-
-
77953441375
-
Sex chromosomes and genetic association studies
-
Clayton DG. Sex chromosomes and genetic association studies. Genome Med. 2009;1:110.
-
(2009)
Genome Med.
, vol.1
, pp. 110
-
-
Clayton, D.G.1
-
13
-
-
52449118475
-
Testing for association on the X chromosome
-
Clayton D. Testing for association on the X chromosome. Biostatistics. 2008;9:593-600.
-
(2008)
Biostatistics.
, vol.9
, pp. 593-600
-
-
Clayton, D.1
-
14
-
-
79952467494
-
GATES: A rapid and powerful gene-based association test using extended Simes procedure
-
Li MX, Gui HS, Kwan JS, Sham PC. GATES: a rapid and powerful gene-based association test using extended Simes procedure. Am J Hum Genet. 2011;88:283-293.
-
(2011)
Am J Hum Genet.
, vol.88
, pp. 283-293
-
-
Li, M.X.1
Gui, H.S.2
Kwan, J.S.3
Sham, P.C.4
-
15
-
-
80053385384
-
Large-scale genome-wide association analysis of bipolar disorder identifes a new susceptibility locus near ODZ4
-
Psychiatric GWAS Consortium Bipolar Disorder Worki ng Group.
-
Psychiatric GWAS Consortium Bipolar Disorder Worki ng Group. Large-scale genome-wide association analysis of bipolar disorder identifes a new susceptibility locus near ODZ4. Nat Genet. 2011;43:977-983.
-
(2011)
Nat Genet.
, vol.43
, pp. 977-983
-
-
-
16
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81:559-575.
-
(2007)
Am J Hum Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
17
-
-
84878219255
-
Evaluating risk loci for schizophrenia distilled from genome-wide association studies in Han Chinese from central China
-
Ma L, Tang J, Wang D, et al. Evaluating risk loci for schizophrenia distilled from genome-wide association studies in Han Chinese from central China. Mol Psychiatry. 2011;18:638-639.
-
(2011)
Mol Psychiatry
, vol.18
, pp. 638-639
-
-
Ma, L.1
Tang, J.2
Wang, D.3
-
18
-
-
84878228205
-
Genetic evidence for association between NOTCH4 and schizophrenia supported by a GWAS follow-up study in a Japanese population
-
Ikeda M, Aleksic B, Yamada K, et al. Genetic evidence for association between NOTCH4 and schizophrenia supported by a GWAS follow-up study in a Japanese population. Mol Psychiatry. 2013;18:636-638.
-
(2013)
Mol Psychiatry
, vol.18
, pp. 636-638
-
-
Ikeda, M.1
Aleksic, B.2
Yamada, K.3
-
19
-
-
0344305525
-
Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies
-
Sullivan PF, Kendler KS, Neale MC Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry. 2003;60:1187-1192.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 1187-1192
-
-
Sullivan, P.F.1
Kendler, K.S.2
Neale, M.C.3
-
21
-
-
58149464318
-
Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
-
Lichtenstein P, Yip BH, Björk C, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet. 2009;373:234-239.
-
(2009)
Lancet.
, vol.373
, pp. 234-239
-
-
Lichtenstein, P.1
Yip, B.H.2
Björk, C.3
-
22
-
-
57749191950
-
Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is associated with schizophrenia in a Spanish population
-
Crescenti A, Gassó P, Mas S, et al. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is associated with schizophrenia in a Spanish population. Psychiatry Res. 2009;165:175-180.
-
(2009)
Psychiatry Res.
, vol.165
, pp. 175-180
-
-
Crescenti, A.1
Gassó, P.2
Mas, S.3
-
23
-
-
75149194357
-
Angiotensin-converting enzyme polymorphism in schizophrenia, bipolar disorders, and their frst-degree relatives
-
Kucukali CI, Aydin M, Ozkok E, et al. Angiotensin-converting enzyme polymorphism in schizophrenia, bipolar disorders, and their frst-degree relatives. Psychiatr Genet. 2010;20:14-19.
-
(2010)
Psychiatr Genet.
, vol.20
, pp. 14-19
-
-
Kucukali, C.I.1
Aydin, M.2
Ozkok, E.3
-
24
-
-
0030012832
-
Interactions of angiotensin II with central dopamine
-
Jenkins TA, Allen AM, Chai SY, MacGregor DP, Paxinos G, Mendelsohn FA. Interactions of angiotensin II with central dopamine. Adv Exp Med Biol. 1996;396:93-103.
-
(1996)
Adv Exp Med Biol.
, vol.396
, pp. 93-103
-
-
Jenkins, T.A.1
Allen, A.M.2
Chai, S.Y.3
MacGregor, D.P.4
Paxinos, G.5
Mendelsohn, F.A.6
-
25
-
-
0031027898
-
Angiotensin-converting enzyme modulates dopamine turnover in the striatum
-
Jenkins TA, Mendelsohn FA, Chai SY Angiotensin-converting enzyme modulates dopamine turnover in the striatum. J Neurochem. 1997;68:1304-1311.
-
(1997)
J Neurochem.
, vol.68
, pp. 1304-1311
-
-
Jenkins, T.A.1
Mendelsohn, F.A.2
Chai, S.Y.3
-
26
-
-
2342655011
-
The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
-
Wright JW, Harding JW The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory. Prog Neurobiol. 2004;72:263-293.
-
(2004)
Prog Neurobiol.
, vol.72
, pp. 263-293
-
-
Wright, J.W.1
Harding, J.W.2
-
27
-
-
0035880454
-
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry
-
LaSalle JM, Goldstine J, Balmer D, Greco CM. Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry. Hum Mol Genet. 2001;10:1729-1740.
-
(2001)
Hum Mol Genet.
, vol.10
, pp. 1729-1740
-
-
Lasalle, J.M.1
Goldstine, J.2
Balmer, D.3
Greco, C.M.4
-
28
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
Chahrour M, Jung SY, Shaw C, et al. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science. 2008;320:1224-1229.
-
(2008)
Science
, vol.320
, pp. 1224-1229
-
-
Chahrour, M.1
Jung, S.Y.2
Shaw, C.3
-
29
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet. 1999;23:185-188.
-
(1999)
Nat Genet.
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
30
-
-
33746356840
-
Rett syndrome: New clinical and molecular insights
-
Williamson SL, Christodoulou J. Rett syndrome: new clinical and molecular insights. Eur J Hum Genet. 2006;14: 896-903.
-
(2006)
Eur J Hum Genet.
, vol.14
, pp. 896-903
-
-
Williamson, S.L.1
Christodoulou, J.2
-
31
-
-
3042847437
-
MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: A possible association with autism
-
Shibayama A, Cook EH Jr, Feng J, et al. MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism. Am J Med Genet B Neuropsychiatr Genet. 2004;128B:50-53.
-
(2004)
Am J Med Genet B Neuropsychiatr Genet.
, vol.128 B
, pp. 50-53
-
-
Shibayama, A.1
Cook, Jr.E.H.2
Feng, J.3
-
32
-
-
67649921127
-
The genetic landscape of intellectual disability arising from chromosome X
-
Gécz J, Shoubridge C, Corbett M. The genetic landscape of intellectual disability arising from chromosome X. Trends Genet. 2009;25:308-316.
-
(2009)
Trends Genet.
, vol.25
, pp. 308-316
-
-
Gécz, J.1
Shoubridge, C.2
Corbett, M.3
-
33
-
-
0036211908
-
MECP2 mutation in a boy with severe neonatal encephalopathy: Clinical, neuropathological and molecular fndings
-
Geerdink N, Rotteveel JJ, Lammens M, et al. MECP2 mutation in a boy with severe neonatal encephalopathy: clinical, neuropathological and molecular fndings. Neuropediatrics. 2002;33:33-36.
-
(2002)
Neuropediatrics.
, vol.33
, pp. 33-36
-
-
Geerdink, N.1
Rotteveel, J.J.2
Lammens, M.3
-
34
-
-
0036371289
-
MECP2 mutation in a boy with language disorder and schizophrenia
-
Cohen D, Lazar G, Couvert P, et al. MECP2 mutation in a boy with language disorder and schizophrenia. Am J Psychiatry. 2002;159:148-149.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 148-149
-
-
Cohen, D.1
Lazar, G.2
Couvert, P.3
-
35
-
-
70349334689
-
A common MECP2 haplo-type associates with reduced cortical surface area in humans in two independent populations
-
Joyner AH, J CR, Bloss CS, et al. A common MECP2 haplo-type associates with reduced cortical surface area in humans in two independent populations. Proc Natl Acad Sci U S A. 2009;106:15483-15488.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, pp. 15483-15488
-
-
Joyner, A.H.1
Cr, J.2
Bloss, C.S.3
-
36
-
-
84873906337
-
Anatomical abnormalities in gray and white matter of the cortical surface in persons with schizophrenia
-
Colibazzi T, Wexler BE, Bansal R, et al. Anatomical abnormalities in gray and white matter of the cortical surface in persons with schizophrenia. PLoS One. 2013;8:e55783.
-
(2013)
PLoS One.
, vol.8
-
-
Colibazzi, T.1
Wexler, B.E.2
Bansal, R.3
-
37
-
-
78149431869
-
Dysfunction in GABA signalling mediates autismlike stereotypies and Rett syndrome phenotypes
-
Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J et al. Dysfunction in GABA signalling mediates autismlike stereotypies and Rett syndrome phenotypes. Nature 2010;468:263-269.
-
(2010)
Nature
, vol.468
, pp. 263-269
-
-
Chao, H.T.1
Chen, H.2
Samaco, R.C.3
Xue, M.4
Chahrour, M.5
Yoo, J.6
-
38
-
-
21344438862
-
GABAergic dysfunction in schizophrenia: New treatment strategies on the horizon
-
Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, et al. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology (Berl) 2005;180:191-205.
-
(2005)
Psychopharmacology (Berl)
, vol.180
, pp. 191-205
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
Dong, E.4
Grayson, D.R.5
Veldic, M.6
-
40
-
-
9744273944
-
A GABAergic cortical defcit dominates schizophrenia pathophysiology
-
Costa E, Davis JM, Dong E, Grayson DR, Guidotti A, Tremolizzo L, et al. A GABAergic cortical defcit dominates schizophrenia pathophysiology. Crit Rev Neurobiol 2004;16:1-23.
-
(2004)
Crit Rev Neurobiol
, vol.16
, pp. 1-23
-
-
Costa, E.1
Davis, J.M.2
Dong, E.3
Grayson, D.R.4
Guidotti, A.5
Tremolizzo, L.6
-
41
-
-
80051472149
-
GABAergic interneuron origin of schizophrenia pathophysiology [published online ahead of print 2011]
-
Nakazawa K, Zsiros V, Jiang Z, Nakao K, Kolata S, Zhang S, et al. GABAergic interneuron origin of schizophrenia pathophysiology [published online ahead of print 2011]. Neuropharmacology.
-
Neuropharmacology
-
-
Nakazawa, K.1
Zsiros, V.2
Jiang, Z.3
Nakao, K.4
Kolata, S.5
Zhang, S.6
-
42
-
-
77950565107
-
Cross talk between microRNA and epigenetic regulation in adult neurogenesis
-
Szulwach KE, Li X, Smrt RD, et al. Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J Cell Biol. 2010;189:127-141.
-
(2010)
J Cell Biol.
, vol.189
, pp. 127-141
-
-
Szulwach, K.E.1
Li, X.2
Smrt, R.D.3
-
43
-
-
35448938873
-
ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth
-
Vogt DL, Gray CD, Young WS 3rd, Orellana SA, Malouf AT. ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth. Mol Cell Neurosci. 2007;36:332-342.
-
(2007)
Mol Cell Neurosci.
, vol.36
, pp. 332-342
-
-
Vogt, D.L.1
Gray, C.D.2
Young III, W.S.3
Orellana, S.A.4
Malouf, A.T.5
-
44
-
-
80051584270
-
Possible association between interleukin-1β gene and schizophrenia in a Japanese population
-
Sasayama D, Hori H, Teraishi T, et al. Possible association between interleukin-1β gene and schizophrenia in a Japanese population. Behav Brain Funct. 2011;7:35.
-
(2011)
Behav Brain Funct.
, vol.7
, pp. 35
-
-
Sasayama, D.1
Hori, H.2
Teraishi, T.3
-
45
-
-
70449864112
-
Activation of brain interleukin-1beta in schizophrenia
-
Söderlund J, Schröder J, Nordin C, et al. Activation of brain interleukin-1beta in schizophrenia. Mol Psychiatry. 2009;14:1069-1071.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 1069-1071
-
-
Söderlund, J.1
Schröder, J.2
Nordin, C.3
-
46
-
-
0035890510
-
Cytokine effects on cortical neuron MAP-2 immuno-reactivity: Implications for schizophrenia
-
Marx CE, Jarskog LF, Lauder JM, Lieberman JA, Gilmore JH. Cytokine effects on cortical neuron MAP-2 immuno-reactivity: implications for schizophrenia. Biol Psychiatry. 2001;50:743-749.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 743-749
-
-
Marx, C.E.1
Jarskog, L.F.2
Lauder, J.M.3
Lieberman, J.A.4
Gilmore, J.H.5
-
47
-
-
84866952211
-
Regional cortical thinning in subjects with high genetic loading for schizophrenia
-
Byun MS, Kim JS, Jung WH, et al. Regional cortical thinning in subjects with high genetic loading for schizophrenia. Schizophr Res. 2012;141:197-203.
-
(2012)
Schizophr Res.
, vol.141
, pp. 197-203
-
-
Byun, M.S.1
Kim, J.S.2
Jung, W.H.3
-
48
-
-
82255175590
-
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
-
Shi Y, Li Z, Xu Q, et al. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet. 2011;43:1224-1227.
-
(2011)
Nat Genet.
, vol.43
, pp. 1224-1227
-
-
Shi, Y.1
Li, Z.2
Xu, Q.3
-
49
-
-
82255175589
-
Genome-wide association study identifes a susceptibility locus for schizophrenia in Han Chinese at 11p11.2
-
Yue WH, Wang HF, Sun LD, et al. Genome-wide association study identifes a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet. 2011;43:1228-1231.
-
(2011)
Nat Genet.
, vol.43
, pp. 1228-1231
-
-
Yue, W.H.1
Wang, H.F.2
Sun, L.D.3
-
50
-
-
61449223631
-
Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identifcation of candidate genes, pathways and mechanisms
-
Le-Niculescu H, Patel SD, Bhat M, et al. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identifcation of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet. 2009;150B:155-181.
-
(2009)
Am J Med Genet B Neuropsychiatr Genet.
, vol.150 B
, pp. 155-181
-
-
Le-Niculescu, H.1
Patel, S.D.2
Bhat, M.3
-
51
-
-
77957914573
-
Genome-wide association scan of trait depression
-
Terracciano A, Tanaka T, Sutin AR, et al. Genome-wide association scan of trait depression. Biol Psychiatry. 2010;68:811-817.
-
(2010)
Biol Psychiatry
, vol.68
, pp. 811-817
-
-
Terracciano, A.1
Tanaka, T.2
Sutin, A.R.3
-
52
-
-
77951113131
-
Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder
-
Soria V, Martínez-Amorós E, Escaramís G, et al. Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology. 2010;35:1279-1289.
-
(2010)
Neuropsychopharmacology.
, vol.35
, pp. 1279-1289
-
-
Soria, V.1
Martínez-Amorós, E.2
Escaramís, G.3
|