Integrated redox proteomics and metabolomics of mitochondria to identify mechanisms of Cd toxicity

Toxicological Sciences

Volumn 139, Issue 1, 2014, Pages 59-73

  Go, Young Mi ^a   Roede, James R ^a   Orr, Michael ^a   Liang, Yongliang ^a   Jones, Dean P ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cysteine proteome; Environmental toxicant; Metabolome; Pathway maps; Thiol disulfide redox state

Indexed keywords

ACYLCARNITINE; BRANCHED CHAIN AMINO ACID; CADMIUM; CARNITINE; CYSTEINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; PROTEOME; PRIMER DNA;

ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; FATTY ACID OXIDATION; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MASS SPECTROMETRY; METABOLOMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION STATE; PROTEIN FUNCTION; PROTEOMICS; ANIMAL; C57BL MOUSE; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; TOXICITY;

AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; BASE SEQUENCE; CADMIUM; CHROMATOGRAPHY, LIQUID; DNA PRIMERS; METABOLOMICS; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84899867980     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu018     Document Type: Article

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