Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells

Journal of Leukocyte Biology

Volumn 96, Issue 1, 2014, Pages 151-159

  Martin, Rebecca K ^a   Saleem, Sheinei J ^a   Folgosa, Lauren ^a   Zellner, Hannah B ^a   Damle, Sheela R ^a   Nguyen, Giang Kim T ^a   Ryan, John J ^a   Bear, Harry D ^a,b,c   Irani, Anne Marie ^a   Conrad, Daniel H ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Allergic disease; Cetirizine; Cimetidine; Nippostrongylus brasiliensis; Parasite; Th2

Indexed keywords

CD11B ANTIGEN; CD33 ANTIGEN; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 13;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; IMMUNOREGULATION; IN VITRO STUDY; MAST CELL; MELANOMA B16; METASTASIS; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PARASITE CLEARANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE; TH2 CELL;

ALLERGIC DISEASE; CETIRIZINE; CIMETIDINE; NIPPOSTRONGYLUS BRASILIENSIS; PARASITE; TH2;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; HISTAMINE; HISTAMINE ANTAGONISTS; INTERLEUKIN-13; INTERLEUKIN-4; MAST CELLS; MICE; MICE, MUTANT STRAINS; RECEPTORS, HISTAMINE; TH2 CELLS;

EID: 84899866433     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.5A1213-644R     Document Type: Article

References (51)

1. Gabrilovich, D. I., Nagaraj, S. (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174.
2. Saleem, S. J., Conrad, D. H. (2011) Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion. Int. Immunopharmacol. 11, 808-815.
3. Gabrilovich, D. I., Ostrand-Rosenberg, S., Bronte, V. (2012) Coordinated regulation of myeloid cells by tumours. Nat. Rev. Immunol. 12, 253-268.
4. Goni, O., Alcaide, P., Fresno, M. (2002) Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1(+)CD11b(+) immature myeloid suppressor cells. Int. Immunol. 14, 1125-1134.
5. Guilliams, M., Movahedi, K., Bosschaerts, T., VandenDriessche, T., Chuah, M. K., Herin, M., Acosta-Sanchez, A., Ma, L., Moser, M., Van Ginderachter, J. A., et al. (2009) IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection. J. Immunol. 182, 1107-1118.
6. Narita, Y., Wakita, D., Ohkur, T., Chamoto, K., Nishimura, T. (2009) Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells. Biomed. Res. 30, 7-15.
7. Van Ginderachter, J. A., Beschin, A., De, B. P., Raes, G. (2010) Myeloidderived suppressor cells in parasitic infections. Eur. J. Immunol. 40, 2976-2985.
8. Cuenca, A. G., Delano, M. J., Kelly-Scumpia, K. M., Moreno, C., Scumpia, P. O., LaFace, D. M., Heyworth, P. G., Efron, P. A., Moldawer, L. L. (2011) A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol. Med. 17, 281-292.
9. Saleem, S. J., Martin, R. K., Morales, J. K., Sturgill, J. L., Gibb, D. R., Graham, L., Bear, H. D., Manjili, M. H., Ryan, J. J., Conrad, D. H. (2012) Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity. J. Immunol. 189, 511-515.
10. Huang, B., Lei, Z., Zhang, G. M., Li, D., Song, C., Li, B., Liu, Y., Yuan, Y., Unkeless, J., Xiong, H., et al. (2008) SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood 112, 1269-1279.
11. Miller, H. R. (1996) Mucosal mast cells and the allergic response against nematode parasites. Vet. Immunol. Immunopathol. 54, 331-336.
12. Oldford, S. A., Haidl, I. D., Howatt, M. A., Leiva, C. A., Johnston, B., Marshall, J. S. (2010) A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth. J. Immunol. 185, 7067-7076.
13. Ribatti, D., Crivellato, E. (2009) The controversial role of mast cells in tumor growth. Int. Rev. Cell. Mol. Biol. 275, 89-131.
14. El-Agamy, D. S. (2012) Targeting c-kit in the therapy of mast cell disorders: current update. Eur. J. Pharmacol. 690, 1-3.
15. Elenkov, I. J., Webster, E., Papanicolaou, D. A., Fleisher, T. A., Chrousos, G. P., Wilder, R. L. (1998) Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors. J. Immunol. 161, 2586-2593.
16. Hsu, C. L., Bryce, P. J. (2012) Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway. J. Immunol. 189, 3421-3429.
17. Suzukawa, M., Morita, H., Nambu, A., Arae, K., Shimura, E., Shibui, A., Yamaguchi, S., Suzukawa, K., Nakanishi, W., Oboki, K., et al. (2012) Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. J. Immunol. 189, 3641-3652.
18. Galli, S. J., Tsai, M., Piliponsky, A. M. (2008) The development of allergic inflammation. Nature 454, 445-454.
19. Packard, K. A., Khan, M. M. (2003) Effects of histamine on Th1/Th2 cytokine balance. Int. Immunopharmacol. 3, 909-920.
20. Skokos, D., Botros, H. G., Demeure, C., Morin, J., Peronet, R., Birkenmeier, G., Boudaly, S., Mecheri, S. (2003) Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J. Immunol. 170, 3037-3045.
21. Yang, X. D., Ai, W., Asfaha, S., Bhagat, G., Friedman, R. A., Jin, G., Park, H., Shykind, B., Diacovo, T. G., Falus, A., et al. (2011) Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells. Nat. Med. 17, 87-95.
22. Van der Pouw Kraan, T. C., Snijders, A., Boeije, L. C., de Groot, E. R., Alewijnse, A. E., Leurs, R., Aarden, L. A. (1998) Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J. Clin. Invest. 102, 1866-1873.
23. Ishikawa, T., Kanda, N., Hau, C. S., Tada, Y., Watanabe, S. (2009) Histamine induces human β-defensin-3 production in human keratinocytes. J. Dermatol. Sci. 56, 121-127.
24. Gibb, D. R., Saleem, S. J., Kang, D. J., Subler, M. A., Conrad, D. H. (2011) ADAM10 overexpression shifts lympho-and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. J. Immunol. 186, 4244-4252.
25. Lilla, J. N., Chen, C. C., Mukai, K., BenBarak, M. J., Franco, C. B., Kalesnikoff, J., Yu, M., Tsai, M., Piliponsky, A. M., Galli, S. J. (2011) Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice. Blood 118, 6930-6938.
26. Camberis, M., Le, G. G., Urban, J., Jr. (2003) Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus. Curr. Protoc. Immunol. Chapter 19, Unit 19.12.
27. Connolly, M. K., Mallen-St, C. J., Bedrosian, A. S., Malhotra, A., Vera, V., Ibrahim, J., Henning, J., Pachter, H. L., Bar-Sagi, D., Frey, A. B., et al. (2010) Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. J. Leukoc. Biol. 87, 713-725.
28. Collins, A. M., Leach, S., Payne, J., Mitchell, A., Dai, Y., Jackson, G. D. (1999) A role for the hepatobiliary system in IgE-mediated intestinal inflammation in the rat. Clin. Exp. Allergy 29, 262-270.
29. Condamine, T., Gabrilovich, D. I. (2011) Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol. 32, 19-25.
30. Dussault, A. A., Pouliot, M. (2006) Rapid and simple comparison of messenger RNA levels using real-time PCR. Biol. Proced. Online 8, 1-10.
31. Zheng, Y., Xu, M., Li, X., Jia, J., Fan, K., Lai, G. (2013) Cimetidine suppresses lung tumor growth in mice through proapoptosis of myeloidderived suppressor cells. Mol. Immunol. 54, 74-83.
32. Bush, R. K. (2004) Etiopathogenesis and management of perennial allergic rhinitis: a state-of-the-art review. Treat. Respir. Med. 3, 45-57.
33. Deshane, J., Zmijewski, J. W., Luther, R., Gaggar, A., Deshane, R., Lai, J. F., Xu, X., Spell, M., Estell, K., Weaver, C. T., et al. (2011) Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol. 4, 503-518.
34. Greten, T. F., Manns, M. P., Korangy, F. (2011) Myeloid derived suppressor cells in human diseases. Int. Immunopharmacol. 11, 802-807.
35. Chan, T., Wiltrout, R. H., Weiss, J. M. (2011) Immunotherapeutic modulation of the suppressive liver and tumor microenvironments. Int. Immunopharmacol. 11, 879-889.
36. Ilkovitch, D., Lopez, D. M. (2009) The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression. Cancer Res. 69, 5514-5521.
37. Saddiqi, H. A., Sarwar, M., Iqbal, Z., Nisa, M., Shahzad, M. A. (2012) Markers/parameters for the evaluation of natural resistance status of small ruminants against gastrointestinal nematodes. Animal 6, 994-1004.
38. Nawa, Y., Ishikawa, N., Tsuchiya, K., Horii, Y., Abe, T., Khan, A. I., Bing, S., Itoh, H., Ide, H., Uchiyama, F. (1994) Selective effector mechanisms for the expulsion of intestinal helminths. Parasite Immunol. 16, 333-338.
39. Shin, E. H., Kim, T. H., Hong, S. J., Park, J. H., Guk, S. M., Chai, J. Y. (2003) Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense. Korean J. Parasitol. 41, 81-87.
40. Yamauchi, K., Piao, H. M., Nakadate, T., Shikanai, T., Nakamura, Y., Ito, H., Mouri, T., Kobayashi, H., Maesawa, C., Sawai, T., et al. (2009) Enhanced goblet cell hyperplasia in HDC knockout mice with allergic airway inflammation. Allergol. Int. 58, 125-134.
41. Elliott, K. A., Osna, N. A., Scofield, M. A., Khan, M. M. (2001) Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells. Int. Immunopharmacol. 1, 1923-1937.
42. Finkelman, F. D., Shea-Donohue, T., Morris, S. C., Gildea, L., Strait, R., Madden, K. B., Schopf, L., Urban J. F., Jr., (2004) Interleukin-4-and interleukin-13-mediated host protection against intestinal nematode parasites. Immunol. Rev. 201, 139-155.
43. Schmidt, J., Fleissner, S., Heimann-Weitschat, I., Lindstaedt, R., Szelenyi, I. (1994) Histamine increases anti-CD3 induced IL-5 production of TH2-type T cells via histamine H2-receptors. Agents Actions 42, 81-85.
44. Jinquan, T., Reimert, C. M., Deleuran, B., Zachariae, C., Simonsen, C., Thestrup-Pedersen, K. (1995) Cetirizine inhibits the in vitro and ex vivo chemotactic response of T lymphocytes and monocytes. J. Allergy Clin. Immunol. 95, 979-986.
45. Walsh, G. M., Moqbel, R., Hartnell, A., Kay, A. B. (1991) Effects of cetirizine on human eosinophil and neutrophil activation in vitro. Int. Arch. Allergy Appl. Immunol. 95, 158-162.
46. Basso, D., Fogar, P., Falconi, M., Fadi, E., Sperti, C., Frasson, C., Greco, E., Tamburrino, D., Teolato, S., Moz, S., et al. (2013) Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study. PLoS One 8, e54824.
47. Jiao, Z. J., Gao, J. J., Hua, S. H., Chen, D. Y., Wang, W. H., Wang, H., Wang, X. H., Xu, H. X. (2012) Correlation between circulating myeloidderived suppressor cells and Th17 cells in esophageal cancer. World J. Gastroenterol. 18, 5454-5461.
48. Sun, H. L., Zhou, X., Xue, Y. F., Wang, K., Shen, Y. F., Mao, J. J., Guo, H. F., Miao, Z. N. (2012) Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma. World J. Gastroenterol. 18, 3303-3309.
49. Diaz-Montero, C. M., Salem, M. L., Nishimura, M. I., Garrett-Mayer, E., Cole, D. J., Montero, A. J. (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol. Immunother. 58, 49-59.
50. Hanahan, D., Coussens, L. M. (2012) Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322.
51. Ruffell, B., Coussens, L. M. (2011) Histamine restricts cancer: nothing to sneeze at. Nat. Med. 17, 43-44.