메뉴 건너뛰기




Volumn 46, Issue 3, 2014, Pages 138-147

Effects of serum bilirubin on atherosclerotic processes

Author keywords

Atherosclerosis; Bilirubin; Cardiovascular disease

Indexed keywords

BILIRUBIN; LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; CARBON MONOXIDE; HEME;

EID: 84899852226     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2014.895588     Document Type: Review
Times cited : (49)

References (82)
  • 1
    • 33845613215 scopus 로고    scopus 로고
    • The heme catabolic pathway and its protective Effects on oxidative stress-mediated diseases
    • Vitek L, Schwertner HA. The heme catabolic pathway and its protective Effects on oxidative stress-mediated diseases. Adv Clin Chem. 2007; 43: 1-57.
    • (2007) Adv Clin Chem. , vol.43 , pp. 1-57
    • Vitek, L.1    Schwertner, H.A.2
  • 2
    • 70449389954 scopus 로고    scopus 로고
    • Bilirubin chemistry and metabolism; Harmful and protective aspects
    • Vitek L, Ostrow JD. Bilirubin chemistry and metabolism; harmful and protective aspects. Curr Pharm Des. 2009; 15: 2869-83.
    • (2009) Curr Pharm Des. , vol.15 , pp. 2869-2883
    • Vitek, L.1    Ostrow, J.D.2
  • 4
    • 48549090696 scopus 로고    scopus 로고
    • Carbon monoxide, reactive oxygen signaling, and oxidative stress
    • Piantadosi CA. Carbon monoxide, reactive oxygen signaling, and oxidative stress. Free Radic Biol Med. 2008; 45: 562-9.
    • (2008) Free Radic Biol Med. , vol.45 , pp. 562-569
    • Piantadosi, C.A.1
  • 5
    • 0028867826 scopus 로고
    • The genetic basis of the reducedexpression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
    • Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, et al. The genetic basis of the reducedexpression of bilirubin UDP- glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med. 1995; 333: 1171-5.
    • (1995) N Engl J Med. , vol.333 , pp. 1171-1175
    • Bosma, P.J.1    Chowdhury, J.R.2    Bakker, C.3    Gantla, S.4    De Boer, A.5    Oostra, B.A.6
  • 6
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol. 1997; 37: 517-54.
    • (1997) Annu Rev Pharmacol Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 7
    • 0028408664 scopus 로고
    • The functional signifi cance of induction of heme oxygenase by oxidant stress
    • Nath KA. The functional signifi cance of induction of heme oxygenase by oxidant stress. J Lab Clin Med. 1994; 123: 461-3.
    • (1994) J Lab Clin Med. , vol.123 , pp. 461-463
    • Nath, K.A.1
  • 8
    • 0015071632 scopus 로고
    • The enzymatic degradation of hemoglobin to bile pigments by macrophages
    • Pimstone NR, Tenhunen R, Seitz PT, Marver HS, Schmid R. The enzymatic degradation of hemoglobin to bile pigments by macrophages. J Exp Med. 1971; 133: 1264-81.
    • (1971) J Exp Med. , vol.133 , pp. 1264-1281
    • Pimstone, N.R.1    Tenhunen, R.2    Seitz, P.T.3    Marver, H.S.4    Schmid, R.5
  • 9
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
    • Ryter SW, Alam J, Choi AM. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev. 2006; 86: 583-650.
    • (2006) Physiol Rev. , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 12
    • 0036182831 scopus 로고    scopus 로고
    • Gilbert syndrome and ischemic heart disease: A protective Effect of elevated bilirubin levels
    • Vitek L, Jirsa M, Brodanova M, Kalab M, Marecek Z, Danzig V, et al. Gilbert syndrome and ischemic heart disease: a protective Effect of elevated bilirubin levels. Atherosclerosis. 2002; 160: 449-56.
    • (2002) Atherosclerosis. , vol.160 , pp. 449-456
    • Vitek, L.1    Jirsa, M.2    Brodanova, M.3    Kalab, M.4    Marecek, Z.5    Danzig, V.6
  • 13
    • 34250323134 scopus 로고    scopus 로고
    • Urinary excretion of oxidative metabolites of bilirubin in subjects with Gilbert syndrome
    • Vitek L, Kraslova I, Muchova L, Novotny L, Yamaguchi T. Urinary excretion of oxidative metabolites of bilirubin in subjects with Gilbert syndrome. J Gastroenterol Hepatol. 2007; 22: 841-5.
    • (2007) J Gastroenterol Hepatol. , vol.22 , pp. 841-845
    • Vitek, L.1    Kraslova, I.2    Muchova, L.3    Novotny, L.4    Yamaguchi, T.5
  • 15
    • 67349088999 scopus 로고    scopus 로고
    • Soluble CD40 ligand and soluble P-selectin levels in Gilbert's syndrome: A link to protection against atherosclerosis?
    • Tapan S, Dogru T, Tasci I, Ercin C N, Ozgurtas T, Erbil M K. Soluble CD40 ligand and soluble P-selectin levels in Gilbert's syndrome: a link to protection against atherosclerosis? Clin Biochem. 2009; 42: 791-5.
    • (2009) Clin Biochem. , vol.42 , pp. 791-795
    • Tapan, S.1    Dogru, T.2    Tasci, I.3    Ercin, C.N.4    Ozgurtas, T.5    Erbil, M.K.6
  • 17
    • 80755187935 scopus 로고    scopus 로고
    • Relationship between bilirubin and C-reactive protein
    • Hwang HJ, Lee SW, Kim SH. Relationship between bilirubin and C-reactive protein. Clin Chem Lab Med. 2011; 49: 1823-8.
    • (2011) Clin Chem Lab Med. , vol.49 , pp. 1823-1828
    • Hwang, H.J.1    Lee, S.W.2    Kim, S.H.3
  • 18
    • 79958067882 scopus 로고    scopus 로고
    • Relationship between bilirubin concentration, coronarYendothelial function, and infl ammatory stress in overweight patients
    • Yoshino S, Hamasaki S, Ishida S, Kataoka T, Yoshikawa A, Oketani N, et al. Relationship between bilirubin concentration, coronarYendothelial function, and infl ammatory stress in overweight patients. J Atheroscler Th romb. 2011; 18: 403-12.
    • (2011) J Atheroscler Th Romb. , vol.18 , pp. 403-412
    • Yoshino, S.1    Hamasaki, S.2    Ishida, S.3    Kataoka, T.4    Yoshikawa, A.5    Oketani, N.6
  • 19
    • 0028084319 scopus 로고
    • Association of low serum concentration of bilirubin with increased risk of coronary artery disease
    • Schwertner HA, Jackson WG, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem. 1994; 40: 18-23.
    • (1994) Clin Chem. , vol.40 , pp. 18-23
    • Schwertner, H.A.1    Jackson, W.G.2    Tolan, G.3
  • 21
    • 0032006981 scopus 로고    scopus 로고
    • Association of smoking and low serum bilirubin antioxidant concentrations
    • Schwertner HA. Association of smoking and low serum bilirubin antioxidant concentrations. Atherosclerosis. 1998; 136: 383-7.
    • (1998) Atherosclerosis. , vol.136 , pp. 383-387
    • Schwertner, H.A.1
  • 22
    • 0034081041 scopus 로고    scopus 로고
    • Comparison of various lipid, lipoprotein, and bilirubin combinations as risk factors for predicting coronary artery disease
    • Schwertner HA, Fischer JR, Jr. Comparison of various lipid, lipoprotein, and bilirubin combinations as risk factors for predicting coronary artery disease. Atherosclerosis. 2000; 150: 381-7.
    • (2000) Atherosclerosis. , vol.150 , pp. 381-387
    • Schwertner, H.A.1    Fischer Jr., J.R.2
  • 23
    • 69049096003 scopus 로고    scopus 로고
    • Low serum bilirubin concentration is associated with coronary artery calcifi cation (CAC)
    • Tanaka M, Fukui M, Tomiyasu K, Akabame S, Nakano K, Hasegawa G, et al. Low serum bilirubin concentration is associated with coronary artery calcifi cation (CAC). Atherosclerosis. 2009; 206: 287-91.
    • (2009) Atherosclerosis. , vol.206 , pp. 287-291
    • Tanaka, M.1    Fukui, M.2    Tomiyasu, K.3    Akabame, S.4    Nakano, K.5    Hasegawa, G.6
  • 24
    • 84884584831 scopus 로고    scopus 로고
    • Elevated serum bilirubin levels are inversely associated with coronary artery atherosclerosis
    • Kang SJ, Kim D, Park HE, Chung GE, Choi SH, Choi SY, et al. Elevated serum bilirubin levels are inversely associated with coronary artery atherosclerosis. Atherosclerosis. 2013; 230: 242-8.
    • (2013) Atherosclerosis. , vol.230 , pp. 242-248
    • Kang, S.J.1    Kim, D.2    Park, H.E.3    Chung, G.E.4    Choi, S.H.5    Choi, S.Y.6
  • 25
    • 27644483425 scopus 로고    scopus 로고
    • High serum bilirubin concentrations preserve coronary fLow reserve and coronary microvascular functions
    • Gullu H, Erdogan D, Tok D, Topcu S, Caliskan M, Ulus T, et al. High serum bilirubin concentrations preserve coronary fLow reserve and coronary microvascular functions. Arterioscler Th romb Vasc Biol. 2005; 25: 2289-94.
    • (2005) Arterioscler Th Romb Vasc Biol. , vol.25 , pp. 2289-2294
    • Gullu, H.1    Erdogan, D.2    Tok, D.3    Topcu, S.4    Caliskan, M.5    Ulus, T.6
  • 26
    • 41049098411 scopus 로고    scopus 로고
    • Gilbert syndrome, UGT1A12 8 allele, and cardiovascular disease risk: Possible protective Effects and therapeutic applications of bilirubin
    • Schwertner H A, Vitek L. Gilbert syndrome, UGT1A12 8 allele, and cardiovascular disease risk: possible protective Effects and therapeutic applications of bilirubin. Atherosclerosis. 2008; 198: 1-11.
    • (2008) Atherosclerosis. , vol.198 , pp. 1-11
    • Schwertner, H.A.1    Vitek, L.2
  • 27
    • 0035873227 scopus 로고    scopus 로고
    • Total serum bilirubin and risk of cardiovascular disease in the Framingham off spring study
    • A1194, 1197
    • Djousse L, Levy D, Cupples LA, Evans JC, D'Agostino RB, Ellison RC. Total serum bilirubin and risk of cardiovascular disease in the Framingham off spring study. Am J Cardiol. 2001; 87: 1196-200; A1194, 1197.
    • (2001) Am J Cardiol. , vol.87 , pp. 1196-1200
    • Djousse, L.1    Levy, D.2    Cupples, L.A.3    Evans, J.C.4    D'Agostino, R.B.5    Ellison, R.C.6
  • 28
    • 0038047678 scopus 로고    scopus 로고
    • Inverse relationship between serum bilirubin and atherosclerosis in men: A meta-analysis of published studies
    • Novotny L, Vitek L. Inverse relationship between serum bilirubin and atherosclerosis in men: a meta-analysis of published studies. Exp Biol Med (Maywood). 2003; 228: 568-71.
    • (2003) Exp Biol Med (Maywood). , vol.228 , pp. 568-571
    • Novotny, L.1    Vitek, L.2
  • 29
    • 70350558555 scopus 로고    scopus 로고
    • Low serum bilirubin level as an independent predictor of stroke incidence: A prospective study in Korean men and women
    • Kimm H, Yun JE, Jo J, Jee SH. Low serum bilirubin level as an independent predictor of stroke incidence: a prospective study in Korean men and women. Stroke. 2009; 40: 3422-7.
    • (2009) Stroke. , vol.40 , pp. 3422-3427
    • Kimm, H.1    Yun, J.E.2    Jo, J.3    Jee, S.H.4
  • 30
    • 49949108687 scopus 로고    scopus 로고
    • Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004
    • e781
    • Perlstein TS, Pande RL, Creager MA, Weuve J, Beckman JA. Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004. Am J Med. 2008; 121: 781-8 e781.
    • (2008) Am J Med. , vol.121 , pp. 781-788
    • Perlstein, T.S.1    Pande, R.L.2    Creager, M.A.3    Weuve, J.4    Beckman, J.A.5
  • 31
    • 33748445757 scopus 로고    scopus 로고
    • The inverse association of elevated serum bilirubin levels witHsubclinical carotid atherosclerosis
    • Vitek L, Novotny L, Sperl M, Holaj R, Spacil J. The inverse association of elevated serum bilirubin levels witHsubclinical carotid atherosclerosis. Cerebrovasc Dis. 2006; 21: 408-14.
    • (2006) Cerebrovasc Dis. , vol.21 , pp. 408-414
    • Vitek, L.1    Novotny, L.2    Sperl, M.3    Holaj, R.4    Spacil, J.5
  • 32
    • 30044437464 scopus 로고    scopus 로고
    • Low serum bilirubin levels are independently and inversely related to impaired fLow-mediated vasodilation and increased carotid intimamedia thickness in both men and women
    • Erdogan D, Gullu H, Yildirim E, Tok D, Kirbas I, Ciftci O, et al. Low serum bilirubin levels are independently and inversely related to impaired fLow-mediated vasodilation and increased carotid intimamedia thickness in both men and women. Atherosclerosis. 2006; 184: 431-7.
    • (2006) Atherosclerosis. , vol.184 , pp. 431-437
    • Erdogan, D.1    Gullu, H.2    Yildirim, E.3    Tok, D.4    Kirbas, I.5    Ciftci, O.6
  • 33
    • 84866480062 scopus 로고    scopus 로고
    • Lower carotid intima media thickness is predicted by higher serum bilirubin in noth non-diabetic and Type 2 diabetic subjects
    • Dullaart RPF, Kappelle PJWH, de Vries R. Lower carotid intima media thickness is predicted by higher serum bilirubin in noth non-diabetic and Type 2 diabetic subjects. Clin Chim Acta. 2012; 414: 161-5.
    • (2012) Clin Chim Acta. , vol.414 , pp. 161-165
    • Dullaart, R.P.F.1    Kappelle, P.J.W.H.2    De Vries, R.3
  • 34
    • 37549065092 scopus 로고    scopus 로고
    • Serum total bilirubin level and prevalent lower-extremity peripheral arterial disease: National HealtHand Nutrition Examination Survey (NHANES) 1999 to 2004
    • Perlstein TS, Pande RL, Beckman JA, Creager MA. Serum total bilirubin level and prevalent lower-extremity peripheral arterial disease: National HealtHand Nutrition Examination Survey (NHANES) 1999 to 2004. Arterioscler Th romb Vasc Biol. 2008; 28: 166-72.
    • (2008) Arterioscler Th Romb Vasc Biol. , vol.28 , pp. 166-172
    • Perlstein, T.S.1    Pande, R.L.2    Beckman, J.A.3    Creager, M.A.4
  • 35
    • 62749195623 scopus 로고    scopus 로고
    • Serum bilirubin is inversely associated with insulin resistance and metabolic syndrome among children and adolescents
    • Lin LY, Kuo HK, Hwang JJ, Lai LP, Chiang FT, Tseng CD, et al. Serum bilirubin is inversely associated with insulin resistance and metabolic syndrome among children and adolescents. Atherosclerosis. 2009; 203: 563-8.
    • (2009) Atherosclerosis. , vol.203 , pp. 563-568
    • Lin, L.Y.1    Kuo, H.K.2    Hwang, J.J.3    Lai, L.P.4    Chiang, F.T.5    Tseng, C.D.6
  • 36
    • 84864101453 scopus 로고    scopus 로고
    • High total bilirubin as a protective factor for diabetes mellitus: An analysis of NHANES data from 1999-2006
    • Cheriyath P, Gorrepati VS, Peters I, Nookala V, Murphy ME, Srouji N, et al. High total bilirubin as a protective factor for diabetes mellitus: an analysis of NHANES data from 1999-2006. J Clin Med Res. 2010; 2: 201-6.
    • (2010) J Clin Med Res. , vol.2 , pp. 201-206
    • Cheriyath, P.1    Gorrepati, V.S.2    Peters, I.3    Nookala, V.4    Murphy, M.E.5    Srouji, N.6
  • 37
    • 77954692327 scopus 로고    scopus 로고
    • Serum bilirubin predicts long-term clinical outcomes in patients with cardiac syndrome X
    • Huang SS, Huang PH, Leu HB, Wu TC, Lin SJ, Chen JW. Serum bilirubin predicts long-term clinical outcomes in patients with cardiac syndrome X. Heart. 2010; 96: 1227-32.
    • (2010) Heart. , vol.96 , pp. 1227-1232
    • Huang, S.S.1    Huang, P.H.2    Leu, H.B.3    Wu, T.C.4    Lin, S.J.5    Chen, J.W.6
  • 38
    • 82955187697 scopus 로고    scopus 로고
    • Association of lower total bilirubin level with statin usage: The United States national healt hand nutrition examination survey 1999-2008
    • Ong KL, Wu BJ, Cheung BM, Barter PJ, Rye KA. Association of lower total bilirubin level with statin usage: the United States National HealtHand Nutrition Examination Survey 1999-2008. Atherosclerosis. 2011; 219: 728-33.
    • (2011) Atherosclerosis. , vol.219 , pp. 728-733
    • Ong, K.L.1    Wu, B.J.2    Cheung, B.M.3    Barter, P.J.4    Rye, K.A.5
  • 39
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifi cations in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifi cations in atherosclerosis. Physiol Rev. 2004; 84: 1381-478.
    • (2004) Physiol Rev. , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr., J.F.2
  • 40
    • 33750969074 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel drug target for atherosclerotic diseases?
    • Stocker R, Perrella MA. Heme oxygenase-1: a novel drug target for atherosclerotic diseases? Circulation. 2006; 114: 2178-89.
    • (2006) Circulation. , vol.114 , pp. 2178-2189
    • Stocker, R.1    Perrella, M.A.2
  • 41
    • 4544386856 scopus 로고    scopus 로고
    • Antioxidant activities of bile pigments
    • Stocker R. Antioxidant activities of bile pigments. Antioxid Redox Signal. 2004; 6: 841-9.
    • (2004) Antioxid Redox Signal. , vol.6 , pp. 841-849
    • Stocker, R.1
  • 42
    • 0034660185 scopus 로고    scopus 로고
    • Dynamics of heme oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress
    • Clark J E, Foresti R, Green C J, Motterlini R. Dynamics of heme oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress. Biochem J. 2000; 348(Pt 3): 615-19.
    • (2000) Biochem J. , vol.348 , Issue.PART 3 , pp. 615-619
    • Clark, J.E.1    Foresti, R.2    Green, C.J.3    Motterlini, R.4
  • 43
    • 0028313015 scopus 로고
    • Unconjugated bilirubin inhibits the oxidation of human low density lipoprotein better than Trolox
    • Wu TW, Fung KP, Yang CC. Unconjugated bilirubin inhibits the oxidation of human low density lipoprotein better than Trolox. Life Sci. 1994; 54: P477-81.
    • (1994) Life Sci. , vol.54
    • Wu, T.W.1    Fung, K.P.2    Yang, C.C.3
  • 45
  • 46
    • 0036145130 scopus 로고    scopus 로고
    • Changes in low-density lipoprotein electronegativity and oxidizability aft er aerobic exercise are related to the increase in associated non-esterifi ed fatty acids
    • Benitez S, Sanchez-Quesada JL, Lucero L, Arcelus R, Ribas V, Jorba O, et al. Changes in low-density lipoprotein electronegativity and oxidizability aft er aerobic exercise are related to the increase in associated non-esterifi ed fatty acids. Atherosclerosis. 2002; 160: 223-32.
    • (2002) Atherosclerosis. , vol.160 , pp. 223-232
    • Benitez, S.1    Sanchez-Quesada, J.L.2    Lucero, L.3    Arcelus, R.4    Ribas, V.5    Jorba, O.6
  • 47
    • 0030930697 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL
    • Ishikawa K, Navab M, Leitinger N, Fogelman AM, Lusis AJ. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J Clin Invest. 1997; 100: 1209-16.
    • (1997) J Clin Invest. , vol.100 , pp. 1209-1216
    • Ishikawa, K.1    Navab, M.2    Leitinger, N.3    Fogelman, A.M.4    Lusis, A.J.5
  • 48
    • 0042763565 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 in monocytes suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: Role of bilirubin and carbon monoxide generated by the enzyme
    • Morita T, Imai T, Yamaguchi T, Sugiyama T, Katayama S, Yoshino G. Induction of heme oxygenase-1 in monocytes suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: role of bilirubin and carbon monoxide generated by the enzyme. Antioxid Redox Signal. 2003; 5: 439-47.
    • (2003) Antioxid Redox Signal. , vol.5 , pp. 439-447
    • Morita, T.1    Imai, T.2    Yamaguchi, T.3    Sugiyama, T.4    Katayama, S.5    Yoshino, G.6
  • 50
    • 0035574676 scopus 로고    scopus 로고
    • Increasedexpression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions
    • Nakayama M, Takahashi K, Komaru T, Fukuchi M, Shioiri H, Sato K, et al. Increasedexpression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions. Arterioscler Th romb Vasc Biol. 2001; 21: 1373-7.
    • (2001) Arterioscler Th Romb Vasc Biol. , vol.21 , pp. 1373-1377
    • Nakayama, M.1    Takahashi, K.2    Komaru, T.3    Fukuchi, M.4    Shioiri, H.5    Sato, K.6
  • 51
    • 0033570168 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress: Role of bilirubin generated by the enzyme
    • Hayashi S, Takamiya R, Yamaguchi T, Matsumoto K, Tojo SJ, Tamatani T, et al. Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress: role of bilirubin generated by the enzyme. Circ Res. 1999; 85: 663-71.
    • (1999) Circ Res. , vol.85 , pp. 663-671
    • Hayashi, S.1    Takamiya, R.2    Yamaguchi, T.3    Matsumoto, K.4    Tojo, S.J.5    Tamatani, T.6
  • 53
    • 77951160872 scopus 로고    scopus 로고
    • Bilirubin Effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway
    • Mazzone GL, Rigato I, Ostrow JD, Tiribelli C. Bilirubin Effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway. Biosci Trends. 2009; 3: 151-7.
    • (2009) Biosci Trends. , vol.3 , pp. 151-157
    • Mazzone, G.L.1    Rigato, I.2    Ostrow, J.D.3    Tiribelli, C.4
  • 54
    • 23844507814 scopus 로고    scopus 로고
    • Bilirubin: A naturaLinhibitor of vascular smooth muscle cell proliferation
    • Ollinger R, Bilban M, Erat A, Froio A, McDaid J, Tyagi S, et al. Bilirubin: a naturaLinhibitor of vascular smooth muscle cell proliferation. Circulation. 2005; 112: 1030-9.
    • (2005) Circulation. , vol.112 , pp. 1030-1039
    • Ollinger, R.1    Bilban, M.2    Erat, A.3    Froio, A.4    McDaid, J.5    Tyagi, S.6
  • 56
    • 84865964718 scopus 로고    scopus 로고
    • Bilirubin inhibits neointima formation and vascular smooth muscle cell proliferation and migration
    • Peyton KJ, Shebib AR, Azam MA, Liu XM, Tulis DA, Durante W. Bilirubin inhibits neointima formation and vascular smooth muscle cell proliferation and migration. Front Pharmacol. 2012; 3: 48.
    • (2012) Front Pharmacol. , vol.3 , pp. 48
    • Peyton, K.J.1    Shebib, A.R.2    Azam, M.A.3    Liu, X.M.4    Tulis, D.A.5    Durante, W.6
  • 57
    • 84860847500 scopus 로고    scopus 로고
    • Essential roles of Raf/extracellular signal-regulated kinase/mitogen-activated protein kinase pathway, YY1, and Ca2 infl uXin growth arrest of human vascular smooth muscle cells by bilirubin
    • Stoeckius M, Erat A, Fujikawa T, Hiromura M, Koulova A, Otterbein L, et al. Essential roles of Raf/extracellular signal-regulated kinase/mitogen- activated protein kinase pathway, YY1, and Ca2 infl uXin growth arrest of human vascular smooth muscle cells by bilirubin. J Biol Chem. 2012; 287: 15418-26.
    • (2012) J Biol Chem. , vol.287 , pp. 15418-15426
    • Stoeckius, M.1    Erat, A.2    Fujikawa, T.3    Hiromura, M.4    Koulova, A.5    Otterbein, L.6
  • 58
    • 79960872513 scopus 로고    scopus 로고
    • Serum levels of bilirubin as an independent predictor of coronary in-stent restenosis: A new look at an old molecule
    • Kuwano T, Miura S, Shirai K, Ike A, Mori K, Shimizu T, et al. Serum levels of bilirubin as an independent predictor of coronary in-stent restenosis: a new look at an old molecule. J Atheroscler Th romb. 2011; 18: 574-83.
    • (2011) J Atheroscler Th Romb. , vol.18 , pp. 574-583
    • Kuwano, T.1    Miura, S.2    Shirai, K.3    Ike, A.4    Mori, K.5    Shimizu, T.6
  • 59
    • 33745125783 scopus 로고    scopus 로고
    • Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type i diabetes
    • Rodella L, Lamon B D, Rezzani R, Sangras B, Goodman A I, Falck JR, et al. Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes. Free Radic Biol Med. 2006; 40: 2198-205.
    • (2006) Free Radic Biol Med. , vol.40 , pp. 2198-2205
    • Rodella, L.1    Lamon, B.D.2    Rezzani, R.3    Sangras, B.4    Goodman, A.I.5    Falck, J.R.6
  • 61
    • 79955914489 scopus 로고    scopus 로고
    • Three-dimensional cryoEM reconstruction of native LDL particles to 16A resolution at physiological body temperature
    • Kumar V, Butcher SJ, Oorni K, Engelhardt P, Heikkonen J, Kaski K, et al. Three-dimensional cryoEM reconstruction of native LDL particles to 16A resolution at physiological body temperature. PLoS One. 2011; 6: e18841.
    • (2011) PLoS One. , vol.6
    • Kumar, V.1    Butcher, S.J.2    Oorni, K.3    Engelhardt, P.4    Heikkonen, J.5    Kaski, K.6
  • 62
    • 0030984372 scopus 로고    scopus 로고
    • Relationship between bilirubin, apolipoprotein B, and coronary artery disease
    • Levinson SS. Relationship between bilirubin, apolipoprotein B, and coronary artery disease. Ann Clin Lab Sci. 1997; 27: 185-92.
    • (1997) Ann Clin Lab Sci. , vol.27 , pp. 185-192
    • Levinson, S.S.1
  • 63
    • 0030974279 scopus 로고    scopus 로고
    • Abnormalities of serum apo A1 containing lipoprotein particles in patients with primary biliary cirrhosis
    • O' Kane MJ, Lynch PL, Callender ME, Trimble ER. Abnormalities of serum apo A1 containing lipoprotein particles in patients with primary biliary cirrhosis. Atherosclerosis. 1997; 131: 203-10.
    • (1997) Atherosclerosis. , vol.131 , pp. 203-210
    • O'Kane, M.J.1    Lynch, P.L.2    Callender, M.E.3    Trimble, E.R.4
  • 64
    • 20444389826 scopus 로고    scopus 로고
    • Serum amyloid A-luciferase transgenic mice: Response to sepsis, acute arthritis, and contact hypersensitivity and the Effects of proteasome inhibition
    • Zhang N, Ahsan M H, Purchio A F, West D B. Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the Effects of proteasome inhibition. J Immunol. 2005; 174: 8125-34.
    • (2005) J Immunol. , vol.174 , pp. 8125-8134
    • Zhang, N.1    Ahsan, M.H.2    Purchio, A.F.3    West, D.B.4
  • 65
    • 84876231617 scopus 로고    scopus 로고
    • The inverse relation of HDL anti-oxidative functionality with serum amyloid a is lost in metabolic syndrome subjects
    • Dullaart RP, de Boer JF, Annema W, Tietge UJ. The inverse relation of HDL anti-oxidative functionality with serum amyloid a is lost in metabolic syndrome subjects. Obesity (Silver Spring). 2013; 21: 361-6.
    • (2013) Obesity (Silver Spring). , vol.21 , pp. 361-366
    • Dullaart, R.P.1    De Boer, J.F.2    Annema, W.3    Tietge, U.J.4
  • 66
    • 84887513522 scopus 로고    scopus 로고
    • High sensitive C-reactive protein and serum amyloid A are inversely related to serum bilirubin: Effect-modifi cation by metabolic syndrome
    • Deetman PE, Bakker SJ, Dullaart RP. High sensitive C-reactive protein and serum amyloid A are inversely related to serum bilirubin: Effect-modifi cation by metabolic syndrome. Cardiovasc Diabetol. 2013; 12: 166.
    • (2013) Cardiovasc Diabetol. , vol.12 , pp. 166
    • Deetman, P.E.1    Bakker, S.J.2    Dullaart, R.P.3
  • 67
    • 0035177104 scopus 로고    scopus 로고
    • Remnant-like particle (RLP) cholesteroLis an independent cardiovascular disease risk factor in women: Results from the Framingham Heart Study
    • McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PW, Ordovas JM, et al. Remnant-like particle (RLP) cholesteroLis an independent cardiovascular disease risk factor in women: results from the Framingham Heart Study. Atherosclerosis. 2001; 154: 229-36.
    • (2001) Atherosclerosis. , vol.154 , pp. 229-236
    • McNamara, J.R.1    Shah, P.K.2    Nakajima, K.3    Cupples, L.A.4    Wilson, P.W.5    Ordovas, J.M.6
  • 68
    • 19544370917 scopus 로고    scopus 로고
    • Heme oxygenase and the cardiovascularrenal system
    • Abraham NG, Kappas A. Heme oxygenase and the cardiovascularrenal system. Free Radic Biol Med. 2005; 39: 1-25.
    • (2005) Free Radic Biol Med. , vol.39 , pp. 1-25
    • Abraham, N.G.1    Kappas, A.2
  • 69
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling
    • Yet SF, Layne MD, Liu X, Chen YH, Ith B, Sibinga NE, et al. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. FASEB J. 2003; 17: 1759-61.
    • (2003) FASEB J. , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibinga, N.E.6
  • 70
    • 0034959256 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects against vascular constriction and proliferation
    • Duckers HJ, Boehm M, True AL, Yet SF, San H, Park JL, et al. Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med. 2001; 7: 693-8.
    • (2001) Nat Med. , vol.7 , pp. 693-698
    • Duckers, H.J.1    Boehm, M.2    True, A.L.3    Yet, S.F.4    San, H.5    Park, J.L.6
  • 71
    • 0035920256 scopus 로고    scopus 로고
    • Cardiac-specifi c expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice
    • Yet SF, Tian R, Layne MD, Wang ZY, Maemura K, Solovyeva M, et al. Cardiac-specifi c expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circ Res. 2001; 89: 168-73.
    • (2001) Circ Res. , vol.89 , pp. 168-173
    • Yet, S.F.1    Tian, R.2    Layne, M.D.3    Wang, Z.Y.4    Maemura, K.5    Solovyeva, M.6
  • 72
    • 0030886381 scopus 로고    scopus 로고
    • Heme oxygenase 1 is required for mammalian iron reutilization
    • Poss KD, Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA. 1997; 94: 10919-24.
    • (1997) Proc Natl Acad Sci USA. , vol.94 , pp. 10919-10924
    • Poss, K.D.1    Tonegawa, S.2
  • 73
    • 34547787584 scopus 로고    scopus 로고
    • Pharmacologic induction of heme oxygenase 1 reduces acute infl ammatory arthritis in mice
    • Benallaoua M, Francois M, Batteux F, Thelier N, Shyy JY, Fitting C, et al. Pharmacologic induction of heme oxygenase 1 reduces acute infl ammatory arthritis in mice. Arthritis Rheum. 2007; 56: 2585-94.
    • (2007) Arthritis Rheum. , vol.56 , pp. 2585-2594
    • Benallaoua, M.1    Francois, M.2    Batteux, F.3    Thelier, N.4    Shyy, J.Y.5    Fitting, C.6
  • 74
    • 0034071424 scopus 로고    scopus 로고
    • Carbon monoxide has anti-infl ammatory Effects involving the mitogen-activated protein kinase pathway
    • Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, et al. Carbon monoxide has anti-infl ammatory Effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000; 6: 422-8.
    • (2000) Nat Med. , vol.6 , pp. 422-428
    • Otterbein, L.E.1    Bach, F.H.2    Alam, J.3    Soares, M.4    Tao Lu, H.5    Wysk, M.6
  • 75
    • 84871771750 scopus 로고    scopus 로고
    • Genetically elevated bilirubin and risk of ischaemic heart disease: Three Mendelian randomization studies and a metaanalysis
    • Stender S, Frikke-Schmidt R, Nordestgaard BG, Grande P, Tybjaerg-Hansen A. Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a metaanalysis. J Intern Med. 2013; 273: 59-68.
    • (2013) J Intern Med. , vol.273 , pp. 59-68
    • Stender, S.1    Frikke-Schmidt, R.2    Nordestgaard, B.G.3    Grande, P.4    Tybjaerg-Hansen, A.5
  • 76
    • 0037230622 scopus 로고    scopus 로고
    • Inherited disorders of bilirubin metabolism
    • Bosma PJ. Inherited disorders of bilirubin metabolism. J Hepatol. 2003; 38: 107-17.
    • (2003) J Hepatol. , vol.38 , pp. 107-117
    • Bosma, P.J.1
  • 78
    • 0038574981 scopus 로고    scopus 로고
    • Bilirubin concentration UGT1A1 28 polymorphism and coronary artery disease
    • Schwertner HA. Bilirubin concentration, UGT1A1 28 polymorphism, and coronary artery disease. Clin Chem. 2003; 49: 1039-40.
    • (2003) Clin Chem. , vol.49 , pp. 1039-1040
    • Schwertner, H.A.1
  • 79
    • 33845532124 scopus 로고    scopus 로고
    • Further evidence that the UGT1A1 28 allele is not associated with coronary heart disease: The ECTIM Study
    • Gajdos V, Petit FM, Perret C, Mollet-Boudjemline A, Colin P, Capel L, et al. Further evidence that the UGT1A1 28 allele is not associated with coronary heart disease: The ECTIM Study. Clin Chem. 2006; 52: 2313-14.
    • (2006) Clin Chem. , vol.52 , pp. 2313-2314
    • Gajdos, V.1    Petit, F.M.2    Perret, C.3    Mollet-Boudjemline, A.4    Colin, P.5    Capel, L.6
  • 80
    • 33749524440 scopus 로고    scopus 로고
    • Association between the UGT1A1 28 allele, bilirubin levels, and coronary heart disease in the Framingham heart study
    • Lin JP, O' Donnell CJ, Schwaiger JP, Cupples LA, Lingenhel A, Hunt SC, et al. Association between the UGT1A1 28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation. 2006; 114: 1476-81.
    • (2006) Circulation. , vol.114 , pp. 1476-1481
    • Lin, J.P.1    O'Donnell, C.J.2    Schwaiger, J.P.3    Cupples, L.A.4    Lingenhel, A.5    Hunt, S.C.6
  • 81
    • 84874950022 scopus 로고    scopus 로고
    • Breast milk jaundice: Effect of bacteria present in breast milk and infant feces
    • Tuzun F, Kumral A, Duman N, Ozkan H. Breast milk jaundice: Effect of bacteria present in breast milk and infant feces. J Pediatr Gastroenterol Nutr. 2013; 56: 328-32.
    • (2013) J Pediatr Gastroenterol Nutr. , vol.56 , pp. 328-332
    • Tuzun, F.1    Kumral, A.2    Duman, N.3    Ozkan, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.