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Volumn 9, Issue 1, 2014, Pages

Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation

Author keywords

[No Author keywords available]

Indexed keywords

HOLOENZYME; METHYLTRANSFERASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN LCMT 1; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

EID: 84899844259     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086955     Document Type: Article
Times cited : (20)

References (30)
  • 1
    • 70350340056 scopus 로고    scopus 로고
    • Serine/threonine phosphatases: Mechanism through structure
    • Shi Y (2009) Serine/threonine phosphatases: mechanism through structure. Cell 139: 468-484.
    • (2009) Cell , vol.139 , pp. 468-484
    • Shi, Y.1
  • 3
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • DOI 10.1042/0264-6021:3530417
    • Janssens V, Goris J (2001) Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J 353: 417-439. (Pubitemid 32158309)
    • (2001) Biochemical Journal , vol.353 , Issue.3 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 4
    • 0034009389 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A panoply of enzymes
    • Virshup DM (2000) Protein phosphatase 2A: a panoply of enzymes. Curr Opin Cell Biol 12: 180-185.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 180-185
    • Virshup, D.M.1
  • 5
    • 0034331359 scopus 로고    scopus 로고
    • Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits
    • Tolstykh T, Lee J, Vafai S, Stock JB (2000) Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits. Embo J 19: 5682-5691.
    • (2000) Embo J , vol.19 , pp. 5682-5691
    • Tolstykh, T.1    Lee, J.2    Vafai, S.3    Stock, J.B.4
  • 6
    • 0030821233 scopus 로고    scopus 로고
    • Protein phosphatase 2A subunit assembly: The catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen
    • Ogris E, Gibson DM, Pallas DC (1997) Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen. Oncogene 15: 911-917. (Pubitemid 27399552)
    • (1997) Oncogene , vol.15 , Issue.8 , pp. 911-917
    • Ogris, E.1    Gibson, D.M.2    Pallas, D.C.3
  • 7
    • 0033560729 scopus 로고    scopus 로고
    • Methylated C-terminal leucine residue of PP2A catalytic subunit is important for binding of regulatory Balpha subunit
    • DOI 10.1042/0264-6021:3390241
    • Bryant JC, Westphal RS, Wadzinski BE (1999) Methylated C-terminal leucine residue of PP2A catalytic subunit is important for binding of regulatory Balpha subunit. Biochem J 339 (Pt 2): 241-246. (Pubitemid 29209953)
    • (1999) Biochemical Journal , vol.339 , Issue.2 , pp. 241-246
    • Bryant, J.C.1    Westphal, R.S.2    Wadzinski, B.E.3
  • 8
    • 0027184102 scopus 로고
    • Protein phosphatase 2A catalytic subunit is methyl-esterified at its carboxyl terminus by a novel methyltransferase
    • Lee J, Stock J (1993) Protein phosphatase 2A catalytic subunit is methylesterified at its carboxyl terminus by a novel methyltransferase. J Biol Chem 268: 19192-19195. (Pubitemid 23270686)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.26 , pp. 19192-19195
    • Lee, J.1    Stock, J.2
  • 10
    • 41149175685 scopus 로고    scopus 로고
    • Structural Mechanism of Demethylation and Inactivation of Protein Phosphatase 2A
    • DOI 10.1016/j.cell.2008.02.041, PII S0092867408003309
    • Xing Y, Li Z, Chen Y, Stock JB, Jeffrey PD, et al. (2008) Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell 133: 154-163. (Pubitemid 351442993)
    • (2008) Cell , vol.133 , Issue.1 , pp. 154-163
    • Xing, Y.1    Li, Z.2    Chen, Y.3    Stock, J.B.4    Jeffrey, P.D.5    Shi, Y.6
  • 11
    • 79251553753 scopus 로고    scopus 로고
    • The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1
    • Stanevich V, Jiang L, Satyshur KA, Li Y, Jeffrey PD, et al. (2011) The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1. Mol Cell 41: 331-342.
    • (2011) Mol Cell , vol.41 , pp. 331-342
    • Stanevich, V.1    Jiang, L.2    Satyshur, K.A.3    Li, Y.4    Jeffrey, P.D.5
  • 12
    • 84893810920 scopus 로고    scopus 로고
    • Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone
    • doi:10.1038/cr.2013.138
    • Guo F, Stanevich V, Wlodarchak N, Jiang L, Satyshur KA, et al. (2013) Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone. Cell Research doi:10.1038/cr.2013.138.
    • (2013) Cell Research
    • Guo, F.1    Stanevich, V.2    Wlodarchak, N.3    Jiang, L.4    Satyshur, K.A.5
  • 13
    • 0033534405 scopus 로고    scopus 로고
    • The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
    • DOI 10.1016/S0092-8674(00)80963-0
    • Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D (1999) The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96: 99-110. (Pubitemid 29044157)
    • (1999) Cell , vol.96 , Issue.1 , pp. 99-110
    • Groves, M.R.1    Hanlon, N.2    Turowski, P.3    Hemmings, B.A.4    Barford, D.5
  • 14
    • 0028082299 scopus 로고
    • Molecular model of the A subunit of protein phosphatase 2A: Interaction with other subunits and tumor antigens
    • Ruediger R, Hentz M, Fait J, Mumby M, Walter G (1994) Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. J Virol 68: 123-129.
    • (1994) J Virol , vol.68 , pp. 123-129
    • Ruediger, R.1    Hentz, M.2    Fait, J.3    Mumby, M.4    Walter, G.5
  • 15
    • 0026661827 scopus 로고
    • Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus
    • Ruediger R, Roeckel D, Fait J, Bergqvist A, Magnusson G, et al. (1992) Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus. Mol Cell Biol 12: 4872-4882.
    • (1992) Mol Cell Biol , vol.12 , pp. 4872-4882
    • Ruediger, R.1    Roeckel, D.2    Fait, J.3    Bergqvist, A.4    Magnusson, G.5
  • 16
    • 34250356465 scopus 로고    scopus 로고
    • Generation of active protein phosphatase 2A is coupled to holoenzyme assembly
    • Hombauer H, Weismann D, Mudrak I, Stanzel C, Fellner T, et al. (2007) Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5: e155.
    • (2007) PLoS Biol , vol.5
    • Hombauer, H.1    Weismann, D.2    Mudrak, I.3    Stanzel, C.4    Fellner, T.5
  • 17
    • 33750006297 scopus 로고    scopus 로고
    • Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
    • DOI 10.1016/j.cell.2006.09.025, PII S0092867406012293
    • Xing Y, Xu Y, Chen Y, Jeffrey PD, Chao Y, et al. (2006) Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell 127: 341-353. (Pubitemid 44572378)
    • (2006) Cell , vol.127 , Issue.2 , pp. 341-353
    • Xing, Y.1    Xu, Y.2    Chen, Y.3    Jeffrey, P.D.4    Chao, Y.5    Lin, Z.6    Li, Z.7    Strack, S.8    Stock, J.B.9    Shi, Y.10
  • 19
  • 22
    • 84879888186 scopus 로고    scopus 로고
    • Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation
    • Wlodarchak N, Guo F, Satyshur KA, Jiang L, Jeffrey PD, et al. (2013) Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res 23: 931-946.
    • (2013) Cell Res , vol.23 , pp. 931-946
    • Wlodarchak, N.1    Guo, F.2    Satyshur, K.A.3    Jiang, L.4    Jeffrey, P.D.5
  • 25
    • 52049100425 scopus 로고    scopus 로고
    • Structure of a protein phosphatase 2A holoenzyme: Insights into B55-mediated Tau dephosphorylation
    • Xu Y, Chen Y, Zhang P, Jeffrey PD, Shi Y (2008) Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation. Mol Cell 31: 873-885.
    • (2008) Mol Cell , vol.31 , pp. 873-885
    • Xu, Y.1    Chen, Y.2    Zhang, P.3    Jeffrey, P.D.4    Shi, Y.5
  • 26
    • 77249156811 scopus 로고    scopus 로고
    • PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis
    • Grinthal A, Adamovic I, Weiner B, Karplus M, Kleckner N (2010) PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis. Proc Natl Acad Sci U S A 107: 2467-2472.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2467-2472
    • Grinthal, A.1    Adamovic, I.2    Weiner, B.3    Karplus, M.4    Kleckner, N.5
  • 27
    • 0035883164 scopus 로고    scopus 로고
    • Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes
    • DOI 10.1002/ijc.1423
    • Colella S, Ohgaki H, Ruediger R, Yang F, Nakamura M, et al. (2001) Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes. Int J Cancer 93: 798-804. (Pubitemid 32756748)
    • (2001) International Journal of Cancer , vol.93 , Issue.6 , pp. 798-804
    • Colella, S.1    Ohgaki, H.2    Ruediger, R.3    Yang, F.4    Nakamura, M.5    Fujisawa, H.6    Kleihues, P.7    Walter, G.8
  • 28
    • 0035804217 scopus 로고    scopus 로고
    • Disruption of protein phosphatase 2a subunit interaction in human cancers with mutations in the Aalpha subunit gene
    • Ruediger R, Pham HT, Walter G (2001) Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. Oncogene 20: 10-15. (Pubitemid 32142333)
    • (2001) Oncogene , vol.20 , Issue.1 , pp. 10-15
    • Ruediger, R.1    Pham, H.T.2    Walter, G.3
  • 29
    • 61649127812 scopus 로고    scopus 로고
    • From promiscuity to precision: Protein phosphatases get a makeover
    • Virshup DM, Shenolikar S (2009) From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 33: 537-545.
    • (2009) Mol Cell , vol.33 , pp. 537-545
    • Virshup, D.M.1    Shenolikar, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.